1. Johns Hopkins University

    0 Comments Leave a Comment

    1-15 of 421 1 2 3 4 ... 26 27 28 »

    1. Mentioned In 421 Articles

    2. Ultra-sensitive optical coherence elastography using a high-dynamic-range force loading scheme for cervical rigidity assessment

      Explore OSA | OSA Publishing Gynecology
      Ultra-sensitive optical coherence elastography using a high-dynamic-range force loading scheme for cervical rigidity assessment
      An ultra-sensitive, wide-range force loading scheme is proposed for compression optical coherence elastography (OCE) that allows for the quantitative analysis of cervical tissue elasticity ex vivo . We designed a force loading apparatus featuring a water sink for minuscule incremental loading through a volume-controlled water droplet, from which the Youngs modulus can be calculated by fitting the stress-strain curve. We validated the performance of the proposed OCE system on homogenous agar ...
      Read Full Article
      Mentions: Johns Hopkins University Xingde Li

    3. Robust, accurate depth-resolved attenuation characterization in optical coherence tomography

      Explore OSA | OSA Publishing
      Robust, accurate depth-resolved attenuation characterization in optical coherence tomography
      Depth-resolved optical attenuation coefficient is a valuable tissue parameter that complements the intensity-based structural information in optical coherent tomography (OCT) imaging. Herein we systematically analyzed the under- and over-estimation bias of existing depth-resolved methods when applied to real biological tissues, and then proposed a new algorithm that remedies these issues and accommodates general OCT data that contain incomplete decay and noise floor, thereby affording consistent estimation accuracy for practical biological ...
      Read Full Article
      Mentions: Johns Hopkins University Columbia University Yanmei Liang

    4. Demonstration of Optical Coherence Tomography Guided Big Bubble Technique for Deep Anterior Lamellar Keratoplasty (DALK)

      Explore MDPI Open Access Journals Platform Ophthalmology
      Demonstration of Optical Coherence Tomography Guided Big Bubble Technique for Deep Anterior Lamellar Keratoplasty (DALK)
      Deep anterior lamellar keratoplasty (DALK) is a highly challenging procedure for cornea transplant that involves removing the corneal layers above Descemets membrane (DM). This is achieved by a big bubble technique where a needle is inserted into the stroma of the cornea down to DM and the injection of either air or liquid. DALK has important advantages over penetrating keratoplasty (PK) including lower rejection rate, less endothelial cell loss, and ...
      Read Full Article
      Mentions: University of Maryland Johns Hopkins University

    5. Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases

      Explore MDPI Open Access Journals Platform Ophthalmology
      Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases
      Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies. In this review, we provide an overview of the evolution of OCTA technology, compare the specifications of various OCTA devices, and summarize key findings from published OCTA studies in ...
      Read Full Article
      Mentions: Johns Hopkins University

    6. Optical coherence tomography using physical domain data compression to achieve MHz A-scan rates

      Explore OSA | OSA Publishing
      Optical coherence tomography using physical domain data compression to achieve MHz A-scan rates
      The three-dimensional volumetric imaging capability of optical coherence tomography (OCT) leads to the generation of large amounts of data, which necessitates high speed acquisition followed by high dimensional image processing and visualization. This signal acquisition and processing pipeline demands high A-scan rates on the front end, which has driven researchers to push A-scan acquisition rates into the MHz regime. To this end, the optical time-stretch approach uses a mode locked ...
      Read Full Article
      Mentions: Johns Hopkins University Boston University

    7. Macular Ganglion Cell and Inner Plexiform Layer Thickness Is More Strongly Associated With Visual Function in Multiple Sclerosis Than Bruch Membrane Opening–Minimum Rim Width or Peripapillary Retinal Nerve Fiber Layer Thicknesses

      Explore LWW Online Neurology , Ophthalmology
      Macular Ganglion Cell and Inner Plexiform Layer Thickness Is More Strongly Associated With Visual Function in Multiple Sclerosis Than Bruch Membrane Opening–Minimum Rim Width or Peripapillary Retinal Nerve Fiber Layer Thicknesses
      ...pondence to Shiv Saidha, MBBCh, MD, MRCPI, Neurology Division of Neuroimmunology and Neurological Infections, Johns Hopkins Hospital, 600N. Wolfe Street, Baltimore, MD 21287; E-mail: ssaidha2@jhmi.edu This study was fund...
      Read Full Article
      Mentions: Peter A. Calabresi Johns Hopkins University National Institutes of Health

    8. Excess mucus viscosity and airway dehydration impact COPD airway clearance

      Explore European Respiratory Journal Pulmonology
      Excess mucus viscosity and airway dehydration impact COPD airway clearance
      The mechanisms by which cigarette smoking impairs airway mucus clearance are not well understood. We recently established a ferret model of cigarette smoke-induced chronic obstructive pulmonary disease (COPD) exhibiting chronic bronchitis. We investigated the effects of cigarette smoke on mucociliary transport (MCT). Adult ferrets were exposed to cigarette smoke for 6 months, with in vivo mucociliary clearance (MCC) measured by Tc-labeled DTPA (Tc-DTPA) retention. Excised tracheae were imaged with micro-optical ...
      Read Full Article
      Mentions: Guillermo J. Tearney Johns Hopkins University Massachusetts General Hospital

    9. Intraoperative Speckle Variance Optical Coherence Tomography for Tissue Temperature Monitoring During Cutaneous Laser Therapy

      Explore IEEE Xplore Dermatology
      Intraoperative Speckle Variance Optical Coherence Tomography for Tissue Temperature Monitoring During Cutaneous Laser Therapy
      Background: Tissue temperature monitoring during cutaneous laser therapy can lead to safer and more effective treatments. In this study, we investigate the use of speckle variance optical coherence tomography (svOCT) to monitor real-time temperature changes in the excised human skin tissue sample during laser irradiation. Methods: To accomplish this, we combined the pulse laser system with a reference-based svOCT system. To calibrate the svOCT, the ex-vivo human skin samples from ...
      Read Full Article
      Mentions: Johns Hopkins University Jin U. Kang

    10. Optical coherence tomography and multiple sclerosis: Update on clinical application and role in clinical trials

      Explore SAGE Journals Neurology , Ophthalmology
      Optical coherence tomography and multiple sclerosis: Update on clinical application and role in clinical trials
      Optical coherence tomography (OCT) has emerged as a fast, non-invasive, inexpensive, high-resolution imaging technique in multiple sclerosis (MS). Retinal layer quantification by OCT facilitates a window into not only local retinal pathology but also global neurodegenerative processes, recognised to be the principal substrates of disability accumulation in MS. While OCT measures in MS have been demonstrated to reflect visual function, inflammatory activity outside of the visual pathways, disability measures including ...
      Read Full Article
      Mentions: Johns Hopkins University Cleveland Clinic

    11. Retinal Vascular Changes on Optical Coherence Tomography Angiography and Ultra-widefield Fluorescein Angiography in Patients With Chronic Leukemia

      Explore SAGE Journals Ophthalmology
      Retinal Vascular Changes on Optical Coherence Tomography Angiography and Ultra-widefield Fluorescein Angiography in Patients With Chronic Leukemia
      Purpose: This article describes pathological retinal vascular changes on multimodal imaging in patients with chronic leukemia. Methods: A prospective, observational study was conducted. Patients with chronic leukemia and concurrent leukocytosis were recruited from a tertiary-referral, academic medical center. Eligible patients received complete ophthalmic examinations and multimodal retinal imaging: spectral-domain optical coherence tomography (SD-OCT), optical coherence tomography angiography (OCTA), and ultra-widefield fluorescein angiography (UWF FA). Results: Six patients (11 eyes) were ...
      Read Full Article
      Mentions: Johns Hopkins University

    13. AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography

      Explore Clinical Cancer Research Neurology
      AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography
      Purpose: In glioma surgery, it is critical to maximize tumor resection without compromising adjacent non-cancerous brain tissue. Optical Coherence Tomography (OCT) is a non-invasive, label-free, real-time, high-resolution imaging modality that has been explored for glioma infiltration detection. Here we report a novel artificial intelligence (AI) assisted method for automated, real-time, in situ detection of glioma infiltration at high spatial resolution. Experimental Design: Volumetric OCT datasets were intraoperatively obtained from resected ...
      Read Full Article
      Mentions: Johns Hopkins University Texas A&M University Javier A. Jo

    14. In Vivo Characterization of the Deformation of the Human Optic Nerve Head Using Optical Coherence Tomography and Digital Volume Correlation

      Explore ScienceDirect Ophthalmology
      In Vivo Characterization of the Deformation of the Human Optic Nerve Head Using Optical Coherence Tomography and Digital Volume Correlation
      We developed a method to measure the 3-dimensional (3D) strain field in the optic nerve head (ONH) in vivo between two intraocular pressures (IOP). Radial optical coherence tomography (OCT) scans were taken of the ONH of 5 eyes from 5 glaucoma patients before and after IOP-lowering surgery and from 5 eyes from 3 glaucoma suspect patients before and after raising IOP by wearing tight-fitting swimming goggles. Scans taken at higher ...
      Read Full Article
      Mentions: Johns Hopkins University

    16. OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes

      Explore ScienceDirect Ophthalmology
      OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes
      Purpose To assess anterior scleral canal opening (ASCO) offset relative to Bruchs membrane opening (BMO) (ASCO/BMO offset) so as to determine neural canal direction, obliqueness, and minimum cross-sectional area (NCMCA) in 362 healthy eyes. Design Cross-sectional study Methods After OCT optic nerve head (ONH) and retinal nerve fiber layer thickness (RNFLT) imaging, BMO and ASCO were manually segmented and planes, centroids, size and shape were calculated. Neural canal direction ...
      Read Full Article
      Mentions: Johns Hopkins University Mount Sinai School of Medicine University of Alabama
    17. 1-15 of 421 1 2 3 4 ... 26 27 28 »
  1. Search:

  2. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology

    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents

    3. Technology:

      Broadband Sources, Probes, Tunable Sources

    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks

  4. About Johns Hopkins University

    Johns Hopkins University

    John Hopkins University mission is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.  Hopkins now uses one overarching name - Johns Hopkins Medicine -to identify its whole medical enterprise. This $4 billion virtual organization unites the physicians and scientists of The Johns Hopkins University School of Medicine with the health professionals and facilities that make up the broad Johns Hopkins Health System.  The Wilmer Eye Institute at Johns Hopkins has long been recognized for bringing together ophthalmologists consistently ranked by their peers as among the finest internationally, with a specially trained and highly experienced team of nurses cited by patients for their knowledge, responsiveness, and sensitivity. Johns Hopkins Multiple Sclerosis Center is one of the largest clinical and research MS centers in the world.

  5. Related Topics

    1. Common-path optical coherence tomography with side-viewing bare fiber probe for endoscopic optical coherence tomography
      132 articles also mentioned Jin U. Kang
    2. Optical coherence tomography and disease subtype in multiple sclerosis
      67 articles also mentioned Peter A. Calabresi
    3. A motion compensated fiber optic confocal microscope based on common-path optical coherent tomography distance sensor
      43 articles also mentioned Yong Huang
    4. High-resolution OCT balloon imaging catheter with astigmatism correction
      38 articles also mentioned Xingde Li
    5. Signal-to-noise ratio analysis of all-fiber common-path optical coherence tomography
      32 articles also mentioned Xuan Liu