1. Kirill V. Larin

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    1. Mentioned In 115 Articles

    2. Quantification of Mouse Embryonic Eye Development with Optical Coherence Tomography In Utero

      Quantification	of	Mouse	Embryonic	Eye	Development	with	 Optical	Coherence	Tomography	In	Utero

      Mouse models are commonly used as research tools to understand regulatory pathways affected by human diseases and disorders. Live imaging tools for visualization of mouse embryonic ocular tissues would be beneficial in research associated with developmental ocular defects. In this study, in utero quantitative assessment of ocular structures in mouse embryos was performed with a swept-source optical coherence tomography (SSOCT). To define developmental changes in eye morphology in live embryos, the volume of the embryonic eye lens and the globe at different embryonic stages ranging from E13.5 to E18.5 was quantified. It is determined that the major axis ...

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    3. Feature Of The Week 03/22/15: Assessing Age-Related Changes in the Biomechanical Properties of Rabbit Lens using a Co-Focused Ultrasound and Optical Coherence Elastography System

      Feature Of The Week 03/22/15: Assessing Age-Related Changes in the Biomechanical Properties of Rabbit Lens using a Co-Focused Ultrasound and Optical Coherence Elastography System
      ...ical gradient of crystalline lens , Biomedical Optics Express 4.12 (2013): 2769-2780. Courtesy of Chen Wu and Kirill Larin and from University of Houston . Presbyopia, the progressive, age-related loss of accommodation p...
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    4. Comparison of optical projection tomography and optical coherence tomography for assessment of murine embryonic development

      Comparison of optical projection tomography and optical coherence tomography for assessment of murine embryonic development
      ... Nair ; Tegy Vadakkan ; Victor Piazza ; Ryan Udan ; Michael V. Frazier ; Trevor Janecek ; Mary E. Dickinson ; Kirill V. Larin; Comparison of optical projection tomography and optical coherence tomography for assessment o...
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    5. Live dynamic imaging and analysis of developmental cardiac defects in mouse models with optical coherence tomography

      Live dynamic imaging and analysis of developmental cardiac defects in mouse models with optical coherence tomography
      ...dels with optical coherence tomography Andrew L. Lopez ; Shang Wang ; Monica Garcia ; Christian Valladolid ; Kirill V. Larin ; Irina V. Larina; Live dynamic imaging and analysis of developmental cardiac defects in mouse...
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    6. Combined correlation estimation of axial displacement in optical coherence elastography: assessment of axial displacement sensitivity performance relative to existing methods

      Combined correlation estimation of axial displacement in optical coherence elastography: assessment of axial displacement sensitivity performance relative to existing methods
      ...t and gelatine phantom. A. Grimwood A. Messa, J. C. Bamber Optical Elastography and Tissue Biomechanics II Kirill V. Larin; David D. Sampson San Francisco, California, United States | February 07, 2015 A combined co...
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    7. Assessing Age-Related Changes in the Biomechanical Properties of Rabbit Lens Using a Coaligned Ultrasound and Optical Coherence Elastography System

      Assessing Age-Related Changes in the Biomechanical Properties of Rabbit Lens Using a Coaligned Ultrasound and Optical Coherence Elastography System
      ...eering, University of Miami College of Engineering, Coral Gables, Florida, United States 1. Correspondence: Kirill V. Larin, Department of Biomedical Engineering, University of Houston, 4800 Calhoun Road, 3605 Cullen B...
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    8. Algorithms for improved 3-D reconstruction of live mammalian embryo vasculature from optical coherence tomography data

      Algorithms for improved 3-D reconstruction of live mammalian embryo vasculature from optical coherence tomography data
      ..., USA; ^3Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA Correspondence to: Kirill V. Larin, PhD. Associate Professor, Department of Biomedical Engineering, University of Houston, 4800 C...
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    9. Quantitative assessment of corneal viscoelasticity using optical coherence elastography and a modified Rayleigh–Lamb equation

      Quantitative assessment of corneal viscoelasticity using optical coherence elastography and a modified Rayleigh–Lamb equation

      We demonstrate the use of a modified Rayleigh–Lamb frequency equation in conjunction with noncontact optical coherence elastography to quantify the viscoelastic properties of the cornea. Phase velocities of air-pulse-induced elastic waves were extracted by spectral analysis and used for calculating the Young’s moduli of the samples using the Rayleigh–Lamb frequency equation (RLFE). Validation experiments were performed on 2% agar phantoms ( n = 3 ) and then applied to porcine corneas ( n = 3 ) in situ . The Young’s moduli of the porcine corneas were estimated to be ∼ 60     kPa with a shear viscosity ∼ 0.33     Pa ⋅ s . The results demonstrate ...

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  2. About Kirill V. Larin

    Kirill V. Larin

    Kirill V. Larin is Assistant Professor of Biomedical Engineering at the University of Houston, Houston, TX. His research interests focuses on development and application of OCT for noninvasive and nondestructive imaging and diagnostics of tissues and cells. Larin has authored more than 40 peer-reviewed journal publications and chapters in two textbooks on Biomedical Optics. He is recipient of Boris Yeltsin Presidential Award, Wallace Coulter Young Investigator Translation Award, Office of Naval Research Young Investigator Award, and Outstanding Young Investigator Award from the Houston Society for Engineers in Medicine and Biology.

  3. Quotes

    1. We are using OCT to image mouse and rat embryos, looking at video taken about seven days after conception, out of a 20-day typical mammalian pregnancy...this way, we are able to capture video of the embryonic heart before it begins beating, and a day later we can see the heart beginning to form in the shape of a tube and see whether or not the chambers are contracting. Then, we begin to see blood distribution and the heart rate.
      In The Embryonic Heart: Imaging Life as it Happens - University of Houston Professor Captures Video of Heart Before it Begins to Beat (Video Snippet)
    2. Our primary objective is to develop noninvasive, early detection methods to diagnose various diseases.
      In U. Houston professor expands Optics research