1. Joseph A. Izatt

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    1. Mentioned In 292 Articles

    2. Photoreceptor Layer Thinning over Drusen in Eyes with Age-Related Macular Degeneration Imaged In Vivo with Spectral-Domain Optical Coherence Tomography

      PURPOSE: Detect changes in the neurosensory retina using spectral-domain optical coherence tomography (SD OCT) imaging over drusen in age-related macular degeneration (AMD). Quantitative imaging biomarkers may aid in defining risk of disease progression. DESIGN: Cross-sectional, case-control study evaluating SD OCT testing in AMD. PARTICIPANTS AND CONTROLS: Seventeen eyes of 12 subjects with nonneovascular AMD and drusen and 17 eyes of 10 age-matched control subjects. METHODS: Spectral-domain OCT imaging across the ...
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    3. Measurement of total blood flow in the normal human retina using Doppler Fourier-domain optical coherence tomography

      Aim: To measure total retinal blood flow in normal human eyes using Doppler Fourier-domain optical coherence tomography (FD-OCT). Methods: 10 normal people aged 35 to 69 years were measured for the right eye using Doppler FD-OCT. Double circular scans around the optic nerve heads were used. Four pairs of circular scans that transected all retinal branch vessels were completed in 2 seconds. Total retinal blood flow was obtained by summing ...
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    4. Functional Spectral Domain Optical Coherence Tomography Imaging (Thesis)

      Functional Spectral Domain Optical Coherence Tomography Imaging (Thesis)
      Spectral Domain Optical Coherence Tomography (SDOCT) is a high-speed, high resolution imaging modality capable of structural and functional resolution of tissue microstructure. SDOCT fills a niche between histology and ultrasound imaging, providing non-contact, non-invasive backscattering amplitude and phase from a sample. Due to the translucent nature of the tissue, ophthalmic imaging is an ideal space for SDOCT imaging. Structural imaging of the retina has provided new insights into ophthalmic disease ...
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    5. In vivo spectral domain optical coherence tomography volumetric imaging and spectral Doppler velocimetry of early stage embryonic chicken heart development

      In vivo spectral domain optical coherence tomography volumetric imaging and spectral Doppler velocimetry of early stage embryonic chicken heart development
      Progress towards understanding embryonic heart development has been hampered by the inability to image embryonic heart structure and simultaneously measure blood flow dynamics, in vivo. We have developed a spectral domain optical coherence tomography system for in vivo volumetric imaging of the chicken embryo heart. We have also developed a technique called spectral Doppler velocimetry (SDV) for quantitative measurement of blood flow dynamics. In vivo volumetric images and SDV measurements ...
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  2. About Joseph A. Izatt

    Joseph A. Izatt

    Joseph A. Izatt is a Professor of Biomedical Engineering, Associate Professor of Ophthalmology.  Dr. Izatt holds appointments in both the Department of Biomedical Engineering and the Department of Opthalmology. Izatt is also the Director of the Laboratory for Biophotonics in the Fitzpatrick Center for Photonics and Communications.  Izatt's research interest include biomedical optics, spectroscopy, and imaging; laser-tissue interactions; optical and ultrasonic signal processing; novel methods for high-resolution, and minimally invasive medical imaging and tissue characterization.

  3. Quotes

    1. An historic issue with OCT is that the depth resolution is typically several times better than the lateral resolution...If the layers of imaged tissues happen to be horizontal, then they're well defined in the scan. But to extend the full power of OCT for live imaging of tissues throughout the body, a method for overcoming the tradeoff between lateral resolution and depth of imaging was needed.
      In Machine learning increases resolution of eye imaging technology
    2. The use of metal nanoparticles as contrast agents with photothermal OCT technology could lead to a host of potential clinical applications.
      In Heating Up Microscopy