1. Jannick P. Rolland

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    1. Mentioned In 75 Articles

    2. Absolute linear-in-k spectrometer designs enabled by freeform optics

      Absolute linear-in-k spectrometer designs enabled by freeform optics
      Linear-in-wavenumber, k , spectrometers have the merits of saving signal processing time and improving the sensitivity of spectral-domain optical coherence tomography (SD-OCT) by avoiding post- k -interpolation. We report on an approach leveraging freeform optics to linearize spectrometers in k to achieve an extremely low residual k -nonlinearity in design. A freeform lens reduced the k -nonlinearity from 2.47% for a benchmark spectrometer to 2.79 10 5 % and 3 ...
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    3. Reverberant 3D optical coherence elastography maps the elasticity of individual corneal layers

      Reverberant 3D optical coherence elastography maps the elasticity of individual corneal layers
      The elasticity mapping of individual layers in the cornea using non-destructive elastography techniques advances diagnosis and monitoring of ocular diseases and treatments in ophthalmology. However, transient Lamb waves, currently used in most dynamic optical coherence and ultrasound elastography techniques, diminish the translation of wave speed into shear/Youngs modulus. Here, we present reverberant 3D optical coherence elastography (Rev3D-OCE), a novel approach leveraging the physical properties of diffuse fields in detecting ...
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    4. Quantitative assessment of human donor corneal endothelium with Gabor domain optical coherence microscopy

      Quantitative assessment of human donor corneal endothelium with Gabor domain optical coherence microscopy
      We report on a pathway for Gabor domain optical coherence microscopy (GD-OCM)-based metrology to assess the donors corneal endothelial layers ex vivo . Six corneas from the Lions Eye Bank at Albany and Rochester were imaged with GD-OCM. The raw 3-D images of the curved corneas were flattened using custom software to enhance the 2-D visualization of endothelial cells (ECs); then the ECs within a circle of 500-m-diameter were analyzed ...
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    5. Capabilities of Gabor-domain optical coherence microscopy for the assessment of corneal disease

      Capabilities of Gabor-domain optical coherence microscopy for the assessment of corneal disease
      To identify the microstructural modification of the corneal layers during the course of the disease, optical technologies have been pushing the boundary of innovation to achieve cellular resolution of deep layers of the cornea. Gabor-domain optical coherence microscopy (GD-OCM), an optical coherence tomography-based technique that can achieve an isotropic of 2-m resolution over a volume of 1mm1mm1.2mm, was developed to investigate the microstructural modifications of corneal layers in four ...
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    6. Telecentric broadband objective lenses for optical coherence tomography (OCT) in the context of low uncertainty metrology of freeform optical components: from design to testing for wavefront and telecentricity

      Telecentric broadband objective lenses for optical coherence tomography (OCT) in the context of low uncertainty metrology of freeform optical components: from design to testing for wavefront and telecentricity
      Freeform optical components enable significant advances for optical systems. A major challenge for freeform optics is the current lack of metrology methods with measurement uncertainty on the order of tens of nanometers or less. Towards addressing this challenge, optical coherence tomography (OCT) is a viable technique. In the context of low uncertainty metrology, the design requirements pertaining to the sample arm of an OCT metrology system are explicitly addressed in ...
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    7. Point-cloud noncontact metrology of freeform optical surfaces

      Point-cloud noncontact metrology of freeform optical surfaces
      Full Article Figures (16) Tables (2) Equations (14) References (52) Cited By (0) Back to Top Get PDF Abstract In this paper, we demonstrate the development of a point-cloud metrology method for the noncontact, high resolution, high precision testing of freeform surfaces. The method leverages swept source optical coherence tomography together with a common-path setup in the sample arm configured to mitigate the axial jitter caused by scanning and environmental ...
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    8. Viscoelastic characterization of dispersive media by inversion of a general wave propagation model in optical coherence elastography

      Viscoelastic characterization of dispersive media by inversion of a general wave propagation model in optical coherence elastography
      Determining the mechanical properties of tissue such as elasticity and viscosity is fundamental for better understanding and assessment of pathological and physiological processes. Dynamic optical coherence elastography uses shear/surface wave propagation to estimate frequency-dependent wave speed and Youngs modulus. However, for dispersive tissues, the displacement pulse is highly damped and distorted during propagation, diminishing the effectiveness of peak tracking approaches. The majority of methods used to determine mechanical properties ...
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    9. Measurement of the lipid and aqueous layers of a tear film

      Measurement of the lipid and aqueous layers of a tear film
      Systems and methods for determining thickness of lipid and aqueous layers of a tear film in which a spectrum array is generated from optical coherence tomography and input into a statistical estimator, which determines the thickness of the lipid and/or aqueous layers at a nanometer resolution based on the inputted spectrum and other information, such as information about a laser intensity noise, Poisson noise, and dark noise associated with ...
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    10. Comparative study of shear wave-based elastography techniques in optical coherence tomography

      Comparative study of shear wave-based elastography techniques in optical coherence tomography
      We compare five optical coherence elastography techniques able to estimate the shear speed of waves generated by one and two sources of excitation. The first two techniques make use of one piezoelectric actuator in order to produce a continuous shear wave propagation or a tone-burst propagation (TBP) of 400 Hz over a gelatin tissue-mimicking phantom. The remaining techniques utilize a second actuator located on the opposite side of the region ...
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    11. 3D wide field-of-view Gabor-domain optical coherence microscopy advancing real-time in-vivo imaging and metrology

      3D wide field-of-view Gabor-domain optical coherence microscopy advancing real-time in-vivo imaging and metrology
      Real-time volumetric high-definition wide-field-of-view in-vivo cellular imaging requires micron-scale resolution in 3D. Compactness of the handheld device and distortion-free images with cellular resolution are also critically required for onsite use in clinical applications. By integrating a custom liquid lens-based microscope and a dual-axis MEMS scanner in a compact handheld probe, Gabor-domain optical coherence microscopy (GD-OCM) breaks the lateral resolution limit of optical coherence tomography through depth, overcoming the tradeoff between ...
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    12. Optical Assessment of Soft Contact Lens Edge-Thickness

      Optical Assessment of Soft Contact Lens Edge-Thickness
      Purpose: To assess the edge shape of soft contact lenses using Gabor-Domain Optical Coherence Microscopy (GD-OCM) with a 2-m imaging resolution in three dimensions and to generate edge-thickness profiles at different distances from the edge tip of soft contact lenses. Methods: A high-speed custom-designed GD-OCM system was used to produce 3D images of the edge of an experimental soft contact lens (Bausch + Lomb, Rochester, NY) in four different configurations: in ...
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    13. Volumetric rendering and metrology of spherical gradient refractive index lens imaged by angular scan optical coherence tomography system

      Volumetric rendering and metrology of spherical gradient refractive index lens imaged by angular scan optical coherence tomography system
      In this paper, we develop the methodology, including the refraction correction, geometrical thickness correction, coordinate transformation, and layer segmentation algorithms, for 3D rendering and metrology of a layered spherical gradient refractive index (S-GRIN) lens based on the imaging data collected by an angular scan optical coherence tomography (OCT) system. The 3D mapping and rendering enables direct 3D visualization and internal defect inspection of the lens. The metrology provides assessment of ...
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    14. MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy

      MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy
      High-speed scanning in optical coherence tomography (OCT) often comes with either compromises in image quality, the requirement for post-processing of the acquired images, or both. We report on distortion-free OCT volumetric imaging with a dual-axis micro-electro-mechanical system (MEMS)-based handheld imaging probe. In the context of an imaging probe with optics located between the 2D MEMS and the sample, we report in this paper on how pre-shaped open-loop input signals ...
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  2. About Jannick P. Rolland

    Jannick P. Rolland

    Jannick Rolland is the Brian J. Thompson Professor of Optical Engineering and Associate Director of the R.E. Hopkins Center for Optical Design & Engineering, and Professor of Biomedical Engineering at the University of Rochester.  Dr. Rolland also runs the Optical Diagnostics and Applications Laboratory (ODALab).

  3. Quotes

    1. We leveraged emerging technology that is coming out of cell phones, like liquid lenses, and developed a new way to record the data using a spectrometer and dynamic focusing...A liquid lens is made of water and oil on an electrode. When voltage is applied, the surface of the electrode becomes less hydrophobic...By changing the voltage, you can make things more or less hydrophobic and have the water being repulsed or attracted toward the electrode...The oil-water interface changes and you create bending, the different curvature at the interface" which serves as the lens. Changing the voltage changes the focus.
      In Breakthrough 3-D optical imaging possible in vivo
    2. My hope is that, in the future, this technology could remove significant inconvenience and expense from the process of skin lesion diagnosis...When a patient walks into a clinic with a suspicious mole, for instance, they wouldn't have to have it necessarily surgically cut out of their skin or be forced to have a costly and time-consuming MRI done. Instead, a relatively small, portable device could take an image that will assist in the classification of the lesion right in the doctor's office."
      In A New High-Resolution Method for Imaging Below the Skin using a Liquid Lens