1. Karol Karnowski

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    1. Mentioned In 20 Articles

    2. Feature Of The Week 10/08/2017: Optical Coherence Microscopy as a Novel, Non-Invasive Method for the 4D Live Imaging of Early Mammalian Embryos

      Feature Of The Week 10/08/2017: Optical Coherence Microscopy as a Novel, Non-Invasive Method for the 4D Live Imaging of Early Mammalian Embryos
      ...apter in imaging-based preimplantation embryo diagnostics. For more information see recent Article . Courtesy Karol Karnowski from Nicolaus Copernicus University . Imaging of living cells based on traditional fluorescenc...
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    3. Optical coherence microscopy as a novel, non-invasive method for the 4D live imaging of early mammalian embryos

      Optical coherence microscopy as a novel, non-invasive method for the 4D live imaging of early mammalian embryos
      Imaging of living cells based on traditional fluorescence and confocal laser scanning microscopy has delivered an enormous amount of information critical for understanding biological processes in single cells. However, the requirement for a high numerical aperture and fluorescent markers still limits researchers ability to visualize the cellular architecture without causing short- and long-term photodamage. Optical coherence microscopy (OCM) is a promising alternative that circumvents the technical limitations of fluorescence imaging ...
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    4. Non-contact investigation of the corneal biomechanics with air-puff swept source optical coherence tomography

      Non-contact investigation of the corneal biomechanics with air-puff swept source optical coherence tomography
      In this paper, we use swept source optical coherence tomography combined with air-puff module (air-puff SS-OCT) to investigate the properties of the cornea. During OCT measurement the cornea was stimulated by short, air pulse, and corneal response was recorded. In this preliminary study, the air-puff SS-OCT instrument was applied to measure behavior of the porcine corneas under varied, well-controlled intraocular pressure conditions. Additionally, the biomechanical response of the corneal tissue ...
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    5. Coherence properties of fast frequency swept lasers revealed via full electric field reconstruction

      Coherence properties of fast frequency swept lasers revealed via full electric field reconstruction
      A novel, time-resolved interferometric technique is presented allowing the reconstruction of the complex electric field output of a fast frequency swept laser in a single-shot measurement. The power of the technique is demonstrated by examining a short cavity swept source designed for optical coherence tomography applications, with a spectral bandwidth of 18 THz. This novel analysis of the complete electric field reveals the modal structure and modal evolution of the ...
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    6. Optical Coherence Tomography of the Labial Salivary Glands Reveals Age-Related Differences in Women

      Optical Coherence Tomography of the Labial Salivary Glands Reveals Age-Related Differences in Women
      The labial minor salivary glands (LSGs) play a role in medical research and practice due to their superficial location and involvement in both systemic and localized diseases. Swept-source optical coherence tomography (OCT) is a noninvasive modality that enables in vivo , micrometer resolution, wide-field three-dimensional imaging in seconds. A purpose-built swept-source OCT instrument was employed to acquire three-dimensional datasets covering the area of 2.43 cm 2 of the mucosa of ...
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    7. Feature Of The Week 02/15/15: Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      Feature Of The Week 02/15/15: Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis
      Cystic fibrosis (CF) is a genetic disease that affects multiple organs due to the production of abnormally viscous mucus. Recurring pulmonary infections result in build-up of lung damage which leads to death. Intestinal, pancreatic, and hepatobiliary complications also occur, further aggravating the course of the disease. The molecular basis of CF is the dysfunction of the CF transmembrane conductance regulator (CFTR). CFTR-related disruption of transmembrane ion transport affects the exocrine ...
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    8. Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis
      The labial minor salivary glands (LSGs) are easily accessible mucus-secreting structures of the alimentary tract that may provide new information on the basis of gastrointestinal complications of cystic fibrosis (CF). It was shown that they are destructed in the course of cystic fibrosis. We employed wide-field, micrometer resolution in vivo optical coherence tomography to assess the surface density of LSGs in 18 patients with CF and 18 healthy subjects. The ...
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    9. Feature Of The Week 11/9/14: Dynamics of a Short Cavity Swept Source OCT Laser

      Feature Of The Week 11/9/14: Dynamics of a Short Cavity Swept Source OCT Laser
      Great advances in OCT speed and sensitivity have been possible due to the introduction of fast frequency swept laser sources. One of the most commonly used swept source devices is a short (~5 cm) cavity Fabry-Perot laser. We present both experimental characterisation and numerical modelling of such an OCT swept source and also analyse the underlying physics to better understand how such sources may be optimised. For the experimental characterisation ...
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    10. Dynamics of a short cavity swept source OCT laser

      Dynamics of a short cavity swept source OCT laser
      We investigate the behaviour of a short cavity swept source laser with an intra cavity swept filter both experimentally and theoretically. We characterise the behaviour of the device with real-time intensity measurements using a fast digital oscilloscope, showing several distinct regimes, most notably regions of mode-hopping, frequency sliding mode-locking and chaos. A delay differential equation model is proposed that shows close agreement with the experimental results. The model is also ...
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    11. Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT

      Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT
      Three-dimensional imaging of the mucosa of the lower lip and labial minor salivary glands is demonstrated in vivo using swept source optical coherence tomography (OCT) system at 1310 nm with modified interface. Volumetric data sets of the inner surface of the lower lip covering ~230 mm 2 field are obtained from patients with Sjgrens syndrome and a control group. OCT enables high-resolution visualization of mucosal architecture using cross-sectional images as ...
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    12. Improved measurement of vibration amplitude in dynamic optical coherence elastography

      Improved measurement of vibration amplitude in dynamic optical coherence elastography
      Optical coherence elastography employs optical coherence tomography (OCT) to measure the displacement of tissues under load and, thus, maps the resulting strain into an image, known as an elastogram. We present a new improved method to measure vibration amplitude in dynamic optical coherence elastography. The tissue vibration amplitude caused by sinusoidal loading is measured from the spread of the Doppler spectrum, which is extracted using joint spectral and time domain ...
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    13. Fourier domain OCT imaging of American cockroach nervous system

      Fourier domain OCT imaging of American cockroach nervous system
      In this pilot study we demonstrate results of structural Fourier domain OCT imaging of the nervous system of Periplaneta americana L. (American cockroach). The purpose of this research is to develop an OCT apparatus enabling structural imaging of insect neural system. Secondary purpose of the presented research is to develop methods of the sample preparation and handling during the OCT imaging experiments. We have performed imaging in the abdominal nerve ...
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    14. 1-15 of 20 1 2 »
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  2. About Karol Karnowski

    Karol Karnowski

    Karol Karnowski (b. 1979) received his MSc in physics from Nicholas Copernicus University (NCU), Torun, Poland. Presently he is a PhD student in Medical Physics Group managed by Dr Maciej Wojtkowski. His research interest includes ultra-high speed Swept Source OCT systems.