1. James G. Fujimoto

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    1. Mentioned In 272 Articles

    2. Feature Of The Week 4/2/14: A Compact High-Performance Hand-Held Device for Extending Ophthalmic OCT to New Points of Care (Narrated Presentation)

      Feature Of The Week 4/2/14: A Compact High-Performance Hand-Held Device for Extending Ophthalmic OCT to New Points of Care (Narrated Presentation)
      ...primary care, developing countries, and military medicine. For more information see recent Article . Courtesy James Fujimoto from the Massachusetts Institute of Technology We developed an ultrahigh speed, handheld swept ...
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    3. Quantitative Optical Coherence Tomography Angiography of Choroidal Neovascularization in Age-related Macular Degeneration

      Quantitative Optical Coherence Tomography Angiography of Choroidal Neovascularization in Age-related Macular Degeneration
      ...gnition Lab and School of Advanced Optical Technologies, University Erlangen-Nuremberg, Erlangen, Germany , * James G. Fujimoto, PhD Affiliations + Department of Electrical Engineering & Computer Science, Massachusetts I...
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    4. Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light source and micromotor catheter

      Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light source and micromotor catheter
      ...man ; Martin F. Kraus ; Joachim Hornegger ; Marisa Figueiredo ; Qin Huang ; Hiroshi Mashimo ; Alex E. Cable ; James G. Fujimoto; Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light so...
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    5. En Face OCT Imaging of the Eye - Special Interest Group for the 2014 ARVO Annual Meeting May 2014

      En Face OCT Imaging of the Eye - Special Interest Group  for the 2014 ARVO Annual Meeting May 2014
      ... – SIG, Session Number: 355.  The Organizer is Andre Romano and includes the following speakers: David Huang, James Fujimoto, Philip Rosenfeld. Bruno Lumbroso, Gabriel Coscas, Min Wang, Richard Rosen. More can be found b...
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    6. Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath

      Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath

      We characterized en face features of the retinal pigment epithelium (RPE) and choroid in eyes with chronic central serous chorioretinopathy (CSCR) using a high-speed, enhanced tissue penetration, swept-source optical coherence tomography (SS-OCT) prototype. Fifteen eyes of 13 consecutive patients with the clinical diagnosis of CSCR were prospectively examined with SS-OCT. Three-dimensional 6x6mm macular cube raster scans were obtained with SS-OCT operating at 1050nm wavelength and 100,000 A-lines/sec with 6µm axial resolution. Segmentation of the RPE generated a reference surface; en face SS-OCT images of the RPE and choroid were extracted at varying depths every 3.5 µm ...

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    7. Analysis of short-term change in subfoveal choroidal thickness in eyes with age-related macular degeneration using optical coherence tomography

      Analysis of short-term change in subfoveal choroidal thickness in eyes with age-related macular degeneration using optical coherence tomography

      BACKGROUND AND OBJECTIVE: To measure the subfoveal choroidal thickness in patients with age-related macular degeneration (AMD) over 6 months. PATIENTS AND METHODS: A retrospective, observational study of patients with AMD followed up for 6 months at the New England Eye Center. Baseline and 6-month follow-up subfoveal choroidal thickness was measured using spectral-domain OCT and compared. RESULTS: For the entire cohort, there was statistically significant thinning of the subfoveal choroidal thickness at 6 months compared to baseline that was driven by the cohort of patients with neovascular AMD (181.2 ± 75 μm to 173.4 ± 63 μm; P = .049). CONCLUSION: There ...

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    8. State of the Industry report on Optical Coherence Tomography

      State of the Industry report on Optical Coherence Tomography

      The first commercial optical coherence tomography (OCT) imagers were introduced to ophthalmology by Advanced Ophthalmic Devices (now owned by Zeiss Meditec) in 1992. Since then, the market for OCT systems has grown at an impressive compounded annual rate of about 45%. This segment of the biophotonics marketplace has flourished because OCT enables sub-surface imaging of translucent or opaque materials, such as human tissue, in real time at micron resolution and without the use of ionizing radiation. As a result, last year’s global sales of all OCT systems exceeded $400 million and the market now supports more than 36 OCT ...

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      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
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    3. Technology:

      Broadband Sources, Probes, Tunable Sources, Velocimetry
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      Jobs & Studentships, Student Theses, Textbooks
  2. About James G. Fujimoto

    James G. Fujimoto

    James. G. Fujimoto is a principal investigator in the Research Laboratory of Electronics (RLE) at the Massachusetts Institute of Technology (MIT). He received his S.B., S.M., and Ph.D. in electrical engineering from MIT in 1979, 1981, and 1984 respectively. He joined the MIT faculty in 1985 as Assistant Professor of Electrical Engineering. Since 1994, he has been Professor of Electrical Engineering at MIT and Adjunct Professor of Ophthalmology at Tufts University.

    Professor Fujimoto's area of research involves the development and application of femtosecond laser technology, studies of ultrafast phenomena, and laser medicine and surgery. His research group in RLE and collaborators invented optical coherence tomography and pioneered its development. 

    James G Fujimoto has published over 250 journal articles, is editor or author of 5 books, and holds numerous U.S. patents for his discoveries. He is a fellow of the National Academy of Engineering and the American Association for the Advancement of Science. Among his many honors include the 1999 Discover Magazine Award for Technological Innovation and the 2001 Rank Prize in Optoelectronics.

  3. Quotes

    1. We are now approaching a point with OCT where ophthalmologists have a view of the retina that is similar to that of pathologists...In the future, functional imaging will make subtle changes in pathology more measurable, and these advances will enhance sensitivity when monitoring disease progression and response to therapy.
      In How hardware, software advances expand OCT capabilities
    2. Hand-held instruments can enable screening a wider population outside the traditional points of care...The hand-held platform allows the diagnosis or screening to be performed in a much wider range of settings...Developing screening methods that are accessible to the larger population could significantly reduce unnecessary vision loss.
      In Early Detection of Blinding Eye Disease Could be as Easy as Scanning a Barcode
    3. Hand-held instruments can enable screening a wider population outside the traditional points of care.
      In Early Detection of Blinding Eye Disease Could be as Easy as Scanning a Barcode
    4. The hand-held platform allows the diagnosis or screening to be performed in a much wider range of settings.
      In Early Detection of Blinding Eye Disease Could be as Easy as Scanning a Barcode
    5. Partnership between academics and industry was critical for the development of OCT and is a powerful approach for translating new scientific discoveries into real world clinical practice...Clinical researchers on our team as well as other clinicians at leading international medical centers worked with the early OCT technology, exploring new clinical applications and blazing a trail that the broader clinical community could follow. This interdisciplinary approach was key to the success of this technology.
      In MIT Researchers Dr. James Fujimoto and Mr. Eric Swanson Awarded the 2012 António Champalimaud Vision Award
    6. OCT has the advantage that it can image 1 or 2 millimeters below the surface with high resolution, noninvasively...Increased imaging speed is important; it allows broader coverage or improved resolution...the concept is not that the technology is trying to diagnose the cancer per se, since excisional biopsies do that well...Instead, it is coupling 3D OCT scanning across the sampling area with standard biopsies.
      In Optical Tomography May Aid 3D Cancer Diagnostics
    7. Ultrahigh-speed imaging is important because it enables the acquisition of large three-dimensional volumetric data sets with micron-scale resolution.
      In New High-speed 3-D Imaging System Holds Potential for Improved Cancer Screening
    8. Excisional biopsy is one of the gold standards for the diagnosis of cancer, but is a sampling procedure. If the biopsy is taken in a normal region of tissue and misses the cancer, the biopsy result is negative although the patient still has cancer.
      In New High-speed 3-D Imaging System Holds Potential for Improved Cancer Screening
    9. This device development is one of the major technical challenges in endoscopic OCT because probes must be small enough so that they can be introduced into the body, but still be able to scan an optical beam at high speeds...Increasing imaging speeds has also been an important research objective because high-resolution volumetric imaging requires very large amounts of data in order to cover appreciable regions of tissue, so rapid image acquisition rates are a powerful advantage.
      In New High-speed 3-D Imaging System Holds Potential for Improved Cancer Screening
    10. These long wavelengths have improved image penetration in scattering tissues...In ophthalmology, there is research interest in using swept-source OCT at 1000 nm because it is less sensitive to cataracts and enables imaging in scattering tissues, such as the choroid, the vascular network behind the retina.
      In Ophthalmic Lasers Expand from Surgery to Detection and Diagnosis