1. Kang Zhang

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    1. Mentioned In 27 Articles

    2. Extravascular Optical Coherence Tomography - Evaluation of Carotid Atherosclerosis and Pravastatin Therapy

      Extravascular Optical Coherence Tomography - Evaluation of Carotid Atherosclerosis and Pravastatin Therapy

      Background and Purpose— Extravascular optical coherence tomography (OCT), as a noninvasive imaging methodology with micrometer resolution, was evaluated in a murine model of carotid atherosclerosis by way of assessing the efficacy of pravastatin therapy. Methods— An OCT device was engineered for extravascular plaque imaging. Wild-type mice and apolipoprotein E–deficient (ApoE −/− ) mice were randomized to 3 treatment groups: (1) wild-type on a diet of standard rodent chow (n=13); (2) ApoE −/− on a high-fat, atherosclerotic diet (HFD; n=13); and (3) ApoE −/− on a HFD given daily pravastatin (n=13). Mice were anesthetized and the left common carotid was surgically ...

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    3. Graphics Processing Unit-Based Ultrahigh Speed Real-Time Fourier Domain Optical Coherence Tomography

      Graphics Processing Unit-Based Ultrahigh Speed Real-Time Fourier Domain Optical Coherence Tomography

      This paper describes a series of novel graphics processing unit (GPU)-based image reconstruction and visualization methods that we developed for realizing ultrahigh speed, real-time Fourier domain optical coherence tomography (FD-OCT). Several GPU-based algorithms including high-speed linear/cubic interpolation, gridding-based nonuniform fast Fourier transform (NUFFT), numerical dispersion compensation, and multi-GPU implementation were developed to improve the point-spread function, SNR roll-off, and stability of the system. Full-range complex-conjugate-free FD-OCT was also implemented on the GPU architecture to double the imaging range and to improve the SNR. The maximum processing speed of >3 Gigavoxels/s (>6 Mega-A-scans/s of 1024-pixel ...

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    4. Real-Time, Three-Dimensional Optical Coherence Tomography System

      Real-Time, Three-Dimensional Optical Coherence Tomography System

      A real-time, three-dimensional optical coherence tomography system includes an optical interferometer configured to illuminate a target with light and to receive light returned from the target; an optical detection system arranged in an optical path of light from the optical interferometer after being returned from the target, the optical detection system providing output data signals; and a data processing system adapted to communicate with the optical detection system to receive the output data signals. The data processing system includes a parallel processor configured to process the output data signals to provide real-time, three-dimensional optical coherence tomography images of the target.

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    5. Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries

      Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries

      The authors describe the development of an ultrafast three-dimensional (3D) optical coherence tomography (OCT) imaging system that provides real-time intraoperative video images of the surgical site to assist surgeons during microsurgical procedures. This system is based on a full-range complex conjugate free Fourier-domain OCT (FD-OCT). The system was built in a CPU-GPU heterogeneous computing architecture capable of video OCT image processing. The system displays at a maximum speed of 10  volume/?startsend? for an image volume size of 160×80×1024 (X×Y×Z) pixels. We have used this system to visualize and guide two prototypical microsurgical maneuvers: microvascular anastomosis ...

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    6. Graphics processing unit based ultrahigh speed real-time multidimensional Fourier domain optical coherence tomography

      Graphics processing unit based ultrahigh speed real-time multidimensional Fourier domain optical coherence tomography

      In this paper, we systematically presented a series of graphics processing unit (GPU) based data processing methods for ultrahigh speed, real-time Fourier Domain optical coherence tomography (FD-OCT): GPU based algorithms including high-speed linear/cubic interpolation, non-uniform fast Fourier transform (NUFFT), numerical dispersion compensation, and multi-GPU implementation were developed to improve the image quality and stability of the system. Full-range complex-conjugate-free FD-OCT was also implemented on the GPU architecture to double the imaging range and to improve SNR. The maximum processing speed of >3.0 Giga-Voxel/second (>6.0 Mega-A-scan/ second of 1024-pixel FD-OCT) was achieved using NVIDIA's latest GPU ...

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    7. In-vivo gingival sulcus imaging using full-range, complex-conjugate-free, endoscopic spectral domain optical coherence tomography

      In-vivo gingival sulcus imaging using full-range, complex-conjugate-free, endoscopic spectral domain optical coherence tomography

      Frequent monitoring of gingival sulcus will provide valuable information for judging the presence and severity of periodontal disease. Optical coherence tomography, as a 3D high resolution high speed imaging modality is able to provide information for pocket depth, gum contour, gum texture, gum recession simultaneously. A handheld forward-viewing miniature resonant fiber-scanning probe was developed for in-vivo gingival sulcus imaging. The fiber cantilever driven by magnetic force vibrates at resonant frequency. A synchronized linear phase-modulation was applied in the reference arm by the galvanometer-driven reference mirror. Full-range, complex-conjugate-free, real-time endoscopic SD-OCT was achieved by accelerating the data process using graphics processing ...

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    8. Real-time numerical dispersion compensation using graphics processing unit for Fourier-domain optical coherence tomography

      Real-time numerical dispersion compensation using graphics processing unit for Fourier-domain optical coherence tomography
      Numerical dispersion compensation for both standard and full-range Fourier-domain optical coherence tomography (FD-OCT) on the graphics processing unit (GPU) architecture has been implemented. The data acquisition, processing and image display were performed on a multi-thread, CPU-GPU heterogeneous computing system. The real-time ultra-high-resolution full-range complex-conjugate-free FD-OCT imaging was demonstrated at 68.4 frame/s with a frame size of 1024 (lateral) by 2048 (axial) pixels.
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    9. 1-15 of 27 1 2 »
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  2. About Kang Zhang

    Kang Zhang

    Kang Zhang is currently a researcher in the GE Global Research Center, New York. He obtained the Ph. D. and M. S. E. degrees in Electrical and Computer Engineering from The Johns Hopkins University, in 2011 and 2009 respectively, and the B. S. degree in physics from Nankai University, China, in 2007.  His research interests include optical sensing & imaging, high data-throughput imaging platform, interventional imaging, smart surgical devices, and GPGPU applications. From 2009 to 2010, Kang worked as an ORISE Research Fellow for the U. S. Food and drug Administration (FDA), where he developed optical metrology methods for medical device evaluation.  He received the Chinese Government Award for Outstanding Self-Financed Students Abroad in 2010.