1. Imperial College London

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    1. Mentioned In 115 Articles

    2. What are the PROSPECTs and clinical implications of vulnerable plaque?

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      What are the PROSPECTs and clinical implications of vulnerable plaque?
      Despite the fact that it has been three decades since James Muller and his colleagues first proposed the concept of vulnerable plaque 1 and 18 years since Naghavi et al. published their consensus document summarizing the concepts behind vulnerable patients and vulnerable plaques, including classifications for clinical and pathological evaluation, 2 , 3 we still have much to learn about the clinical implications of vulnerable plaque ( Graphical Abstract ). Feasibility of vulnerable ...
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      Mentions: Imperial College London Cardiovascular Research Foundation

    3. Stent type identification with optical coherence tomography: novelty in search of clinical application

      Explore eurointervention.pcronline.com Cardiology
      Stent type identification with optical coherence tomography: novelty in search of clinical application
      Over the last three decades, developments in intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have advanced our understanding of coronary disease pathophysiology and improved outcomes of percutaneous coronary intervention (PCI) procedures. Although in daily clinical practice most imaging utilisation relies on a simple, two-dimensional display of cross-sectional coronary images, real-time three-dimensional (3D) visualisation of coronary arteries with OCT offers advantages over and above simple vessel sizing and plaque characterisation ...
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      Mentions: Imperial College London

    4. Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19

      Explore Home - ClinicalTrials.gov Pulmonology , Clinical Trials
      Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19
      The purpose of this research project is to study small airways physiological function in patients with chronic obstructive lung disease or COVID-19 and explore the relationship with in-vivo microanatomical small airway structure as measured by OCT. Correlating endobronchial assessment with multiple breath nitrogen washout and impulse oscillometry will allow the characterisation of the relationship between small airway structural findings and these validated investigations. A small volume lung wash, endobronchial brushings ...
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      Mentions: Imperial College London

    6. Recent advances in imaging technologies for assessment of retinal diseases

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      Recent advances in imaging technologies for assessment of retinal diseases
      Introduction Retinal imaging is a key investigation in ophthalmology. New devices continue to be created to keep up with the demand for better imaging modalities in this field. This review looks to highlight current trends and the future of retinal imaging. Areas covered This review looks at the advances in topographical imaging, photoacoustic microscopy, optical coherence tomography and molecular imaging. There is future scoping Expert opinion Retinal imaging continues to ...
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      Mentions: Imperial College London

    7. Utility of Multimodality Intravascular Imaging and the Local Hemodynamic Forces to Predict Atherosclerotic Disease Progression

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      Utility of Multimodality Intravascular Imaging and the Local Hemodynamic Forces to Predict Atherosclerotic Disease Progression
      Objectives This study sought to examine the utility of multimodality intravascular imaging and of the endothelial shear stress (ESS) distribution to predict atherosclerotic evolution. Background There is robust evidence that intravascular ultrasound (IVUS)-derived plaque characteristics and ESS distribution can predict, with however limited accuracy, atherosclerotic evolution; nevertheless, it is yet unclear whether multimodality imaging and ESS mapping enable more accurate prediction of coronary plaque progression. Methods A total of ...
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      Mentions: Imperial College London University College London University of Copenhagen

    9. NTU and SERI launch joint laboratory to develop advanced ocular imaging technologies

      Explore Optical Coherence Tomography News Ophthalmology , Partnership
      NTU and SERI launch joint laboratory to develop advanced ocular imaging technologies
      ...d Graduate colleges. It also has a medical school, the Lee Kong Chian School of Medicine, set up jointly with Imperial College London. NTU is also home to world-class autonomous institutes – the National Institute of Edu...
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      Mentions: Imperial College London Singapore Eye Research Institute Nanyang Technological University

    10. The year in cardiology: acute coronary syndromes: The year in cardiology 2019

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      The year in cardiology: acute coronary syndromes: The year in cardiology 2019
      The mechanisms and the pathologic substrate of plaque erosion and plaque fissure are different. Indeed, plaques complicated by erosion tend to be matrix-rich, lipid-poor, and usually lack prominent macrophage collections, unlike plaques that rupture, which characteristically have thin fibrous caps, large lipid pools, and abundant foam cells. 9 In a prospective study in 211 patients with STEMI who underwent pre-intervention optical coherence tomography (OCT) examination for the culprit lesion, Tan ...
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      Mentions: Imperial College London Boston Scientific Abbott

    11. Efficacy and Reproducibility of Attenuation-Compensated Optical Coherence Tomography for Assessing External Elastic Membrane Border and Plaque Composition in Native and Stented Segments ― An In Vivo and Histology-Based Study ―

      Explore jstage.jst.go.jp Cardiology
      Efficacy and Reproducibility of Attenuation-Compensated Optical Coherence Tomography for Assessing External Elastic Membrane Border and Plaque Composition in Native and Stented Segments ― An In Vivo and Histology-Based Study ―
      Background: Attenuation-compensated (AC) technique was recently introduced to improve the plaque characterization of optical coherence tomography (OCT). Histological validation demonstrated promising results but the efficacy and reproducibility of this technique for assessing in-vivo tissue composition remains unclear. Methods and Results: OCT images portraying native (n=200) and stented (n=200) segments and 31 histological cross-sections were analyzed. AC-OCT appeared superior to conventional (C)-OCT in detecting the external elastic lamina ...
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      Mentions: Imperial College London Leiden University University College London

    12. Neointimal characteristics comparison between biodegradable-polymer and durable-polymer drug-eluting stents: 3-month follow-up optical coherence tomography light property analysis from the RESTORE registry

      Explore Home - Springer Cardiology
      Neointimal characteristics comparison between biodegradable-polymer and durable-polymer drug-eluting stents: 3-month follow-up optical coherence tomography light property analysis from the RESTORE registry
      We aimed to quantitatively assess a possible difference of the neointimal quality between biodegradable polymer- (BP-) and durable polymer drug-eluting stents (DP-DESs). We conducted a single-center all-comer prospective cohort study: the RESTORE registry (UMIN000033009). All patients who received successful OCT examination at planned 3-month follow-up after DES implantation were analyzed. Study population was divided into 2 groups, BP-DES versus DP-DES groups. We evaluated standard OCT variables, coverage percent, and the ...
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      Mentions: Imperial College London Leiden University Osaka University

    13. Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent

      Explore eurointervention.pcronline.com Cardiology
      Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent
      This consensus document is the second of two reports summarizing the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) on the clinical use of intracoronary imaging including intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near infrared spectroscopy (NIRS)-IVUS. Beyond guidance of stent selection and optimization of deployment, invasive imaging facilitates angiographic interpretation and may guide treatment in acute coronary syndrome. Intravascular ...
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      Mentions: Imperial College London Columbia University Cardiovascular Research Foundation

    14. Deep learning based early stage diabetic retinopathy detection using optical coherence tomography

      Explore ScienceDirect Ophthalmology
      Deep learning based early stage diabetic retinopathy detection using optical coherence tomography
      Diabetic retinopathy (DR) is one of the leading causes of preventable blindness globally. Performing retinal examinations on all diabetic patients is an unmet need, and detection at an early stage can provide better control of the disease. The objective of this study is to provide an optical coherence tomography (OCT) image based diagnostic technology for automated early DR diagnosis, including at both grades 0 and 1. This work can help ...
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      Mentions: Imperial College London Wenzhou Medical College

    16. En-face optical coherence tomography/fluorescence endomicroscopy for minimally invasive imaging using a robotic scanner

      Explore SPIE Digital Library Dermatology , Pulmonology
      En-face optical coherence tomography/fluorescence endomicroscopy for minimally invasive imaging using a robotic scanner
      We report a compact rigid instrument capable of delivering en-face optical coherence tomography (OCT) images alongside (epi)-fluorescence endomicroscopy (FEM) images by means of a robotic scanning device. Two working imaging channels are included: one for a one-dimensional scanning, forward-viewing OCT probe and another for a fiber bundle used for the FEM system. The robotic scanning system provides the second axis of scanning for the OCT channel while allowing the ...
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      Mentions: Imperial College London University of Kent Institute of Applied Physics
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  4. About Imperial College London

    Imperial College London

    Imperial College London is consistently rated amongst the world's best universities, Imperial College London is a science-based institution with a reputation for excellence in teaching and research. Imperial's main campus is located in South Kensington in central London. Formerly a constituent college of the University of London, Imperial became independent of the university on 8 July 2007, the 100th anniversary of its founding.

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