1. Kishan Dholakia

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    1. Mentioned In 13 Articles

    2. Depth-resolved multimodal imaging: Wavelength Modulated Spatially Offset Raman Spectroscopy with Optical Coherence Tomography

      Depth-resolved multimodal imaging: Wavelength Modulated Spatially Offset Raman Spectroscopy with Optical Coherence Tomography
      A major challenge in biophotonics is multimodal imaging to obtain both morphological and molecular information at depth. We demonstrate a hybrid approach integrating optical coherence tomography (OCT) with wavelength modulated spatially offset Raman spectroscopy (WM-SORS). With depth co-localization obtained from the OCT, we can penetrate 1.2mm deep into the strong scattering media (lard) to acquire up to a 14-fold enhancement of a Raman signal from a hidden target (Polystyrene ...
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    3. Internal physiology of live krill revealed using new aquaria techniques and mixed optical microscopy and optical coherence tomography (OCT) imaging techniques

      Internal physiology of live krill revealed using new aquaria techniques and mixed optical microscopy and optical coherence tomography (OCT) imaging techniques
      The accurate observation of physiological changes on in vivo samples of important animal species such as Euphausia superba (Antarctic krill) is an important goal in helping to understand how environmental changes can affect animal development. Using a custom made krill trap, live un-anaesthetized krill were confined for seven hours, during which three hours of optical imaging were obtained and no subsequent ill effects observed. The trap enabled two imaging methods ...
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    4. Feature Of The Week 11/30/14: Application of OCT to Imaging Subsurface Structure of Antarctic Krill

      Feature Of The Week 11/30/14: Application of OCT to Imaging Subsurface Structure of Antarctic Krill
      Many small open ocean animals, such as Antarctic krill, are an important part of marine ecosystems. To discover what will happen to animals such as krill in a changing ocean, experiments are run in aquaria where conditions can be controlled to simulate water characteristics predicted to occur in the future. The response of individual animals to changing water conditions can be hard to observe, and with current observation techniques it ...
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    5. The Application of Optical Coherence Tomography to Image Subsurface Tissue Structure of Antarctic Krill Euphausia superba

      The Application of Optical Coherence Tomography to Image Subsurface Tissue Structure of Antarctic Krill Euphausia superba
      ... School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, Fife, United Kingdom X * Kishan Dholakia, Affiliation: SUPA, School of Physics and Astronomy, University of St Andrews, North Haugh, St...
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    6. Combined information from Raman spectroscopy and optical coherence tomography for enhanced diagnostic accuracy in tissue discrimination

      Combined information from Raman spectroscopy and optical coherence tomography for enhanced diagnostic accuracy in tissue discrimination
      ... accuracy in tissue discrimination Praveen C. Ashok ; Bavishna B. Praveen ; Nicola Bellini ; Andrew Riches ; Kishan Dholakia ; C. Simon Herrington; Combined information from Raman spectroscopy and optical coherence tomo...
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    7. Feature Of The Week 10/27/13: University of St. Andrews Reports on Multi-Modal OCT and Raman Discrimination of Colon Cancer

      Feature Of The Week 10/27/13: University of St. Andrews Reports on Multi-Modal OCT and Raman Discrimination of Colon Cancer
      Raman spectroscopy and Optical Coherence Tomography (OCT) are two optical tools that have shown potential to be used for discriminating between normal and abnormal tissue types. Although both of these non-invasive techniques are capable of discriminating between normal and tumour tissues, in many cases, they are unable individually to provide both the high specificity and high sensitivity required for disease diagnosis. Raman spectroscopy and OCT provides complementary information. While Raman ...
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    8. Multi-modal approach using Raman spectroscopy and optical coherence tomography for the discrimination of colonic adenocarcinoma from normal colon

      Multi-modal approach using Raman spectroscopy and optical coherence tomography for the discrimination of colonic adenocarcinoma from normal colon
      ...n »View Author Affiliations Praveen C. Ashok,^1,^* Bavishna B. Praveen,^1 Nicola Bellini,^1 Andrew Riches,^2 Kishan Dholakia,^1 and C. Simon Herrington^2,^3 ^1SUPA, School of Physics & Astronomy, North Haugh, Universi...
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    9. Optical Coherence Tomography

      Optical Coherence Tomography
      An optical coherence tomography system comprising a light source (a) and a probe (e) that has a window at a front facing end. The window has an inner face (i) that has an anti-reflection surface and allows light from the source to pass through it, and an outer face (j) that reflects some of the light from the source and transmits some of the light to and from the sample ...
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    10. Tissue surface as the reference arm in Fourier domain optical coherence tomography

      Tissue surface as the reference arm in Fourier domain optical coherence tomography
      We present a simple method applicable to common-path Fourier domain optical coherence tomography (OCT) in which the tissue surface is used as the reference arm. We propose using aluminium hydroxide powder as a potential tissue surface diffuser to allow wider application of this method. This technique allows one to avoid placing a reference arm reflective element, such as glass plate, on tissue, and intrinsically avoids both coherent and complex conjugate ...
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    11. Optical Coherence Tomography

      Optical Coherence Tomography
      An optical coherence tomography system comprising a light source (a) and a probe (e) that has a window at a front facing end. The window has an inner face (i) that has an anti-reflection surface and allows light from the source to pass through it, and an outer face (j) that reflects some of the light from the source and transmits some of the light to and from the sample ...
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    12. 1-13 of 13
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  2. About Kishan Dholakia

    Kishan Dholakia

    Kishan Dholakia is a Professor of Physics at the University of St Andrews in Scotland. His work spans fundamental photonics right through to applications in biomedicine, He heads a vibrant group of ~25 people. He has published more than 250 journal publications, including over 12 papers in Nature/Science group journals, has over 9500 citations and a h-index of 55 (scopus). He is a fellow of SPIE, the Optical Society of America and the Institute of Physics. He was elected to Fellow of the Royal Society of Edinburgh in 2007 and is presently a Royal Society Wolfson Merit Award Holder.