1. Juan Luis Gutiérrez-Chico

    0 Comments Leave a Comment

    1-15 of 20 1 2 »
    1. Mentioned In 20 Articles

    2. Endothelial progenitor cells and plaque burden in stented coronary artery segments: an optical coherence tomography study six months after elective PCI

      Endothelial progenitor cells and plaque burden in stented coronary artery segments: an optical coherence tomography study six months after elective PCI
      Background Endothelial progenitor cells (EPC) are involved in neovascularization and endothelial integrity. They might be protective in atherosclerosis. Optical coherence tomography (OCT) is a precise intracoronary imaging modality that allows assessment of subintimal plaque development. We evaluated the influence of EPC on coronary plaque burden in stable disease and implemented a novel computational plaque analysis algorithm using OCT. Methods Forty-three patients (69.8% males, 69.6 7.7 years) were ...
      Read Full Article
    3. Implantation of magnesium-bioresorbable scaffolds in a bifurcation under optical coherence tomography guidance

      Implantation of magnesium-bioresorbable scaffolds in a bifurcation under optical coherence tomography guidance
      A 68-years-old female with positive test of ischaemia in the anterior wall presented a severe coronary bifurcation lesion in the anterior descending (LAD) and first diagonal (D1) arteries, Medina 010 ( Panel A ; Supplementary material online, Video 1 ). OCT showed lipid-rich plaques in both vessels, extending proximally and distally to the take-off of the D1 (optical Medina 110). Balloons and scaffolds were sized
      Read Full Article
    4. Time course of vascular response after an a priori strategy of bare metal stent implantation post-dilated with a paclitaxel-coated balloon: Implementation of a three dimensional analysis algorithm with optical coherence tomography

      Time course of vascular response after an a priori strategy of bare metal stent implantation post-dilated with a paclitaxel-coated balloon: Implementation of a three dimensional analysis algorithm with optical coherence tomography
      Background: An a priori combined therapy of a bare metal stent (BMS) post-dilated with a paclitaxel-coated balloon (PCB) was investigated with optical coherence tomography (OCT) at 2- and 6 months regarding vessel response. Previous studies have shown inconsistent results and the time course of vessel healing after such an interventional strategy is unknown. Methods: Thirty-three de novo lesions in 32 patients were electively treated. Six-month OCT analysis was available in ...
      Read Full Article
    5. Impact of Side Branch Modeling on Computation of Endothelial Shear Stress in Coronary Artery Disease Coronary Tree Reconstruction by Fusion of 3D Angiography and OCT

      Impact of Side Branch Modeling on Computation of Endothelial Shear Stress in Coronary Artery Disease Coronary Tree Reconstruction by Fusion of 3D Angiography and OCT
      Background Computational fluid dynamics allow virtual evaluation of coronary physiology and shear stress (SS). Most studies hitherto assumed the vessel as a single conduit without accounting for the flow through side branches. Objectives This study sought to develop a new approach to reconstruct coronary geometry that also computes outgoing flow through side branches in hemodynamic and biomechanical calculations, using fusion of optical coherence tomography (OCT) and 3-dimensional (3D) angiography. Methods ...
      Read Full Article
    6. Incomplete Stent Apposition Causes High Shear Flow Disturbances and Delay in Neointimal Coverage as a Function of Strut to Wall Detachment Distance: Implications for the Management of Incomplete Stent Apposition

      Incomplete Stent Apposition Causes High Shear Flow Disturbances and Delay in Neointimal Coverage as a Function of Strut to Wall Detachment Distance: Implications for the Management of Incomplete Stent Apposition
      ...nt Distance Implications for the Management of Incomplete Stent Apposition 1. Nicolas Foin, MSc, PhD*, 2. Juan Luis Gutiérrez-Chico, MD, PhD*, 3. Shimpei Nakatani, MD*, 4. Ryo Torii, MSc, PhD*, 5. Christos V. Bourant...
      Read Full Article
    7. In vivo evaluation of neointimal healing after stenting with optical coherence tomography (Thesis)

      In vivo evaluation of neointimal healing after stenting with optical coherence tomography (Thesis)
      Ischemic heart disease is still today the first cause of mortality in the world, especially in the developed countries. The vast majority of cases are due to atherosclerosis, a complex systemic degenerative process resulting in cholesterol accumulation in the extra-cellular space of the arterial intima, with inflammation, foam-cells formation, and necrosis. The clinical manifestations of coronary atherosclerosis comprise from stable angina, due to flow-limiting stenosis of the artery, to acute ...
      Read Full Article
    8. Tissue coverage and neointimal hyperplasia in overlap versus nonoverlap segments of drug-eluting stents 9 to 13 months after implantation: In vivo assessment with optical coherence tomography

      Tissue coverage and neointimal hyperplasia in overlap versus nonoverlap segments of drug-eluting stents 9 to 13 months after implantation: In vivo assessment with optical coherence tomography
      Background: Histologic experimental studies have reported incomplete neointimal healing in overlapping with respect to nonoverlapping segments in drug-eluting stents (DESs), but these observations have not been confirmed in human coronary arteries hitherto. On the contrary, angiographic and optical coherence tomography studies suggest that DES overlap elicits rather an exaggerated than an incomplete neointimal reaction.Methods: Optical coherence tomography studies from 2 randomized trials including sirolimus-eluting, biolimus-eluting, everolimus-eluting, and zotarolimus-eluting stents ...
      Read Full Article
    9. Plaque sealing and passivation with a mechanical self-expanding low outward force nitinol VShield device for the treatment of intravascular ultrasound and optical coherence tomography-derived thin cap fibroatheromas (TCFAS) in native coronary arteries

      Plaque sealing and passivation with a mechanical self-expanding low outward force nitinol VShield device for the treatment of intravascular ultrasound and optical coherence tomography-derived thin cap fibroatheromas (TCFAS) in native coronary arteries
      Aims: The aim of the pilot SECRITT trial was to evaluate the safety and feasibility of sealing the high risk IVUS and optical coherence tomography-derived thin cap fibroatheroma (TCFA), with a dedicated nitinol self-expanding vShield device. Methods and results: After screening with angiography, fractional flow reserve (FFR), intravascular ultrasound virtual histology (IVUS-VH) and optical coherence tomography (OCT), 23 patients met enrolment criteria (presence of non-obstructive VH-derived TCFA lesion with thin ...
      Read Full Article
    10. Differences in Neointimal Thickness Between the Adluminal and the Abluminal Sides of Malapposed and Side-Branch Struts in a Polylactide Bioresorbable Scaffold: Evidence In Vivo About the Abluminal Healing Process

      Differences in Neointimal Thickness Between the Adluminal and the Abluminal Sides of Malapposed and Side-Branch Struts in a Polylactide Bioresorbable Scaffold: Evidence In Vivo About the Abluminal Healing Process
      ...rection of acute malapposition involves neointimal growth from the strut to the vessel wall or bidirectional. Juan Luis Gutiérrez-Chico, MD, PhD*, Frank Gijsen, MSc, PhD, Evelyn Regar, MD, PhD*, Jolanda Wentzel, MSc, PhD...
      Read Full Article
    11. Residual atherothrombotic material after stenting in acute myocardial infarction — An optical coherence tomographic evaluation

      Residual atherothrombotic material after stenting in acute myocardial infarction — An optical coherence tomographic evaluation
      Background Thrombus aspiration (TA) in patients with ST segment elevation myocardial infarction (STEMI) results in a better myocardial perfusion. Optical coherence tomography (OCT) after stenting in STEMI, however, often reveals residual atherothrombotic material. We assessed the feasibility of quantification of residual atherothrombotic burden and its relation to indices of myocardial perfusion. The effect of TA on residual in-stent atherothrombotic burden (ATB) is explored. Methods and results Forty patients with STEMI ...
      Read Full Article
    12. Response to Letter Regarding Article, “Delayed Coverage in Malapposed and Side-Branch Struts With Respect to Well-Apposed Struts in Drug-Eluting Stents: In Vivo Assessment With Optical Coherence Tomography”

      Response to Letter Regarding Article, “Delayed Coverage in Malapposed and Side-Branch Struts With Respect to Well-Apposed Struts in Drug-Eluting Stents: In Vivo Assessment With Optical Coherence Tomography”
      ...spect to Well-Apposed Struts in Drug-Eluting Stents: In Vivo Assessment With Optical Coherence Tomography” 1. Juan Luis Gutiérrez-Chico, MD, PhD, FESC; 2. Evelyn Regar, MD, PhD, FESC; 3. Takayuki Okamura, MD, PhD; 4. Joa...
      Read Full Article
    13. Vascular Tissue Reaction to Acute Malapposition in Human Coronary Arteries: Sequential Assessment With Optical Coherence Tomography

      Vascular Tissue Reaction to Acute Malapposition in Human Coronary Arteries: Sequential Assessment With Optical Coherence Tomography
      Background—The vascular tissue reaction to acute incomplete stent apposition (ISA) is not well known. The aim of this study was to characterize the vascular response to acute ISA in vivo and to look for predictors of incomplete healing. Methods and Results—Optical coherence tomography studies of 66 stents of different designs, implanted in 43 patients enrolled in 3 randomized trials, were analyzed sequentially after implantation and at 6 to ...
      Read Full Article
    14. Spatial Distribution and Temporal Evolution of Scattering Centers by Optical Coherence Tomography in the Poly(L-Lactide) Backbone of a Bioresorbable Vascular Scaffold

      Spatial Distribution and Temporal Evolution of Scattering Centers by Optical Coherence Tomography in the Poly(L-Lactide) Backbone of a Bioresorbable Vascular Scaffold
      ...e polymer during crimp-deployment, ruling out any major role of hydrolysis or other time-dependent processes. Juan Luis Gutiérrez-Chico1), Maria D. Radu1), Roberto Diletti1), Alexander Sheehy2), Mary Beth Kossuth2), Jame...
      Read Full Article
    15. 1-15 of 20 1 2 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Juan Luis Gutiérrez-Chico

    Juan Luis Gutiérrez-Chico

    Juan Luis Gutiérrez-Chico is an interventional cardiologist with the Erasmus Medical Center, Thoraxcentrum, Interventional Cardiology Department in Rotterdam, The Netherlands.