1. Hendrik P. N. Scholl

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    1. Mentioned In 17 Articles

    2. Novel biomarker of sphericity and cylindricity indices in volume-rendering optical coherence tomography angiography in normal and diabetic eyes: a preliminary study

      Explore Home - Springer Ophthalmology
      Novel biomarker of sphericity and cylindricity indices in volume-rendering optical coherence tomography angiography in normal and diabetic eyes: a preliminary study
      Purpose Preliminary to evaluate geometric indices (vessel sphericity and cylindricity) for volume-rendered optical coherence tomography angiography (OCTA) in healthy and diabetic eyes. Methods Twenty-six eyes of 13 healthy subjects and 12 eyes of patients with central ischemic, non-proliferative diabetic retinopathy were included. OCTA volume and surface area of the foveal vessels were measured and compared to determine OCTA sphericity and cylindricity indices and surface efficiency (SE). Results The overall average ...
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      Mentions: University of Bonn Richard F. Spaide Hendrik P. N. Scholl

    3. Validation of automated artificial intelligence segmentation of optical coherence tomography images

      Explore Journals | PLOS Ophthalmology
      Validation of automated artificial intelligence segmentation of optical coherence tomography images
      Purpose To benchmark the human and machine performance of spectral-domain (SD) and swept-source (SS) optical coherence tomography (OCT) image segmentation, i.e., pixel-wise classification, for the compartments vitreous, retina, choroid, sclera. Methods A convolutional neural network (CNN) was trained on OCT B-scan images annotated by a senior ground truth expert retina specialist to segment the posterior eye compartments. Independent benchmark data sets (30 SDOCT and 30 SSOCT) were manually segmented ...
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      Mentions: University of Bonn Hendrik P. N. Scholl Adnan Tufail

    4. Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease

      Explore Home - Springer Ophthalmology
      Impact of segmentation density on spectral domain optical coherence tomography assessment in Stargardt disease
      Purpose Automated spectral domain optical coherence tomography (SD-OCT) segmentation algorithms currently do not perform well in segmenting individual intraretinal layers in eyes with Stargardt disease (STGD). We compared selective B-scan segmentation strategies for generating mean retinal layer thickness and preserved area data from SD-OCT scans in patients with STGD1. Methods Forty-five eyes from 40 Stargardt patients were randomly selected from the ongoing Natural History of the Progression of Atrophy Secondary ...
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      Mentions: Johns Hopkins University University College London Hendrik P. N. Scholl

    5. Safety and Feasibility of a Novel Sparse Optical Coherence Tomography Device for Patient-Delivered Retina Home Monitoring

      Explore TVST Journal Ophthalmology
      Safety and Feasibility of a Novel Sparse Optical Coherence Tomography Device for Patient-Delivered Retina Home Monitoring
      Purpose : To study a novel and fast optical coherence tomography (OCT) device for home-based monitoring in age-related macular degeneration (AMD) in a small sample yielding sparse OCT (spOCT) data and to compare the device to a commercially available reference device. Methods : In this prospective study, both eyes of 31 participants with AMD were included. The subjects underwent scanning with an OCT prototype and a spectral-domain OCT to compare the accuracy ...
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      Mentions: University Hospital Zurich Hendrik P. N. Scholl Adnan Tufail

    6. High-Performance Virtual Reality Volume Rendering of Original Optical Coherence Tomography Point-Cloud Data Enhanced With Real-Time Ray Casting

      Explore TVST Journal Ophthalmology
      High-Performance Virtual Reality Volume Rendering of Original Optical Coherence Tomography Point-Cloud Data Enhanced With Real-Time Ray Casting
      Purpose : Feasibility testing of a novel volume renders technology to display optical coherence tomography data (OCT) in a virtual reality (VR) environment. Methods : A VR program was written in C++/OpenGL to import and display volumetric OCT data in real time with 180 frames per second using a high-end computer and a tethered head-mounted display. Following exposure, participants completed a Simulator Sickness Questionnaire (SSQ) to assess for nausea, disorientation, and ...
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      Mentions: Hendrik P. N. Scholl Adnan Tufail

    8. THREE-DIMENSIONAL ANALYSIS OF SUBMACULAR PERFORATING SCLERAL VESSELS BY ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY

      Explore LWW Online Ophthalmology
      THREE-DIMENSIONAL ANALYSIS OF SUBMACULAR PERFORATING SCLERAL VESSELS BY ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To analyze submacular perforating scleral vessels (PSVs) using enhanced depth imaging spectral domain optical coherence tomography (EDI-SDOCT). Methods: Twenty-two eyes of 11 healthy women were included in this retrospective study. Central EDI-SDOCT scans (3 x 4.5 x 1.9 mm, 13.5 mm2 scan area) were acquired and postprocessed by denoising, manual sclera segmentation, and PSV investigated by five graders. Results: Mean age was 22.4 +/- 6.2 ...
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      Mentions: Johns Hopkins University University Hospital Zurich Hendrik P. N. Scholl

    9. Assessment of estimated retinal atrophy progression in Stargardt macular dystrophy using spectral-domain optical coherence tomography

      Explore BJO Online Ophthalmology
      Assessment of estimated retinal atrophy progression in Stargardt macular dystrophy using spectral-domain optical coherence tomography
      Aims To estimate disease progression based on analysis of macular volume measured by spectral-domain optical coherence tomography (SD-OCT) in patients affected by Stargardt macular dystrophy (STGD1) and to evaluate the influence of software errors on these measurements. Methods 58 eyes of 29 STGD1 patients were included. Numbers and types of algorithm errors were recorded and manually corrected. In a subgroup of 36 eyes of 18 patients with at least two ...
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      Mentions: Johns Hopkins University University of Graz Hendrik P. N. Scholl

    10. An integrated software solution for multi-modal mapping of morphological and functional ocular data

      Explore IEEE Xplore Ophthalmology
      An integrated software solution for multi-modal mapping of morphological and functional ocular data
      Various morphological and functional techniques for retina examination have been established in the recent years. Although many examination results are spatially resolved and can be mapped onto data originating from other modalities, usually only data from one modality is analyzed by a clinician at a time. This is mainly because there is no software available to the public that enables the registration of structure and function in the clinical setting ...
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      Mentions: University of Tübingen Hendrik P. N. Scholl Peter Charbel Issa

    12. Spectral Domain Optical Coherence Tomography in Adult-Onset Vitelliform Macular Dystrophy With Cuticular Drusen

      Explore LWW Online Ophthalmology
      Spectral Domain Optical Coherence Tomography in Adult-Onset Vitelliform Macular Dystrophy With Cuticular Drusen
      Purpose: The purpose of this study was to investigate morphologic differences in a consecutive case series of patients suffering from adult-onset vitelliform macular dystrophy with cuticular drusen (CD) compared with another patient group with a vitelliform lesion only using high-resolution in vivo retinal imaging. Methods: Simultaneous spectral domain optical coherence tomography (870 nm, 40.000 A-scans per second) and confocal scanning laser ophthalmoscopy were performed in 6 patients (12 eyes ...
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      Mentions: Heidelberg Engineering University of Bonn Frank G. Holz

    13. Outer Retinal Hyperreflective Spots on Spectral-Domain Optical Coherence Tomography in Macular Telangiectasia Type 2

      Explore OphSource Ophthalmology
      Outer Retinal Hyperreflective Spots on Spectral-Domain Optical Coherence Tomography in Macular Telangiectasia Type 2
      Purpose: To analyze focal hyperreflective morphologic alterations in outer retinal layers in patients with type 2 idiopathic macular telangiectasia (MacTel type 2) using spectral-domain optical coherence tomography (SD OCT).Design: Cross-sectional case-control study.Participants: Forty-one patients with MacTel type 2.Methods: Anatomic layers were evaluated and compared with those of controls of similar age. Simultaneous SD OCT scans were obtained with a combined confocal scanning laser ophthalmoscope for simultaneous tomographic ...
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      Mentions: Université Pierre et Marie Curie Johns Hopkins University Heidelberg Engineering

    14. Clinical evaluation of simultaneous confocal scanning laser ophthalmoscopy imaging combined with high-resolution, spectral-domain optical coherence tomography

      Explore www3.interscience.wiley.com Microscopy , Ophthalmology
      Purpose: To evaluate the clinical relevance of a new diagnostic modality, simultaneous confocal scanning laser ophthalmoscopy (cSLO) and high-speed, high-resolution, spectral-domain optical coherence tomography (OCT), for the visualization of macular pathologies. Methods: OCT images and simultaneous recording of fluorescein angiography, indocyanine green (ICG) angiography, infrared, and blue reflectance ('red-free') or fundus autofluorecence (FAF) images were obtained with a novel imaging device (Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany). An optically ...
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      Mentions: Heidelberg Engineering University of Bonn Frank G. Holz

    15. Multimodal imaging including spectral domain OCT and confocal near infrared reflectance for characterisation of outer retinal pathology in pseudoxanthoma elasticum

      Explore iovs.org Ophthalmology
      ...inal pathology in pseudoxanthoma elasticum Peter Charbel Issa ^1^*, Robert P Finger ^2, Frank G. Holz ^2, and Hendrik P. N. Scholl ^2 ^^1 Department of Ophthalmology, University of Bonn, Ernst-Abbe-Str. 2, Bonn, 53127, G...
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      Mentions: University of Bonn Frank G. Holz Hendrik P. N. Scholl

    16. Multimodal Fundus Imaging in Foveal Hypoplasia: Combined Scanning Laser Ophthalmoscope Imaging and Spectral-Domain Optical Coherence Tomography

      Explore Archives of Ophthalmology Ophthalmology
      ...Spectral-Domain Optical Coherence Tomography Peter Charbel Issa, MD; Michael Foerl, MD; Hans-Martin Helb, MD; Hendrik P. N. Scholl, MD, MA; Frank G. Holz, MD Arch Ophthalmol. 2008;126(10):1463-1465. Foveal hypoplasia is ...
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      Mentions: Heidelberg Engineering University of Bonn Frank G. Holz

    17. Correlation of Lines of Increased Autofluorescence in Macular Dystrophy and Pigmented Paravenous Retinochoroidal Atrophy by Optical Coherence Tomography

      Explore Archives of Ophthalmology Ophthalmology
      ...raphy Monika Fleckenstein, MD; Peter Charbel Issa, MD; Hans-Martin Helb, MD; Steffen Schmitz-Valckenberg, MD; Hendrik P. N. Scholl, MD; Frank G. Holz, MD Arch Ophthalmol. 2008;126(10):1461-1463. Discrete lines of increas...
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      Mentions: Heidelberg Engineering University of Bonn Frank G. Holz

    18. High resolution Spectral Domain-OCT imaging in Geographic Atrophy associated with Age-related Macular Degeneration.

      Explore NCBI HomePage Ophthalmology
      Purpose: To describe morphological variations in outer retinal layers in eyes with atrophic age-related macular degeneration (AMD) using high-resolution, spectral-domain optical coherence tomography (SD-OCT). Methods: SD-OCT scans were obtained with a combined confocal scanning laser ophthalmoscope (cSLO) and SD-OCT for simultaneous tomographic and topographic in vivo imaging. A total of 81 eyes of 56 patients (mean age 77.8 +/- 7.4) with geographic atrophy (GA) were examined. Morphological alterations were ...
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      Mentions: University of Bonn Frank G. Holz Hendrik P. N. Scholl
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  4. About Hendrik P. N. Scholl

    Hendrik P. N. Scholl

    Hendrik P. N. Scholl, MD, is in the Department of Ophthalmology, University of Bonn, Germany.

  5. Related Topics

    1. High resolution Spectral Domain-OCT imaging in Geographic Atrophy associated with Age-related Macular Degeneration.
      11 articles also mentioned University of Bonn
    2. Correlation of Lines of Increased Autofluorescence in Macular Dystrophy and Pigmented Paravenous Retinochoroidal Atrophy by Optical Coherence Tomography
      6 articles also mentioned Heidelberg Spectralis
    3. THREE-DIMENSIONAL ANALYSIS OF SUBMACULAR PERFORATING SCLERAL VESSELS BY ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY
      6 articles also mentioned Adnan Tufail
    4. Outer Retinal Hyperreflective Spots on Spectral-Domain Optical Coherence Tomography in Macular Telangiectasia Type 2
      5 articles also mentioned Johns Hopkins University