1. Hrebesh M. Subhash

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    1. Mentioned In 45 Articles

    2. High resolution coherence domain depth-resolved nailfold capillaroscopy based on correlation mapping optical coherence tomography

      High resolution coherence domain depth-resolved nailfold capillaroscopy based on correlation mapping optical coherence tomography
      ...ence domain depth-resolved nailfold capillaroscopy based on correlation mapping optical coherence tomography Hrebesh M. Subhash ; Sean O'Gorman ; Kai Neuhaus ; Martin Leahy; High resolution coherence domain depth-resolv...
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    3. Variation in cross-correlation as a discriminator for microvessel imaging using clinical intravascular optical coherence tomography systems

      Variation in cross-correlation as a discriminator for microvessel imaging using clinical intravascular optical coherence tomography systems
      ... imaging using clinical intravascular optical coherence tomography systems Shiju Joseph ; Clément Rousseau ; Hrebesh M. Subhash ; Martin Leahy ; David Adlam; Variation in cross-correlation as a discriminator for microve...
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    4. Nano-sensitive optical coherence tomography (nsOCT) for depth resolved characterization of 3D submicron structure

      Nano-sensitive optical coherence tomography (nsOCT) for depth resolved characterization of 3D submicron structure

      Nowadays optical coherence tomography (OCT) is a rapidly developing technique with various applications, including biomedical imaging and diagnosis. One of the main shortcomings of current OCT techniques is low resolution and sensitivity to structural changes (typically about 10 microns). The best ultra-high resolution OCT techniques demonstrate sensitivity to structural changes and depth resolution of about 1 micron. Since many applications of interest (such as cancer) depend on structural changes at the nanoscale, OCT would definitely benefit from improved structural resolution and sensitivity. A new spectral encoding of spatial frequency (SESF) approach for quantitative characterization of the structure with nanoscale sensitivity ...

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    5. Photothermal optical coherence tomography for depth-resolved imaging of mesenchymal stem cells via single wall carbon nanotube

      Photothermal optical coherence tomography for depth-resolved imaging of mesenchymal stem cells via single wall carbon nanotube
      ...l coherence tomography for depth-resolved imaging of mesenchymal stem cells via single wall carbon nanotubes Hrebesh M. Subhash ; Emma Connolly ; Mary Murphy ; Valerie Barron ; Martin Leahy; Photothermal optical coheren...
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    6. Dermascope assisted interactive patient interface for multiple reference optical coherence tomography

      Dermascope assisted interactive patient interface for multiple reference optical coherence tomography

      There has been a growing interest in the development of a low cost depth-resolved non-invasive dermis imaging tool for both clinical and fundamental investigations of skin diseases. Multiple reference optical coherence tomography (MR-OCT) is a recently developed miniature time-domain low coherence interferometeric imaging platform, which promises to fit into robust, cost-effective designs that are virtually solid state, typical of handheld devices. In this paper we demonstrate the feasibility of MR-OCT for dermis imaging applications by incorporating it in a dermascope, which provides simultaneous imaging of dermis and an interactive tool for beam steering and registration of the OCT imaging beam ...

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    7. Voice coil based robust and miniature optical delay for multiple reference optical coherence tomography

      Voice coil based robust and miniature optical delay for multiple reference optical coherence tomography

      Multiple reference optical coherence tomography (MR-OCT) is a recently developed time-domain interferometeric imaging platform, which promises to fit into robust, cost-effective designs that are virtually solid state. An optical delay is created by the reference mirror which is mounted on a piezo-electric transducer (PZT) and the key element of MR-OCT technology is the presence of a partial mirror in front of the reference mirror. However, the limited axial displacement range at higher scanning-frequencies are a limitation of a PZT-based optical delay. Moreover, PZT-based actuators require a relatively high operational voltage and are expensive. In this paper we present a voice ...

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    8. Imaging mesenchymal stem cells containing single wall nanotube nanoprobes in a 3D scaffold using photo-thermal optical coherence tomography

      Imaging mesenchymal stem cells containing single wall nanotube nanoprobes in a 3D scaffold using photo-thermal optical coherence tomography
      ...e wall nanotube nanoprobes in a 3D scaffold using photo-thermal optical coherence tomography Emma Connolly ; Hrebesh M. Subhash ; Martin J. Leahy ; Niall Rooney ; Frank Barry ; Mary Murphy ; Valerie Barron; Imaging mese...
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    9. Nano-sensitive optical coherence tomography

      Nano-sensitive optical coherence tomography

      Depth resolved label-free detection of structural changes with nanoscale sensitivity is an outstanding problem in the biological and physical sciences and has significant applications in both the fundamental research and healthcare diagnostics arenas. Here we experimentally demonstrate a novel label-free depth resolved sensing technique based on optical coherence tomography (OCT) to detect structural changes at the nanoscale. Structural components of the 3D object, spectrally encoded in the remitted light, are transformed from the Fourier domain into each voxel of the 3D OCT image without compromising sensitivity. Spatial distribution of the nanoscale structural changes in the depth direction is visualized in ...

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    10. Feature Of The Week 1/6/14: In Vivo Full-Field En Face Optical Coherence Tomography

      Feature Of The Week 1/6/14: In Vivo Full-Field En Face Optical Coherence Tomography

      The correlation mapping processing algorithm was developed by our group and utilises the time varying speckle effect produced from moving scatterers to provide contrast against static tissue. The technique has previously been applied to images acquired with frequency-domain OCT systems and hence in a cross-sectional geometry. In this work, a full-field optical coherence tomography system has been developed for the purpose of performing non-scanning en face flow imaging. The light source is centred at 840 nm with a bandwidth of 50 nm resulting in an axial resolution of 8 µm in air. Microscope objectives with a numerical aperture of 0 ...

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    11. Feature Of The Week: High-speed full-range spectral domain correlation mapping optical coherence tomography for in vivo microcirculation imaging applications

      Feature Of The Week: High-speed full-range spectral domain correlation mapping optical coherence tomography for in vivo microcirculation imaging applications

      Microcirculation imaging is a key parameter for studying the pathophysiological processes of various disease conditions, in both clinical and fundamental research. Recently, the functional extension of the OCT technique to image depth-resolved microcirculation has become a very promising area of research. There is a growing interest in the field of development of various types of OCT-based angiographic techniques, which aims to visualize the lumens and architecture of blood vessels in many clinical and fundamental areas of research, including cardiology, dermatology, neurology, ophthalmology, small animal imaging studies, and so forth. OCT-based angiography techniques utilize the red blood cell scattering dynamics as ...

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    12. Microcirculation imaging based on full-range high-speed spectral domain correlation mapping optical coherence tomography

      Microcirculation imaging based on full-range high-speed spectral domain correlation mapping optical coherence tomography

      Microcirculation imaging is a key parameter for studying the pathophysiological processes of various disease conditions, in both clinical and fundamental research. A full-range spectral-domain correlation mapping optical coherence tomography (cm-OCT) method to obtain a complex-conjugate-free, full-range depth-resolved microcirculation map is presented. The proposed system is based on a high-speed spectrometer at 91 kHz with a modified scanning protocol to achieve higher acquisition speed to render cm-OCT images with high-speed and wide scan range. The mirror image elimination is based on linear phase modulation of B-frames by introducing a slight off-set of the probe beam with respect to the lateral scanning ...

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    13. Feature Of The Week 5/19/13: Using Optical Coherence Tomography For Anti-Spoof Fingerprint Detection

      Feature Of The Week 5/19/13: Using Optical Coherence Tomography For Anti-Spoof Fingerprint Detection

      Fingerprint biometrics, including automated fingerprint identification systems (AFIS), currently occupy two-thirds of the biometric market and are expected to remain the dominant player in this area. The technology can be integrated into small, compact devices and the instruments are relatively fast. However, the overall success of using fingerprints for identification and verification purposes greatly depends upon the quality of the fingerprints initially enrolled. For example, fingerprints captured from older people are significantly lower quality than those from younger people due primarily to ridge-wearing and difficulty of interacting effectively with conventional fingerprint scanners. The ramification is that the problem of obtaining ...

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    14. Feasibility of correlation mapping optical coherence tomography (cmOCT) for anti-spoof sub-surface fingerprinting

      Feasibility of correlation mapping optical coherence tomography (cmOCT) for anti-spoof sub-surface fingerprinting

      We propose the use of correlation mapping optical coherence tomography (cmOCT) to deliver additional biometrics associated with the finger that could complement existing fingerprint technology for law enforcement applications. The current study extends the existing fingerprint paradigm by measuring additional biometrics associated with sub-surface finger tissue such as sub-surface fingerprints, sweat glands, and the pattern of the capillary bed to yield a user-friendly cost effective and anti-spoof multi-mode biometric solution associated with the finger. To our knowledge no other method has been able to capture sub-surface fingerprint, papillary pattern and horizontal vessel pattern in a single scan or to show ...

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    15. 1-15 of 45 1 2 3 »
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  2. About Hrebesh M. Subhash

    Hrebesh M. Subhash

    Hrebesh Molly Subhash is with the Biophotonics & Imaging Lab in the School of Medicine at the Oregon Health & Science University. Hrebesh is currently a research associate in Biophotonics and Imaging Laboratory (BAIL), School of Medicine, OHSU Hospital at Portland, OR USA. He works with Prof. R. K. Wang, who is the director of BAIL. His current research activity involves the development of novel optical coherence domain imaging techniques for both anatomical and functional imaging.

    He received his Ph.D. degree in Human Sensing and Functional Sensor Engineering in 2008 from Yamagata University, Yonezawa, Japan. He earned his bachelor's degree in Applied Electronics from the University of Kerala in 1998; his master's in Applied Electronics from the University of Bharathiar in 2000; and his M. Phil in Photonics from the International School of Photonics at the Cochin University of Science and Technology in 2004.

    He was a member of Dr. P.K . Gupta's Biomedical Application Section of RRCAT , Indore. I worked with the Optical Imaging Laboratory led by Dr. Divaker Rao and played a key role in developing the first indigenous Optical Coherence Tomography setup in India.