1. Kate Grieve

    0 Comments Leave a Comment

    1-15 of 32 1 2 »
    1. Mentioned In 32 Articles

    2. Adaptive-glasses time-domain FFOCT for wide-field high-resolution retinal imaging with increased SNR

      Adaptive-glasses time-domain FFOCT for wide-field high-resolution retinal imaging with increased SNR
      The highest three-dimensional (3D) resolution possible in in vivo retinal imaging is achieved by combining optical coherence tomography (OCT) and adaptive optics. However, this combination brings important limitations, such as small field-of-view and complex, cumbersome systems, preventing so far the translation of this technology from the research lab to clinics. In this Letter, we mitigate these limitations by combining our compact time-domain full-field OCT (FFOCT) with a multi-actuator adaptive lens ...
      Read Full Article
    3. Coherence gate shaping for wide field high-resolution in vivo retinal imaging with full-field OCT

      Coherence gate shaping for wide field high-resolution in vivo retinal imaging with full-field OCT
      Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but it is particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is normally achieved with adaptive optics (AO) and scanning methods, which considerably reduce the useful FOV and increase the system complexity. An alternative technique is time-domain full-field optical coherence tomography (FF-OCT), which has already shown ...
      Read Full Article
    4. i2Eye Meeting 2020 - Webinar October 12-14, 2020

      i2Eye Meeting 2020 - Webinar October 12-14, 2020
      12 - 14 October 2020 We are proud to announce our 3rd annual multidisciplinary conference, this year as a webinar, entitled "i2eye Innovative Imaging in Eye Disease", on 12-14 October. Speakers and attendees are a mix of physicists, biologists and ophthalmologists interested in specific medical issues related to ocular imaging. This is a unique opportunity to combine fields of knowledge for a better understanding of diseases and ultimately for better clinical ...
      Read Full Article
      Mentions: Kate Grieve
    5. Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids

      Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids
      Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue but lacks functional information. We present dynamic full-field optical coherence tomography as a technique to noninvasively image living human induced pluripotent stem cell-derived retinal organoids. Coloured images with an endogenous contrast linked to organelle motility are generated, with submicrometre spatial resolution and millisecond temporal resolution, creating a way to identify specific cell types in living tissue ...
      Read Full Article
    6. Optical Incoherence Tomography: a method to generate tomographic retinal cross-sections with non-interferometric imaging systems

      Optical Incoherence Tomography: a method to generate tomographic retinal cross-sections with non-interferometric imaging systems
      Optical tomographic cross-sectional images of biological samples were made possible by interferometric imaging techniques such as Optical Coherence Tomography (OCT) [1, 2, 3]. Owing to its unprecedented view of the sample, OCT has become a gold standard, namely for human retinal imaging in the clinical environment. In this Letter, we present Optical Incoherence Tomography (OIT): a completely digital method extending the possibility to generate tomographic retinal cross-sections to non-interferometric imaging ...
      Read Full Article
    7. Multimodal Imaging Features of Schnyder Corneal Dystrophy

      Multimodal Imaging Features of Schnyder Corneal Dystrophy
      Objective. To describe the multimodal imaging of Schnyder corneal dystrophy.Methods. Seven eyes of seven patients (5 female and 2 male patients) aged 52 to 92 years were included in this prospective observational study. Diagnosis of SCD was confirmed by histology after keratoplasty. In vivo multimodal imaging consisted of spectral domain-optical coherence tomography with cross sections, en face scans, corneal pachymetry, and epithelial mapping, and in vivo confocal microscopy was ...
      Read Full Article
    8. Real-time, non-contact, cellular imaging and angiography of human cornea and limbus with common-path Full-field/SD OCT

      Real-time, non-contact, cellular imaging and angiography of human cornea and limbus with common-path Full-field/SD OCT
      In todays clinics, a cellular-resolution view of the cornea can be achieved only with an in vivo confocal microscope (IVCM) in contact with the eye. Here, we present a common-path Full-field/Spectral-domain OCT microscope (FF/SD OCT), which, for the first time, enables cell-detail imaging of the entire ocular surface (central and peripheral cornea, limbus, sclera, tear film) without contact and in real time. The device, that has been successfully ...
      Read Full Article
    9. Curved-Full-Field OCT for high-resolution imaging of living human retina over a large field-of-view

      Curved-Full-Field OCT for high-resolution imaging of living human retina over a large field-of-view
      Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine [1, 2, 3], but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is normally achieved with adaptive optics (AO) and scanning methods, which considerably reduce the useful FOV and increase the system complexity. An alternative technique is time-domain Full-Field Optical Coherence Tomography (FF-OCT) [4, 5], which ...
      Read Full Article
    10. ATTENUATION OUTER RETINAL BANDS ON OPTICAL COHERENCE TOMOGRAPHY FOLLOWING MACULAR EDEMA: A Possible Manifestation of Photoreceptor Misalignmen

      ATTENUATION OUTER RETINAL BANDS ON OPTICAL COHERENCE TOMOGRAPHY FOLLOWING MACULAR EDEMA: A Possible Manifestation of Photoreceptor Misalignmen
      Purpose: Macular edema is a common retinal disease which may leave important anatomical and functional sequelaes. Directional fundus imaging consists of comparing on- and off-axis images to reveal angle-dependent reflectance properties of fundus structures, which may be related to misaligned photoreceptors . Here, we analyzed directional optical coherence tomography (OCT) and flood-illumination adaptive optics ophthalmoscopy images to detect evidence of misaligned photoreceptors following macular edema . Methods: Transversal, observational study. Nine patients ...
      Read Full Article
    11. Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids

      Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids
      Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue, but lacks functional information. We present dynamic full-field optical coherence tomography to image living human induced pluripotent stem cell-derived retinal organoids non-invasively. Colored images with an endogenous contrast linked to organelle motility are generated, with sub-micrometer spatial resolution and millisecond temporal resolution, opening an avenue to identify specific cell types in living tissue via their function.
      Read Full Article
    12. Highlighting Directional Reflectance Properties of Retinal Substructures From D-OCT Images

      Highlighting Directional Reflectance Properties of Retinal Substructures From D-OCT Images
      Optical coherence tomography (OCT), which is routinely used in ophthalmology, enables transverse optical imaging of the retina and, hence, the identification of the different neuronal layers. Directional OCT (D-OCT) extends this technology by acquiring sets of images at different incidence angles of the light beam. In this way, reflectance properties of photoreceptor substructures are highlighted, enabling physicians to study their orientation, which is potentially an interesting biomarker for retinal diseases ...
      Read Full Article
    13. Probing dynamic processes in the eye at multiple spatial and temporal scales with multimodal full field OCT

      Probing dynamic processes in the eye at multiple spatial and temporal scales with multimodal full field OCT
      We describe recent technological progress in multimodal en face full-field optical coherence tomography that has allowed detection of slow and fast dynamic processes in the eye. We show that by combining static, dynamic and fluorescence contrasts we can achieve label-free high-resolution imaging of the retina and anterior eye with temporal resolution from milliseconds to several hours, allowing us to probe biological activity at subcellular scales inside 3D bulk tissue. Our ...
      Read Full Article
    14. 1-15 of 32 1 2 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Kate Grieve

    Kate Grieve

    Kate Grieve is based at Institut Langevin (ESPCI, Paris) and works closely with LLTech, the start-up company offering commercial full-field OCT systems for the pathology lab. She has worked in the field of optical techniques for medical imaging since completing her PhD on the development of full-field OCT in 2005.