1. Joseph A. Izatt

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    1. Mentioned In 283 Articles

    2. Optimizing Hand-Held Spectral Domain Optical Coherence Tomography Imaging for Neonates, Infants and Children.

      Purpose. To describe age-related considerations and methods to improve hand-held spectral domain optical coherence tomography (HH-SD OCT) imaging of eyes of neonates, infants and children. Methods. Based on calculated optical parameters for neonatal and infant eyes, individualized SD OCT scan parameters were developed for improved imaging in pediatric eyes. Forty-two subjects from 31 weeks post-menstrual age to 1.5 years were imaged with a portable HH-SD OCT system. Images were ...
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    3. Methods, systems and computer program products for characterizing structures based on interferometric phase data

      Methods, systems and computer program products for characterizing structures based on interferometric phase data
      Structure profiles from optical interferometric data can be identified by obtaining a plurality of broadband interferometric optical profiles of a structure as a function of structure depth in an axial direction. Each of the plurality of interferometric optical profiles include a reference signal propagated through a reference path and a sample signal reflected from a sample reflector in the axial direction. An axial position corresponding to at least a portion ...
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    4. Optical Coherence Tomography (OCT) Imaging Systems For Use In Pediatric Ophthalmic Applications And Related Methods And Computer Program Products (Wo 2009/131679)

      Optical Coherence Tomography (OCT) Imaging Systems For Use In Pediatric Ophthalmic Applications And Related Methods And Computer Program Products (Wo 2009/131679)
      Optical coherence tomography (OCT) imaging systems for imaging an eye are provided including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path, the reference arm path having an associated reference arm path length. A sample having an associated sample arm path coupled to the source arm and reference arm paths is provided. A reference arm path ...
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    5. Optical Coherence Tomography (OCT) Imaging Systems Having Adaptable Lens Systems And Related Methods And Computer Program Products (Wo 2009/131701)

      Optical Coherence Tomography (OCT) Imaging Systems Having Adaptable Lens Systems And Related Methods And Computer Program Products (Wo 2009/131701)
      OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal ...
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    6. Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement

      Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement
      Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement Technology Helps Doctors and Researchers Diagnose and Seek Cures for Eye Diseases. CLEVELAND and RESEARCH TRIANGLE PARK, N.C. – Case Western Reserve University and University Hospitals Case Medical Center have granted to Bioptigen, of Research Triangle Park, N.C ., an exclusive intellectual property licensing agreement for Fourier domain optical coherence tomography (FDOCT), an imaging technology ...
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    7. Optical coherence imaging systems having a reduced effective linewidth and methods of using the same

      Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter.
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    8. New biophotonics techniques hold promise but need translation, say researchers at NIH-SPIE 'Bench to Bedside' workshop

      BETHESDA, Maryland, USA, and BELLINGHAM, Washington, USA -- Leading-edge advances such as a revolutionary cardiology treatment and noninvasive optical techniques for studying the brain combined with pragmatic discussions on research focus and funding highlighted a two-day inter-institute workshop last week at the National Institutes of Health (NIH) in Bethesda, Maryland. Approximately 350 preeminent researchers in biophotonics attended the workshop, titled "Optical Diagnostics and Biophotonic Methods from Bench to Bedside." Amir Gandjbakhche ...
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    9. Handheld device detects blindness in infants

      Handheld device detects blindness in infants
      Every year, some 16,000 babies in the U.S. experience loss of vision due to retinopathy of prematurity (RoP), with 400 to 600 becoming legally blind, according to the National Eye Institute. When babies are born prematurely, their retinal blood vessels don't always develop fully, and the abnormal vessels are more prone to leaking and contracting. If that causes the retina to detach, babies can lose some or ...
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    10. Piezoelectric scanning mirrors for endoscopic optical coherence tomography

      A novel piezoelectric scanning mirror design for endoscopic optical coherence tomography (OCT) is presented. OCT is an interferometric technique providing microscopic tomographic sectioning of biological samples with mm-range penetration capability in tissue and is suited for integration with endoscopes using fiber-based light delivery to the sample. The piezoelectric scanning mirror was designed to provide wide-range rapid forwarding-looking scanning of the optical beam at the distal end of a compact catheter ...
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    11. Spectral Domain Optical Coherence Tomography Imaging of Geographic Atrophy Margins

      Objective: To test in vivo whether spectral domain optical coherence tomography (SD-OCT) provides adequate resolution for reproducible measurement of photoreceptor (PR) layer at the margins of geographic atrophy (GA), and if it delineates the relationship between PR layer and retinal pigment epithelium at the margins of GA.Design: Prospective consecutive case series.Participants: Patients with GA secondary to nonneovascular age-related macular degeneration (AMD) identified during routine follow-up at Duke Eye ...
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    12. Imaging systems using unpolarized light and related methods and controllers

      Optical imaging systems are provided including a light source and a depolarizer. The light source is provided in a source arm of the optical imaging system. A depolarizer is coupled to the light source in the source arm of the optical imaging system and is configured to substantially depolarize the light from the light source. Related methods and controllers are also provided.
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    13. Duke given grant to develop eye technology for infants

      A Duke University researcher will receive $100,000 per year for three years to continue her work in developing a tool to check infants for eye problems. Cynthia A. Toth, a professor in Duke Medicine’s Department of Ophthalmology and Biomedical Engineering, has been selected to receive the Hartwell Foundation Biomedical Research award. She is one of 12 individuals from 12 institutions to receive the recognition. Toth is working to ...
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    14. 196-210 of 283 « 1 2 ... 11 12 13 14 15 16 17 18 19 »
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  2. About Joseph A. Izatt

    Joseph A. Izatt

    Joseph A. Izatt is a Professor of Biomedical Engineering, Associate Professor of Ophthalmology.  Dr. Izatt holds appointments in both the Department of Biomedical Engineering and the Department of Opthalmology. Izatt is also the Director of the Laboratory for Biophotonics in the Fitzpatrick Center for Photonics and Communications.  Izatt's research interest include biomedical optics, spectroscopy, and imaging; laser-tissue interactions; optical and ultrasonic signal processing; novel methods for high-resolution, and minimally invasive medical imaging and tissue characterization.

  3. Quotes

    1. An historic issue with OCT is that the depth resolution is typically several times better than the lateral resolution...If the layers of imaged tissues happen to be horizontal, then they're well defined in the scan. But to extend the full power of OCT for live imaging of tissues throughout the body, a method for overcoming the tradeoff between lateral resolution and depth of imaging was needed.
      In Machine learning increases resolution of eye imaging technology
    2. The use of metal nanoparticles as contrast agents with photothermal OCT technology could lead to a host of potential clinical applications.
      In Heating Up Microscopy