1. Joseph A. Izatt

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    1. Mentioned In 282 Articles

    2. Optical coherence refraction tomography

      Optical coherence refraction tomography
      Optical coherence tomography (OCT) is a cross-sectional, micrometre-scale imaging modality with widespread clinical application. Typical OCT systems sacrifice lateral resolution to achieve long depths of focus for bulk tissue imaging, and therefore tend to have better axial than lateral resolution. Such anisotropic resolution can obscure fine ultrastructural features. Furthermore, conventional OCT suffers from refraction-induced image distortions. Here, we introduce optical coherence refraction tomography (OCRT), which extends the superior axial resolution ...
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    3. Duke University Receives NIH Grant for Intraoperative OCT Guidance of Intraocular Surgery

      Duke University Receives NIH Grant for Intraoperative OCT Guidance of Intraocular Surgery
      Duke University Receives a 2019 NIH Grant for $766,562 for Intraoperative OCT Guidance of Intraocular Surgery. The principal investigator is Joseph Izatt. The program began in 2018 and ends in 2023. Below is a summary of the proposed work. This is a resubmission application for a Bioengineering Research Partnership (BRP) which brings together a highly collaborative and experienced team of engineers and ophthalmic surgeons to advance the state of ...
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    4. Ocular anterior chamber blood cell population differentiation using spectroscopic optical coherence tomography

      Ocular anterior chamber blood cell population differentiation using spectroscopic optical coherence tomography
      There is potential clinical significance in identifying cellular responses in the anterior chamber (AC) of the eye, which can indicate hyphema (an accumulation of red blood cells [RBCs]) or aberrant intraocular inflammation (an accumulation of white blood cells [WBCs]). In this work, we developed a spectroscopic OCT analysis method to differentiate between populations of RBCs and subtypes of WBCs, including granulocytes, lymphocytes and monocytes, both in vitro and in ACs ...
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    5. Duke University Receives NIH Grant for Handheld Confocal Scanning Laser Ophthalmoscope for Remote Screening of Diabetic Retinopathy

      Duke University Receives NIH Grant for Handheld Confocal Scanning Laser Ophthalmoscope for Remote Screening of Diabetic Retinopathy
      Duke University Receives a 2019 NIH Grant for $233,465 for Handheld Confocal Scanning Laser Ophthalmoscope for Remote Screening of Diabetic Retinopathy. The principal investigator is Joseph Izatt. The program began in 2019 and ends in 2021. Below is a summary of the proposed work. This is an application for an Exploratory/Developmental Research Grant which brings together a team of engineers and clinician-scientists with expertise in ophthalmic imaging technology ...
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    6. Progress in Multimodal En Face Imaging: feature introduction

      Progress in Multimodal En Face Imaging: feature introduction
      This feature issue contains papers that report on the most recent advances in the field of en face optical coherence tomography (OCT) and of combinations of modalities facilitated by the en face view. Hardware configurations for delivery of en face OCT images are described as well as specific signal and image processing techniques tailored to deliver relevant clinical diagnoses. The value of the en face perspective for enabling multimodality is ...
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    7. Duke University Receives NIH Grant for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Transplantation

      Duke University Receives NIH Grant for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Transplantation
      Duke University Receives a 2019 NIH Grant for $150,000 for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Transplantation. The principal investigator is Joseph Izatt. The program began in 2019 and ends in 2021. Below is a summary of the proposed work. This is an application for an Exploratory/Developmental Research Grant which brings together a team of experts in ophthalmic imaging, surgery and robotics to advance ...
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    8. Advances in Whole-Eye Optical Coherence Tomography Imaging

      Advances in Whole-Eye Optical Coherence Tomography Imaging
      Contemporary anterior segment and retinal optical coherence tomography (OCT) systems only image their particular designated region of the eye and cannot image both areas of the eye at once. This separation is due to the differences in optical system design needed to properly image the front or back of the eye and also due to limitations in the imaging depth of current commercial OCT systems. More recently, research and commercial ...
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    9. Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope

      Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope
      Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope are disclosed herein. According to an aspect, a system includes first and second eyepieces. The system includes a display having first and second display portions, configured to display first images in the first display portion, and configured to display second images in the second display portion. The first image and the second image are projected ...
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    10. Depth-Based, Motion-Stabilized Colorization of Microscope-Integrated Optical Coherence Tomography Volumes for Microscope-Independent Microsurgery

      Depth-Based, Motion-Stabilized Colorization of Microscope-Integrated Optical Coherence Tomography Volumes for Microscope-Independent Microsurgery
      Purpose : We develop and assess the impact of depth-based, motion-stabilized colorization (color) of microscope-integrated optical coherence tomography (MIOCT) volumes on microsurgical performance and ability to interpret surgical volumes. Methods : Color was applied in real-time as gradients indicating axial position and stabilized based on calculated center of mass. In a test comparing colorization versus grayscale visualizations of prerecorded intraoperative volumes from human surgery, ophthalmologists ( N = 7) were asked to identify retinal ...
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    11. Feature Issue of Biomedical Optics Express: Progress in Multimodal En-Face Imaging Manuscript Deadline September 15, 2018

      Feature Issue of Biomedical Optics Express: Progress in Multimodal En-Face Imaging Manuscript Deadline September 15, 2018
      Biomedical Optics Express welcomes submissions to a feature issue on "Progress in Multimodal En-Face Imaging". Multimodal optical imaging certainly enriches the amount of information that can be retrieved from biological tissue. For this purpose, many different approaches have been combined, including optical coherence tomography (OCT), microscopy, scanning laser ophthalmoscopy (SLO), fluorescence imaging, multi-photon imaging, Raman spectroscopy, photoacoustics, and many more. This year marks 20 years from the publication of a ...
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    12. Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning

      Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning
      The present invention is directed to a method and system for improved aiming during Optical Coherence Tomography (OCT) on young children and those unable to cooperate with OCT imaging by synchronization with retinal birefringence scanning (RBS). OCT is performed without knowing whether or not the subject is looking at the intended target. The present invention combines OCT retinal imaging, such as, but not limited to, time domain OCT, SDOCT, or ...
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    13. Feature of the Week 06/24/2018: Duke University Researchers Show Exciting Advances in Live OCT Volumes in Immersive Virtual Reality

      Feature of the Week 06/24/2018: Duke University Researchers Show Exciting Advances in Live OCT Volumes in Immersive Virtual Reality
      Virtual reality (VR) head-mounted displays are an attractive technology for viewing intrasurgical optical coherence tomography (OCT) volumes because they liberate surgeons from microscope oculars. We demonstrate real-time, interactive viewing of OCT volumes in a commercial HTC Vive immersive VR system using previously reported ray casting techniques. Furthermore, we show interactive manipulation and sectioning of volumes using handheld controllers and guidance of mock surgical procedures in porcine eyes exclusively within VR ...
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    14. Real-time visualization and interaction with static and live optical coherence tomography volumes in immersive virtual reality

      Real-time visualization and interaction with static and live optical coherence tomography volumes in immersive virtual reality
      Virtual reality (VR) head-mounted displays are an attractive technology for viewing intrasurgical optical coherence tomography (OCT) volumes because they liberate surgeons from microscope oculars. We demonstrate real-time, interactive viewing of OCT volumes in a commercial HTC Vive immersive VR system using previously reported ray casting techniques. Furthermore, we show interactive manipulation and sectioning of volumes using handheld controllers and guidance of mock surgical procedures in porcine eyes exclusively within VR ...
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    15. 1-15 of 282 1 2 3 4 ... 17 18 19 »
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  2. About Joseph A. Izatt

    Joseph A. Izatt

    Joseph A. Izatt is a Professor of Biomedical Engineering, Associate Professor of Ophthalmology.  Dr. Izatt holds appointments in both the Department of Biomedical Engineering and the Department of Opthalmology. Izatt is also the Director of the Laboratory for Biophotonics in the Fitzpatrick Center for Photonics and Communications.  Izatt's research interest include biomedical optics, spectroscopy, and imaging; laser-tissue interactions; optical and ultrasonic signal processing; novel methods for high-resolution, and minimally invasive medical imaging and tissue characterization.

  3. Quotes

    1. The use of metal nanoparticles as contrast agents with photothermal OCT technology could lead to a host of potential clinical applications.
      In Heating Up Microscopy