1. Justis P. Ehlers

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    1. Mentioned In 70 Articles

    2. Optical coherence tomography angiography characteristics of choroidal neovascularization requiring varied dosing frequencies in treat-and-extend management: An analysis of the AVATAR study

      Optical coherence tomography angiography characteristics of choroidal neovascularization requiring varied dosing frequencies in treat-and-extend management: An analysis of the AVATAR study
      ...ction, analysis and interpretation of the data, and in the preparation, review or approval of the manuscript. Justis P. Ehlers, M.D. has had full access to all the data in the study and takes responsibility for the integ...
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    3. IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION

      IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION
      Purpose: To compare optical coherence tomography angiography ( OCTA ) review strategies for optimizing choroidal neovascularization ( CNV ) detection . Methods: Eyes with CNV in the differential diagnosis were imaged with the Avanti RTVue XR HD (Optovue, Fremont, CA). Three modalities of review for CNV presence were used in each case: a single report generated using automated segmentation within Avanti software; a continuous slab descent video OCTA export; and a manual segmentation approach using ...
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    4. Predictive Model for Macular Hole Closure Speed: Insights From Intraoperative Optical Coherence Tomography

      Predictive Model for Macular Hole Closure Speed: Insights From Intraoperative Optical Coherence Tomography
      Purpose : To establish a predictive model of macular hole (MH) closure speed. Methods : This study was a post hoc analysis of eyes that underwent full-thickness MH repair in the prospective PIONEER intraoperative optical coherence tomography (iOCT) study. The Bioptigen SDOIS system was used for iOCT imaging. All patients underwent standard small-gauge vitrectomy with internal limiting membrane (ILM) peeling, gas tamponade, and postoperative facedown positioning. Before vitrectomy and after ILM peeling ...
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    5. Intraoperative OCT Features and Postoperative Ellipsoid Mapping in Primary Macula-Involving Retinal Detachments from the PIONEER Study

      Intraoperative OCT Features and Postoperative Ellipsoid Mapping in Primary Macula-Involving Retinal Detachments from the PIONEER Study
      Purpose Intraoperative OCT (iOCT) has enabled visualization of subtle structural details during surgical interventions, including retinal detachment repair. The purpose of this study is to evaluate iOCT findings during retinal detachment repair and assess their impact on anatomic and functional outcomes, including outer retinal integrity. Design The PIONEER iOCT study is a prospective cohort IRB-approved study. Subjects Subjects in the PIONEER study undergoing surgical repair for primary macula-involving retinal detachment ...
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    6. Clinic evaluation via outer retinal layer assessment

      Clinic evaluation via outer retinal layer assessment
      Systems and methods are provided for evaluating an eye of a patient from a set of OCT data. A layer segmentation component is configured to identify and segment a plurality of retinal layers within the set of OCT data. The plurality of layers include a layer of interest. A mapping component is configured to generate at least one of an en face representation of the layer of interest and a ...
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    7. Outer Retinal Assessment Using Spectral-Domain Optical Coherence Tomography in Patients With Alzheimer's and Parkinson's Disease

      Outer Retinal Assessment Using Spectral-Domain Optical Coherence Tomography in Patients With Alzheimer's and Parkinson's Disease
      Purpose : To investigate outer retinal parameters among patients with various chronic neurodegenerative disorders by using spectral-domain coherence tomography (OCT) in a prospective cross-sectional cohort study. Methods : A total of 132 participants were enrolled following a comprehensive diagnostic evaluation with neurologic, neuropsychology, and magnetic resonance imaging volumetric evaluations. Participants were 50 years or older, either diagnosed with Alzheimer's disease (AD) dementia, amnestic mild cognitive impairment (MCI), non-AD dementia, Parkinson's ...
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    8. Choriocapillaris and retinal vascular plexus density of diabetic eyes using split-spectrum amplitude decorrelation spectral-domain optical coherence tomography angiography

      Choriocapillaris and retinal vascular plexus density of diabetic eyes using split-spectrum amplitude decorrelation spectral-domain optical coherence tomography angiography
      Background/aims Split-spectrum amplitude decorrelation angiography for spectral-domain optical coherence tomography has enabled detailed, non-invasive assessment of vascular flow. This study evaluates choriocapillaris and retinal capillary perfusion density (CPD) in diabetic eyes using optical coherence tomography angiography (OCTA). Methods Records of 136 eyes that underwent OCTA imaging at a single institution were reviewed. Eyes were grouped as non-diabetic controls (37 eyes), patients with diabetes mellitus (DM) without diabetic retinopathy (DM ...
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    9. The DISCOVER Study 3-Year Results

      The DISCOVER Study 3-Year Results
      Purpose To report the 3-year assessment of feasibility and usefulness of microscope-integrated intraoperative OCT (iOCT) during ophthalmic surgery. Design Prospective, consecutive case series. Participants Adult participants undergoing incisional ophthalmic surgery with iOCT imaging who consented to be enrolled in the Determination of Feasibility of Intraoperative Spectral-Domain Microscope Combined/Integrated OCT Visualization during En Face Retinal and Ophthalmic Surgery (DISCOVER) study. Methods The DISCOVER study is a single-site, multisurgeon, institutional review ...
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    10. Comparison of OCT Angiography Review Strategies to Identify Vascular Abnormalities in the AVATAR Study

      Comparison of OCT Angiography Review Strategies to Identify Vascular Abnormalities in the AVATAR Study
      Purpose To compare review strategies for OCT angiography (OCTA) for multiple disease features found in common diseases of the choroid and retina. Design Prospective, observational study. Participants Patients with macular disease undergoing routine spectral-domain OCT. Methods Eyes were imaged with the Avanti RTVue XR HD (Optovue, Fremont, CA), and the split-spectrum amplitude decorrelation angiography algorithm software was used for OCTA performance. Scans were reviewed by 2 masked expert reviewers. A ...
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    11. Intraoperative Optical Coherence Tomography–Assisted Chorioretinal Biopsy in the DISCOVER Study

      Intraoperative Optical Coherence Tomography–Assisted Chorioretinal Biopsy in the DISCOVER Study
      Infiltrative conditions such as lymphoproliferative disorders, amyloidosis, and autoimmune and infectious disorders can overlap in their ophthalmic clinical presentation. Malignancies and other infiltrative disease processes can masquerade as ocular inflammatory conditions. To obtain a definitive clinical diagnosis, a biopsy of the choroid and/or retina may be warranted. When conducting biopsy of intraocular structures, preoperative understanding of retinal microanatomy frequently informs surgical planning. Although office-based, clinical table-top optical coherence tomography ...
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    12. Cleveland Clinic Receives a NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic Receives a NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery
      ...s. This research activity will focus on translating OCT technology into the operating room and will be led by Justis P. Ehlers, MD, of the Cleveland Clinic Cole Eye Institute. Dr. Ehlers is a highly trained retina surgeo...
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    13. Intraoperative optical coherence tomography-compatible surgical instruments for real-time image-guided ophthalmic surgery

      Intraoperative optical coherence tomography-compatible surgical instruments for real-time image-guided ophthalmic surgery
      Intraoperative optical coherence tomography (OCT) is a potentially transformational technology that is now commercially available to ophthalmic surgeons. Currently, the use of the technology is primarily limited to a stop and image approach due to the lack of OCT compatibility with surgical instrumentation. In this report, we describe multiple OCT-compatible surgical instruments that were developed for various surgical needs, based on previous evaluation of potential surgical materials for optical features ...
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  2. About Justis P. Ehlers

    Justis P. Ehlers

    Justis P. Ehlers is a staff physician at the Cole Eye Institute, Vitreoretinal Service at Cleveland Clinic.