1. Johns Hopkins University

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    1. Mentioned In 409 Articles

    2. In Vivo Characterization of the Deformation of the Human Optic Nerve Head Using Optical Coherence Tomography and Digital Volume Correlation

      Explore ScienceDirect Ophthalmology
      In Vivo Characterization of the Deformation of the Human Optic Nerve Head Using Optical Coherence Tomography and Digital Volume Correlation
      We developed a method to measure the 3-dimensional (3D) strain field in the optic nerve head (ONH) in vivo between two intraocular pressures (IOP). Radial optical coherence tomography (OCT) scans were taken of the ONH of 5 eyes from 5 glaucoma patients before and after IOP-lowering surgery and from 5 eyes from 3 glaucoma suspect patients before and after raising IOP by wearing tight-fitting swimming goggles. Scans taken at higher ...
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      Mentions: Johns Hopkins University

    4. OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes

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      OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes
      Purpose To assess anterior scleral canal opening (ASCO) offset relative to Bruchs membrane opening (BMO) (ASCO/BMO offset) so as to determine neural canal direction, obliqueness, and minimum cross-sectional area (NCMCA) in 362 healthy eyes. Design Cross-sectional study Methods After OCT optic nerve head (ONH) and retinal nerve fiber layer thickness (RNFLT) imaging, BMO and ASCO were manually segmented and planes, centroids, size and shape were calculated. Neural canal direction ...
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      Mentions: Johns Hopkins University Mount Sinai School of Medicine University of Alabama

    5. Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: An international study

      Explore Wiley Online Library Neurology , Ophthalmology
      Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: An international study
      Objective To determine the optimal thresholds for intereye differences in retinal nerve fiber and ganglion cell + inner plexiform layer thicknesses for identifying unilateral optic nerve lesions in multiple sclerosis. Current international diagnostic criteria for multiple sclerosis do not include the optic nerve as a lesion site despite frequent involvement. Optical coherence tomography detects retinal thinning associated with optic nerve lesions. Methods In this multicenter international study at 11 sites, optical ...
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      Mentions: Peter A. Calabresi Johns Hopkins University Laura J. Balcer

    6. Ultralow-voltage electrothermal MEMS based fiber-optic scanning probe for forward-viewing endoscopic OCT

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      Ultralow-voltage electrothermal MEMS based fiber-optic scanning probe for forward-viewing endoscopic OCT
      We report an ultralow-voltage, electrothermal (ET) micro-electro-mechanical system (MEMS) based probe for forward-viewing endoscopic optical coherence tomography (OCT) imaging. The fully assembled probe has a diameter of 5.5 mm and a length of 55 mm, including the imaging optics and a 40 mm long fiber-optic cantilever attached on a micro-platform of the bimorph ET MEMS actuator. The ET MEMS actuator provides a sufficient mechanical actuation force as well as ...
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      Mentions: Johns Hopkins University University of Florida Huikai K. Xie

    7. Subretinal pseudocyst: A novel optical coherence tomography finding in age-related macular degeneration

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      Subretinal pseudocyst: A novel optical coherence tomography finding in age-related macular degeneration
      Purpose: To report the presence of a new structural optical coherence tomography finding, namely, subretinal pseudocysts, in a patient affected by age-related macular degeneration. Methods: Case report including multimodal imaging discussion. Case Report: We report a case of a 77-year-old woman affected by age-related macular degeneration from 7years. Best corrected visual acuity was counting fingers and 20/40 in the right and left eye, respectively. The left eye was affected ...
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      Mentions: Johns Hopkins University University of Iowa Giuseppe Querques

    8. Sensitivity and Specificity of Potential Diagnostic Features Detected Using Fundus Photography, Optical Coherence Tomography, and Fluorescein Angiography for Polypoidal Choroidal Vasculopathy

      Explore The JAMA Network Ophthalmology
      Sensitivity and Specificity of Potential Diagnostic Features Detected Using Fundus Photography, Optical Coherence Tomography, and Fluorescein Angiography for Polypoidal Choroidal Vasculopathy
      Importance The use of indocyanine green angiography (ICGA) is a criterion standard for diagnosing polypoidal choroidal vasculopathy (PCV), an endemic and common cause of vision loss in Asian and African individuals that also presents in white individuals. However, the use of ICGA is expensive, invasive, and not always available at clinical centers. Therefore, knowing the value of certain features detected using fundus photography (FP), optical coherence tomography (OCT), and fluorescein ...
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      Mentions: Johns Hopkins University Prince of Songkla University

    9. Optimal Inter‐Eye Difference Thresholds by OCT in MS: An International Study

      Explore Wiley Online Library Neurology , Ophthalmology
      Optimal Inter‐Eye Difference Thresholds by OCT in MS: An International Study
      Objective To determine the optimal thresholds for inter‐eye differences in retinal nerve fiber and ganglion cell+inner plexiform layer thicknesses for identifying unilateral optic nerve lesions in multiple sclerosis. Background Current international diagnostic criteria for multiple sclerosis do not include the optic nerve as a lesion site despite frequent involvement. Optical coherence tomography detects retinal thinning associated with optic nerve lesions. Methods In this multi‐center international study at ...
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      Mentions: Peter A. Calabresi Johns Hopkins University Laura J. Balcer

    10. Optical Coherence Tomography Assessment of the Cornea During Corneal Swelling Should the Term “Descemet Membrane Folds” Be Reconsidered?

      Explore LWW Online Ophthalmology
      Optical Coherence Tomography Assessment of the Cornea During Corneal Swelling Should the Term “Descemet Membrane Folds” Be Reconsidered?
      Purpose: Previous work has suggested that Descemet membrane (DM) folds arise in response to corneal swelling . However, their origin has not been closely explored. In this study, we used optical coherence tomography to evaluate whether DM folds arise secondary to folds in the middle stroma. Methods: Serial optical coherence tomography images of donor cornea pairs in deionized water were taken for each of the following corneal manipulations: 1) untreated, 2 ...
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      Mentions: Johns Hopkins University

    11. Johns Hopkins University Receives NIH Grant for Intra-Operative, Label-Free Detention of Brain Cancer infiltration with Quantitative Optical Imaging

      Explore Optical Coherence Tomography News Neurology , Funding
      Johns Hopkins University Receives NIH Grant for Intra-Operative, Label-Free Detention of Brain Cancer infiltration with Quantitative Optical Imaging
      ...he brain, oral, cervical and GI cancers), thereby improving patient survival.

      Johns Hopkins University Receives a 2019 NIH Grant for $589,760 for Intra-Operative, Label-Free Detention of B...

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      Mentions: Johns Hopkins University National Institutes of Health Xingde Li

    12. Factors Influencing Optical Coherence Tomography Peripapillary Choroidal Thickness: A Multicenter Study

      Explore IOVS Journal Ophthalmology
      Factors Influencing Optical Coherence Tomography Peripapillary Choroidal Thickness: A Multicenter Study
      Purpose : To quantify peripapillary choroidal thickness (PCT) and the factors that influence it in healthy participants who represent the racial and ethnic composition of the U.S. population. Methods : A total of 362 healthy participants underwent optical coherence tomography (OCT) enhanced depth imaging of the optic nerve head with a 24 radial B-scan pattern aligned to the fovea to Bruch's membrane opening axis. Bruch's membrane, anterior scleral canal ...
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      Mentions: Johns Hopkins University Mount Sinai School of Medicine University of Alabama

    15. Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease

      Explore Home - Springer Ophthalmology
      Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease
      Purpose Automated spectral domain optical coherence tomography (SD-OCT) segmentation algorithms currently do not perform well in segmenting individual intraretinal layers in eyes with Stargardt disease (STGD). We compared selective B-scan segmentation strategies for generating mean retinal layer thickness and preserved area data from SD-OCT scans in patients with STGD1. Methods Forty-five eyes from 40 Stargardt patients were randomly selected from the ongoing Natural History of the Progression of Atrophy Secondary ...
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      Mentions: Johns Hopkins University University College London Hendrik P. N. Scholl

    16. Retinal layer parcellation of optical coherence tomography images: Data resource for Multiple Sclerosis and Healthy Controls

      Explore ScienceDirect Neurology , Ophthalmology
      Retinal layer parcellation of optical coherence tomography images: Data resource for Multiple Sclerosis and Healthy Controls
      This paper presents optical coherence tomography (OCT) images of the human retina and manual delineations of eight retinal layers. The data includes 35 human retina scans acquired on a Spectralis OCT system (Heidelberg Engineering, Heidelberg, Germany), 14 of which are healthy controls (HC) and 21 have a diagnosis of multiple sclerosis (MS). The provided data includes manually delineation of eight retina layers, which were independently reviewed and edited. The data ...
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      Mentions: Peter A. Calabresi Johns Hopkins University Heidelberg Engineering
    17. 1-15 of 409 1 2 3 4 ... 26 27 28 »
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  4. About Johns Hopkins University

    Johns Hopkins University

    John Hopkins University mission is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.  Hopkins now uses one overarching name - Johns Hopkins Medicine -to identify its whole medical enterprise. This $4 billion virtual organization unites the physicians and scientists of The Johns Hopkins University School of Medicine with the health professionals and facilities that make up the broad Johns Hopkins Health System.  The Wilmer Eye Institute at Johns Hopkins has long been recognized for bringing together ophthalmologists consistently ranked by their peers as among the finest internationally, with a specially trained and highly experienced team of nurses cited by patients for their knowledge, responsiveness, and sensitivity. Johns Hopkins Multiple Sclerosis Center is one of the largest clinical and research MS centers in the world.

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