1. Jagat Narula

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    1. Mentioned In 30 Articles

    2. Atlas of Coronary Intravascular Optical Coherence Tomography (Textbook)

      Atlas of Coronary Intravascular Optical Coherence Tomography (Textbook)
      This atlas is a practical and fully illustrated guide to the use of intravascular OCT in diagnosis and treatment of coronary artery disease. It consists of two parts. The first part of the book provides a systematic introduction to coronary imaging with OCT. It describes how to interpret images and describes abnormal findings seen in atherosclerosis, complications after intervention, and stent assessment. The second part of the book presents real-life ...
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    3. Histopathological Differential Diagnosis of Optical Coherence Tomographic Image Interpretation After Stenting

      Histopathological Differential Diagnosis of Optical Coherence Tomographic Image Interpretation After Stenting
      Objectives The aim of this study was to identify histological features that correlate with terms commonly used to describe optical coherence tomographic (OCT) and optical frequency-domain imaging (OFDI) images of stented vessels, by means of a histopathological validation study using stented human coronary arteries. Background OCT imaging and OFDI are used to evaluate vascular responses to stent implantation. Descriptive terms such as peristrut low attenuation and heterogeneous have been used ...
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    4. Plaque Morphology Predictors of Side Branch Occlusion After Main Vessel Stenting in Coronary Bifurcation Lesions Optical Coherence Tomography Imaging Study

      Plaque Morphology Predictors of Side Branch Occlusion After Main Vessel Stenting in Coronary Bifurcation Lesions Optical Coherence Tomography Imaging Study
      Side branch (SB) occlusion remains a major complication of bifurcation lesion treatment. Although plaque and carina shift are suggested as mechanisms of SB occlusion (1) , little is known about underlying plaque morphology and composition of the main vessel (MV) and its potential impact on SB occlusion after MV stenting. Optical coherence tomography (OCT) allows precise evaluation of plaque characteristics, and dedicated bifurcation 3-dimensional (3D) quantitative coronary angiography (QCA) software permits ...
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    5. Multimodality Intravascular Imaging to Evaluate Sex Differences in Plaque Morphology in Stable CAD

      Multimodality Intravascular Imaging to Evaluate Sex Differences in Plaque Morphology in Stable CAD
      Objectives The aim of this study was to evaluate sex differences in plaque morphology in stable coronary artery disease (CAD) patients using a multimodality intravascular imaging approach. Background Differences in atherosclerotic burden and plaque morphology between men and women is a focus of treatment and preventative measures. Methods We retrospectively analyzed data from 383 patients with stable CAD who were referred for angiography and underwent optical coherence tomography. Among them ...
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    6. Multimodality Intravascular Imaging to Evaluate Sex Differences in Plaque Morphology in Stable CAD

      Multimodality Intravascular Imaging to Evaluate Sex Differences in Plaque Morphology in Stable CAD
      OBJECTIVES: The aim of this study was to evaluate sex differences in plaque morphology in stable coronary artery disease (CAD) patients using a multimodality intravascular imaging approach. BACKGROUND: Differences in atherosclerotic burden and plaque morphology between men and women is a focus of treatment and preventative measures. METHODS: We retrospectively analyzed data from 383 patients with stable CAD who were referred for angiography and underwent optical coherence tomography. Among them ...
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    7. Plaque morphology predictors of side branch occlusion after provisional stenting in coronary bifurcation lesion: Results of optical coherence tomography bifurcation study (ORBID)

      Plaque morphology predictors of side branch occlusion after provisional stenting in coronary bifurcation lesion: Results of optical coherence tomography bifurcation study (ORBID)
      Objectives The aim of this study was to identify the predictors of side branch (SB) ostial stenosis developed after provisional stenting of the main vessel (MV) using optical coherence tomography (OCT). Background Provisional stenting remains the main approach to treatment of bifurcation lesions; however, it may result in the narrowing of SB ostium. There is little information about underlying plaque morphology of the MV lesion and its potential impact on ...
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    8. Serial optical coherence tomography imaging of ACS-causing culprit plaques

      Serial optical coherence tomography imaging of ACS-causing culprit plaques
      Aims: The aim of this study was to understand better the mechanisms of repair of plaque complications causing acute coronary syndrome. Methods and results: We used OCT in the acute phase and at follow-up (one to seven months) to investigate the plaque healing in 10 culprit plaques: five ruptured fibrous cap (RFC) and five intact fibrous cap (IFC) which were not treated with stent deployment and caused ST-segment elevation myocardial ...
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    9. Multimodality Intravascular Imaging to Predict Periprocedural Myocardial Infarction During Percutaneous Coronary Intervention

      Multimodality Intravascular Imaging to Predict Periprocedural Myocardial Infarction During Percutaneous Coronary Intervention
      Objectives The aim of this study is to compare the relative merits of optical coherence tomography (OCT), intravascular ultrasound (IVUS), and near infrared spectroscopy (NIRS) in patients with coronary artery disease for the prediction of periprocedural myocardial infarction (MI). Background Although several individual intravascular imaging modalities have been employed to predict periprocedural MI, it is unclear which of the imaging tools would best allow prediction of this complication. Methods We ...
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    10. Matching human pathology is essential for validating OCT imaging to detect high-risk plaques

      Comment "As my comments in Nature Cardiology Reviews show, I strongly disagree with many aspects of the article Otsuka et al. ..." - mebrezin
      Matching human pathology is essential for validating OCT imaging to detect high-risk plaques
      We thank Mark Brezinski for his Correspondence ( Capabilities, limitations, and misconceptions of using OCT to assess vulnerable plaques . Nat. Rev. Cardiol. doi:10.1038/nrcardio.2014.62-c1 ) 1 on our Review ( Clinical classification of plaque morphology in coronary disease . Nat. Rev. Cardiol. 11 , 379 389 ; 2014 ), 2 and for his comments and clarifications. We agree that the phenomenon
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    11. Clinical classification of plaque morphology in coronary disease

      Clinical classification of plaque morphology in coronary disease
      In published post-mortem pathological studies, more than two-thirds of acute coronary events are associated with the rupture of lipid-rich, voluminous, and outwardly remodelled plaques covered by attenuated and inflamed fibrous caps in the proximal part of coronary arteries. Superficial erosion of the plaques is responsible for most of the remaining events; the eroded plaques usually do not demonstrate much lipid burden, do not have thin fibrous caps, are not positively ...
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    12. Integrated IVUS-OCT for Real-Time Imaging of Coronary Atherosclerosis

      Integrated IVUS-OCT for Real-Time Imaging of Coronary Atherosclerosis
      Accurate assessment of atherosclerotic plaque characteristics and the subsequent tailoring of optimal therapy holds great promise for preventing acute coronary syndromes (ACS) and life-threatening sequelae 1 . Combined use of optical coherence tomography (OCT) and intravascular ultrasound (IVUS) was proposed as a potential method for accurate assessment of plaque characteristics and vulnerability ( 2 , ). However, significant challenges remain in trying to adapt an integrated OCT-IVUS system for clinical applications. We report here ...
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    13. Comprehensive overview of definitions for optical coherence tomography-based plaque and stent analyses

      Comprehensive overview of definitions for optical coherence tomography-based plaque and stent analyses
      Optical coherence tomography (OCT) is the current state-of-the-art intracoronary imaging modality that allows visualization of detailed morphological characteristics of both atherosclerotic plaque and stent. So far, three expert review documents have been released for standardization of OCT image analysis. In the real world, a variety of definitions are being used by different groups and by different core laboratories to analyze OCT findings because of different clinical/procedural contexts in which ...
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    14. 1-15 of 30 1 2 »
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  2. About Jagat Narula

    Jagat Narula

    Jagat Narula is a cardiologist at the Mount Sinai School of Medicine in New York.  Jagat Narula is also with the University of California, Irvine Medical Center.