1. Kenya Nasu

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    1. Mentioned In 12 Articles

    2. In vivo tissue characterization of human atherosclerotic plaques by optical coherence tomography: A directional coronary atherectomy study with histopathologic confirmation

      In vivo tissue characterization of human atherosclerotic plaques by optical coherence tomography: A directional coronary atherectomy study with histopathologic confirmation
      Background The histopathological validation of optical coherence tomography (OCT) in visualizing atherosclerotic plaques has been reported only in ex vivo studies. We sought to evaluate the accuracy of OCT in tissue characterization in vivo . Methods and results A total of 25 patients with stable angina pectoris who underwent directional coronary atherectomy (DCA) were included in the investigation, whereby OCT was performed before and after a single debulking. The debulked region ...
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    3. Assessment of vascular response after drug-eluting stents implantation in patients with diabetes mellitus: an optical coherence tomography sub-study of the J-DESsERT

      Assessment of vascular response after drug-eluting stents implantation in patients with diabetes mellitus: an optical coherence tomography sub-study of the J-DESsERT
      Even in the drug-eluting stent era, diabetes mellitus (DM) patients have high incidences of restenosis and repeat revascularization after percutaneous coronary intervention. The aim of this study was to compare vascular response after stent implantation between sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) by using optical coherence tomography (OCT) in DM patients as well as in non-DM patients. In the Japan-Drug Eluting Stents Evaluation; a Randomized Trial (J-DESsERT), the OCT ...
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    4. Impact on Optical Coherence Tomographic Coronary Findings of Fluvastatin Alone versus Fluvastatin+ Ezetimibe

      Impact on Optical Coherence Tomographic Coronary Findings of Fluvastatin Alone versus Fluvastatin+ Ezetimibe
      Although lipid lowering therapy by statin and ezetimibe has been reported to provide greater reduction in low-density lipoprotein cholesterol (LDL-C) levels than statin monotherapy, the effect of supplemental therapy on plaque stabilization is yet to be fully elucidated. Cap thickness of fibroatheroma evaluated by Optical coherence tomography (OCT) is a major determinant of vulnerable plaque. The primary objective of this study is to evaluate the effect of ezetimibe in addition ...
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    5. Impact of Cholesterol Metabolism on Coronary Plaque Vulnerability of Target Vessels : A Combined Analysis of Virtual Histology Intravascular Ultrasound and Optical Coherence Tomography

      Impact of Cholesterol Metabolism on Coronary Plaque Vulnerability of Target Vessels : A Combined Analysis of Virtual Histology Intravascular Ultrasound and Optical Coherence Tomography
      Objectives The aim of this study was to evaluate the relationship between cholesterol metabolism and coronary plaque vulnerability. Background Cholesterol homeostasis, defined as the balance between absorption and synthesis, influences the progression of coronary atherosclerosis. Methods Consecutive stable angina pectoris patients (N = 80) not receiving any lipid-lowering therapy were divided into 2 groups based on the presence of in vivo thin cap fibroatheroma (TCFA) in de novo target vessels assessed ...
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    6. Response to Letter Regarding Article, "Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance"

      Response to Letter Regarding Article, "Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance"
      ...mal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance” 1. Maoto Habara, MD, 2. Kenya Nasu, MD and 3. Mitsuyasu Terashima, MD 1. Department of Cardiovascular Medicine, Toyohashi Heart Center...
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    7. Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance

      Impact of Frequency-Domain Optical Coherence Tomography Guidance for Optimal Coronary Stent Implantation in Comparison With Intravascular Ultrasound Guidance
      ...Y.A., O.K., T.S.); Okinaka Memorial Institute for Medical Research, Tokyo, Japan (H.K.). Correspondence to Dr Kenya Nasu, Toyohashi Heart Center, 21-1 Gobudori, Oyama-cho, Toyohashi 441–8530, Japan. E-mail Background—Fre...
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    8. Association of coronary plaque composition and arterial remodelling: A optical coherence tomography study - Corrected Proof

      Association of coronary plaque composition and arterial remodelling: A optical coherence tomography study - Corrected Proof
      Background Conflicting data have been reported about the association between plaque composition and remodelling index (RI). The aim of this study is to evaluate the relationship between plaque morphology obtained by optical coherence tomography (OCT) and arterial remodelling. Methods and results OCT and intravascular ultrasound imaging pull back was performed at corresponding sites on 94 lesions in 47 patients. OCT plaque characteristics for lipid content, fibrous cap thickness, thin-cap fibroatheroma ...
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    9. The impact of epicardial fat volume on coronary plaque vulnerability: insight from optical coherence tomography analysis

      The impact of epicardial fat volume on coronary plaque vulnerability: insight from optical coherence tomography analysis
      Aims Epicardial fat volume (EFV) has been implicated in coronary artery disease. Relationship between EFV and coronary plaque vulnerability has not been elucidated. The aim of this study was to investigate the association of EFV with coronary plaque vulnerability by using optical coherence tomography (OCT). Methods and results We enrolled 117 patients who underwent multislice computed tomography (MSCT) and OCT. EFV was quantified on MSCT. Patients were categorized according to ...
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    10. Feature Of The Week 6/5/11: Researchers from Toyohashi Heart Center Compare Multislice Computed Tomography and Optical Coherence Tomography for In-Vivo Assessment of Vulnerable Plaque

      Feature Of The Week 6/5/11: Researchers from Toyohashi Heart Center Compare Multislice Computed Tomography and Optical Coherence Tomography for In-Vivo Assessment of Vulnerable Plaque
      Cardiovascular disease is one of the major causes of death in the world. One component of this deadly disease is the rupture or thin walled unstable plaques. Increased detection of rupture-prone vulnerable plaque could be promising for better risk stratification of patients. Intravascular OCT has emerged as one of the most promising techniques for non-ionizing, high-resolution, in-vivo plaque characterization and assessment. However OCT is still an (minimally) invasive procedure. Multislice ...
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    11. Difference of Tissue Characteristics Between Early and Very Late Restenosis Lesions After Bare-Metal Stent Implantation: An Optical Coherence Tomography Study

      Difference of Tissue Characteristics Between Early and Very Late Restenosis Lesions After Bare-Metal Stent Implantation: An Optical Coherence Tomography Study
      Background—Although in-stent restenosis (ISR) after bare-metal stent (BMS) implantation peaks in the early phase, very late (VL) ISR occasionally is observed beyond a few years after BMS implantation. To date, this mechanism has not been fully clarified. Methods and Results—We compared the morphological characteristics of VL-ISR (>5 years, without restenosis within the first year) (n=43) to those of early (E) ISR (within the first year) (n=39 ...
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    12. Comparison of Subsequent Vascular Response in Diabetic Patients Following Coronary Stenting Between Sirolimus- and Paclitaxel-Eluting Stents: Optical Coherence Tomography Analysis

      Comparison of Subsequent Vascular Response in Diabetic Patients Following Coronary Stenting Between Sirolimus- and Paclitaxel-Eluting Stents: Optical Coherence Tomography Analysis
      ...equent vascular response after PES implantation in DM group was similar to that in non DM group. OCT findings Kenya Nasu; Mitsuyasu Terashima; Etsuo Tsuchikane; Osamu Katoh; Takahiko Suzuki Toyohashi Heart Cntr, Toyohash...
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    13. Difference in Neointimal Growth on the Stent Struts Crossing a Side Branch Between Sirolimus-Eluting Stent and Bare-Metal Stent: An Optical Coherence Tomography Analysis

      Difference in Neointimal Growth on the Stent Struts Crossing a Side Branch Between Sirolimus-Eluting Stent and Bare-Metal Stent: An Optical Coherence Tomography Analysis
      ...a^; Hitoshi Matsuo^; Keiko Asakura^; Etsuo Tsuchikane^; Mariko Ehara^; Yoshihisa Kinoshita^; Masashi Kimura^; Kenya Nasu^; Osamu Katoh^; Takahiko Suzuki^ Toyohashi Heart Cntr, Toyohashi, Japan Background: A bifurcation l...
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  2. About Kenya Nasu

    Kenya Nasu

    Kenya Nasu is a cardiologist at the Toyohashi Heart Center in Japan.