1. James G. Fujimoto

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    1. Mentioned In 391 Articles

    2. Optical Coherence Tomography Imaging in Developmental Biology

      Optical Coherence Tomography Imaging in Developmental Biology
      Optical coherence tomography (OCT) is an attractive imaging technique for developmental biology because it permits the imaging of tissue microstructure in situ, yielding micron-scale image resolution without the need for excision of a specimen and tissue processing. OCT enables repeated imaging studies to be performed on the same specimen in order to track developmental changes. OCT is analogous to ultrasound B mode imaging except that it uses low-coherence light rather ...
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    3. Comparison of Optic Disc Margin Identified by Color Disc Photography and High-Speed Ultrahigh-Resolution Optical Coherence Tomography

      ...; Larry Kagemann, MSc; Michelle L. Gabriele, BSc; Kyung Rim Sung, MD; Tarkan Mumcuoglu, MD; Jay S. Duker, MD; James G. Fujimoto, PhD; Joel S. Schuman, MD Arch Ophthalmol. 2008;126(1):58-64. Objective  To determine the co...
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    4. State-of-the-art retinal optical coherence tomography.

      OCT functions as a type of optical biopsy, providing information on retinal pathology in situ and in real time, with resolutions approaching that of excisional biopsy and histopathology. The development of ultrabroad-bandwidth and tunable light sources, as well as high-speed Fourier detection techniques, has enabled a significant improvement in ophthalmic optical coherence tomography (OCT) imaging performance. Three-dimensional, ultrahigh-resolution OCT (UHR OCT) can provide information on intraretinal morphology that is not ...
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    5. Photonic device fabrication in glass by use of nonlinear materials processing with a femtosecond laser oscillator.

      Single-mode X couplers and three-dimensional waveguides are fabricated in transparent glasses by use of an unamplified femtosecond laser generating energies of up to 100 nJ. Changing fabrication parameters such as power and scanning speed permits creation of waveguides with a wide range of structures and refractive-index difference. Optical coherence tomography shows large refractive-index changes of up to ~10(-2) in the waveguides; these changes are consistent with guided mode analysis ...
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    6. In vivo ultrahigh-resolution optical coherence tomography.

      Ultrahigh-resolution optical coherence tomography (OCT) by use of state of the art broad-bandwidth femtosecond laser technology is demonstrated and applied to in vivo subcellular imaging. Imaging is performed with a Kerr-lens mode-locked Ti:sapphire laser with double-chirped mirrors that emits sub-two-cycle pulses with bandwidths of up to 350 nm, centered at 800 nm. Longitudinal resolutions of ~1mum and transverse resolution of 3mum, with a 110-dB dynamic range, are achieved in ...
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    7. Comparison of three-dimensional optical coherence tomography and high resolution photography for art conservation studies

      ...H. Lie, T. Hensick, R. Spronk, S. Wolohojian, N. Khandekar, J. Y. Jiang, S. Barry, A. E. Cable, R. Huber, and J. G. Fujimoto, "Comparison of three-dimensional opticalcoherence tomography and high resolution photography f...
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    8. Photoreceptor Disruption Secondary to Posterior Vitreous Detachment as Visualized Using High-Speed Ultrahigh-Resolution Optical Coherence Tomography

      ...Coherence Tomography Andre J. Witkin, MD; Maciej Wojtkowski, PhD; Elias Reichel, MD; Vivek J. Srinivasan, MS; James G. Fujimoto, PhD; Joel S. Schuman, MD; Jay S. Duker, MD Arch Ophthalmol. 2007;125(11):1579-1580. Optical...
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    9. High-resolution imaging of progressive articular cartilage degeneration

      High-resolution imaging of progressive articular cartilage degeneration
      The objective of this study was to develop and verify a new technique for monitoring the progression of osteoarthritis (OA) by combining a rat model with the imaging modality optical coherence tomography (OCT). Time-sequential, in vivo, OCT imaging was performed on the left femoral condyles of 12 Wistar rats following sodium-iodoacetic acid-induced OA progression. The right femoral condyles (untreated) were also imaged and served as controls. Imaging was performed on ...
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    10. 346-360 of 391 « 1 2 ... 21 22 23 24 25 26 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About James G. Fujimoto

    James G. Fujimoto

    James Fujimoto is Elihu Thomson Professor of Electrical Engineering and Computer Science at the Massachusetts Institute of Technology, visiting professor of ophthalmology at Tufts University School of Medicine, and adjunct professor at the Medical University of Vienna. His group and collaborators invented and developed OCT, and he co-founded Advanced Ophthalmic Devices and LightLab Imaging, which developed cardiovascular OCT. He has published over 450 peer-reviewed articles and co-edited 13 books. He is a director of the International Society for Optics and Photonics (SPIE) and general co-chair of the SPIE BIOS symposium, and previously was co-chair of two Conferences on Lasers and Electro Optics and the European Conference on Biomedical Optics, and director of the Optical Society (OSA). He has received the Zeiss Research Award, IEEE Photonics Award, and OSA Ives Medal, and he shared the 2002 Rank Prize in Optoelectronics and 2012 António Champalimaud Vision Prize. He is a member of the National Academy of Engineering, National Academy of Sciences, and American Academy of Arts and Sciences.

  3. Quotes

    1. The development of OCT in the early 1990s greatly benefited from components and methods used in fiber-optical communications...And still, 25 years later, advances in the optical communications industry continue to greatly benefit OCT.
      In Macro-scale OCT heralds new industrial uses for the technique
    2. Our study demonstrates world-record results in cubic meter volume imaging, with at least an order of magnitude larger depth range and volume compared to previous demonstrations of three-dimensional OCT...These results provide a proof-of-principle demonstration for using OCT in this new regime...Long-range OCT is a new range of operation that requires extremely high performance light sources, integrated optical receivers and signal processing.
      In Researchers achieve meter-scale optical coherence tomography for first time
    3. "The development of OCT in the early 1990s greatly benefited from components and methods used in fiber optical communications,. And still, 25 years later, advances in the optical communications industry continue to greatly benefit OCT.
      In Researchers achieve meter-scale optical coherence tomography for first time
    4. The newest swept-source OCT has the advantage that the light source frequency sweep range and repetition rate can be adjusted to tailor the resolution, imaging range, and axial scan repetition rate for the specific imaging application.
      In Swept-source OCT and glaucoma
    5. We are now approaching a point with OCT where ophthalmologists have a view of the retina that is similar to that of pathologists...In the future, functional imaging will make subtle changes in pathology more measurable, and these advances will enhance sensitivity when monitoring disease progression and response to therapy.
      In How hardware, software advances expand OCT capabilities
    6. Hand-held instruments can enable screening a wider population outside the traditional points of care...The hand-held platform allows the diagnosis or screening to be performed in a much wider range of settings...Developing screening methods that are accessible to the larger population could significantly reduce unnecessary vision loss.
      In Early Detection of Blinding Eye Disease Could be as Easy as Scanning a Barcode
    7. Hand-held instruments can enable screening a wider population outside the traditional points of care.
      In Early Detection of Blinding Eye Disease Could be as Easy as Scanning a Barcode
    8. The hand-held platform allows the diagnosis or screening to be performed in a much wider range of settings.
      In Early Detection of Blinding Eye Disease Could be as Easy as Scanning a Barcode
    9. Partnership between academics and industry was critical for the development of OCT and is a powerful approach for translating new scientific discoveries into real world clinical practice...Clinical researchers on our team as well as other clinicians at leading international medical centers worked with the early OCT technology, exploring new clinical applications and blazing a trail that the broader clinical community could follow. This interdisciplinary approach was key to the success of this technology.
      In MIT Researchers Dr. James Fujimoto and Mr. Eric Swanson Awarded the 2012 António Champalimaud Vision Award
    10. OCT has the advantage that it can image 1 or 2 millimeters below the surface with high resolution, noninvasively...Increased imaging speed is important; it allows broader coverage or improved resolution...the concept is not that the technology is trying to diagnose the cancer per se, since excisional biopsies do that well...Instead, it is coupling 3D OCT scanning across the sampling area with standard biopsies.
      In Optical Tomography May Aid 3D Cancer Diagnostics