1. Jannick P. Rolland

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    1. Mentioned In 82 Articles

    2. Speckle Statistics of Biological Tissues in Optical Coherence Tomography

      Speckle Statistics of Biological Tissues in Optical Coherence Tomography
      The speckle statistics of optical coherence tomography images of biological tissue have been studied using several historical probability density functions. A recent hypothesis implies that underlying power-law distributions in the medium structure, such as the fractal branching vasculature, will contribute to power-law probability distributions of speckle statistics. Specifically, these are the Burr type XII distribution for speckle amplitude, the Lomax distribution for intensity, and the generalized logistic distribution for log ...
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    3. Cascade optical coherence tomography (C-OCT)

      Cascade optical coherence tomography (C-OCT)
      Significant advances for optical systems in terms of both performance and packaging are enabled by freeform optical components. Yet, surface form metrology for freeform optics remains a challenge. We developed and investigated a point-cloud cascade optical coherence tomography (C-OCT) technique to address this metrology challenge. The mathematical framework for the working principle of C-OCT is presented. A novel detection scheme is developed to enable high-speed measurements. Experimental results validate the ...
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    4. LighTopTech Corp. Receives Small Business Innovation Research Phase II Award from the US National Institutes of Health (NIH)

      LighTopTech Corp. Receives Small Business Innovation Research Phase II Award from the US National Institutes of Health (NIH)
      LighTopTech Corp., an upstate New York-based company building innovative optical instruments to bring to market disruptive imaging technologies industrial and medical fields, has been awarded a Phase II Small Business Innovation Research (SBIR) award by the National Eye Institute of the National Institutes of Health (NIH). The NIH Phase II award will allow LighTopTech to develop the first 3D high-definition imaging instrument based on Gabor-Domain Optical Coherence Microscopy (GDOCM) for ...
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    5. In vivo imaging of corneal nerves and cellular structures in mice with Gabor-domain optical coherence microscopy

      In vivo imaging of corneal nerves and cellular structures in mice with Gabor-domain optical coherence microscopy
      Gabor-domain optical coherence microscopy (GDOCM) demonstrated in vivo corneal imaging with cellular resolution and differentiation in mice over a field of view of 1 mm 2 . Contact and non-contact imaging was conducted on six healthy and six hyperglycemic C57BL/6J mice. Cellular resolution in the 3D GDOCM images was achieved after motion correction. Corneal nerve fibers were traced and their lengths and branches calculated. Noncontact, label-free imaging of corneal nerves ...
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    6. Imaging Techniques for the Visualization and Evaluation of Tear Film Dynamics (Book Chapter)

      Imaging Techniques for the Visualization and Evaluation of Tear Film Dynamics (Book Chapter)
      Significant efforts have been made with the development of various imaging techniques to visualize and understand the tear film dynamics. This chapter reviews three imaging techniques with established impact on imaging the tear film dynamics: fluorescent imaging, interferometry, and optical coherence tomography.
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    7. Absolute linear-in-k spectrometer designs enabled by freeform optics

      Absolute linear-in-k spectrometer designs enabled by freeform optics
      Linear-in-wavenumber, k , spectrometers have the merits of saving signal processing time and improving the sensitivity of spectral-domain optical coherence tomography (SD-OCT) by avoiding post- k -interpolation. We report on an approach leveraging freeform optics to linearize spectrometers in k to achieve an extremely low residual k -nonlinearity in design. A freeform lens reduced the k -nonlinearity from 2.47% for a benchmark spectrometer to 2.79 10 5 % and 3 ...
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    8. Reverberant 3D optical coherence elastography maps the elasticity of individual corneal layers

      Reverberant 3D optical coherence elastography maps the elasticity of individual corneal layers
      The elasticity mapping of individual layers in the cornea using non-destructive elastography techniques advances diagnosis and monitoring of ocular diseases and treatments in ophthalmology. However, transient Lamb waves, currently used in most dynamic optical coherence and ultrasound elastography techniques, diminish the translation of wave speed into shear/Youngs modulus. Here, we present reverberant 3D optical coherence elastography (Rev3D-OCE), a novel approach leveraging the physical properties of diffuse fields in detecting ...
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    9. Quantitative assessment of human donor corneal endothelium with Gabor domain optical coherence microscopy

      Quantitative assessment of human donor corneal endothelium with Gabor domain optical coherence microscopy
      We report on a pathway for Gabor domain optical coherence microscopy (GD-OCM)-based metrology to assess the donors corneal endothelial layers ex vivo . Six corneas from the Lions Eye Bank at Albany and Rochester were imaged with GD-OCM. The raw 3-D images of the curved corneas were flattened using custom software to enhance the 2-D visualization of endothelial cells (ECs); then the ECs within a circle of 500-m-diameter were analyzed ...
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    10. Capabilities of Gabor-domain optical coherence microscopy for the assessment of corneal disease

      Capabilities of Gabor-domain optical coherence microscopy for the assessment of corneal disease
      To identify the microstructural modification of the corneal layers during the course of the disease, optical technologies have been pushing the boundary of innovation to achieve cellular resolution of deep layers of the cornea. Gabor-domain optical coherence microscopy (GD-OCM), an optical coherence tomography-based technique that can achieve an isotropic of 2-m resolution over a volume of 1mm1mm1.2mm, was developed to investigate the microstructural modifications of corneal layers in four ...
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    11. Telecentric broadband objective lenses for optical coherence tomography (OCT) in the context of low uncertainty metrology of freeform optical components: from design to testing for wavefront and telecentricity

      Telecentric broadband objective lenses for optical coherence tomography (OCT) in the context of low uncertainty metrology of freeform optical components: from design to testing for wavefront and telecentricity
      Freeform optical components enable significant advances for optical systems. A major challenge for freeform optics is the current lack of metrology methods with measurement uncertainty on the order of tens of nanometers or less. Towards addressing this challenge, optical coherence tomography (OCT) is a viable technique. In the context of low uncertainty metrology, the design requirements pertaining to the sample arm of an OCT metrology system are explicitly addressed in ...
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    12. Point-cloud noncontact metrology of freeform optical surfaces

      Point-cloud noncontact metrology of freeform optical surfaces
      Full Article Figures (16) Tables (2) Equations (14) References (52) Cited By (0) Back to Top Get PDF Abstract In this paper, we demonstrate the development of a point-cloud metrology method for the noncontact, high resolution, high precision testing of freeform surfaces. The method leverages swept source optical coherence tomography together with a common-path setup in the sample arm configured to mitigate the axial jitter caused by scanning and environmental ...
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    13. 1-15 of 82 1 2 3 4 5 6 »
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  2. About Jannick P. Rolland

    Jannick P. Rolland

    Jannick Rolland is the Brian J. Thompson Professor of Optical Engineering and Associate Director of the R.E. Hopkins Center for Optical Design & Engineering, and Professor of Biomedical Engineering at the University of Rochester.  Dr. Rolland also runs the Optical Diagnostics and Applications Laboratory (ODALab).

  3. Quotes

    1. We leveraged emerging technology that is coming out of cell phones, like liquid lenses, and developed a new way to record the data using a spectrometer and dynamic focusing...A liquid lens is made of water and oil on an electrode. When voltage is applied, the surface of the electrode becomes less hydrophobic...By changing the voltage, you can make things more or less hydrophobic and have the water being repulsed or attracted toward the electrode...The oil-water interface changes and you create bending, the different curvature at the interface" which serves as the lens. Changing the voltage changes the focus.
      In Breakthrough 3-D optical imaging possible in vivo
    2. My hope is that, in the future, this technology could remove significant inconvenience and expense from the process of skin lesion diagnosis...When a patient walks into a clinic with a suspicious mole, for instance, they wouldn't have to have it necessarily surgically cut out of their skin or be forced to have a costly and time-consuming MRI done. Instead, a relatively small, portable device could take an image that will assist in the classification of the lesion right in the doctor's office."
      In A New High-Resolution Method for Imaging Below the Skin using a Liquid Lens