1. Indiana University

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    1. Mentioned In 95 Articles

    2. A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization

      A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization
      Purpose: Therapeutic efficacy is routinely assessed by measurement of lesion size using flatmounted choroids and confocal microscopy in the laser-induced choroidal neovascularization (L-CNV) rodent model. We investigated whether optical coherence tomography (OCT) quantification, using an ellipsoid volume measurement, was comparable to standard ex vivo evaluation methods for this model and whether this approach could be used to monitor treatment-related lesion changes. Methods: Bruch's membrane was ruptured by argon laser ...
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    3. Optical coherence tomography enables imaging of tumor initiation in the TAg-RB mouse model of retinoblastoma

      Optical coherence tomography enables imaging of tumor initiation in the TAg-RB mouse model of retinoblastoma
      Purpose: Retinoblastoma is the most common primary intraocular malignancy in children. Although significant advances in treatment have decreased mortality in recent years, morbidity continues to be associated with these therapies, and therefore, there is a pressing need for new therapeutic options. Transgenic mouse models are popular for testing new therapeutics as well as studying the pathophysiology of retinoblastoma. The T-antigen retinoblastoma (TAg-RB) model has close molecular and histological resemblance to ...
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    4. Imaging modal content of cone photoreceptors using adaptive optics optical coherence tomography

      Imaging modal content of cone photoreceptors using adaptive optics optical coherence tomography
      It has been long established that photoreceptors capture light based on the principles of optical waveguiding. Yet after decades of experimental and theoretical investigations considerable uncertainty remains, even for the most basic prediction as to whether photoreceptors support more than a single waveguide mode. To test for modal behavior in human cone photoreceptors, we took advantage of adaptive-optics optical coherence tomography (AO-OCT, c=785 nm) to noninvasively image in three ...
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    5. Feature Of The Week 01/11/15: Indiana University Demonstrates Adaptive Optics Optical Coherence Tomography at 1 MHz

      Feature Of The Week 01/11/15: Indiana University Demonstrates Adaptive Optics Optical Coherence Tomography at 1 MHz
      ... in the 700 to 915 nm spectral band. For more information see recent Article . Courtesy of Omer Kocaoglu from Indiana University . Since its first report in 1991, OCT has undergone tremendous advances in almost all aspec...
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    6. Eye Shape Using Partial Coherence Interferometry, Autorefraction, and SD-OCT

      Eye Shape Using Partial Coherence Interferometry, Autorefraction, and SD-OCT
      Purpose: Peripheral refraction and retinal shape may influence refractive development. Peripheral refraction has been shown to have a high degree of variability and can take considerable time to perform. Spectral domain optical coherence tomography (SD-OCT) and peripheral axial length measures may be more reliable, assuming that the retinal position is more important than the peripheral optics of the lens/cornea. Methods: Seventy-nine subjects' right eyes were imaged for this study ...
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    7. Adaptive-optics optical coherence tomography processing using a graphics processing unit

      Adaptive-optics optical coherence tomography processing using a graphics processing unit
      Graphics processing units are increasingly being used for scientific computing for their powerful parallel processing abilities, and moderate price compared to super computers and computing grids. In this paper we have used a general purpose graphics processing unit to process adaptive-optics optical coherence tomography (AOOCT) images in real time. Increasing the processing speed of AOOCT is an essential step in moving the super high resolution technology closer to clinical viability.
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    8. Handbook of Retinal OCT: Optical Coherence Tomography

      Handbook of Retinal OCT: Optical Coherence Tomography
      In a little over two decades, optical coherence tomography (OCT) has become an indispensable imaging diagnostic service in eye care. This dramatic rise has been accompanied by a stream of OCT books from hardcore engineering to clinical use. It is on this front that the Handbook of Retinal OCT makes its debut. The book is an authoritative OCT guide put together by a team of international leaders in the eye ...
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    9. Novel Analytical Methods for Stratus OCT: Alignment of the Scan Circle

      Novel Analytical Methods for Stratus OCT: Alignment of the Scan Circle
      ABSTRACT: Measurement of retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (OCT) is commonly used in the detection and management of glaucoma. The Stratus OCT (Carl Zeiss Meditec, Inc., Dublin, CA) is widely used, but image acquisition is subject to artifacts, such as those caused by normal fixational eye movements, and this leads to unreliable measurements. Novel analytical methods have been developed to estimate the amount of misalignment ...
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    10. 31-45 of 95 « 1 2 3 4 5 6 7 »
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  2. About Indiana University

    Indiana University

    Indiana University, founded in 1820, is a nine-campus university system in the state of Indiana. The IU system includes the following campuses: Indiana University in Bloomington (flagship campus), Indiana University East in Richmond,Indiana University Kokomo in Kokomo, Indiana University Northwest in Gary,Indiana University South Bend in South Bend, Indiana University Southeast in New Albany.