1. Indiana University

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    1. Mentioned In 99 Articles

    2. Comparison of retinal nerve fiber layer and macular thickness for discriminating primary open-angle glaucoma and normal-tension glaucoma using optical coherence tomography

      Comparison of retinal nerve fiber layer and macular thickness for discriminating primary open-angle glaucoma and normal-tension glaucoma using optical coherence tomography
      Purpose The aim of this study was to evaluate the discrimination capabilities of macular and peripapillary retinal nerve fiber layer (pRNFL) thickness parameters as measured using spectral domain optical coherence tomography (SD-OCT) between primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG). Methods A total of 90 subjects were enrolled: 30 healthy subjects, 30 subjects with POAG and 30 subjects with NTG, consecutively. Retinal nerve fiber layer thickness, macular thickness and ...
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    3. Imaging human retinal pigment epithelium cells using adaptive optics optical coherence tomography

      Imaging human retinal pigment epithelium cells using adaptive optics optical coherence tomography
      Retinal pigment epithelium (RPE) cells are vital to health of the outer retina, but are often compromised in ageing and major ocular diseases that lead to blindness. Early manifestation of RPE disruption occurs at the cellular level, and while biomarkers at this scale hold considerable promise, RPE cells have proven extremely challenging to image in the living human eye. We present a novel method based on optical coherence tomography (OCT ...
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    4. Advanced Imaging in Barrett’s Esophagus

      Advanced Imaging in Barrett’s Esophagus
      Enhanced imaging technologies such as narrow band imaging, flexible spectral imaging color enhancement, i-Scan, confocal laser endomicroscopy, and optical coherence tomography are readily available for use by endoscopists in routine clinical practice. In November 2014, the American Gastroenterological Associations Center for GI Innovation and Technology conducted a 2-day workshop to discuss endoscopic image enhancement technologies, focusing on their role in 2 specific clinical conditions (colon polyps and Barretts esophagus) and ...
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    5. A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization

      A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization
      Purpose: Therapeutic efficacy is routinely assessed by measurement of lesion size using flatmounted choroids and confocal microscopy in the laser-induced choroidal neovascularization (L-CNV) rodent model. We investigated whether optical coherence tomography (OCT) quantification, using an ellipsoid volume measurement, was comparable to standard ex vivo evaluation methods for this model and whether this approach could be used to monitor treatment-related lesion changes. Methods: Bruch's membrane was ruptured by argon laser ...
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    6. Optical coherence tomography enables imaging of tumor initiation in the TAg-RB mouse model of retinoblastoma

      Optical coherence tomography enables imaging of tumor initiation in the TAg-RB mouse model of retinoblastoma
      Purpose: Retinoblastoma is the most common primary intraocular malignancy in children. Although significant advances in treatment have decreased mortality in recent years, morbidity continues to be associated with these therapies, and therefore, there is a pressing need for new therapeutic options. Transgenic mouse models are popular for testing new therapeutics as well as studying the pathophysiology of retinoblastoma. The T-antigen retinoblastoma (TAg-RB) model has close molecular and histological resemblance to ...
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    7. Imaging modal content of cone photoreceptors using adaptive optics optical coherence tomography

      Imaging modal content of cone photoreceptors using adaptive optics optical coherence tomography
      It has been long established that photoreceptors capture light based on the principles of optical waveguiding. Yet after decades of experimental and theoretical investigations considerable uncertainty remains, even for the most basic prediction as to whether photoreceptors support more than a single waveguide mode. To test for modal behavior in human cone photoreceptors, we took advantage of adaptive-optics optical coherence tomography (AO-OCT, c=785 nm) to noninvasively image in three ...
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    8. Feature Of The Week 01/11/15: Indiana University Demonstrates Adaptive Optics Optical Coherence Tomography at 1 MHz

      Feature Of The Week 01/11/15: Indiana University Demonstrates Adaptive Optics Optical Coherence Tomography at 1 MHz
      ... in the 700 to 915 nm spectral band. For more information see recent Article . Courtesy of Omer Kocaoglu from Indiana University . Since its first report in 1991, OCT has undergone tremendous advances in almost all aspec...
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    9. Eye Shape Using Partial Coherence Interferometry, Autorefraction, and SD-OCT

      Eye Shape Using Partial Coherence Interferometry, Autorefraction, and SD-OCT
      Purpose: Peripheral refraction and retinal shape may influence refractive development. Peripheral refraction has been shown to have a high degree of variability and can take considerable time to perform. Spectral domain optical coherence tomography (SD-OCT) and peripheral axial length measures may be more reliable, assuming that the retinal position is more important than the peripheral optics of the lens/cornea. Methods: Seventy-nine subjects' right eyes were imaged for this study ...
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    10. Adaptive-optics optical coherence tomography processing using a graphics processing unit

      Adaptive-optics optical coherence tomography processing using a graphics processing unit
      Graphics processing units are increasingly being used for scientific computing for their powerful parallel processing abilities, and moderate price compared to super computers and computing grids. In this paper we have used a general purpose graphics processing unit to process adaptive-optics optical coherence tomography (AOOCT) images in real time. Increasing the processing speed of AOOCT is an essential step in moving the super high resolution technology closer to clinical viability.
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    11. Handbook of Retinal OCT: Optical Coherence Tomography

      Handbook of Retinal OCT: Optical Coherence Tomography
      In a little over two decades, optical coherence tomography (OCT) has become an indispensable imaging diagnostic service in eye care. This dramatic rise has been accompanied by a stream of OCT books from hardcore engineering to clinical use. It is on this front that the Handbook of Retinal OCT makes its debut. The book is an authoritative OCT guide put together by a team of international leaders in the eye ...
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    12. 31-45 of 99 « 1 2 3 4 5 6 7 »
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  2. About Indiana University

    Indiana University

    Indiana University, founded in 1820, is a nine-campus university system in the state of Indiana. The IU system includes the following campuses: Indiana University in Bloomington (flagship campus), Indiana University East in Richmond,Indiana University Kokomo in Kokomo, Indiana University Northwest in Gary,Indiana University South Bend in South Bend, Indiana University Southeast in New Albany.