1. Jeroen Kalkman

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    1. Mentioned In 33 Articles

    2. Optimization-based adaptive optics for optical coherence tomography (Thesis)

      Optimization-based adaptive optics for optical coherence tomography (Thesis)
      Optical coherence tomography (OCT) is a technique for non-invasive imaging based on low coherence interferometry. Its main application is found in ophthalmology, where it is used for 3D in vivo imaging of the cornea and the retina. OCT has evolved over the past decade as one of the most important ancillary tests in ophthalmic practice, providing great diagnostic value for disease screening and monitoring. In retinal OCT imaging, the lateral ...
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    3. The amplitude and the phase or: Measuring directional and random motion with optical coherence tomography (Thesis)

      The amplitude and the phase or: Measuring directional and random motion with optical coherence tomography (Thesis)
      Optical coherence tomography (OCT) uses a low coherence light source and a Michelson interferometer to measure path-length resolved backscatter profiles of samples with micrometer resolution and up to a few millimeters long. The OCT amplitude is typically used to generate images of the sample. Additionally, the amplitude and the phase of the OCT signal can be used to extract quantitative sample information such as layer thickness, refractive index, and flow ...
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    4. Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

      Measurement of biofilm growth and local hydrodynamics using optical coherence tomography
      We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm ...
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    5. Transmission optical coherence tomography based measurement of optical material properties

      Transmission optical coherence tomography based measurement of optical material properties
      We present transmission optical coherence tomography (transmission OCT) as a versatile tool to measure optical material properties of turbid media. The transmission OCT signal is described in detail and it is demonstrated how the group refractive index ( n g ), group velocity dispersion (GVD) and optical attenuation can be determined from this signal. We experimentally validate the refractive index properties of glasses, liquids and glucose water solutions in terms of n ...
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    6. Model-based sensor-less wavefront aberration correction in optical coherence tomography

      Model-based sensor-less wavefront aberration correction in optical coherence tomography
      Several sensor-less wavefront aberration correction methods that correct nonlinear wavefront aberrations by maximizing the optical coherence tomography (OCT) signal are tested on an OCT setup. A conventional coordinate search method is compared to two model-based optimization methods. The first model-based method takes advantage of the well-known optimization algorithm (NEWUOA) and utilizes a quadratic model. The second model-based method (DONE) is new and utilizes a random multidimensional Fourier-basis expansion. The model-based ...
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    7. Simultaneous measurement of localized diffusion and flow using optical coherence tomography

      Simultaneous measurement of localized diffusion and flow using optical coherence tomography
      We report on the simultaneous and localized measurements of the diffusion coefficient and flow velocity based on the normalized autocorrelation function using optical coherence tomography (OCT). Our results on a flowing solution of polystyrene spheres show that the flow velocity and the diffusion coefficient can be reliably estimated in a regime determined by the sample diffusivity, the local flow velocity, and the Gaussian beam waist. We experimentally show that a ...
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    8. Dependent and multiple scattering in transmission and backscattering optical coherence tomography

      Dependent and multiple scattering in transmission and backscattering optical coherence tomography
      We use transmission and backscattering optical coherence tomography (OCT) to distinguish and quantify dependent and multiple scattering effects in turbid media. With transmission OCT the dependent scattering coefficients for a range of monodisperse silica particle suspensions are determined. An excellent agreement is observed between the measured dependent scattering coefficients and calculations based on Mie calculations, the Percus-Yevick radial distribution function, and coherent light scattering theory. Backscattering OCT measurements are fitted ...
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    9. Localized measurement of longitudinal and transverse flow velocities in colloidal suspensions using optical coherence tomography

      Localized measurement of longitudinal and transverse flow velocities in colloidal suspensions using optical coherence tomography
      We report on localized measurement of the longitudinal and transverse flow velocities in a colloidal suspension using optical coherence tomography. We present a model for the path-length resolved autocorrelation function including diffusion and flow, which we experimentally verify. For flow that is not perpendicular to the incident beam, the longitudinal velocity gradient over the coherence gate causes additional decorrelation, which is described by our model. We demonstrate simultaneous imaging of ...
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    10. Integrated-optics-based optical coherence tomography (Thesis)

      Integrated-optics-based optical coherence tomography (Thesis)
      Optical coherence tomography (OCT) is a high resolution, imaging technique that has developed over the last 20 years from a complicated laboratory setup into a ready-to-use commercially available device. Instead of using electronic time gating as being used by ultrasound (US) imaging, in OCT, the optical analogue of US imaging, determines the time of flight using low coherence interferometry. To date, OCT has many clinical applications and is widely used ...
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    11. Common detector for combined raman spectroscopy-optical coherence tomography

      Common detector for combined raman spectroscopy-optical coherence tomography
      An apparatus includes first and second light sources for respectively generating broadband and monochromatic lights, a beamsplitter optically coupled to the first light source for splitting the broadband light into a reference light and a sample light, a reference arm optically coupled to the beamsplitter for receiving the reference light and returning the received reference light into the beamsplitter, a sample arm optically coupled to the beamsplitter and the second ...
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    12. 1-15 of 33 1 2 3 »
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  2. About Jeroen Kalkman

    Jeroen Kalkman

    Jeroen Kalkman (see personal web page ) received his MSc. degree in experimental physics in 1999 from the Vrije Universiteit Amsterdam, The Netherlands. He performed his Ph.D. at the Institute for Atomic and Molecular Physics (AMOLF) in Amsterdam where he worked on Erbium-doped photonic materials. After working for two years at Philips NatLab in Eindhoven, The Netherlands, he moved to the Academic Medical Center in Amsterdam and started working on optical coherence tomography, light tissue interactions, and integrated optics for healthcare applications. In 2013 received a prestigeous Vidi grant, in the same year he started in the Quantitative Imaging group, faculty of Applied Science, TU Delft. His research interests are in adaptive optics, optical coherence tomography, optical tomography, and light tissue interaction.