1. Heidelberg Spectralis

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    1. Mentioned In 469 Articles

    2. Evaluation of patients with diffuse unilateral subacute neuroretinitis by spectral domain optical coherence tomography with enhanced depth imaging

      Evaluation of patients with diffuse unilateral subacute neuroretinitis by spectral domain optical coherence tomography with enhanced depth imaging

      Background: The purpose of this study was to determine the value of spectral domain ­optical coherence tomography (SD-OCT) in assessing patients with diffuse unilateral subacute neuroretinitis (DUSN). Methods: This was an observational case series with clinical imaging correlation performed at the Retina and Vitreous Institute of Londrina and State University of Londrina, Paraná, Brazil. The series comprised ten consecutive patients with a confirmed diagnosis of DUSN, ie, seven patients with late-stage disease and three with early-stage disease, who were assessed by SD-OCT for mean macular, retinal nerve fiber layer, and choroidal thickness using enhanced depth imaging software. Results: Comparing the ...

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    3. Spectral domain optical coherence tomography in patients after successful management of postoperative endophthalmitis following cataract surgery by pars plana vitrectomy

      Spectral domain optical coherence tomography in patients after successful management of postoperative endophthalmitis following cataract surgery by pars plana vitrectomy

      Background Acute severe postoperative endophthalmitis may lead to severe vision loss. The aim of this study was the analysis of macular microstructure imaged by spectral domain optical coherence tomography in patients after pars plana vitrectomy due to postcataract endophthalmitis. Methods A cross sectional study was carried out in 17 patients who had cataract surgery in both eyes and underwent unilateral pars plana vitrectomy due to postcataract endophthalmitis. Postoperative best corrected visual acuity was determined in both eyes. Evaluation of macular thickness, macular volume, peripapillary retinal nerve fiber layer thickness and choroidal thickness using enhanced depth imaging technique was performed by ...

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    4. A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy

      A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy
      ...onths 3, 6, 9 and 12. At each study visit best-corrected visual acuity (BCVA), FAF and SD-OCT imaging using a Spectralis HRA + OCT System were performed. FAF images were analyzed using the region overlay device. Planimet...
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    5. Relationship between the Lamina Cribrosa, Outer Retina, and Choroidal Thickness as Assessed Using Spectral Domain Optical Coherence Tomography

      Relationship between the Lamina Cribrosa, Outer Retina, and Choroidal Thickness as Assessed Using Spectral Domain Optical Coherence Tomography

      Purpose To evaluate the characteristics and relationship between peripapillary choroidal thickness (pCT), lamina cribrosa thickness (LCT), and peripapillary outer retinal layer thickness (pORT) as determined using spectral domain optical coherence tomography (SD-OCT) enhanced depth imaging (EDI). Methods In total, 255 participants were included (87 healthy subjects, 87 glaucoma suspects (GS), and 81 glaucoma cases). The pORT, defined as the thickness between the posterior outer plexiform layer and the retinal pigment epithelium (RPE) interface, and the pCT, between the outer margin of the RPE and the choroidal-scleral interface, were manually measured using EDI scanning of the circumpapillary retinal nerve fiber layer ...

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    6. Evaluation of the Macular, Peripapillary Nerve Fiber Layer and Choroid Thickness Changes in Behçet’s Disease with Spectral-Domain OCT

      Evaluation of the Macular, Peripapillary Nerve Fiber Layer and Choroid Thickness Changes in Behçet’s Disease with Spectral-Domain OCT
      ...nderwent macular, choroid, and peripapillary nerve fiber layer thickness analysis with Spectralis domain OCT (Spectralis OCT Heidelberg Engineering, Dossenheim, Germany). Main Outcome Measures . The differences in macula...
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    7. Calculating the predicted retinal thickness from spectral domain and time domain optical coherence tomography – comparison of different methods

      Calculating the predicted retinal thickness from spectral domain and time domain optical coherence tomography – comparison of different methods
      ...over S, Murthy RK, Brar VS, Chalam KV (2010) Comparison of retinal thickness in normal eyes using Stratus and Spectralis optical coherence tomography. Invest Ophthalmol Vis Sci 51:2644–2647 Kakinoki M, Sawada O, Sawada ...
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    8. An easy method to differentiate retinal arteries from veins by spectral domain optical coherence tomography: retrospective, observational case series

      An easy method to differentiate retinal arteries from veins by spectral domain optical coherence tomography: retrospective, observational case series
      ...ing retinal arteries from veins. Patients who underwent circular OCT scans centred at the optic disc using a Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany) were retrospectively reviewed. Individual retinal...
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    9. Non-invasive assessment of retinal alterations in mouse models of infantile and juvenile neuronal ceroid lipofuscinosis by spectral domain optical coherence tomography

      Non-invasive assessment of retinal alterations in mouse models of infantile and juvenile neuronal ceroid lipofuscinosis by spectral domain optical coherence tomography

      Introduction The neuronal ceroid lipofuscinoses constitute a group of fatal inherited lysosomal storage diseases that manifest in profound neurodegeneration in the CNS. Visual impairment usually is an early symptom and selective degeneration of retinal neurons has been described in patients suffering from distinct disease subtypes. We have previously demonstrated that palmitoyl protein thioesterase 1 deficient (Ppt1-/-) mice, a model of the infantile disease subtype, exhibit progressive axonal degeneration in the optic nerve and loss of retinal ganglion cells, faithfully reflecting disease severity in the CNS. Here we performed spectral domain optical coherence tomography (OCT) in Ppt1-/- and ceroid lipofuscinosis neuronal ...

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    10. University of Iowa Receiveds NIH Grant for Retinal Therapy Guided by 2-D OCT Imaging Analysis

      University of Iowa Receiveds NIH Grant for Retinal Therapy Guided by 2-D OCT Imaging Analysis
      ...nd assess its performance by comparison to expert analyses. Aim 2: Determine associations between standard 2D Spectralis OCT clinical readings from retinal specialists and quantitative SEAD- and layer-derived measures fr...
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    11. Agreement of Two Different Spectral Domain Optical Coherence Tomography Instruments for Retinal Nerve Fiber Layer Measurements

      Agreement of Two Different Spectral Domain  Optical Coherence Tomography Instruments for  Retinal Nerve Fiber Layer Measurements
      ...ots demonstrated that Spectralis thickness values were systematically larger than that of Cirrus. Conclusion: Spectralis OCT generates higher peripapillary RNFL thickness readings as compared to Cirrus OCT; this should b...
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  2. About Heidelberg Spectralis

    Heidelberg Spectralis

    Spectralis is a combination spectral Domain OCT and Angiography ophthalmic product made by Heidelberg Engineering.