1. Indiana University

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    1. Mentioned In 102 Articles

    2. Cellular Scale Imaging of Transparent Retinal Structures and Processes Using Adaptive Optics Optical Coherence Tomography

      Cellular Scale Imaging of Transparent Retinal Structures and Processes Using Adaptive Optics Optical Coherence Tomography
      High-resolution retinal imaging is revolutionizing how scientists and clinicians study the retina on the cellular scale. Its exquisite sensitivity enables time-lapse optical biopsies that capture minute changes in the structure and physiological processes of cells in the living eye. This information is increasingly used to detect disease onset and monitor disease progression during early stages, raising the possibility of personalized eye care. Powerful high-resolution imaging tools have been in development ...
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    3. Optic nerve head diurnal vessel density variations in glaucoma and ocular hypertension measured by optical coherence tomography angiography

      Optic nerve head diurnal vessel density variations in glaucoma and ocular hypertension measured by optical coherence tomography angiography
      Background/aims To evaluate diurnal variations in optic nerve head (ONH) vessel density assessed by optical coherence tomography angiography (OCT-A) in healthy subjects, ocular hypertension (OHT), and open-angle glaucoma (OAG) patients. Methods Forty subjects (OAG, 21; OHT, 6; healthy, 13) were assessed for vessel density percentage (VD%) and flow index in the ONH (NH VD%, NH index), and in the radial peripapillary capillary layer (RPC VD%, RPC index) at 9 ...
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    4. Quantitative assessment of human donor corneal endothelium with Gabor domain optical coherence microscopy

      Quantitative assessment of human donor corneal endothelium with Gabor domain optical coherence microscopy
      We report on a pathway for Gabor domain optical coherence microscopy (GD-OCM)-based metrology to assess the donors corneal endothelial layers ex vivo . Six corneas from the Lions Eye Bank at Albany and Rochester were imaged with GD-OCM. The raw 3-D images of the curved corneas were flattened using custom software to enhance the 2-D visualization of endothelial cells (ECs); then the ECs within a circle of 500-m-diameter were analyzed ...
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    5. In vitro longitudinal evaluation of enamel wear by cross-polarization optical coherence tomography

      In vitro longitudinal evaluation of enamel wear by cross-polarization optical coherence tomography
      Objectives Enamel thickness determination by Cross-Polarization Optical Coherence Tomography (CP-OCT) is a promising approach for quantitative monitoring of tooth wear progression. This study evaluated the ability of CP-OCT to quantify the thickness of natural enamel before, during and after tooth wear simulation. Materials and Methods Natural, unpolished human dental enamel slabs were submitted to five wear stages (Wear 1: to level the surfaces; Wear 2 to Wear 5: 0.05 ...
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    6. Capabilities of Gabor-domain optical coherence microscopy for the assessment of corneal disease

      Capabilities of Gabor-domain optical coherence microscopy for the assessment of corneal disease
      To identify the microstructural modification of the corneal layers during the course of the disease, optical technologies have been pushing the boundary of innovation to achieve cellular resolution of deep layers of the cornea. Gabor-domain optical coherence microscopy (GD-OCM), an optical coherence tomography-based technique that can achieve an isotropic of 2-m resolution over a volume of 1mm1mm1.2mm, was developed to investigate the microstructural modifications of corneal layers in four ...
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    7. Research Associate / Postdoctoral Fellow in Adaptive Optics and Optical Coherence Tomography at Indiana University

      Research Associate / Postdoctoral Fellow in Adaptive Optics and Optical Coherence Tomography at Indiana University
      ... Bloomington, IN 47405. For more information see this link:  http://www.opt.indiana.edu/dtmiller/Index.aspx Indiana University is an equal employment and affirmative action employer and a provider of ADA services. All ...
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    8. Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography

      Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography
      We employ optical coherence tomography (OCT) and optical coherence microscopy (OCM) to study conjunctival lymphatics in porcine eyes ex vivo . This study is a precursor to the development of in vivo imaging of the collecting lymphatics for potentially guiding and monitoring glaucoma filtration surgery. OCT scans at 1300 nm and higher‐resolution OCM scans at 785 nm reveal the lymphatic vessels via their optical transparency. Equivalent signal characteristics are also ...
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  2. About Indiana University

    Indiana University

    Indiana University, founded in 1820, is a nine-campus university system in the state of Indiana. The IU system includes the following campuses: Indiana University in Bloomington (flagship campus), Indiana University East in Richmond,Indiana University Kokomo in Kokomo, Indiana University Northwest in Gary,Indiana University South Bend in South Bend, Indiana University Southeast in New Albany.