1. Hrebesh M. Subhash

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    1. Mentioned In 52 Articles

    2. 3D nondestructive testing system with an affordable multiple reference optical-delay-based optical coherence tomography

      3D nondestructive testing system with an affordable multiple reference optical-delay-based optical coherence tomography
      ...ve., Suite 5B, Mountain View, California 94043, USA *Corresponding author: hrebeshms@gmail.com Roshan Dsouza, Hrebesh M. Subhash, Kai Neuhaus, Josh Hogan, Carol Wilson, and Martin Leahy, "3D nondestructive testing system...
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    3. A NANO-SENSITIVE FOURIER-DOMAIN Optical Coherence Tomography Inspection System

      A NANO-SENSITIVE FOURIER-DOMAIN Optical Coherence Tomography Inspection System
      ntroduction The invention relates to inspection of a variety of objects, including body tissue (also in vivo), cell cultures, materials for material science, and micro and nano electronics components, for example. Most of the fundamental pathological processes in living tissues, including cancer, exhibit changes at the nanoscale level. Recently the diffraction resolution limit has been broken and optical nanoscale microscopy has led to creation of nanoscopic medicine. However, nanoscopy largely ...
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    4. Characterization of light distribution and optimization of detector position for multiple reference optical coherence tomography

      Characterization of light distribution and optimization of detector position for multiple reference optical coherence tomography
      A time-domain optical coherence tomography system with respect to multiple reflections in the reference arm is simulated with Zemax and the optimal detector position is discussed based on the wavefront error. Multiple reference optical coherence tomography (MR-OCT) is a novel optical imaging platform using a single miniature actuator and partial mirror to recirculate light multiple times within the interferometric system. The recirculation corresponds to multiple path delays extending effectively the ...
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    5. Signal simulation and signal processing for multiple reference optical coherence tomography

      Signal simulation and signal processing for multiple reference optical coherence tomography
      The generation of a synthetic MR-OCT signal is presented and compared to a real acquired signal. Multiple reference optical coherence tomography (MR-OCT) is a novel time-domain interferometric system. The MR-OCT principle is adding a partial mirror to extend the axial scan range, which effectively extends the scan depth for imaging. The actuation of the scan mirror required for time-domain OCT, was demonstrated to operate with a low cost miniature voice ...
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    6. Developing cross-correlation as a method for microvessel imaging using clinical intravascular optical coherence tomography systems

      Developing cross-correlation as a method for microvessel imaging using clinical intravascular optical coherence tomography systems
      Current clinical intravascular optical coherence tomography (IV-OCT) imaging systems have limited in-vivo flow imaging capability because of non-uniform catheter rotation and inadequate A-line scan density. Thus any flow-localisation method that seeks to identify sites of variation within the OCT image data-sets, whether that is in amplitude or phase, produces non-representative correlation (or variance) maps. In this study, both mean and the variation within a set of cross-correlation maps, for static ...
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    7. High resolution coherence domain depth-resolved nailfold capillaroscopy based on correlation mapping optical coherence tomography

      High resolution coherence domain depth-resolved nailfold capillaroscopy based on correlation mapping optical coherence tomography
      ...ence domain depth-resolved nailfold capillaroscopy based on correlation mapping optical coherence tomography Hrebesh M. Subhash ; Sean O'Gorman ; Kai Neuhaus ; Martin Leahy; High resolution coherence domain depth-resolv...
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    8. Variation in cross-correlation as a discriminator for microvessel imaging using clinical intravascular optical coherence tomography systems

      Variation in cross-correlation as a discriminator for microvessel imaging using clinical intravascular optical coherence tomography systems
      ... imaging using clinical intravascular optical coherence tomography systems Shiju Joseph ; Clément Rousseau ; Hrebesh M. Subhash ; Martin Leahy ; David Adlam; Variation in cross-correlation as a discriminator for microve...
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    9. Nano-sensitive optical coherence tomography (nsOCT) for depth resolved characterization of 3D submicron structure

      Nano-sensitive optical coherence tomography (nsOCT) for depth resolved characterization of 3D submicron structure
      Nowadays optical coherence tomography (OCT) is a rapidly developing technique with various applications, including biomedical imaging and diagnosis. One of the main shortcomings of current OCT techniques is low resolution and sensitivity to structural changes (typically about 10 microns). The best ultra-high resolution OCT techniques demonstrate sensitivity to structural changes and depth resolution of about 1 micron. Since many applications of interest (such as cancer) depend on structural changes at ...
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    10. Photothermal optical coherence tomography for depth-resolved imaging of mesenchymal stem cells via single wall carbon nanotube

      Photothermal optical coherence tomography for depth-resolved imaging of mesenchymal stem cells via single wall carbon nanotube
      ...l coherence tomography for depth-resolved imaging of mesenchymal stem cells via single wall carbon nanotubes Hrebesh M. Subhash ; Emma Connolly ; Mary Murphy ; Valerie Barron ; Martin Leahy; Photothermal optical coheren...
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    11. Dermascope assisted interactive patient interface for multiple reference optical coherence tomography

      Dermascope assisted interactive patient interface for multiple reference optical coherence tomography
      There has been a growing interest in the development of a low cost depth-resolved non-invasive dermis imaging tool for both clinical and fundamental investigations of skin diseases. Multiple reference optical coherence tomography (MR-OCT) is a recently developed miniature time-domain low coherence interferometeric imaging platform, which promises to fit into robust, cost-effective designs that are virtually solid state, typical of handheld devices. In this paper we demonstrate the feasibility of MR-OCT ...
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    12. Voice coil based robust and miniature optical delay for multiple reference optical coherence tomography

      Voice coil based robust and miniature optical delay for multiple reference optical coherence tomography
      Multiple reference optical coherence tomography (MR-OCT) is a recently developed time-domain interferometeric imaging platform, which promises to fit into robust, cost-effective designs that are virtually solid state. An optical delay is created by the reference mirror which is mounted on a piezo-electric transducer (PZT) and the key element of MR-OCT technology is the presence of a partial mirror in front of the reference mirror. However, the limited axial displacement range ...
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    13. Imaging mesenchymal stem cells containing single wall nanotube nanoprobes in a 3D scaffold using photo-thermal optical coherence tomography

      Imaging mesenchymal stem cells containing single wall nanotube nanoprobes in a 3D scaffold using photo-thermal optical coherence tomography
      ...e wall nanotube nanoprobes in a 3D scaffold using photo-thermal optical coherence tomography Emma Connolly ; Hrebesh M. Subhash ; Martin J. Leahy ; Niall Rooney ; Frank Barry ; Mary Murphy ; Valerie Barron; Imaging mese...
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  2. About Hrebesh M. Subhash

    Hrebesh M. Subhash

    Hrebesh Molly Subhash is with the Biophotonics & Imaging Lab in the School of Medicine at the Oregon Health & Science University. Hrebesh is currently a research associate in Biophotonics and Imaging Laboratory (BAIL), School of Medicine, OHSU Hospital at Portland, OR USA. He works with Prof. R. K. Wang, who is the director of BAIL. His current research activity involves the development of novel optical coherence domain imaging techniques for both anatomical and functional imaging.

    He received his Ph.D. degree in Human Sensing and Functional Sensor Engineering in 2008 from Yamagata University, Yonezawa, Japan. He earned his bachelor's degree in Applied Electronics from the University of Kerala in 1998; his master's in Applied Electronics from the University of Bharathiar in 2000; and his M. Phil in Photonics from the International School of Photonics at the Cochin University of Science and Technology in 2004.

    He was a member of Dr. P.K . Gupta's Biomedical Application Section of RRCAT , Indore. I worked with the Optical Imaging Laboratory led by Dr. Divaker Rao and played a key role in developing the first indigenous Optical Coherence Tomography setup in India.