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1. Mentioned In 46 Articles
2. Case report: Corneal endothelial degeneration and optic atrophy in dentatorubral-pallidoluysian atrophy quantified by specular micrography and optical coherence tomography
  
  Explore Frontiers Oct 1 2022 Ophthalmology
  
  Introduction: Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant neurodegenerative disease with various neurological manifestations. Corneal endothelial degeneration and optic atrophy have been reported separately; however, there are no reports of corneal endothelial degeneration with optic atrophy. Cases: Herein, we present four related patients with DRPLA: two patients (69-year-old woman and 80-year-old man) who exhibited both corneal endothelial degeneration and optic atrophy and another two (49- and 51-year-old women, respectively) who ...
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  Mentions: Kawasaki Medical School
3. The role of basal sweating in maintaining skin hydration in the finger: a long-standing paradox in dry skin resolved
  
  Explore Wiley Online Library Sep 3 2022 Dermatology
  
  long-standing paradox in dermatology is why skin dehydration in the fingers can be triggered by repeated water exposure despite the action of water to hydrate skin tissue. Potential clues might be provided by identifying a mechanism through which water is held in the skin of the fingers. We speculated that this mechanism would be impaired after repeated water exposure. Here, we investigated whether there might be glabrous skin-specific water-holding machinery ...
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  Mentions: Kawasaki Medical School
4. Optical coherence tomography in coronary atherosclerosis assessment and intervention
  
  Explore Nature Publishing Group Apr 30 2022 Cardiology
  
  Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in ...
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  Mentions: Brigham and Women’s Hospital Johns Hopkins University Massachusetts Institute of Technology
5. Layered Plaque in Organic Lesions in Patients With Coronary Artery Spasm
  
  Explore Home | AHA/ASA Journals Mar 25 2022 Cardiology
  
  Background Coronary artery spasm plays a vital role in the pathogenesis of coronary plaques. We sought to investigate the plaque characteristics of co‐existing organic lesions in patients with coronary artery spasm in comparison to those without coronary artery spasm by intracoronary optical coherence tomography (OCT). Methods and Results We included 39 patients who presented with a symptom suspected of coronary spastic angina and had an organic lesion, defined as ...
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  Mentions: Kawasaki Medical School
6. Head-to-head comparison of quantitative measurements between intravascular imaging systems: An in vitro phantom study
  
  Explore ScienceDirect Sep 11 2021 Cardiology
  
  Introduction The present study aimed to compare the accuracy of quantitative measurements by contemporary intravascular imaging systems including optical frequency domain imaging (OFDI), frequency domain optical coherence tomography (FD-OCT), and 6 intravascular ultrasound (IVUS) systems. Methods We imaged five cylindrical phantom models made from an acrylic resin with known lumen diameters (1.51, 2.03, 3.04, 4.04, and 5.04 mm, respectively) using OFDI (FastView and LUNAWAVE, Terumo ...
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  Mentions: Terumo Corporation Stanford University Abbott
7. Acute coronary syndrome demonstrating plaque rupture in calcified plaque visualized by optical coherence tomography and near-infrared spectroscopy combined with intravascular ultrasound
  
  Explore ScienceDirect May 15 2021 Cardiology
  
  Optical coherence tomography (OCT) can visualize calcification of the coronary plaque as a low-intensity lesion with sharp borders. However, residual lipid tissue inside the calcification could pose a problem in plaque evaluation by OCT. We present a case of acute coronary syndrome (ACS) demonstrating plaque rupture in the calcified plaque. In this case, OCT demonstrated a cavity suspected to represent rupture in the calcified plaque and near-infrared spectroscopy revealed a ...
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  Mentions: Kawasaki Medical School
8. Choroidal vessel density in unilateral hyperopic amblyopia using en-face optical coherence tomography
  
  Explore BMC Ophthalmology Dec 4 2020 Ophthalmology
  
  Background: Structural changes of the choroid, such as choroidal thickening, have been indicated in amblyopic eyes with hyperopic anisometropia as compared to fellow or healthy eyes. The purpose of the present study was to investigate choroidal vascular density (CVD) in children with unilateral hyperopic amblyopia. Methods: This study included 88 eyes of 44 patients with unilateral amblyopia due to hyperopic anisometropia with or without strabismus and 29 eyes of 29 ...
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  Mentions: Kawasaki Medical School
9. Predictors of Rapid Plaque Progression: An Optical Coherence Tomography Study
  
  Explore ScienceDirect Oct 6 2020 Cardiology
  
  Objectives This study sought to identify morphological predictors of rapid plaque progression. Background Two patterns of plaque progression have been described: slow linear progression and rapid step-wise progression. The former pattern will cause stable angina when the narrowing reaches a critical threshold, whereas the latter pattern may lead to acute coronary syndromes or sudden cardiac death. Methods Patients who underwent optical coherence tomography (OCT) imaging during the index procedure and ...
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  Mentions: Massachusetts General Hospital Harvard University Kawasaki Medical School
10. Prevalence and Clinical Significance of Layered Plaque in Patients With Stable Angina Pectoris ― Evaluation With Histopathology and Optical Coherence Tomography ―
  
  Explore jstage.jst.go.jp Oct 24 2019 Cardiology
  
  Background: Healed plaques are identified as a layered pattern with optical coherence tomography (OCT) imaging, but the exact relationship between healed plaques and the development of significant coronary stenosis in stable angina pectoris (SAP) is not fully understood. Methods and Results: A retrospective clinincal study investigated the OCT characteristics of culprit lesions of SAP patients (n=205), and a prospective study examined the histopathological characteristics of layered plaque in directional ...
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  Mentions: Kawasaki Medical School
11. Foveal avascular zone and macular vessel density after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography
  
  Explore BMC Ophthalmology Aug 10 2019 Ophthalmology
  
  Background To investigate the area of foveal avascular zone (FAZ) and macular vessel density (VD) after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography (OCTA). Methods Participants comprised 15 patients with unilateral amblyopia due to anisometropia with or without strabismus (mean age, 9.83.4years; range, 617years). OCTA images were obtained by using spectral-domain OCT with angiography software. The OCTA scanning protocol used was 33-mm volume ...
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  Mentions: National Institutes of Health Kawasaki Medical School
12. Successful Treatment of Genital Warts with Ingenol Mebutate Monitored with Optical Coherence Tomography and Reflectance Confocal Microscopy
  
  Explore KoreaMed Synapse Jul 16 2019 Dermatology
  
  Ingenol mebutate (IM) is approved for the treatment of actinic keratosis and induces cell death in precancerous lesions. The efficacy of IM in the treatment of genital warts was investigated in a therapy-refractory patient. The 74-year-old male was treated with IM gel for three consecutive days. Treatment course and efficacy were evaluated by clinical inspection and non-invasive diagnostics namely optical coherence tomography (OCT) and reflectance confocal microscopy (RCM). Within 24 ...
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  Mentions: Kawasaki Medical School
13. Healed Culprit Plaques in Patients With Acute Coronary Syndrome
  
  Explore onlinejacc.org May 9 2019 Cardiology
  
  ackground Healed plaques, morphologically characterized by a layered phenotype, are frequently found in subjects with sudden cardiac death. However, in vivo data are lacking. Objectives The purpose of this study was to determine the prevalence, morphological characteristics, and clinical significance of healed culprit plaques in patients with acute coronary syndromes (ACS) using optical coherence tomography (OCT). Methods A total of 376 ACS patients (252 ST-segment elevation myocardial infarction [MI] and ...
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  Mentions: Massachusetts Institute of Technology Mount Sinai School of Medicine Massachusetts General Hospital
14. Usefulness of longitudinal reconstructed optical coherence tomography images for predicting the need for the reverse wire technique during coronary bifurcation interventions
  
  Explore Wiley Online Library Nov 25 2018 Cardiology
  
  Objectives The aim is to investigate the usefulness of longitudinal reconstructed optical coherence tomography (OCT) images in selecting the reverse wire (RW) technique for inserting a guidewire into a side branch (SB). Background It is sometimes necessary to protect the SB with a guidewire to prevent SB complications in PCI for bifurcation lesions. The RW is a novel method for guidewire insertion into an extremely angulated SB when the standard ...
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  Mentions: Kawasaki Medical School Nara Medical University
15. Neointimal coverage of jailed side branches in coronary bifurcation lesions: an optical coherence tomography analysis
  
  Explore LWW Online Sep 20 2017 Cardiology
  
  Objectives: The jailed strut at the side-branch (SB) orifice may be a cause of delayed neointimal coverage and SB flow disturbance after single stenting to bifurcation. The aim of this study was to characterize the exact relationship between the jailed strut pattern at the SB orifice immediately after stent implantation and neointimal coverage of the jailed SB orifice in the chronic phase. Patients and methods: A total of 29 bifurcation ...
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  Mentions: Kawasaki Medical School Nara Medical University
16. Current clinical applications of coronary optical coherence tomography
  
  Explore Home - Springer Jul 20 2017 Cardiology
  
  Optical coherence tomography (OCT) is an intra-coronary diagnostic technique that provides detailed imagings of blood vessels in the current cardiac catheterization laboratory. The higher resolution of OCT often provides superior delineation of each structure compared with intravascular ultrasound (IVUS), and it can reliably visualize the microstructure of normal and diseased arteries. The capabilities of OCT are well suited for the identification of calcified plaque and neointima formation after stent implantation ...
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  Mentions: Kawasaki Medical School
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