1. Institute of Applied Physics

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    1. Mentioned In 146 Articles

    2. Application of Phase Correction for Compensation of Motion Artifacts in Spectral-Domain Optical Coherence Tomography

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      Application of Phase Correction for Compensation of Motion Artifacts in Spectral-Domain Optical Coherence Tomography
      The application of computational methods to correct distortions in spectral-domain optical coherence tomography due to fast probe movements relative to a studied object is described. This technique is intended for use in endoscopy or in the study of external biological tissues using a handheld probe. The effectiveness of the method was confirmed experimentally.
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      Mentions: Institute of Applied Physics Grigory V. Gelikonov Valentin M. Gelikonov

    3. Low-scattering volumes visualisation from optical coherence tomography data and its applications in otolaryngology

      Explore IOPscience Otolaryngology
      Low-scattering volumes visualisation from optical coherence tomography data and its applications in otolaryngology
      The method for visualization of the low-scattering objects inside the bulk of the high-scattering tissue is presented. The method can contrast the low-scattering object of interest not only from the high scattering surroundings but from the noise region below the tissue image as well. The proposed method was applied for the visualization of the rodent and human cochlea volume.
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      Mentions: Institute of Applied Physics Grigory V. Gelikonov Valentin M. Gelikonov

    4. Numerical method for axial motion artifact correction in retinal spectral-domain optical coherence tomography

      Explore Home - Springer Ophthalmology
      Numerical method for axial motion artifact correction in retinal spectral-domain optical coherence tomography
      A numerical method that compensates image distortions caused by random fluctuations of the distance to an object in spectral-domain optical coherence tomography (SD OCT) has been proposed and verified experimentally. The proposed method is based on the analysis of the phase shifts between adjacent scans that are caused by micrometer-scale displacements and the subsequent compensation for the displacements through phase-frequency correction in the spectral space. The efficiency of the method ...
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      Mentions: Nizhny Novgorod State Medical Academy Institute of Applied Physics Grigory V. Gelikonov

    6. Optical coherence angiography for pre-treatment assessment and treatment monitoring following photodynamic therapy: a basal cell carcinoma patient study

      Explore Nature Publishing Group Dermatology
      Optical coherence angiography for pre-treatment assessment and treatment monitoring following photodynamic therapy: a basal cell carcinoma patient study
      Microvascular networks of human basal cell carcinomas (BCC) and surrounding skin were assessed with optical coherence angiography (OCA) in conjunction with photodynamic therapy (PDT). OCA images were collected and analyzed in 31 lesions pre-treatment, and immediately/24hours/312 months post-treatment. Pre-treatment OCA enabled differentiation between prevalent subtypes of BCC (nodular and superficial) and nodular-with-necrotic-core BCC subtypes with a diagnostic accuracy of 78%; this can facilitate more accurate biopsy reducing sampling ...
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      Mentions: University of Toronto Felix I. Feldchtein I. Alex Vitkin

    7. Spectral domain optical coherence tomography based imaging biomarkers for diabetic retinopathy

      Explore Home - Springer Ophthalmology
      Spectral domain optical coherence tomography based imaging biomarkers for diabetic retinopathy
      To evaluate the role of central subfield thickness (CST), cube average thickness (CAT), and cube volume (CV) as imaging biomarkers for severity of diabetic retinopathy within the ETDRS-based grades of retinopathy using spectral domain optical coherence tomography (SD-OCT). This study aims to evaluate the role of macular CST, CAT, and CV on SD-OCT as imaging biomarkers for severity of DR. One hundred ninety-four consecutive cases of type 2 diabetes mellitus ...
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      Mentions: Institute of Applied Physics Sandeep Saxena

    8. Full-Field Optical Coherence Tomography Based on a MII-4 Microprofilometer Using Microlenses with Air Immersion

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      Full-Field Optical Coherence Tomography Based on a MII-4 Microprofilometer Using Microlenses with Air Immersion
      A modernized Linnik microprofilometer (MII-4) allowing the performing of tomographic investigation of transparent and relatively turbid media by the methods of low-coherence interferometry has been presented. The design of the reference channel of the standard MII-4 has been revised. A dynamic adjustment of the reference arm length has been added to compensate for the effect of divergence between focal and coherent volumes, as well as spherical aberration that occurs when ...
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      Mentions: Institute of Applied Physics Saratov State University Valery V. Tuchin

    9. Elimination of Artifacts Caused by the Nonidentity of Parallel Signal-Reception Channels in Spectral Domain Optical Coherence Tomography

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      Elimination of Artifacts Caused by the Nonidentity of Parallel Signal-Reception Channels in Spectral Domain Optical Coherence Tomography
      We study the causes of artifact appearance in the images obtained by the method of spectral domain optical coherence tomography with parallel reception of the optical-spectrum components, which are manifested in repetition and overlay of the structural elements of the images of the studied medium with a shift in depth. It is shown that nonidentity of the transfer characteristics of the channels of the multichannel photoreceiving elements is one of ...
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      Mentions: Institute of Applied Physics Grigory V. Gelikonov Valentin M. Gelikonov

    10. Compensation for the Influence of Fluctuations in the Distance to the Object During Noncontact Probing in Spectral Domain Optical Coherence Tomography

      Explore Home - Springer Otolaryngology
      Compensation for the Influence of Fluctuations in the Distance to the Object During Noncontact Probing in Spectral Domain Optical Coherence Tomography
      We propose and experimentally test a numerical method for correction of the influence of fluctuations in the distance to objects during noncontact probing in optical coherence tomography. The method is based on the analysis of phase shifts of the neighboring scans, which are due to microscale displacements, and further compensation for these displacements by using phasefrequency correction in the spectral domain. Unlike the known correlation methods, the proposed method does ...
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      Mentions: Institute of Applied Physics Grigory V. Gelikonov Valentin M. Gelikonov

    11. Analysis of low-scattering regions in optical coherence tomography

      Explore OSA | OSA Publishing Neurology , Oncology
      Analysis of low-scattering regions in optical coherence tomography
      Analysis of semi-transparent low scattering biological structures in optical coherence tomography (OCT) has been actively pursued in the context of lymphatic imaging, with most approaches relying on the relative absence of signal as a means of detection. Here we present an alternate methodology based on spatial speckle statistics, utilizing the similarity of a distribution of given voxel intensities to the power distribution function of pure noise, to visualize the low-scattering ...
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      Mentions: Guillermo J. Tearney Brett E. Bouma B. Hyle Park

    12. Optical coefficients as tools for increasing the optical coherence tomography contrast for normal brain visualization and glioblastoma detection

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      Optical coefficients as tools for increasing the optical coherence tomography contrast for normal brain visualization and glioblastoma detection
      The methods used for digital processing of optical coherence tomography (OCT) and crosspolarization (CP) OCT images are focused on improving the contrast ratio of native structural OCT images. Such advances are particularly important for the intraoperative detection of glioma margins where the visual assessment of OCT images can be difficult and lead to errors. The aim of the study was to investigate the application of optical coefficients obtained from CP ...
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      Mentions: Institute of Applied Physics Grigory V. Gelikonov Elena V. Zagaynova

    13. Improving the Transverse Resolution of Optical Coherence Tomography with a Finite Impulse Response Filter and a Series of Numerically Refocused Images

      Explore Журнал СТМ
      Improving the Transverse Resolution of Optical Coherence Tomography with a Finite Impulse Response Filter and a Series of Numerically Refocused Images
      Among the numerous methods for improving the informative value of the optical coherence tomography (OCT), a special place is taken by the methods for increasing the spatial resolution of the resulting images. Increasing the resolution allows one to identify more clinically significant structures in OCT images and thus improve the diagnostic value of OCT. Since the transverse resolution of OCT images is determined by the physical principles different from those ...
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      Mentions: Institute of Applied Physics Grigory V. Gelikonov Valentin M. Gelikonov

    14. An Experimentally Trained Noise Filtration Method of Optical Coherence Tomography Signals

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      An Experimentally Trained Noise Filtration Method of Optical Coherence Tomography Signals
      A method for wavelet filtration procedure training for optical coherence tomography (OCT) images using the experimental measurements of test objects that were constructed by means of water solutions of monodisperse nanoparticles and several microscopic inclusions has been described in the present paper. The choice of test-object parameters (concentration of water solution, size of nanoparticles, and shape, dimensions, and mutual position of inclusions) has allowed the modeling of various working conditions ...
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      Mentions: Institute of Applied Physics Saratov State University Valery V. Tuchin

    15. En-face optical coherence tomography/fluorescence endomicroscopy for minimally invasive imaging using a robotic scanner

      Explore SPIE Digital Library Dermatology , Pulmonology
      En-face optical coherence tomography/fluorescence endomicroscopy for minimally invasive imaging using a robotic scanner
      We report a compact rigid instrument capable of delivering en-face optical coherence tomography (OCT) images alongside (epi)-fluorescence endomicroscopy (FEM) images by means of a robotic scanning device. Two working imaging channels are included: one for a one-dimensional scanning, forward-viewing OCT probe and another for a fiber bundle used for the FEM system. The robotic scanning system provides the second axis of scanning for the OCT channel while allowing the ...
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      Mentions: Imperial College London Adrian G. Podoleanu University of Kent

    16. Application of the Method of Multiple Mutual Synchronization of Parallel Computational Threads in Spectral-Domain Optical Coherent Tomography Systems

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      Application of the Method of Multiple Mutual Synchronization of Parallel Computational Threads in Spectral-Domain Optical Coherent Tomography Systems
      A method for multiple mutual synchronization of parallel computational threads, which is used in spectral-domain optical coherence tomography systems, is described. Due to the effective distribution of the computational load in the central processor of the control computer, the method made it possible to perform procedures for calculating tomographic slices of the subsurface tissues of a living organism in real time. The application of this method made it possible to ...
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      Mentions: Institute of Applied Physics
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  4. About Institute of Applied Physics

    Institute of Applied Physics

    Institute of Applied Physics of the Russian Academy of Sciences (IAP RAS) was created by a Decree of the Soviet Government on July 28, 1976. Annually the IAP RAS performs about 350 scientific projects, funded by federal special programs, academic, industry, international and other programs and projects. Among the most prominent achievements of the Institute of Applied Physics RAS are the invention of gyrotrons and gyroklystrons and their upgrading to a high technical level, the development of effective methods to convert and transport powerful electromagnetic radiation, the elaboration of physical principles for excitation and reception of low-frequency sound fields in the ocean and the creation of hardware for hydroacoustics and long-term acoustical monitoring in the ocean, complexes for research of noise radiation characteristics of moving objects, the development of high-rate growth and precision processing of water-soluble crystals, developmet of optical coherent tomography to image biotissue structures and designing an optical tomograph for medical diagnostics of human internal organs  See IAP RAS OCT link HERE.

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