1. Kirill V. Larin

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    1. Mentioned In 120 Articles

    2. Assessing mechanical properties of tissue phantoms with non-contact optical coherence elastography and Michelson interferometric vibrometry

      Assessing mechanical properties of tissue phantoms with non-contact optical coherence elastography and Michelson interferometric vibrometry
      Purpose : Elastography is an emerging method for detecting the pathological changes in tissue biomechanical properties caused by various diseases. In this study, we have compared two methods of noncontact optical elastography for quantifying Youngs modulus of tissue-mimicking agar phantoms of various concentrations: a laser Michelson interferometric vibrometer and a phase-stabilized swept source optical coherence elastography system. Methods : The elasticity of the phantoms was estimated from the velocity of air-pulse induced ...
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    3. Rotational imaging optical coherence tomography for full-body mouse embryonic imaging

      Rotational imaging optical coherence tomography for full-body mouse embryonic imaging
      Optical coherence tomography (OCT) has been widely used to study mammalian embryonic development with the advantages of high spatial and temporal resolutions and without the need for any contrast enhancement probes. However, the limited imaging depth of traditional OCT might prohibit visualization of the full embryonic body. To overcome this limitation, we have developed a new methodology to enhance the imaging range of OCT in embryonic day (E) 9.5 ...
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    4. Classifying murine glomerulonephritis using optical coherence tomography and optical coherence elastography

      Classifying murine glomerulonephritis using optical coherence tomography and optical coherence elastography
      Elastic-wave propagation in mouse healthy and nephritic kidneys. Acute glomerulonephritis caused by antiglomerular basement membrane marked by high mortality. The primary reason for this is delayed diagnosis via blood examination, urine analysis, tissue biopsy, or ultrasound and X-ray computed tomography imaging. Blood, urine, and tissue-based diagnoses can be time consuming, while ultrasound and CT imaging have relatively low spatial resolution, with reduced sensitivity. Optical coherence tomography is a noninvasive and ...
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    5. University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure of Fetal Brain Development

      University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure of Fetal Brain Development
      ...ce Tomography to Study Effect of Poly-Drug Exposure of Fetal Brain Development. The principal investigator is Kirill Larin. The program began in 2016 and ends in 2020. Below is a summary of the proposed work.

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    6. Direct four-dimensional structural and functional imaging of cardiovascular dynamics in mouse embryos with 1.5  MHz optical coherence tomography

      Direct four-dimensional structural and functional imaging of cardiovascular dynamics in mouse embryos with 1.5  MHz optical coherence tomography
      High-resolution three-dimensional (3D) imaging of cardiovascular dynamics in mouse embryos is greatly desired to study mammalian congenital cardiac defects. Here, we demonstrate direct four-dimensional (4D) imaging of the cardiovascular structure and function in live mouse embryos at a 43 Hz volume rate using an optical coherence tomography (OCT) system with a 1.5 MHz Fourier domain mode-locking swept laser source. Combining ultrafast OCT imaging with live mouse embryo culture protocols ...
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    7. Quantification of Mouse Embryonic Eye Development with Optical Coherence Tomography In Utero

      Quantification	of	Mouse	Embryonic	Eye	Development	with	 Optical	Coherence	Tomography	In	Utero
      Mouse models are commonly used as research tools to understand regulatory pathways affected by human diseases and disorders. Live imaging tools for visualization of mouse embryonic ocular tissues would be beneficial in research associated with developmental ocular defects. In this study, in utero quantitative assessment of ocular structures in mouse embryos was performed with a swept-source optical coherence tomography (SSOCT). To define developmental changes in eye morphology in live embryos ...
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    8. Feature Of The Week 03/22/15: Assessing Age-Related Changes in the Biomechanical Properties of Rabbit Lens using a Co-Focused Ultrasound and Optical Coherence Elastography System

      Feature Of The Week 03/22/15: Assessing Age-Related Changes in the Biomechanical Properties of Rabbit Lens using a Co-Focused Ultrasound and Optical Coherence Elastography System
      ...ical gradient of crystalline lens , Biomedical Optics Express 4.12 (2013): 2769-2780. Courtesy of Chen Wu and Kirill Larin and from University of Houston . Presbyopia, the progressive, age-related loss of accommodation p...
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    9. Comparison of optical projection tomography and optical coherence tomography for assessment of murine embryonic development

      Comparison of optical projection tomography and optical coherence tomography for assessment of murine embryonic development
      ... Nair ; Tegy Vadakkan ; Victor Piazza ; Ryan Udan ; Michael V. Frazier ; Trevor Janecek ; Mary E. Dickinson ; Kirill V. Larin; Comparison of optical projection tomography and optical coherence tomography for assessment o...
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    10. Live dynamic imaging and analysis of developmental cardiac defects in mouse models with optical coherence tomography

      Live dynamic imaging and analysis of developmental cardiac defects in mouse models with optical coherence tomography
      ...dels with optical coherence tomography Andrew L. Lopez ; Shang Wang ; Monica Garcia ; Christian Valladolid ; Kirill V. Larin ; Irina V. Larina; Live dynamic imaging and analysis of developmental cardiac defects in mouse...
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    11. Combined correlation estimation of axial displacement in optical coherence elastography: assessment of axial displacement sensitivity performance relative to existing methods

      Combined correlation estimation of axial displacement in optical coherence elastography: assessment of axial displacement sensitivity performance relative to existing methods
      ...t and gelatine phantom. A. Grimwood A. Messa, J. C. Bamber Optical Elastography and Tissue Biomechanics II Kirill V. Larin; David D. Sampson San Francisco, California, United States | February 07, 2015 A combined co...
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    12. 1-15 of 120 1 2 3 4 5 6 7 8 »
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  2. About Kirill V. Larin

    Kirill V. Larin

    Kirill V. Larin is Assistant Professor of Biomedical Engineering at the University of Houston, Houston, TX. His research interests focuses on development and application of OCT for noninvasive and nondestructive imaging and diagnostics of tissues and cells. Larin has authored more than 40 peer-reviewed journal publications and chapters in two textbooks on Biomedical Optics. He is recipient of Boris Yeltsin Presidential Award, Wallace Coulter Young Investigator Translation Award, Office of Naval Research Young Investigator Award, and Outstanding Young Investigator Award from the Houston Society for Engineers in Medicine and Biology.

  3. Quotes

    1. We are using OCT to image mouse and rat embryos, looking at video taken about seven days after conception, out of a 20-day typical mammalian pregnancy...this way, we are able to capture video of the embryonic heart before it begins beating, and a day later we can see the heart beginning to form in the shape of a tube and see whether or not the chambers are contracting. Then, we begin to see blood distribution and the heart rate.
      In The Embryonic Heart: Imaging Life as it Happens - University of Houston Professor Captures Video of Heart Before it Begins to Beat (Video Snippet)
    2. Our primary objective is to develop noninvasive, early detection methods to diagnose various diseases.
      In U. Houston professor expands Optics research