1. Karol Karnowski

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    1. Mentioned In 25 Articles

    2. Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography

      Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography
      We employ optical coherence tomography (OCT) and optical coherence microscopy (OCM) to study conjunctival lymphatics in porcine eyes ex vivo . This study is a precursor to the development of in vivo imaging of the collecting lymphatics for potentially guiding and monitoring glaucoma filtration surgery. OCT scans at 1300 nm and higher‐resolution OCM scans at 785 nm reveal the lymphatic vessels via their optical transparency. Equivalent signal characteristics are also ...
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    3. A study of the effects of supine position and fluid intake on normal airway geometry using anatomical optical coherence tomography

      A study of the effects of supine position and fluid intake on normal airway geometry using anatomical optical coherence tomography
      Airway inhalation injuries are present in up to a third of all major burns patients and are the leading cause of mortality among this population. Understanding the mechanism of injury could minimise oedema (swelling) and airway damage. In this study, we present an anatomical OCT (aOCT) imaging system, based on a 1300-nm wavelength, high-speed, long-range MEMS-VCSEL swept laser source, for real-time volumetric imaging and assessment of inhalation injuries in airways ...
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    4. Swept source optical coherence tomography and tunable lens technology for comprehensive imaging and biometry of the whole eye

      Swept source optical coherence tomography and tunable lens technology for comprehensive imaging and biometry of the whole eye
      Standard optical systems in ophthalmology are strictly dedicated either to retinal or to anterior segment imaging due to the refractive properties of the eye. We demonstrate a swept source optical coherence tomography platform with an electrically tunable lens (ETL) for versatile 3D in vivo imaging of both the eyes anterior segment and the retina. The optimized optical setup with adaptive operational states of the ETL permits focusing on the retina ...
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    5. New instrument lets doctors view the entire eye with unprecedented level of detail

      New instrument lets doctors view the entire eye with unprecedented level of detail
      Researchers have developed the first instrument that can provide a detailed image of the entire eye. By incorporating a lens that changes optical parameters in response to an electric current, the innovative technology can produce higher quality images than currently available and could make eye examinations faster and more comfortable for patients by avoiding the need to undergo imaging with multiple instruments to look at different areas of the eye ...
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    6. Research Associate / Research Fellow Microscope-in-a-Needle at the University of Western Australia

      Research Associate / Research Fellow Microscope-in-a-Needle at the University of Western Australia
      Job no: 499437 Work type: full-time Location: Crawley Categories: Health and Medical Sciences, Engineering and Mathematical Sciences 1 year appointment Salary range: Level A $67,352 - $91,397 p.a. or Level B $96,210 - $114,250 p.a. (dependent on qualifications and experience) Research Development In Biomedical Photonics/Optical Microscopy (Australia) The University of Western Australia (UWA) is ranked amongst the top Australian universities and a member of the ...
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    7. Feature Of The Week 10/08/2017: Optical Coherence Microscopy as a Novel, Non-Invasive Method for the 4D Live Imaging of Early Mammalian Embryos

      Feature Of The Week 10/08/2017: Optical Coherence Microscopy as a Novel, Non-Invasive Method for the 4D Live Imaging of Early Mammalian Embryos
      ...apter in imaging-based preimplantation embryo diagnostics. For more information see recent Article . Courtesy Karol Karnowski from Nicolaus Copernicus University . Imaging of living cells based on traditional fluorescenc...
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    8. Optical coherence microscopy as a novel, non-invasive method for the 4D live imaging of early mammalian embryos

      Optical coherence microscopy as a novel, non-invasive method for the 4D live imaging of early mammalian embryos
      Imaging of living cells based on traditional fluorescence and confocal laser scanning microscopy has delivered an enormous amount of information critical for understanding biological processes in single cells. However, the requirement for a high numerical aperture and fluorescent markers still limits researchers ability to visualize the cellular architecture without causing short- and long-term photodamage. Optical coherence microscopy (OCM) is a promising alternative that circumvents the technical limitations of fluorescence imaging ...
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    9. Non-contact investigation of the corneal biomechanics with air-puff swept source optical coherence tomography

      Non-contact investigation of the corneal biomechanics with air-puff swept source optical coherence tomography
      In this paper, we use swept source optical coherence tomography combined with air-puff module (air-puff SS-OCT) to investigate the properties of the cornea. During OCT measurement the cornea was stimulated by short, air pulse, and corneal response was recorded. In this preliminary study, the air-puff SS-OCT instrument was applied to measure behavior of the porcine corneas under varied, well-controlled intraocular pressure conditions. Additionally, the biomechanical response of the corneal tissue ...
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    10. Coherence properties of fast frequency swept lasers revealed via full electric field reconstruction

      Coherence properties of fast frequency swept lasers revealed via full electric field reconstruction
      A novel, time-resolved interferometric technique is presented allowing the reconstruction of the complex electric field output of a fast frequency swept laser in a single-shot measurement. The power of the technique is demonstrated by examining a short cavity swept source designed for optical coherence tomography applications, with a spectral bandwidth of 18 THz. This novel analysis of the complete electric field reveals the modal structure and modal evolution of the ...
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    11. Optical Coherence Tomography of the Labial Salivary Glands Reveals Age-Related Differences in Women

      Optical Coherence Tomography of the Labial Salivary Glands Reveals Age-Related Differences in Women
      The labial minor salivary glands (LSGs) play a role in medical research and practice due to their superficial location and involvement in both systemic and localized diseases. Swept-source optical coherence tomography (OCT) is a noninvasive modality that enables in vivo , micrometer resolution, wide-field three-dimensional imaging in seconds. A purpose-built swept-source OCT instrument was employed to acquire three-dimensional datasets covering the area of 2.43 cm 2 of the mucosa of ...
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    12. Feature Of The Week 02/15/15: Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      Feature Of The Week 02/15/15: Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis
      Cystic fibrosis (CF) is a genetic disease that affects multiple organs due to the production of abnormally viscous mucus. Recurring pulmonary infections result in build-up of lung damage which leads to death. Intestinal, pancreatic, and hepatobiliary complications also occur, further aggravating the course of the disease. The molecular basis of CF is the dysfunction of the CF transmembrane conductance regulator (CFTR). CFTR-related disruption of transmembrane ion transport affects the exocrine ...
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    13. Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis
      The labial minor salivary glands (LSGs) are easily accessible mucus-secreting structures of the alimentary tract that may provide new information on the basis of gastrointestinal complications of cystic fibrosis (CF). It was shown that they are destructed in the course of cystic fibrosis. We employed wide-field, micrometer resolution in vivo optical coherence tomography to assess the surface density of LSGs in 18 patients with CF and 18 healthy subjects. The ...
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    14. Feature Of The Week 11/9/14: Dynamics of a Short Cavity Swept Source OCT Laser

      Feature Of The Week 11/9/14: Dynamics of a Short Cavity Swept Source OCT Laser
      Great advances in OCT speed and sensitivity have been possible due to the introduction of fast frequency swept laser sources. One of the most commonly used swept source devices is a short (~5 cm) cavity Fabry-Perot laser. We present both experimental characterisation and numerical modelling of such an OCT swept source and also analyse the underlying physics to better understand how such sources may be optimised. For the experimental characterisation ...
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    15. 1-15 of 25 1 2 »
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  2. About Karol Karnowski

    Karol Karnowski

    Karol Karnowski (b. 1979) received his MSc in physics from Nicholas Copernicus University (NCU), Torun, Poland. Presently he is a PhD student in Medical Physics Group managed by Dr Maciej Wojtkowski. His research interest includes ultra-high speed Swept Source OCT systems.