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1. Mentioned In 39 Articles
2. Predictors of Rapid Plaque Progression: An Optical Coherence Tomography Study
  
  Explore ScienceDirect Oct 6 2020 Cardiology
  
  Objectives This study sought to identify morphological predictors of rapid plaque progression. Background Two patterns of plaque progression have been described: slow linear progression and rapid step-wise progression. The former pattern will cause stable angina when the narrowing reaches a critical threshold, whereas the latter pattern may lead to acute coronary syndromes or sudden cardiac death. Methods Patients who underwent optical coherence tomography (OCT) imaging during the index procedure and ...
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  Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University
3. Prevalence and Clinical Significance of Layered Plaque in Patients With Stable Angina Pectoris ― Evaluation With Histopathology and Optical Coherence Tomography ―
  
  Explore jstage.jst.go.jp Oct 24 2019 Cardiology
  
  Background: Healed plaques are identified as a layered pattern with optical coherence tomography (OCT) imaging, but the exact relationship between healed plaques and the development of significant coronary stenosis in stable angina pectoris (SAP) is not fully understood. Methods and Results: A retrospective clinincal study investigated the OCT characteristics of culprit lesions of SAP patients (n=205), and a prospective study examined the histopathological characteristics of layered plaque in directional ...
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  Mentions: Kawasaki Medical School Shiro Uemura Teruyoshi Kume
4. Foveal avascular zone and macular vessel density after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography
  
  Explore BMC Ophthalmology Aug 10 2019 Ophthalmology
  
  Background To investigate the area of foveal avascular zone (FAZ) and macular vessel density (VD) after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography (OCTA). Methods Participants comprised 15 patients with unilateral amblyopia due to anisometropia with or without strabismus (mean age, 9.83.4years; range, 617years). OCTA images were obtained by using spectral-domain OCT with angiography software. The OCTA scanning protocol used was 33-mm volume ...
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  Mentions: National Institutes of Health Kawasaki Medical School
5. Successful Treatment of Genital Warts with Ingenol Mebutate Monitored with Optical Coherence Tomography and Reflectance Confocal Microscopy
  
  Explore KoreaMed Synapse Jul 16 2019 Dermatology
  
  Ingenol mebutate (IM) is approved for the treatment of actinic keratosis and induces cell death in precancerous lesions. The efficacy of IM in the treatment of genital warts was investigated in a therapy-refractory patient. The 74-year-old male was treated with IM gel for three consecutive days. Treatment course and efficacy were evaluated by clinical inspection and non-invasive diagnostics namely optical coherence tomography (OCT) and reflectance confocal microscopy (RCM). Within 24 ...
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  Mentions: Kawasaki Medical School
6. Healed Culprit Plaques in Patients With Acute Coronary Syndrome
  
  Explore onlinejacc.org May 9 2019 Cardiology
  
  ackground Healed plaques, morphologically characterized by a layered phenotype, are frequently found in subjects with sudden cardiac death. However, in vivo data are lacking. Objectives The purpose of this study was to determine the prevalence, morphological characteristics, and clinical significance of healed culprit plaques in patients with acute coronary syndromes (ACS) using optical coherence tomography (OCT). Methods A total of 376 ACS patients (252 ST-segment elevation myocardial infarction [MI] and ...
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  Mentions: Massachusetts Institute of Technology James G. Fujimoto Mount Sinai School of Medicine
7. Usefulness of longitudinal reconstructed optical coherence tomography images for predicting the need for the reverse wire technique during coronary bifurcation interventions
  
  Explore Wiley Online Library Nov 25 2018 Cardiology
  
  Objectives The aim is to investigate the usefulness of longitudinal reconstructed optical coherence tomography (OCT) images in selecting the reverse wire (RW) technique for inserting a guidewire into a side branch (SB). Background It is sometimes necessary to protect the SB with a guidewire to prevent SB complications in PCI for bifurcation lesions. The RW is a novel method for guidewire insertion into an extremely angulated SB when the standard ...
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  Mentions: Kawasaki Medical School Tsunenari Soeda Yoshihiko Saito
8. Neointimal coverage of jailed side branches in coronary bifurcation lesions: an optical coherence tomography analysis
  
  Explore LWW Online Sep 20 2017 Cardiology
  
  Objectives: The jailed strut at the side-branch (SB) orifice may be a cause of delayed neointimal coverage and SB flow disturbance after single stenting to bifurcation. The aim of this study was to characterize the exact relationship between the jailed strut pattern at the SB orifice immediately after stent implantation and neointimal coverage of the jailed SB orifice in the chronic phase. Patients and methods: A total of 29 bifurcation ...
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  Mentions: Kawasaki Medical School Shiro Uemura Yoji Neishi
9. Current clinical applications of coronary optical coherence tomography
  
  Explore Home - Springer Jul 20 2017 Cardiology
  
  Optical coherence tomography (OCT) is an intra-coronary diagnostic technique that provides detailed imagings of blood vessels in the current cardiac catheterization laboratory. The higher resolution of OCT often provides superior delineation of each structure compared with intravascular ultrasound (IVUS), and it can reliably visualize the microstructure of normal and diseased arteries. The capabilities of OCT are well suited for the identification of calcified plaque and neointima formation after stent implantation ...
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  Mentions: Kawasaki Medical School Shiro Uemura Teruyoshi Kume
10. Quantitative Analysis of Macular Inner Retinal Layer Using Swept-Source Optical Coherence Tomography in Patients with Optic Tract Syndrome
  
  Explore Hindawi Publishing Corporation Jul 5 2017 Ophthalmology
  
  Objective . To evaluate macular inner retinal layers using swept-source optical coherence tomography (SS-OCT) in patients with homonymous hemianopia due to optic tract syndrome (OTS). Methods . Sixteen eyes of 8 patients with OTS were studied. The macular retinal nerve fiber layer (mRNFL), ganglion cell layer and inner plexiform layer (GCL+IPL), and mRNFL and GCL+IPL (GCC) were measured by SS-OCT (DRI OCT-1 Atlantis).The scanned area was divided into eight ...
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  Mentions: Kawasaki Medical School
11. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study
  
  Explore ScienceDirect May 29 2017 Cardiology
  
  Background Lipid-rich plaque (LRP) is thought to be a precursor to cardiac events. However, its clinical significance in coronary arteries has never been systematically investigated. Objectives This study investigated the prevalence and clinical significance of LRP in the nonculprit region of the target vessel in patients undergoing percutaneous coronary intervention (PCI). Methods The study included 1,474 patients from 20 sites across 6 countries undergoing PCI, who had optical coherence ...
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  Mentions: University of Pittsburgh Massachusetts Institute of Technology James G. Fujimoto
12. Two-year vascular responses to drug-eluting stents with biodegradable polymer versus durable polymer: An optical coherence tomography sub-study of the NEXT
  
  Explore Journal of Cardiology May 28 2017 Cardiology
  
  Background This study aimed to compare very late vascular response after stent implantation between everolimus-eluting stent (EES) with a thin, non-adhesive, durable, biocompatible fluorinated polymer and biolimus-eluting stent (BES) with a biodegradable polymer by optical coherence tomography (OCT). Methods and results In the NOBORI-BES Versus XIENCE V/PROMUS-EES Trial (NEXT), a formal OCT substudy investigated 48 patients (27 EES-treated lesions in 23 patients and 28 BES-treated lesions in 25 patients ...
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  Mentions: Takashi Kubo Takashi Akasaka Kawasaki Medical School
13. Impact of branching angle on neointimal coverage of drug-eluting stents implanted in bifurcation lesions
  
  Explore LWW Online Nov 24 2016 Cardiology
  
  Objectives: To investigate the impact of branching angle (BA) on neointimal coverage of drug-eluting stents (DESs) in bifurcation lesions. Background: Previous experimental studies indicated that BA influences the local flow turbulence and wall shear stress, which are associated with neointimal coverage of DESs. Methods: Fifty-five bifurcation lesions in 47 patients were evaluated by serial optical coherence tomography (OCT) before DES implantation and at follow-up. Neointimal coverage was assessed in cross-sectional ...
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  Mentions: Kawasaki Medical School Satoshi Okayama Tsunenari Soeda
14. Impact of stent platform on longitudinal stent deformation: an in vivo frequency domain optical coherence tomography study
  
  Explore Home - Springer May 27 2016 Cardiology
  
  Recently, longitudinal coronary stent deformation has been highlighted as a possible cause of drug-eluting stent failure. Although bench tests and in vivo studies have demonstrated difference in longitudinal stent strength among the stents with different platforms, its clinical impact is still unknown. Furthermore, it is unknown if modified stent platform favorably affect the incidence of stent deformation. The aim of this study was to investigate the longitudinal deformation of the ...
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  Mentions: Kawasaki Medical School Shiro Uemura Teruyoshi Kume
15. Thin-cap fibroatheroma and large calcification at the proximal stent edge correlate with a high proportion of uncovered stent struts in the chronic phase
  
  Explore LWW Online May 14 2016 Cardiology
  
  Objective: A high proportion of uncovered stent struts is associated with late stent thrombosis after drug-eluting stent (DES) implantation, which frequently results in myocardial infarction or death. However, the predictors of uncovered stent struts remain unknown. Here, using optical coherence tomography (OCT), we studied the baseline tissue characteristics of the target coronary segment and evaluated their influence on the neointimal coverage of the strut in the chronic phase. Methods: We ...
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  Mentions: Kawasaki Medical School Hiroyuki Kawata Satoshi Okayama
16. High Platelet Reactivity and Intrastent Thrombi Assessed by OCT After DES
  
  Explore imaging.onlinejacc.org Apr 21 2016 Cardiology
  
  High platelet reactivity (HPR) on clopidogrel may be related to stent thrombosis after drug-eluting stent (DES) implantation (1) . To investigate the relationship between HPR and intrastent thrombi following DES implantation, 202 lesions treated with DES from 109 patients were studied. Coronary angiography and optical coherence tomography (OCT) examination were performed as parts of routine follow-up examination at our institution except for the presence of renal dysfunction or congestive heart failure ...
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  Mentions: Kawasaki Medical School Shiro Uemura Hiroyuki Okura
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