1. K. U. Leuven

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    1. Mentioned In 64 Articles

    2. Automatic Segmentation of the Optic Nerve Head Region in Optical Coherence Tomography

      Explore ScienceDirect Ophthalmology
      Automatic Segmentation of the Optic Nerve Head Region in Optical Coherence Tomography
      The optic nerve head (ONH) represents the intraocular section of the optic nerve, which is prone to damage by intraocular pressure (IOP). The advent of optical coherence tomography (OCT) has enabled the evaluation of novel ONH parameters, namely the depth and curvature of the lamina cribrosa (LC). Together with the Bruch's membrane minimum-rim-width (BMO-MRW), these seem to be promising ONH parameters for diagnosis and monitoring of retinal diseases such ...
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      Mentions: K. U. Leuven University of Coimbra Erasmus University

    3. Optical Coherence Tomography of Coronary Plaque Progression and Destabilization: JACC Focus Seminar Part 3/3

      Explore ScienceDirect Cardiology
      Optical Coherence Tomography of Coronary Plaque Progression and Destabilization: JACC Focus Seminar Part 3/3
      The development of optical coherence tomography (OCT) has revolutionized our understanding of coronary artery disease. In vivo OCT research has paralleled with advances in computational fluid dynamics, providing additional insights in the various hemodynamic factors influencing plaque growth and stability. Recent OCT studies introduced a new concept of plaque healing in relation to clinical presentation. In addition to known mechanisms of acute coronary syndromes such as plaque rupture and plaque ...
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      Mentions: Mount Sinai School of Medicine Massachusetts General Hospital Harvard University

    4. Hyperspectral Imaging, OCT Team to Detect Early Biomarkers of Alzheimer's Disease

      Explore Photonics.com Neurology , Ophthalmology
      Hyperspectral Imaging, OCT Team to Detect Early Biomarkers of Alzheimer's Disease
      A team of scientists and engineers from Katholieke Universiteit (KU) Leuven, Universitair Ziekenhuis (UZ) Leuven, and the research organization VITO, collaborating with the international research and development group imec, used imecs hyperspectral snapshot camera, SNAPSCAN, to collect information from 16 spectral bands (460 to 620nm, 10-nm bandwidth) in a single capture. The potential for retinal imaging to serve as a tool for the early diagnosis of Alzheimers disease is the ...
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      Mentions: K. U. Leuven

    5. OCTA Multilayer and Multisector Peripapillary Microvascular Modeling for Diagnosing and Staging of Glaucoma

      Explore TVST Journal Ophthalmology
      OCTA Multilayer and Multisector Peripapillary Microvascular Modeling for Diagnosing and Staging of Glaucoma
      Purpose: To develop and assess an automatic procedure for classifying and staging glaucomatous vascular damage based on optical coherence tomography angiography (OCTA) imaging. Methods: OCTA scans (Zeiss Cirrus 5000 HD-OCT) from a random eye of 39 healthy subjects and 82 glaucoma patients were used to develop a new classification algorithm based on multilayer and multisector information. The averaged circumpapillary retinal nerve fiber layer (RNFL) thickness was also collected. Three models ...
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      Mentions: Delft University of Technology K. U. Leuven

    6. Combination of snapshot hyperspectral retinal imaging and optical coherence tomography to identify Alzheimer’s disease patients

      Explore Alzheimer's Research & Therapy Ophthalmology
      Combination of snapshot hyperspectral retinal imaging and optical coherence tomography to identify Alzheimer’s disease patients
      The eye offers potential for the diagnosis of Alzheimers disease (AD) with retinal imaging techniques being explored to quantify amyloid accumulation and aspects of neurodegeneration. To assess these changes, this proof-of-concept study combined hyperspectral imaging and optical coherence tomography to build a classification model to differentiate between AD patients and controls.
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      Mentions: K. U. Leuven

    7. Circadian variations in pathogenesis of ST-segment elevation myocardial infarction: an optical coherence tomography study

      Explore Home - Springer Cardiology
      Circadian variations in pathogenesis of ST-segment elevation myocardial infarction: an optical coherence tomography study
      Previous studies have reported a circadian variation in the onset of ST-segment elevation myocardial infarction (STEMI). However, underlying mechanisms for the circadian variation have not been fully elucidated. We investigated the relationship between onset of STEMI and the underlying pathology using optical coherence tomography (OCT). Patients with a diagnosis of STEMI were selected from a multicenter OCT registry. Patients were divided into 4 groups based on the estimated time of ...
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      Mentions: Massachusetts General Hospital Harvard University Nippon Medical School

    8. KU Leuven leads €6 million research project on heart disease and dementia

      Explore KU Leuven nieuws Cardiology , Neurology
      KU Leuven leads €6 million research project on heart disease and dementia
      The starting point is an observation that people with conditions such as high blood pressure and obesity, or who are simply getting old, have a higher risk of certain kinds of dementia and heart disease. In particular, they seem to have a greater chance of developing vascular dementia, which is associated with reduced blood flow to the brain, and diastolic heart failure, which happens when the heart muscle cannot relax ...
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      Mentions: University College London Academic Hospital Maastricht K. U. Leuven

    9. PHD POSITION – OPTICAL COHERENCE TOMOGRAPHY ON AGRO-FOOD PRODUCTS

      Explore Optical Coherence Tomography News Other Non-Medical , Jobs & Studentships
      PHD POSITION – OPTICAL COHERENCE TOMOGRAPHY ON AGRO-FOOD PRODUCTS
      (ref. BAP-2019-576) The MeBioS group performs groundbreaking research on innovative sensor technologies and the associated data analysis methods to understand and control the quality of products and ongoing processes. The research on sensors mainly focusses on optical sensor systems (spectroscopy, hyperspectral imaging, thermography, smart cameras,). While the data research involves the optimal design of experiments, chemometrics, process monitoring and control, as well as artificial intelligence and deep learning. OCT/OCM ...
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      Mentions: K. U. Leuven

    10. Optical coherence tomography—A review of the opportunities and challenges for postharvest quality evaluation

      Explore ScienceDirect NDE/NDT , Other Non-Medical
      Optical coherence tomography—A review of the opportunities and challenges for postharvest quality evaluation
      Optical Coherence Tomography (OCT) is an established non-destructive and contactless photonic technique which has now been shown to be suitable for monitoring the near-surface internal structure of tissues in stored fruit and vegetables. Such real-time cross-sectional imaging allows for better visualisation and understanding of the temporal changes in internal structure. However, despite these advantages, problems persist around the trade-off between imaging resolution and penetration depth, image analysis and data processing ...
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      Mentions: K. U. Leuven

    11. Neoatherosclerosis in Patients With Coronary Stent Thrombosis: Findings From Optical Coherence Tomography Imaging (A Report of the PRESTIGE Consortium)

      Explore ScienceDirect Cardiology
      Neoatherosclerosis in Patients With Coronary Stent Thrombosis: Findings From Optical Coherence Tomography Imaging (A Report of the PRESTIGE Consortium)
      Objectives The purpose of this study was to assess neoatherosclerosis in a registry of prospectively enrolled patients presenting with stent thrombosis using optical coherence tomography . Background In-stent neoatherosclerosis was recently identified as a novel disease manifestation of atherosclerosis after coronary stent implantation. Methods Angiography and intravascular optical coherence tomography were used to investigate etiologic factors of neoatherosclerosis in patients presenting with stent thrombosis 1 year after implantation (very late stent ...
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      Mentions: Azienda Ospedaliera San Paolo K. U. Leuven Ludwig Maximilian University of Munich

    12. Optical Coherence Tomography Angiography in Glaucoma: A Review

      Explore Karger Publishers Ophthalmology
      Optical Coherence Tomography Angiography in Glaucoma: A Review
      Background: Glaucoma is the leading cause of irreversible blindness worldwide. Several techniques exist for the diagnosis and follow-up of patients. Optical coherence tomography (OCT) angiography (OCTA) is a recently developed technique that provides a quantitative assessment of the microcirculation of the retina and choroid in a fast, noninvasive way. Despite it being a novel technique, several publications have already been done in the glaucoma field. However, a summary of findings ...
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      Mentions: K. U. Leuven

    13. 5-Year clinical follow-up of the COBRA (complex coronary bifurcation lesions: Randomized comparison of a strategy using a dedicated self-expanding biolimus A9-eluting stent vs. a culotte strategy using everolimus-eluting stents) study

      Explore Wiley Online Library Cardiology
      5-Year clinical follow-up of the COBRA (complex coronary bifurcation lesions: Randomized comparison of a strategy using a dedicated self-expanding biolimus A9-eluting stent vs. a culotte strategy using everolimus-eluting stents) study
      Objectives We evaluated healing responses with optical coherence tomography, and long-term clinical outcomes after treatment with a dedicated stent versus a conventional culotte technique. Background Dedicated bifurcation stents have been proposed as an alternative treatment for coronary bifurcation lesions. The long-term performance of dedicated stents versus conventional dual-stent techniques for the treatment of complex coronary bifurcation lesions is unknown. Methods Forty patients with true coronary bifurcation lesions were randomized to ...
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      Mentions: K. U. Leuven

    14. In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study

      Explore Home - Springer Cardiology
      In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study
      We sought to assess in-stent variations in fractional flow reserve (FFR) in patients with previous percutaneous coronary intervention (PCI) and to associate any drop in FFR with findings by optical coherence tomography (OCT) imaging. Suboptimal post-PCI FFR values were previously associated with poor outcomes. It is not known to which extent in-stent pressure loss contributes to reduced FFR. In this single-arm observational study, 26 patients who previously underwent PCI with ...
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      Mentions: Leiden University K. U. Leuven Shanghai Jiao Tong University

    15. EuOptical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chro

      Explore eurointervention.org Cardiology
      EuOptical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chro
      Aims: The PRISON IV trial investigated the next-generation sirolimus-eluting stent (SES) with ultra-thin struts and biodegradable polymer against the second-generation everolimus-eluting stent (EES) with thin struts and durable polymer in patients with successfully recanalised chronic total occlusions (CTO). In this study, we examined the secondary optical coherence tomography endpoints. Methods and results: The main PRISON IV trial randomised 330 patients to either SES or EES. At nine months, 281 (85 ...
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      Mentions: Academic Medical Center at the University of Amsterdam K. U. Leuven

    16. Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium

      Explore Circulation Cardiology
      Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium
      Background Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed a prospective, multicenter study to evaluate OCT findings in patients with ST. Methods Consecutive patients presenting with ST were prospectively enrolled in a registry using a centralized telephone registration system. After angiographic confirmation of ST, OCT imaging of the culprit vessel was performed ...
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      Mentions: Azienda Ospedaliera San Paolo K. U. Leuven Ludwig Maximilian University of Munich
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  4. About K. U. Leuven

    K. U. Leuven

    Catholic University of Leuven (Katholieke Universiteit Leuven ) is situated in the heart of Western Europe and has been a centre of learning for almost six centuries. Founded in 1425 by Pope Martin V, K. U.Leuven bears the double honour of being the oldest existent Catholic university in the world and the oldest university in the Low Countries.

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