1. Jiefeng Xi

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    1-15 of 15
    1. Mentioned In 15 Articles

    2. AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography

      AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography
      Purpose: In glioma surgery, it is critical to maximize tumor resection without compromising adjacent non-cancerous brain tissue. Optical Coherence Tomography (OCT) is a non-invasive, label-free, real-time, high-resolution imaging modality that has been explored for glioma infiltration detection. Here we report a novel artificial intelligence (AI) assisted method for automated, real-time, in situ detection of glioma infiltration at high spatial resolution. Experimental Design: Volumetric OCT datasets were intraoperatively obtained from resected ...
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    3. Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging

      Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging
      We investigated the optimal operational conditions for utilizing a broadband supercontinuum (SC) source in a portable 800 nm spectral-domain (SD) endoscopic OCT system to enable high resolution, high-sensitivity, and high-speed imaging in vivo . A SC source with a 3-dB bandwidth of 246 nm was employed to obtain an axial resolution of 2.7 m (in air) and an optimal detection sensitivity of 107 dB with an imaging speed up to ...
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    4. Detection of human brain cancer infiltration ex vivo and in vivo using quantitative optical coherence tomography

      Detection of human brain cancer infiltration ex vivo and in vivo using quantitative optical coherence tomography
      More complete brain cancer resection can prolong survival and delay recurrence. However, it is challenging to distinguish cancer from noncancer tissues intraoperatively, especially at the transitional, infiltrative zones. This is especially critical in eloquent regions (for example, speech and motor areas). This study tested the feasibility of label-free, quantitative optical coherence tomography (OCT) for differentiating cancer from noncancer in human brain tissues. Fresh ex vivo human brain tissues were obtained ...
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    5. An all-fiber-optic endoscopy platform for simultaneous OCT and fluorescence imaging

      An all-fiber-optic endoscopy platform for simultaneous OCT and fluorescence imaging
      We present an all-fiber-optically based endoscope platform for simultaneous optical coherence tomography (OCT) and fluorescence imaging. This design entails the use of double-clad fiber (DCF) in the endoscope for delivery of OCT source and fluorescence excitation light while collecting the backscattered OCT signal through the single-mode core and fluorescence emission through the large inner cladding of the DCF. Circumferential beam scanning was performed by rotating a 45 reflector using a ...
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    6. Robust High-Resolution Fine OCT Needle for Side-Viewing Interstitial Tissue Imaging

      Robust High-Resolution Fine OCT Needle for Side-Viewing Interstitial Tissue Imaging
      Fine optical coherence tomography (OCT) imaging needles that can be integrated with a standard biopsy needle have been developed with a new optics design to improve the optical quality and mechanical robustness, where a fiber-optic lens (that is spliced to a single-mode fiber) and a microreflector are encased within a microglass tube. The design also minimizes the cylindrical lens effect induced by the glass tube and eases the needle assembly ...
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  2. About Jiefeng Xi

    Jiefeng Xi

    Jiefeng Xi Principle Engineer at Micro-Tech (Nanjing) Co. Ltd. Dr. Xi finished his PhD at Johns Hopkins University in July 2014 studying under Professor Xingde Li.