1. Jeroen Kalkman

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    1. Mentioned In 37 Articles

    2. Quantification of plant morphology and leaf thickness with optical coherence tomography

      Quantification of plant morphology and leaf thickness with optical coherence tomography
      Optical coherence tomography (OCT) can be a valuable imaging tool for in vivo and label-free digital plant phenotyping. However, for imaging leaves, air-filled cavities limit the penetration depth and reduce the image quality. Moreover, up to now quantification of leaf morphology with OCT has been done in one-dimensional or two-dimensional images only, and has often been limited to relative measurements. In this paper, we demonstrate a significant increase in OCT ...
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    3. Multi-scale optical coherence tomography imaging and visualization of Vermeer’s Girl with a Pearl Earring

      Multi-scale optical coherence tomography imaging and visualization of Vermeer’s Girl with a Pearl Earring
      We demonstrate multi-scale multi-parameter optical coherence tomography (OCT) imaging and visualization of Johannes Vermeers painting Girl with a Pearl Earring . Through automated acquisition, OCT image segmentation, and 3D volume stitching we realize OCT imaging at the scale of an entire painting. This makes it possible to image, with micrometer axial and lateral resolution, an entire painting over more than 5 orders of length scale. From the multi-scale OCT data we ...
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    4. Optical coherence computed tomography for quantitative 3D imaging of adult zebrafish

      Optical coherence computed tomography for quantitative 3D imaging of adult zebrafish
      Optical imaging in turbid media like biological tissue is limited by light scattering. We present optical coherence computed tomography (OCCT) as a novel optical imaging modality for ballistic 3D optical imaging of turbid media. In OCCT, coherence and confocal gated measurements from multiple lateral positions and angles are used to reconstruct quantitative 3D images of the optical attenuation and refractive index with tomographic reconstruction algorithms. OCCT allows for high resolution ...
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    5. Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling

      Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling
      In this work the theory of the optical coherence tomography (OCT) signal after sampling, in dispersive media, with noise, and for a turbid medium is presented. The analytical theory is demonstrated with a one-dimensional numerical OCT model for (single) reflectors, dispersive media, and turbid media. For dispersive media the deterioration of the OCT axial resolution is quantified analytically and numerically. The OCT signal to noise ratio (SNR) is analyzed in ...
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    6. Optimization-based adaptive optics for optical coherence tomography (Thesis)

      Optimization-based adaptive optics for optical coherence tomography (Thesis)
      Optical coherence tomography (OCT) is a technique for non-invasive imaging based on low coherence interferometry. Its main application is found in ophthalmology, where it is used for 3D in vivo imaging of the cornea and the retina. OCT has evolved over the past decade as one of the most important ancillary tests in ophthalmic practice, providing great diagnostic value for disease screening and monitoring. In retinal OCT imaging, the lateral ...
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    7. The amplitude and the phase or: Measuring directional and random motion with optical coherence tomography (Thesis)

      The amplitude and the phase or: Measuring directional and random motion with optical coherence tomography (Thesis)
      Optical coherence tomography (OCT) uses a low coherence light source and a Michelson interferometer to measure path-length resolved backscatter profiles of samples with micrometer resolution and up to a few millimeters long. The OCT amplitude is typically used to generate images of the sample. Additionally, the amplitude and the phase of the OCT signal can be used to extract quantitative sample information such as layer thickness, refractive index, and flow ...
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    8. Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

      Measurement of biofilm growth and local hydrodynamics using optical coherence tomography
      We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm ...
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    9. Transmission optical coherence tomography based measurement of optical material properties

      Transmission optical coherence tomography based measurement of optical material properties
      We present transmission optical coherence tomography (transmission OCT) as a versatile tool to measure optical material properties of turbid media. The transmission OCT signal is described in detail and it is demonstrated how the group refractive index ( n g ), group velocity dispersion (GVD) and optical attenuation can be determined from this signal. We experimentally validate the refractive index properties of glasses, liquids and glucose water solutions in terms of n ...
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    10. Model-based sensor-less wavefront aberration correction in optical coherence tomography

      Model-based sensor-less wavefront aberration correction in optical coherence tomography
      Several sensor-less wavefront aberration correction methods that correct nonlinear wavefront aberrations by maximizing the optical coherence tomography (OCT) signal are tested on an OCT setup. A conventional coordinate search method is compared to two model-based optimization methods. The first model-based method takes advantage of the well-known optimization algorithm (NEWUOA) and utilizes a quadratic model. The second model-based method (DONE) is new and utilizes a random multidimensional Fourier-basis expansion. The model-based ...
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    11. Simultaneous measurement of localized diffusion and flow using optical coherence tomography

      Simultaneous measurement of localized diffusion and flow using optical coherence tomography
      We report on the simultaneous and localized measurements of the diffusion coefficient and flow velocity based on the normalized autocorrelation function using optical coherence tomography (OCT). Our results on a flowing solution of polystyrene spheres show that the flow velocity and the diffusion coefficient can be reliably estimated in a regime determined by the sample diffusivity, the local flow velocity, and the Gaussian beam waist. We experimentally show that a ...
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    12. Dependent and multiple scattering in transmission and backscattering optical coherence tomography

      Dependent and multiple scattering in transmission and backscattering optical coherence tomography
      We use transmission and backscattering optical coherence tomography (OCT) to distinguish and quantify dependent and multiple scattering effects in turbid media. With transmission OCT the dependent scattering coefficients for a range of monodisperse silica particle suspensions are determined. An excellent agreement is observed between the measured dependent scattering coefficients and calculations based on Mie calculations, the Percus-Yevick radial distribution function, and coherent light scattering theory. Backscattering OCT measurements are fitted ...
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    13. 1-15 of 37 1 2 3 »
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  2. About Jeroen Kalkman

    Jeroen Kalkman

    Jeroen Kalkman (see personal web page ) received his MSc. degree in experimental physics in 1999 from the Vrije Universiteit Amsterdam, The Netherlands. He performed his Ph.D. at the Institute for Atomic and Molecular Physics (AMOLF) in Amsterdam where he worked on Erbium-doped photonic materials. After working for two years at Philips NatLab in Eindhoven, The Netherlands, he moved to the Academic Medical Center in Amsterdam and started working on optical coherence tomography, light tissue interactions, and integrated optics for healthcare applications. In 2013 received a prestigeous Vidi grant, in the same year he started in the Quantitative Imaging group, faculty of Applied Science, TU Delft. His research interests are in adaptive optics, optical coherence tomography, optical tomography, and light tissue interaction.