1. James Y. Jiang

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    1. Mentioned In 39 Articles

    2. Microscopy system with auto-focus adjustment by low-coherence interferometry

      Microscopy system with auto-focus adjustment by low-coherence interferometry
      Disclosed are several technical approaches of using low coherence interferometry techniques to create an autofocus apparatus for optical microscopy. These approaches allow automatic focusing on thin structures that are positioned closely to reflective surfaces and behind refractive material like a cover slip, and automated adjustment of focus position into the sample region without disturbance from reflection off adjacent surfaces. The measurement offset induced by refraction of material that covers the ...
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    3. Apparatus and methods for one or more wavelength swept lasers and the detection of signals thereof

      Apparatus and methods for one or more wavelength swept lasers and the detection of signals thereof
      An optical instrument including at least a first and second wavelength swept vertical cavity laser (VCL) sources. The wavelength sweeping ranges spanned by the first and second VCL sources may differ with a region of spectral overlap. The first and second VCL sources may be operable under different modes of operation, wherein the modes of operation differ in at least one of: sweep repetition rate, sweep wavelength range, sweep center ...
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    4. Agile Imaging System

      Agile Imaging System
      An agile optical imaging system for optical coherence tomography imaging using a tunable source comprising a wavelength tunable VCL laser is disclosed. The tunable source has long coherence length and is capable of high sweep repetition rate, as well as changing the sweep trajectory, sweep speed, sweep repetition rate, sweep linearity, and emission wavelength range on the fly to support multiple modes of OCT imaging. The imaging system also offers ...
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    5. Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology

      Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology
      ...»View Author Affiliations Tsung-Han Tsai,^1 Benjamin Potsaid,^1,^2 Yuankai K. Tao,^1 Vijaysekhar Jayaraman,^3 James Jiang,^2 Peter J. S. Heim,^4 Martin F. Kraus,^1,^5 Chao Zhou,^1 Joachim Hornegger,^5 Hiroshi Mashimo,^6 ...
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    6. High-speed ultra-broad tuning MEMS-VCSELs for imaging and spectroscopy

      High-speed ultra-broad tuning MEMS-VCSELs for imaging and spectroscopy
      In the last 2 years, the field of micro-electro-mechanical systems tunable vertical cavity surface-emitting lasers (MEMS-VCSELs) has seen dramatic improvements in laser tuning range and tuning speed, along with expansion into unexplored wavelength bands, enabling new applications. This paper describes the design and performance of high-speed ultra-broad tuning range 1050nm and 1310nm MEMS-VCSELs for medical imaging and spectroscopy. Key results include achievement of the first MEMS-VCSELs at 1050nm and 1310nm ...
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    7. High-precision, high-accuracy ultralong-range swept-source optical coherence tomography using vertical cavity surface emitting laser light source

      High-precision, high-accuracy ultralong-range swept-source optical coherence tomography using vertical cavity surface emitting laser light source
      ...013 Optical Society of America Ireneusz Grulkowski, Jonathan J. Liu, Benjamin Potsaid, Vijaysekhar Jayaraman, James Jiang, James G. Fujimoto, and Alex E. Cable, "High-precision, high-accuracy ultralong-range swept-source...
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    8. Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers

      Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers
      We demonstrate swept source OCT utilizing vertical-cavity surface emitting laser (VCSEL) technology for in vivo high speed retinal, anterior segment and full eye imaging. The MEMS tunable VCSEL enables long coherence length, adjustable spectral sweep range and adjustable high sweeping rate (50–580 kHz axial scan rate). These features enable integration of multiple ophthalmic applications into one instrument. The operating modes of the device include: ultrahigh speed, high resolution retinal ...
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    9. Dynamic light scattering optical coherence tomography

      Dynamic light scattering optical coherence tomography
      We introduce an integration of dynamic light scattering (DLS) and optical coherence tomography (OCT) for high-resolution 3D imaging of heterogeneous diffusion and flow. DLS analyzes fluctuations in light scattered by particles to measure diffusion or flow of the particles, and OCT uses coherence gating to collect light only scattered from a small volume for high-resolution structural imaging. Therefore, the integration of DLS and OCT enables high-resolution 3D imaging of diffusion ...
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    10. 1065nm and 1310nm MEMS tunable VCSEL light source technology for OCT imaging

      1065nm and 1310nm MEMS tunable VCSEL light source technology for OCT imaging
      A novel vertical-cavity surface-emitting laser with a microelectromechanical tuning element enables high-speed, centimeter-range optical coherence tomography. Optical coherence tomography (OCT) is a noninvasive optical imaging technique that can generate micron-resolution 2D and 3D images of tissue and other scattering materials.1 First demonstrated for imaging the human eye and coronary arteries in 1991,1 OCT has become a clinical standard for diagnosing and monitoring treatment of eye disease, with approximately ...
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    11. Design and performance of broadly tunable, narrow line-width, high repetition rate 1310nm VCSELs for swept source optical coherence tomography

      Design and performance of broadly tunable, narrow line-width, high repetition rate 1310nm VCSELs for swept source optical coherence tomography
      MEMS tunable vertical cavity surface emitting laser (MEMS-VCSEL) development, over the past two decades, has primarily focused on communications and spectroscopic applications. Because of the narrow line-width, single-mode operation, monolithic fabrication, and high-speed capability of these devices, MEMS-VCSELs also present an attractive optical source for emerging swept source optical coherence tomography (SSOCT) systems. In this paper, we describe the design and performance of broadly tunable MEMS-VCSELs targeted for SSOCT, emphasizing ...
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    12. MEMS tunable VCSEL light source for ultrahigh speed 60kHz - 1MHz axial scan rate and long range centimeter class OCT imaging

      MEMS tunable VCSEL light source for ultrahigh speed 60kHz - 1MHz axial scan rate and long range centimeter class OCT imaging
      This paper demonstrates new wavelength swept light source technology, MEMS tunable VCSELs, for OCT imaging. The VCSEL achieves a combination of ultrahigh sweep speeds, wide spectral tuning range, flexibility in sweep trajectory, and extremely long coherence length, which cannot be simultaneously achieved with other technologies. A second generation prototype VCSEL is optically pumped at 980nm and a low mass electrostatically tunable mirror enables high speed wavelength tuning centered at ~1310nm ...
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    13. In vivo, label-free, three-dimensional quantitative imaging of kidney microcirculation using Doppler optical coherence tomography

      In vivo, label-free, three-dimensional quantitative imaging of kidney microcirculation using Doppler optical coherence tomography
      Doppler optical coherence tomography (DOCT) is a functional extension of optical coherence tomography (OCT) and is currently being employed in several clinical arenas to quantify blood flow in vivo. In this study, the objective was to investigate the feasibility of DOCT to image kidney microcirculation, specifically, glomerular blood flow. DOCT is able to capture three-dimensional (3D) data sets consisting of a series of cross-sectional images in real time, which enables ...
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    14. 1-15 of 39 1 2 3 »
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  2. About James Y. Jiang

    James Y. Jiang

    James Yi Jiang received the B.S. degrees in applied physics and in computer science in 1997 and the Ph. D. degree in optics in 2002 from Shanghai Jiao Tong University. He joined Beckman Laser Institute, University of California, Irvine as a post-doc researcher in 2003, where he focused on second harmonic OCT and high-resolution OCT research projects. He authored a number of scientific publications and was awarded outstanding poster presentation award in 2004 Gorden Research Conference of Lasers in Medicine & Biology. In 2005, he joined Thorlabs Inc. as a researcher until now focusing on the research and development of novel laser imaging systems for biomedical and industrial applications.