1. Imperial College London

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    1. Mentioned In 85 Articles

    2. In vivo multiphoton microscopy using a handheld scanner with lateral and axial motion compensation

      Explore Wiley Online Library Microscopy , Ophthalmology
      In vivo multiphoton microscopy using a handheld scanner with lateral and axial motion compensation
      This paper reports a handheld multiphoton fluorescence microscope designed for clinical imaging that incorporates axial motion compensation and lateral image stabilization. Spectral domain optical coherence tomography is employed to track the axial position of the skin surface, and lateral motion compensation is realised by imaging the speckle pattern arising from the optical coherence tomography beam illuminating the sample. Our system is able to correct lateral sample velocities of up to ...
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      Mentions: Imperial College London

    3. Opportunity Research Assistant/Associate in Biophotonics and Endoscopic Imaging at Imperial College London

      Explore Optical Coherence Tomography News Jobs & Studentships
      Opportunity Research Assistant/Associate in Biophotonics and Endoscopic Imaging at Imperial College London
      Job Title: Research Assistant/Associate in Biophotonics and Endoscopic Imaging Department/Division/Faculty: The Hamlyn Centre for Robotic Surgery in association with Department of Computing, Faculty of Engineering Department of Surgery and Cancer, Faculty of Medicine Advert: Research Assistant salary: 31,740 to 33,370 per annum Research Associate salary: 36,070 to 43,350 per annum S outh Kensington Campus Fixed term appointment until 31 st May 2019 Applicants ...
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      Mentions: Imperial College London Adrian G. Podoleanu University of Kent

    4. Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial

      Explore ResearchGate Cardiology
      Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial
      Aims: The purpose of this study was to assess the vascular response and vessel healing of overlapped Absorb scaffolds (Abbott Vascular, Santa Clara, CA, USA) compared to non-overlapped devices in human coronary arteries as assessed by optical coherence tomography (OCT) in the same treated segment. Methods and results: The ABSORB EXTEND (NCT01023789) trial is a prospective, single-arm, openlabel clinical study which enrolled 800 patients. The planned overlap OCT subgroup in ...
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      Mentions: Imperial College London University of Manchester Patrick W. Serruys

    5. Intracoronary optical coherence tomography: Clinical and research applications and intravascular imaging software overview

      Explore Wiley Online Library Cardiology
      Intracoronary optical coherence tomography: Clinical and research applications and intravascular imaging software overview
      By providing valuable information about the coronary artery wall and lumen, intravascular imaging may aid in optimizing interventional procedure results and thereby could improve clinical outcomes following percutaneous coronary intervention (PCI). Intravascular optical coherence tomography (OCT) is a light-based technology with a tissue penetration of approximately 1 to 3 mm and provides near histological resolution. It has emerged as a technological breakthrough in intravascular imaging with multiple clinical and research ...
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      Mentions: Imperial College London Leiden University University College London

    7. Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study

      Explore BMJ Open Cardiology , Clinical Trials
      Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study
      Introduction The mainstay treatment for reducing the symptoms of angina and long-term risk of heart attacks in patients with heart disease is stent implantation in the diseased coronary artery. While this procedure has revolutionised treatment, the incidence of secondary events remains a concern. These repeat events are thought to be due, in part, to continued enhanced platelet reactivity, endothelial dysfunction and ultimately restenosis of the stented artery. In this study ...
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      Mentions: Imperial College London

    8. Variability in the measurement of minimum fibrous cap thickness and reproducibility of fibroatheroma classification by optical coherence tomography using manual versus semi-automatic assessment

      Explore eurointervention.org Cardiology
      Variability in the measurement of minimum fibrous cap thickness and reproducibility of fibroatheroma classification by optical coherence tomography using manual versus semi-automatic assessment
      Aims: The minimum fibrous cap thickness (FCT) is considered a major criterion of coronary plaque vulnerability according to autopsy studies. We aimed to assess the reproducibility in the measurement of the optical coherence tomography (OCT)-detected minimum FCT and the agreement in the classification of thin-cap fibroatheroma (TCFA), by a software-based semi-automatic method compared with the manual method. Methods and results: A total of 50 frames with fibroatheromas (FA) were ...
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      Mentions: Imperial College London Case Western Reserve University Leiden University

    9. Minimal basilar membrane motion in low-frequency hearing

      Explore pnas.org Otolaryngology
      Minimal basilar membrane motion in low-frequency hearing
      To perceive speech, the brain relies on inputs from sensory cells located near the top of the spiral-shaped cochlea. This low-frequency region of the inner ear is anatomically difficult to access, and it has not previously been possible to study its mechanical response to sound in intact preparations. Here, we used optical coherence tomography to image sound-evoked vibration inside the intact cochlea. We show that low-frequency sound moves a small ...
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      Mentions: Imperial College London Oregon Health & Science University University of Washington

    11. Hybrid intravascular imaging: recent advances, technical considerations, and current applications in the study of plaque pathophysiology

      Explore Oxford Journals Cardiology
      Hybrid intravascular imaging: recent advances, technical considerations, and current applications in the study of plaque pathophysiology
      Cumulative evidence from histology-based studies demonstrate that the currently available intravascular imaging techniques have fundamental limitations that do not allow complete and detailed evaluation of plaque morphology and pathobiology, limiting the ability to accurately identify high-risk plaques. To overcome these drawbacks, new efforts are developing for data fusion methodologies and the design of hybrid, dual-probe catheters to enable accurate assessment of plaque characteristics, and reliable identification of high-risk lesions. Today ...
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      Mentions: Guillermo J. Tearney University of Toronto Imperial College London

    12. Bioresorption and Vessel Wall Integration of a Fully Bioresorbable Polymeric Everolimus-Eluting Scaffold Optical Coherence Tomography, Intravascular Ultrasound, and Histological Study in a Porcine Model With 4-Year Follow-Up

      Explore interventions.onlinejacc.org Cardiology
      Bioresorption and Vessel Wall Integration of a Fully Bioresorbable Polymeric Everolimus-Eluting Scaffold Optical Coherence Tomography, Intravascular Ultrasound, and Histological Study in a Porcine Model With 4-Year Follow-Up
      Objectives The aim of the present study was to investigate the relationship between the integration process and luminal enlargement with the support of light intensity (LI) analysis on optical coherence tomography (OCT), echogenicity analysis on intravascular ultrasound, and histology up to 4 years in a porcine model. Background In pre-clinical and clinical studies, late luminal enlargement has been demonstrated at long-term follow-up after everolimus-eluting poly-l-lactic acid coronary scaffold implantation. However ...
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      Mentions: Imperial College London Leiden University Academic Medical Center at the University of Amsterdam

    13. Optical coherence tomography for detection of compound action potential in Xenopus Laevis sciatic nerve

      Explore Conference Proceedings Developmental Biology
      Optical coherence tomography for detection of compound action potential in Xenopus Laevis sciatic nerve
      Due to optical coherence tomography (OCT) high spatial and temporal resolution, this technique could be used to observe the quick changes in the refractive index that accompany action potential. In this study we explore the use of time domain Optical Coherence Tomography (TD-OCT) for real time action potential detection in ex vivo Xenopus Laevis sciatic nerve. TD-OCT is the easiest and less expensive OCT technique and, if successful in detecting ...
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      Mentions: Imperial College London

    14. Edge Vascular Response After Resorption of the Everolimus-Eluting Bioresorbable Vascular Scaffold　– A 5-Year Serial Optical Coherence Tomography Study –

      Explore jstage.jst.go.jp Cardiology
      Edge Vascular Response After Resorption of the Everolimus-Eluting Bioresorbable Vascular Scaffold　– A 5-Year Serial Optical Coherence Tomography Study –
      Background: The edge vascular response (EVR) has been linked to important prognostic implications in patients treated with permanent metallic stents. We aimed to investigate the relationship of EVR with the geometric changes in the everolimus-eluting bioresorbable scaffold using serial optical coherence tomography (OCT) analysis. Methods and Results: In the first-in-man ABSORB trial, 28 patients (29 lesions) underwent serial OCT at 4 different time points (Cohort B1: post-procedure, 6, 24, and ...
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      Mentions: Imperial College London Patrick W. Serruys Yoshinobu Onuma

    16. Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography

      Explore Home - Springer Cardiology
      Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography
      The degree of stent/scaffold embedment could be a surrogate parameter of the vessel wall-stent/scaffold interaction and could have biological implications in the vascular response. We have developed a new specific software for the quantitative evaluation of embedment of struts by optical coherence tomography (OCT). In the present study, we described the algorithm of the embedment analysis and its reproducibility. The degree of embedment was evaluated as the ratio ...
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      Mentions: Imperial College London Leiden University Patrick W. Serruys
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  4. About Imperial College London

    Imperial College London

    Imperial College London is consistently rated amongst the world's best universities, Imperial College London is a science-based institution with a reputation for excellence in teaching and research. Imperial's main campus is located in South Kensington in central London. Formerly a constituent college of the University of London, Imperial became independent of the university on 8 July 2007, the 100th anniversary of its founding.

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