1. Hiroshi Mashimo

    0 Comments Leave a Comment

    1-15 of 28 1 2 »

    1. Mentioned In 28 Articles

    2. Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography

      Explore SPIE | Journal Gastroenterology
      Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography
      Radiofrequency ablation (RFA) is widely used for the eradication of dysplasia and the treatment of early stage esophageal carcinoma in patients with Barretts esophagus (BE). However, there are several factors, such as variation of BE epithelium (EP) thickness among individual patients and varying RFA catheter-tissue contact, which may compromise RFA efficacy. We used a high-speed optical coherence tomography (OCT) system to identify and monitor changes in the esophageal tissue architecture ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Harvard University

    3. Endoscopic optical coherence tomography angiography microvascular features associated with dysplasia in Barrett's esophagus: a pilot study (with video)

      Explore Elsevier Health Gastroenterology , Oncology
      Endoscopic optical coherence tomography angiography microvascular features associated with dysplasia in Barrett's esophagus: a pilot study (with video)
      Background and Aims Angiogenesis is associated with neoplastic progression of Barretts esophagus (BE). Volumetric optical coherence tomography angiography (OCTA) visualizes subsurface microvasculature without exogenous contrast agents. We investigated the association of OCTA microvascular features with low-grade dysplasia (LGD) and high-grade dysplasia (HGD). Methods Fifty-two patients undergoing BE surveillance or endoscopic eradication therapies for dysplasia were imaged using volumetric OCTA and corresponding histological diagnoses obtained, to yield 97 data sets (non-dysplastic ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    4. Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography

      Explore OSA | OSA Publishing Gastroenterology
      Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography
      Early detection of neoplastic changes remains a critical challenge in clinical cancer diagnosis and treatment. Many cancers arise from epithelial layers such as those of the gastrointestinal (GI) tract. Current standard endoscopic technology is difficult to detect the subsurface lesions. In this research, we investigated the feasibility of a novel multi-modal optical imaging approach including high-resolution optical coherence tomography (OCT) and high-sensitivity fluorescence laminar optical tomography (FLOT) for structural and ...
      Read Full Article
      Mentions: University of Maryland University of Rochester Harvard University

    5. Volumetric Mapping of Barrett’s Esophagus and Dysplasia With en face Optical Coherence Tomography Tethered Capsule

      Explore Nature Publishing Group Gastroenterology
      Volumetric Mapping of Barrett’s Esophagus and Dysplasia With en face Optical Coherence Tomography Tethered Capsule
      To the Editor: Dysplasia in Barretts Esophagus (BE) is patchy ( 1 ) and sometimes missed by random biopsies. Optical coherence tomography (OCT) can image large areas of the esophagus; however, slow imaging speeds in earlier studies limited visualization to cross-sections. Cross-sectional OCT detected high-grade dysplasia with sensitivity / specificity of ~80 % ( 2 , 3 ). Tethered OCT capsules were demonstrated for cross-sectional imaging in unsedated screening to detect BE ( 4 , 5 ). Our group recently ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    6. Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter
      We demonstrate a micromotor balloon imaging catheter for ultrahigh speed endoscopic optical coherence tomography (OCT) which provides wide area, circumferential structural and angiographic imaging of the esophagus without contrast agents. Using a 1310 nm MEMS tunable wavelength swept VCSEL light source, the system has a 1.2 MHz A-scan rate and ~8.5 m axial resolution in tissue. The micromotor balloon catheter enables circumferential imaging of the esophagus at 240 ...
      Read Full Article
      Mentions: Brigham and Women’s Hospital Massachusetts Institute of Technology James G. Fujimoto

    7. Feature Of The Week 03/08/2015: Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature

      Explore Optical Coherence Tomography News Gastroenterology
      Feature Of The Week 03/08/2015: Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature
      Endoscopic imaging technologies such as confocal laser endomicroscopy (CLE) and narrowband imaging (NBI) have been used to investigate vascular changes as hallmarks of early cancer in the GI tract. However, the limited frame rate and field of view make CLE imaging sensitive to motion artifacts, whereas NBI has limited resolution and visualizes only the surface vascular pattern. Endoscopic optical coherence tomography (OCT) enables high speed volumetric imaging of subsurface features ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    8. Ultrahigh speed en face OCT capsule for endoscopic imaging

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Ultrahigh speed en face OCT capsule for endoscopic imaging
      Depth resolved anden faceOCT visualizationin vivomay have important clinical applications in endoscopy. We demonstrate a high speed, two-dimensional (2D) distal scanning capsule with a micromotor for fast rotary scanning and a pneumatic actuator for precision longitudinal scanning. Longitudinal position measurement and image registration were performed by optical tracking of the pneumatic scanner. The 2D scanning device enables high resolution imaging over a small field of view and is suitable for ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    9. Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature

      Explore Gastroenterology Gastroenterology
      Endoscopic Optical Coherence Angiography Enables Three Dimensional Visualization of Subsurface Microvasculature
      Endoscopic imaging technologies such as confocal laser endomicroscopy1and narrow band imaging (NBI)2have been used to investigate vascular changes as hallmarks of early cancer in the gastrointestinal tract. However, the limited frame rate and field of view make confocal laser endomicroscopy imaging sensitive to motion artifacts, whereas NBI has limited resolution and visualizes only the surface vascular pattern. Endoscopic optical coherence tomography (OCT) enables high-speed volumetric imaging of subsurface features ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    10. Ultrahigh speed endoscopic optical coherence tomography for gastroenterology

      Explore opticsinfobase.org Gastroenterology
      Ultrahigh speed endoscopic optical coherence tomography for gastroenterology
      We describe an ultrahigh speed endoscopic swept source optical coherence tomography (OCT) system for clinical gastroenterology using a vertical-cavity surface-emitting laser (VCSEL) and micromotor imaging catheter. The system had a 600 kHz axial scan rate and 8 m axial resolution in tissue. Imaging was performed with a 3.2 mm diameter imaging catheter at 400 frames per second with a 12 m spot size. Three-dimensional OCT (3D-OCT) imaging was performed ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    13. Endoscopic Optical Coherence Angiography Enables 3-Dimensional Visualization of Subsurface Microvasculature

      Explore Gastroenterology Gastroenterology
      Endoscopic Optical Coherence Angiography Enables 3-Dimensional Visualization of Subsurface Microvasculature
      Endoscopic imaging technologies such as confocal laser endomicroscopy 1 and narrow band imaging (NBI) 2 have been used to investigate vascular changes as hallmarks of early cancer in the gastrointestinal tract. However, the limited frame rate and field of view make confocal laser endomicroscopy imaging sensitive to motion artifacts, whereas NBI has limited resolution and visualizes only the surface vascular pattern. Endoscopic optical coherence tomography (OCT) enables high-speed volumetric imaging ...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    15. Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light source and micromotor catheter

      Explore Conference Proceedings Gastroenterology
      Ultrahigh speed endoscopic swept source optical coherence tomography using a VCSEL light source and micromotor catheter
      ...uankai K. Tao ; Vijaysekhar Jayaraman ; Martin F. Kraus ; Joachim Hornegger ; Marisa Figueiredo ; Qin Huang ; Hiroshi Mashimo ; Alex E. Cable ; James G. Fujimoto; Ultrahigh speed endoscopic swept source optical coherence...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    16. Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology

      Explore opticsinfobase.org Cardiology , Gastroenterology , Probes
      Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology
      ...ekhar Jayaraman,^3 James Jiang,^2 Peter J. S. Heim,^4 Martin F. Kraus,^1,^5 Chao Zhou,^1 Joachim Hornegger,^5 Hiroshi Mashimo,^6 Alex E. Cable,^2 and James G. Fujimoto^1,^* ^1Department of Electrical Engineering and Co...
      Read Full Article
      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs
    17. 1-15 of 28 1 2 »
  1. Search:

  2. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology

    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents

    3. Technology:

      Broadband Sources, Probes, Tunable Sources

    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks

  4. About Hiroshi Mashimo

    Hiroshi Mashimo

    Hiroshi Mashimo is a principal investigator and faculty member at Harvard Medical School and Boston VA Healthcare System.

  5. Related Topics

    1. Effects of axial resolution improvement on optical coherence tomography (OCT) imaging of gastrointestinal tissues
      28 articles also mentioned James G. Fujimoto
    2. Three-dimensional endomicroscopy of the human colon using optical coherence tomography
      22 articles also mentioned Tsung-Han Tsai
    3. Features of Sub-Epithelial Glandular Structures on Three-Dimensional Endoscopic Optical Coherence Tomography (3D-EOCT) After Endoscopic Mucosal Ablation
      20 articles also mentioned Hsiang-Chieh Lee
    4. Cellular resolution ex vivo imaging of gastrointestinal tissues with optical coherence microscopy
      16 articles also mentioned Harvard University
    5. Buried (but not dead) Barrett's metaplasia: tales from the crypts
      13 articles also mentioned Osman O. Ahsen