1. Jiawen Li

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    1. Mentioned In 18 Articles

    2. Ultrathin monolithic 3D printed optical coherence tomography endoscopy for preclinical and clinical use

      Explore Nature Publishing Group Probes
      Ultrathin monolithic 3D printed optical coherence tomography endoscopy for preclinical and clinical use
      Preclinical and clinical diagnostics increasingly rely on techniques to visualize internal organs at high resolution via endoscopes. Miniaturized endoscopic probes are necessary for imaging small luminal or delicate organs without causing trauma to tissue. However, current fabrication methods limit the imaging performance of highly miniaturized probes, restricting their widespread application. To overcome this limitation, we developed a novel ultrathin probe fabrication technique that utilizes 3D microprinting to reliably create side-facing ...
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      Mentions: Robert A. McLaughlin Rodney W. Kirk Jiawen Li

    3. Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes

      Explore Nature Publishing Group Probes
      Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes
      Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with both complex optical function and dimensions comparable to the optical fibre diameter. Recently, major advances in two-photon direct laser writing have enabled 3D printing of arbitrary three-dimensional micro/nanostructures with a surface roughness acceptable ...
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      Mentions: David D. Sampson University of Western Australia Robert A. McLaughlin

    5. Miniaturized single-fiber-based needle probe for combined imaging and sensing in deep tissue

      Explore OSA | OSA Publishing Probes
      Miniaturized single-fiber-based needle probe for combined imaging and sensing in deep tissue
      The ability to visualize structure while simultaneously measuring chemical or physical properties of a biological tissue has the potential to improve our understanding of complex biological processes. We report the first miniaturized single-fiber-based imaging + sensing imaging+sensing probe capable of simultaneous optical coherence tomography (OCT) imaging and temperature sensing. An OCT lens is fabricated at the distal end of a double-clad fiber, including a thin layer of rare-earth-doped tellurite glass ...
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      Mentions: Robert A. McLaughlin Rodney W. Kirk Jiawen Li

    6. Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration

      Explore SPIE Digital Library Pulmonology
      Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration
      Transbronchial needle aspiration (TBNA) of small lesions or lymph nodes in the lung may result in nondiagnostic tissue samples. We demonstrate the integration of an optical coherence tomography (OCT) probe into a 19-gauge flexible needle for lung tissue aspiration. This probe allows simultaneous visualization and aspiration of the tissue. By eliminating the need for insertion and withdrawal of a separate imaging probe, this integrated design minimizes the risk of dislodging ...
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      Mentions: David D. Sampson University of Western Australia Robert A. McLaughlin

    7. Integrated intravascular ultrasound and optical coherence tomography technology: a promising tool to identify vulnerable plaques

      Explore Журналы СГАУ Cardiology
      Integrated intravascular ultrasound and optical coherence tomography technology: a promising tool to identify vulnerable plaques
      Heart attack is mainly caused by the rupture of a vulnerable plaque. IVUS-OCT is a novel medical imaging modality that provides opportunities for accurate assessment of vulnerable plaquesin vivoin patients. IVUS provides deep penetration to image the whole necrotic core while OCT enables accurate measurement of the fibrous cap of a plaque owing to its high resolution. In this paper, the authors describe the fundamentals, the technical designs and the ...
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      Mentions: Zhongping Chen UC Irvine Jiawen Li

    8. Ultrafast optical-ultrasonic system and miniaturized catheter for imaging and characterizing atherosclerotic plaques in vivo

      Explore Nature Publishing Group Cardiology
      Ultrafast optical-ultrasonic system and miniaturized catheter for imaging and characterizing atherosclerotic plaques in vivo
      Atherosclerotic coronary artery disease (CAD) is the number one cause of death worldwide. The majority of CAD-induced deaths are due to the rupture of vulnerable plaques. Accurate assessment of plaques is crucial to optimize treatment and prevent death in patients with CAD. Current diagnostic techniques are often limited by either spatial resolution or penetration depth. Several studies have proved that the combined use of optical and ultrasonic imaging techniques increase ...
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      Mentions: Zhongping Chen University of Southern California UC Irvine

    10. Trimodality imaging system and intravascular endoscopic probe: combined optical coherence tomography, fluorescence imaging and ultrasound imaging

      Explore opticsinfobase.org Cardiology , Probes
      Trimodality imaging system and intravascular endoscopic probe: combined optical coherence tomography, fluorescence imaging and ultrasound imaging
      ... contrast simultaneously. © 2014 Optical Society of America Shanshan Liang, Teng Ma, Joseph Jing, Xiang Li, Jiawen Li, K. Kirk Shung, Qifa Zhou, Jun Zhang, and Zhongping Chen, "Trimodality imaging system and intravascu...
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      Mentions: Zhongping Chen University of Southern California Jun Zhang

    12. Integrated IVUS-OCT for Real-Time Imaging of Coronary Atherosclerosis

      Explore imaging.onlinejacc.org Cardiology
      Integrated IVUS-OCT for Real-Time Imaging of Coronary Atherosclerosis
      Accurate assessment of atherosclerotic plaque characteristics and the subsequent tailoring of optimal therapy holds great promise for preventing acute coronary syndromes (ACS) and life-threatening sequelae 1 . Combined use of optical coherence tomography (OCT) and intravascular ultrasound (IVUS) was proposed as a potential method for accurate assessment of plaque characteristics and vulnerability ( 2 , ). However, significant challenges remain in trying to adapt an integrated OCT-IVUS system for clinical applications. We report here ...
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      Mentions: Zhongping Chen University of Southern California UC Irvine

    13. Feature Of The Week 11/24/13 : Miniature OCT/IVUS probe for automatically co-registered three-dimensional intracoronary imaging with real-time display

      Explore Optical Coherence Tomography News Cardiology , Probes
      Feature Of The Week 11/24/13 : Miniature OCT/IVUS probe for automatically co-registered three-dimensional intracoronary imaging with real-time display
      ...linical application of this technique in the near future.For more information see recent Article. Courtesy of Jiawen Li and Zhongping Chen from University of California at Irvine.  This work was a collaboration between D...
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      Mentions: Zhongping Chen University of Southern California UC Irvine

    14. Miniature optical coherence tomography-ultrasound probe for automatically coregistered three-dimensional intracoronary imaging with real-time display

      Explore SPIE | Journal Cardiology
      Miniature optical coherence tomography-ultrasound probe for automatically coregistered three-dimensional intracoronary imaging with real-time display
      ...ry segments, were obtained using this probe and our upgraded system. Histology validation is also presented. Jiawen Li ; Teng Ma ; Joseph Jing ; Jun Zhang ; Pranav M. Patel, et al. "Miniature optical coherence tomograp...
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      Mentions: Zhongping Chen University of Southern California UC Irvine

    15. Integrated intravascular optical coherence tomography (OCT) - ultrasound (US) catheter for characterization of atherosclerotic plaques in vivo

      Explore IEEE Xplore Cardiology
      Integrated intravascular optical coherence tomography (OCT) - ultrasound (US) catheter for characterization of atherosclerotic plaques in vivo
      A miniature integrated intravascular optical coherence tomography (OCT) - ultrasound (US) catheter for real-time imaging of atherosclerotic plaques has been developed, providing high resolution and deep tissue penetration at the same time. This catheter, with an outer diameter of 1.18mm, is suitable for imaging in human coronary arteries. The first in vivo 3D imaging of atherosclerotic microstructure in a rabbit abdominal aorta obtained by an integrated OCT-US catheter is presented ...
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      Mentions: Zhongping Chen University of Southern California UC Irvine

    16. Intravascular atherosclerotic imaging with combined fluorescence and optical coherence tomography probe based on a double-clad fiber combiner

      Explore Linking to Scitation Content Cardiology , Probes
      Intravascular atherosclerotic imaging with combined fluorescence and optical coherence tomography probe based on a double-clad fiber combiner
      We developed a multimodality fluorescence and optical coherence tomography probe based on a double-clad fiber (DCF) combiner. The probe is composed of a DCF combiner, grin lens, and micromotor in the distal end. An integrated swept-source optical coherence tomography and fluorescence intensity imaging system was developed based on the combined probe for the early diagnoses of atherosclerosis. This system is capable of real-time data acquisition and processing as well as ...
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      Mentions: Zhongping Chen UC Irvine Jun Zhang
    17. 1-15 of 18 1 2 »
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  4. About Jiawen Li

    Jiawen Li

    Jiawen Li received her BS degree in Optical Engineering from Zhejiang University in 2010, and her PhD degree in Biomedical Engineering from University of California Irvine in 2015. She is currently a Research Fellow at University of Western Australia. She has pioneered in developing and applying the integrated IVUS-OCT technology for clinical practices. During her PhD journey, she published 11 papers in high-impact journals and gave more than 16 talks at prestigious international conferences. In 2015, she won the best poster award at Optics in Cardiology conference. Her research interests include optical coherence tomography, needle probe, multimodality imaging, intravascular imaging, and ultra-thin endoscopes.

  5. Related Topics

    1. Novel combined miniature optical coherence tomography ultrasound probe for in vivo intravascular imaging
      12 articles also mentioned Zhongping Chen
    2. Advances in a fully integrated intravascular OCT-ultrasound system for cardiovascular imaging
      6 articles also mentioned Jun Zhang
    3. Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration
      5 articles also mentioned Robert A. McLaughlin