1. Johns Hopkins University

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    1. Mentioned In 454 Articles

    2. Johns Hopkins University Receives NIH Grant for Enabling technology for image-guided robot-assisted sub-retinal injections

      Johns Hopkins University Receives NIH Grant for Enabling technology for image-guided robot-assisted sub-retinal injections
      ...in the integration of man, machine and computer for the performance of unprecedented microsurgical maneuvers. Johns Hopkins University Receives a 2021 NIH Grant for $468,446 for Enabling technology for image-guided robot...
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    3. Optical Coherence Tomography Angiography-Derived Flux As a Measure of Physiological Changes in Retinal Capillary Blood Flow

      Optical Coherence Tomography Angiography-Derived Flux As a Measure of Physiological Changes in Retinal Capillary Blood Flow
      Purpose: To compare optical coherence tomography angiography (OCTA)-derived flux with conventional OCTA measures of retinal vascular density in assessment of physiological changes in retinal blood flow. Methods: Healthy subjects were recruited, and 3 3-mm2 fovea-centered scans were acquired using commercially available swept-source OCTA (SS-OCTA) while participants were breathing room air, 100% O2, or 5% CO2. Retinal perfusion was quantified using vessel area density (VAD) and vessel skeleton density (VSD ...
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    4. CNN-based CP-OCT sensor integrated with a subretinal injector for retinal boundary tracking and injection guidance

      CNN-based CP-OCT sensor integrated with a subretinal injector for retinal boundary tracking and injection guidance
      Significance: Subretinal injection is an effective way of delivering transplant genes and cells to treat many degenerative retinal diseases. However, the technique requires high-dexterity and microscale precision of experienced surgeons, who have to overcome the physiological hand tremor and limited visualization of the subretinal space. Aim: To automatically guide the axial motion of microsurgical tools (i.e., a subretinal injector) with microscale precision in real time using a fiber-optic common-path ...
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    5. Stabilizing the phase of swept-source optical coherence tomography by a wrapped Gaussian mixture model

      Stabilizing the phase of swept-source optical coherence tomography by a wrapped Gaussian mixture model
      The phase of an optical coherence tomography (OCT) signal carries critical information about particle micro-displacements. However, swept-source OCT (SSOCT) suffers from phase instability problems due to trigger jitters from the swept source. In this Letter, a wrapped Gaussian mixture model (WGMM) is proposed to stabilize the phase of SSOCT systems. A closed-form iteration solution of the WGMM is derived using the expectation-maximization algorithm. Necessary approximations are made for real-time graphic ...
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    6. Processing-Aware Real-Time Rendering for Optimized Tissue Visualization in Intraoperative 4D OCT

      Processing-Aware Real-Time Rendering for Optimized Tissue Visualization in Intraoperative 4D OCT
      Intraoperative Optical Coherence Tomography (iOCT) has advanced in recent years to provide real-time high resolution volumetric imaging for ophthalmic surgery. It enables real-time 3D feedback during precise surgical maneuvers. Intraoperative 4D OCT generally exhibits lower signal-to-noise ratio compared to diagnostic OCT and visualization is complicated by instrument shadows occluding retinal tissue. Additional constraints of processing data rates upwards of 6GB/s create unique challenges for advanced visualization of 4D OCT ...
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    7. Retinal racemose hemangioma (retinal arteriovenous communication) diagnosed and managed with multimodal imaging

      Retinal racemose hemangioma (retinal arteriovenous communication) diagnosed and managed with multimodal imaging
      Purpose: Retinal racemose hemangioma (RRH) is a rare congenital abnormality of the retinal vasculature with a variety of secondary manifestations that can cause vision loss, including macular edema. This report aims to demonstrate the utility of swept-source optical coherence tomography angiography (SS-OCTA) in further characterizing this abnormality. Methods: Case report with multimodal imaging including SS-OCTA. Results: A 56-year-old woman with blurred vision was diagnosed macular edema secondary to RRH. Localization ...
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    8. Deep Learning in Biomedical Optics

      Deep Learning in Biomedical Optics
      This article reviews deep learning applications in biomedical optics with a particular emphasis on image formation. The review is organized by imaging domains within biomedical optics and includes microscopy, fluorescence lifetime imaging, in vivo microscopy, widefield endoscopy, optical coherence tomography, photoacoustic imaging, diffuse tomography, and functional optical brain imaging. For each of these domains, we summarize how deep learning has been applied and highlight methods by which deep learning can ...
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    9. Cognitive decline in older adults: What can we learn from optical coherence tomography (OCT)-based retinal vascular imaging?

      Cognitive decline in older adults: What can we learn from optical coherence tomography (OCT)-based retinal vascular imaging?
      Introduction: Accumulated vascular damage contributes to the onset and progression of vascular dementia and possibly to Alzheimer's disease. Here we evaluate the feasibility and utility of using retinal imaging of microvascular markers to identify older adults at risk of cognitive disease. Methods: The "Eye Determinants of Cognition" (EyeDOC) study recruited a biracial, population-based sample of participants from two sites: Jackson, MS, and Washington Co, MD. Optical coherence tomographic angiography ...
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    10. The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies

      The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies
      Objective: To update the consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results, thus revising the previously published Advised Protocol for OCT Study Terminology and Elements (APOSTEL) recommendations. Methods: To identify studies reporting quantitative OCT results, we performed a PubMed search for the terms "quantitative" and "optical coherence tomography" from 2015 to 2017. Corresponding authors of the identified publications were invited to provide feedback on the initial ...
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    11. Choroidal Vascular Changes in Acute Idiopathic Maculopathy as Demonstrated by Multimodal Imaging including Optical Coherence Tomography Angiography

      Choroidal Vascular Changes in Acute Idiopathic Maculopathy as Demonstrated by Multimodal Imaging including Optical Coherence Tomography Angiography
      Purpose . To present a case of acute idiopathic maculopathy (AIM) and illustrate primary choroidal perfusion defect using multimodal imaging. Case Description . We report a case of a 24-year-old man with a paracentral scotoma of the right eye and recent flu-like illness. The patient was found to have a unilateral ovoid-shaped, placoid lesion just inferior to the fovea. Multimodal imaging confirmed findings most consistent with a diagnosis of acute idiopathic maculopathy ...
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    12. Real-time tool to layer distance estimation for robotic subretinal injection using intraoperative 4D OCT

      Real-time tool to layer distance estimation for robotic subretinal injection using intraoperative 4D OCT
      The emergence of robotics could enable ophthalmic microsurgical procedures that were previously not feasible due to the precision limits of manual delivery, for example, targeted subretinal injection. Determining the distance between the needle tip, the internal limiting membrane (ILM), and the retinal pigment epithelium (RPE) both precisely and reproducibly is required for safe and successful robotic retinal interventions. Recent advances in intraoperative optical coherence tomography (iOCT) have opened the path ...
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    13. Johns Hopkins University Receives NIH Grant for Artificial Intelligence Optical Coherence Tomography Guided Deep Anterior Lamellar Kerotoplasty (Auto-Dalk)

      Johns Hopkins University Receives NIH Grant for Artificial Intelligence Optical Coherence Tomography Guided Deep Anterior Lamellar Kerotoplasty (Auto-Dalk)
      ...he manually performed trephine cutting and Big Bubble pneumodissection.

      Johns Hopkins University Receives a 2021 NIH Grant for $409,997 for Artificial Intelligence Optical Coher...

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    14. Standardization of optical coherence tomography angiography nomenclature in retinal vascular diseases: first survey results

      Standardization of optical coherence tomography angiography nomenclature in retinal vascular diseases: first survey results
      Purpose: To develop a consensus nomenclature for optical coherence tomography angiography (OCTA) findings in retinal vascular diseases. Design: Online survey using Delphi Method SUBJECTS, PARTICIPANTS AND/OR CONTROLS: Members of The Retina Society, European Society of Retina Specialists (EURETINA) and the Japanese Retina and Vitreous Society (JRVS). Methods, intervention, or testing: An online questionnaire on OCTA terminology in retinal vascular diseases was sent to members of The Retina Society, EURETINA ...
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    15. 1-15 of 454 1 2 3 4 ... 29 30 31 »
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  2. About Johns Hopkins University

    Johns Hopkins University

    John Hopkins University mission is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.  Hopkins now uses one overarching name - Johns Hopkins Medicine -to identify its whole medical enterprise. This $4 billion virtual organization unites the physicians and scientists of The Johns Hopkins University School of Medicine with the health professionals and facilities that make up the broad Johns Hopkins Health System.  The Wilmer Eye Institute at Johns Hopkins has long been recognized for bringing together ophthalmologists consistently ranked by their peers as among the finest internationally, with a specially trained and highly experienced team of nurses cited by patients for their knowledge, responsiveness, and sensitivity. Johns Hopkins Multiple Sclerosis Center is one of the largest clinical and research MS centers in the world.