1. Hiroshi Goto

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    1-14 of 14
    1. Mentioned In 14 Articles

    2. Evaluation of Retinal Pigment Epithelium Layer Change in Vogt-Koyanagi-Harada Disease With Multicontrast Optical Coherence Tomography

      Evaluation of Retinal Pigment Epithelium Layer Change in Vogt-Koyanagi-Harada Disease With Multicontrast Optical Coherence Tomography
      Purpose : Clinical evaluation of retinal pigment epithelium (RPE) change is important for the therapeutic management of chronic Vogt-Koyanagi-Harada (VKH) disease. We evaluated long-term change in the RPE layer in VKH disease, using near-infrared (NIR; 817 nm) images and autofluorescence images at 488 nm (short-wavelength [SW]-AF) and 785 nm (NIR-AF), and compared those images with images from multicontrast optical coherence tomography (MC-OCT). MC-OCT is capable of simultaneous measurement of OCT ...
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    3. Objective evaluation of choroidal melanin contents with polarization-sensitive optical coherence tomography

      Objective evaluation of choroidal melanin contents with polarization-sensitive optical coherence tomography
      We non-invasively evaluated choroidal melanin contents in human eyes with PS-OCT. We calculated the percentage area of low DOPU in the choroidal interstitial stroma for Vogt-Koyanagi- Harada disease with sunset glow fundus, without sunset glow fundus, control group and tessellated fundus with high myopia. The mean percentage area of low DOPU in the sunset group was significantly lower than the other groups. PS-OCT provides an in vivo objective evaluation of ...
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    4. Evaluation of intraretinal migration of retinal pigment epithelial cells with Jones matrix optical coherence tomography

      Evaluation of intraretinal migration of retinal pigment epithelial cells with Jones matrix optical coherence tomography
      We evaluated intraretinal RPE migration in AMD using multimodal imaging including polarimetric images. Depolarized light images were computed using a PS-SLO. M-DOPU was calculated using multifunctional Jones-matrix OCT. RPE migration was detected in 59 of 155 eyes. Focal similarities could be confirmed among en-face projection images of minimum M-DOPU, depolarized light images, and NIR-AF images.
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    5. Noninvasive vascular imaging of ruptured retinal arterial macroaneurysms by Doppler optical coherence tomography

      Noninvasive vascular imaging of ruptured retinal arterial macroaneurysms by Doppler optical coherence tomography
      Background To describe Doppler optical coherence tomography (OCT) imaging of ruptured retinal arterial macroaneurysms (RAMs). Methods Four eyes of four patients with ruptured RAMs were prospectively studied. Vascular imaging was obtained using swept-source Doppler OCT, and compared with indocyanine green angiography images. Results En face projection of Doppler OCT images clearly showed RAMs at the corresponding locations of lesions in the indocyanine green angiography images. In Doppler OCT images, RAMs ...
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    6. Noninvasive Vascular Imaging of Polypoidal Choroidal Vasculopathy by Doppler Optical Coherence Tomography

      Noninvasive Vascular Imaging of Polypoidal Choroidal Vasculopathy by Doppler Optical Coherence Tomography
      Purpose. To noninvasively investigate the vascular architecture of polypoidal lesions in polypoidal choroidal vasculopathy (PCV) using Doppler optical coherence tomography (OCT), and to evaluate the clinical usefulness of Doppler OCT for the assessment of therapeutic effects in PCV. Methods. Fifteen eyes of 15 patients with treatment-nave PCV were prospectively studied. Vascular imaging was obtained using 1060-nm swept-source Doppler OCT, and compared with indocyanine green angiography (ICGA) images. The therapeutic effect ...
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    7. Three-Dimensional Vascular Imaging of Proliferative Diabetic Retinopathy by Doppler Optical Coherence Tomography

      Three-Dimensional Vascular Imaging of Proliferative Diabetic Retinopathy by Doppler Optical Coherence Tomography
      Purpose To evaluate the three-dimensional architecture of neovascularization in proliferative diabetic retinopathy using Doppler optical coherence tomography (OCT). Design Prospective, nonrandomized clinical trial. Methods Seventeen eyes of 14 patients with proliferative diabetic retinopathy were prospectively studied. Prototype Doppler OCT was used to evaluate the three-dimensional vascular architecture at vitreoretinal adhesions. Results Proliferative membranes were detected in all eyes with proliferative diabetic retinopathy by standard OCT images. Doppler OCT images detected ...
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    8. Depiction of Cavity Formation in Terrien Marginal Degeneration by Anterior Segment Optical Coherence Tomography

      Depiction of Cavity Formation in Terrien Marginal Degeneration by Anterior Segment Optical Coherence Tomography
      Purpose: To evaluate detailed morphologic changes of Terrien marginal degeneration (TMD) using anterior segment optical coherence tomography (AS-OCT). Methods: Two patients with TMD were examined by 1310-nm wavelength swept source optical coherence tomography, corneal topography, and slit-lamp microscopy. Results: AS-OCT depicted corneal thinning with intact epithelial layer in the peripheral cornea of both patients. Moreover, AS-OCT images of both patients clearly showed cavity formation surrounded and enclosed by intact epithelial ...
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    9. Biological activity is the likely origin of the intersection between the photoreceptor inner and outer segments of the rat retina as determined by optical coherence tomography

      Biological activity is the likely origin of the intersection between the photoreceptor inner and outer segments of the rat retina as determined by optical coherence tomography
      ...amauchi, Hiromichi Yagi, Yoshihiko Usui, Keisuke Kimura, Tsuyoshi Agawa, Rintaro Tsukahara, Naoyuki Yamakawa, Hiroshi Goto Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan Background: Recent r...
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    10. Correlation between high-resolution optical coherence tomography (OCT) images and histopathology in an N-methyl-N-nitrosourea–induced retinal degeneration rat model

      Correlation between high-resolution optical coherence tomography (OCT) images and histopathology in an N-methyl-N-nitrosourea–induced retinal degeneration rat model
      ...amauchi, 2. Keisuke Kimura, 3. Tsuyoshi Agawa, 4. Rintaro Tsukahara, 5. Maki Mishima, 6. Naoyuki Yamakawa, 7. Hiroshi Goto 1. Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan 1. Correspondence...
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    11. Correlation between high-resolution optical coherence tomography (OCT) images and histopathology in an iodoacetic acid-induced model of retinal degeneration in rabbits

      Correlation between high-resolution optical coherence tomography (OCT) images and histopathology in an iodoacetic acid-induced model of retinal degeneration in rabbits
      Background Recent research on macular disease has prompted investigation into the condition of the intersection of the inner and outer segments (IS/OS) and its relationship with retinal photoreceptor abnormalities. Because the relationship between optical coherence tomography (OCT) images and histopathology is unclear, we compared these in an iodoacetic acid (IAA)-induced model of photoreceptor degeneration in rabbits. Methods IAA (20 mg/kg), which is toxic to photoreceptors, was injected ...
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    12. Three-Dimensional Optical Coherence Tomography-Guided Phototherapeutic Keratectomy for Granular Corneal Dystrophy

      Purpose: To describe the potential use of three-dimensional optical coherence tomography (OCT)-guided phototherapeutic keratectomy (PTK) for granular corneal dystrophy. Design: Investigative case report. Methods: Three-dimensional volume data of 1310-nm high-speed swept-source OCT was used to simulate the effect of PTK performed for the removal of corneal opacity in a patient with granular corneal dystrophy. Results: The OCT projection view was used to visualize the reduction of the area of ...
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  2. About Hiroshi Goto

    Hiroshi Goto is from the Department of Ophthalmology at the Tokyo Medical University Hospital in Japan.