1. Ki Hean Kim

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    1. Mentioned In 23 Articles

    2. Miniaturization of plastic lens by injection molding for disposable endoscopie optical coherence tomography system

      Miniaturization of plastic lens by injection molding for disposable endoscopie optical coherence tomography system
      Minimally invasive robotic surgery required disposable endoscopie optical coherence tomography (OCT) for high-resolution deep tissue imaging and cross-contamination prevention. Here, we developed a miniaturized plastic lens by injection molding for developing a disposable endoscopie optical coherence tomography system for the first time. Injection molding provided low-cost and high-production rate to produce a disposable plastic lens and enabled the miniaturization of plastic lens. Transmittance and curvature of the plastic lens was ...
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      Mentions: Ki Hean Kim
    3. In vivo visualization of skin inflammation by optical coherence tomography and two-photon microscopy

      In vivo visualization of skin inflammation by optical coherence tomography and two-photon microscopy
      Inflammation is a non-specific immune response to injury intended to protect biological tissue from harmful stimuli such as pathogens, irritants, and damaged cells. In vivo optical tissue imaging has been used to provide spatial and dynamic characteristics of inflammation within the tissue. In this paper, we report in vivo visualization of inflammation in the skin at both cellular and physiological levels by using a combination of label-free two-photon microscopy (TPM ...
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      Mentions: Ki Hean Kim
    4. Dark-field polarization-sensitive optical coherence tomography

      Dark-field polarization-sensitive optical coherence tomography
      Polarization-sensitive optical coherence tomography (PS-OCT) is a functional OCT providing both structural and birefringent information of the sample, and it has been applied to the studies of various organs having polarization properties. Fiber-based PS-OCT is sensitive to specular reflection from the sample surface, because signal saturation due to the strong specular reflection can make the polarization measurement difficult. We developed a dark-field PS-OCT which can avoid the specular reflection problem ...
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    5. In vivo wide-field reflectance/fluorescence imaging and polarization-sensitive optical coherence tomography of human oral cavity with a forward-viewing probe

      In vivo wide-field reflectance/fluorescence imaging and polarization-sensitive optical coherence tomography of human oral cavity with a forward-viewing probe
      We report multimodal imaging of human oral cavity in vivo based on simultaneous wide-field reflectance/fluorescence imaging and polarization-sensitive optical coherence tomography (PS-OCT) with a forward-viewing imaging probe. Wide-field reflectance/fluorescence imaging and PS-OCT were to provide both morphological and fluorescence information on the surface, and structural and birefringent information below the surface respectively. The forward-viewing probe was designed to access the oral cavity through the mouth with dimensions of ...
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    6. Combined two-photon microscopy and angiographic optical coherence tomography

      Combined two-photon microscopy and angiographic optical coherence tomography
      A combined two-photon microscopy (TPM) and angiographic optical coherence tomography (OCT) is developed, which can provide molecular, cellular, structural, and vascular information of tissue specimens in vivo . This combined system is implemented by adding an OCT vasculature visualization method to the previous combined TPM and OCT, and then is applied to in vivo tissue imaging. Two animal models, a mouse brain cranial window model and a mouse ear cancer model ...
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    7. In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography

      In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography
      The accurate determination of burn depth is critical in the clinical management of burn wounds. Polarization-sensitive optical coherence tomography (PS-OCT) has been proposed as a potentially non-invasive method for determining burn depth by measuring thermally induced changes in the structure and birefringence of skin, and has been investigated in pre-clinical burn studies with animal models and ex vivo human skin. In this study, we applied PS-OCT to the in-vivo imaging ...
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    8. Feature Of The Week 9/18/11: Combined Two-Photon Microscopy and Optical Coherence Tomography Using Individually Optimized Sources

      Feature Of The Week 9/18/11: Combined Two-Photon Microscopy and Optical Coherence Tomography Using Individually Optimized Sources
      Researchers from Phohang University of Science and Technology (POSTECH) in South Korea recent published an article on combined two-phton microscopy and optical coherence tomography using individually optimized sources. Below is a summary of that work.The combination of two-photon microscopy (TPM) and optical coherence tomography (OCT) is useful in conducting in-vivo tissue studies, because they provide complementary information regarding tissues. In the present study, we developed a new combined system ...
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    9. Polarization-Sensitive Optical Coherence Tomography Imaging of Benign and Malignant Laryngeal Lesions: An In Vivo Study

      Polarization-Sensitive Optical Coherence Tomography Imaging of Benign and Malignant Laryngeal Lesions: An In Vivo Study
      Objective. Optical coherence tomography (OCT), an imaging technology that provides cross-sectional subsurface tissue structure images using back-scattered light, is a promising noninvasive imaging modality for in vivo assessment of vocal fold layered microstructure. Polarization-sensitive OCT (PS-OCT) augments conventional OCT by detecting changes in the polarization state of reflected light. This study imaged various benign and malignant laryngeal pathologies in patients undergoing direct laryngoscopy under general anesthesia to determine whether PS-OCT ...
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    10. 1-15 of 23 1 2 »
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  2. About Ki Hean Kim

    Ki Hean Kim

    Ki Hean Kim received his B.S. and M.S. degrees in Mechanical Engineering from Seoul National University, Korea, in 1994 and 1996, respectively. He obtained Ph.D degree in Mechanical Engineering from MIT, USA, in 2005. After completion of his PhD, he moved to Wellman Center for Photomedicine, Massachusetts General Hospital, which is one of largest biomedical optics research centers. At MGH, he developed various optical coherence tomography (OCT) systems and probes, and did various preclinical and clinical studies such as mouse retinal imaging, human vocal fold imaging, and human burn imaging. He is currently an Assistant Professor of Mechanical Engineering and Integrative Biosciences and Biotechnology (IBB) at Pohang University of Science and Technology, Korea. His interests include advanced two-photon microscopy and OCT which can image tissue deeper and faster with better contrast, targeting both basic biological study such as immunology, neurology, cancer biology, and clinical diagnosis and therapy.