1. Heinrich-Heine University Düsseldorf

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    1. Mentioned In 11 Articles

    2. No alteration of optical coherence tomography and multifocal visual evoked potentials in eyes with symptomatic carotid artery disease

      No alteration of optical coherence tomography and multifocal visual evoked potentials in eyes with symptomatic carotid artery disease
      Background Symptomatic carotid artery disease (CAD) may cause modified blood supply to the retina possibly leading to retinal structure changes. Results of previous studies in asymptomatic CAD were heterogeneous in retinal layer changes measured by OCT. The objectives of this prospective, non-interventional study were to investigate if structural retinal changes occur in symptomatic CAD patients with macroangiopathic ischemic stroke or transient ischemic attack (TIA). Methods We used spectral-domain optical coherence ...
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    3. The APOSTEL recommendations for reporting quantitative optical coherence tomography studies

      The APOSTEL recommendations for reporting quantitative optical coherence tomography studies
      Objective: To develop consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results. Methods: A panel of experienced OCT researchers (including 11 neurologists, 2 ophthalmologists, and 2 neuroscientists) discussed requirements for performing and reporting quantitative analyses of retinal morphology and developed a list of initial recommendations based on experience and previous studies. The list of recommendations was subsequently revised during several meetings of the coordinating group. Results: We ...
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    4. Timing of retinal neuronal and axonal loss in MS: a longitudinal OCT study

      Timing of retinal neuronal and axonal loss in MS: a longitudinal OCT study
      The objective of the study was to investigate the timing of central nervous system tissue atrophy in MS by evaluating longitudinal retinal volume changes in a broadly representative cohort with disease duration across the entire arc of disease. In this longitudinal study, 135 patients with MS and 16 healthy reference subjects underwent spectral-domain optical coherence tomography (OCT) at baseline and 2 years later. Following OCT quality control, automated segmentation of ...
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    5. Retinal pathology in Susac syndrome detected by spectral-domain optical coherence tomography

      Retinal pathology in Susac syndrome detected by spectral-domain optical coherence tomography
      Objective: The aim of this non-interventional study was to characterize retinal layer pathology in Susac syndrome (SuS), a disease with presumably autoimmune-mediated microvessel occlusions in the retina, brain, and inner ear, in comparison to the most important differential diagnosis multiple sclerosis (MS). Methods: Seventeen patients with SuS and 17 age- and sex-matched patients with relapsing-remitting MS (RRMS) and healthy controls (HC) were prospectively investigated by spectral-domain optical coherence tomography (OCT ...
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    6. Update on Susac Syndrome: New Insights in Brain and Retinal Imaging and Treatment Options

      Update on Susac Syndrome: New Insights in Brain and Retinal Imaging and Treatment Options
      Susac syndrome (SuS) is a rare endotheliopathy of the brain, the retina, and the inner ear. The underlying pathophysiology is likely an autoimmune mediated occlusion of microvessels resulting in variable degrees of central nervous system (CNS) dysfunction, visual disturbances, and hearing loss. The disease manifests either with a monophasic or polycyclic course. Patients suffering from SuS are frequently misdiagnosed as having inflammatory demyelinating CNS disease, particularly multiple sclerosis because of ...
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  2. About Heinrich-Heine University Düsseldorf

    Heinrich-Heine University Düsseldorf

    Heinrich Heine University Düsseldorf is one of the younger higher education institutions in the state of North Rhine-Westphalia – founded in 1965. Since 1988 our university has carried the name of one of the city’s finest sons. Today around 25,000 students study at a modern campus under conditions ideally suited to academic life. As a campus university where everything is close together, all buildings including the University Hospital and the specialised libraries are easily reachable. Our university departments enjoy an excellent reputation due to an exceptionally high number of collaborative research centres. Moreover, the state capital Düsseldorf provides an attractive environment with a high quality of life.