1. Heidelberg Spectralis

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    1. Mentioned In 460 Articles

    2. An easy method to differentiate retinal arteries from veins by spectral domain optical coherence tomography: retrospective, observational case series

      An easy method to differentiate retinal arteries from veins by spectral domain optical coherence tomography: retrospective, observational case series
      ...ing retinal arteries from veins. Patients who underwent circular OCT scans centred at the optic disc using a Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany) were retrospectively reviewed. Individual retinal...
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    3. Non-invasive assessment of retinal alterations in mouse models of infantile and juvenile neuronal ceroid lipofuscinosis by spectral domain optical coherence tomography

      Non-invasive assessment of retinal alterations in mouse models of infantile and juvenile neuronal ceroid lipofuscinosis by spectral domain optical coherence tomography

      Introduction The neuronal ceroid lipofuscinoses constitute a group of fatal inherited lysosomal storage diseases that manifest in profound neurodegeneration in the CNS. Visual impairment usually is an early symptom and selective degeneration of retinal neurons has been described in patients suffering from distinct disease subtypes. We have previously demonstrated that palmitoyl protein thioesterase 1 deficient (Ppt1-/-) mice, a model of the infantile disease subtype, exhibit progressive axonal degeneration in the optic nerve and loss of retinal ganglion cells, faithfully reflecting disease severity in the CNS. Here we performed spectral domain optical coherence tomography (OCT) in Ppt1-/- and ceroid lipofuscinosis neuronal ...

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    4. University of Iowa Receiveds NIH Grant for Retinal Therapy Guided by 2-D OCT Imaging Analysis

      University of Iowa Receiveds NIH Grant for Retinal Therapy Guided by 2-D OCT Imaging Analysis
      ...nd assess its performance by comparison to expert analyses. Aim 2: Determine associations between standard 2D Spectralis OCT clinical readings from retinal specialists and quantitative SEAD- and layer-derived measures fr...
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    5. Agreement of Two Different Spectral Domain Optical Coherence Tomography Instruments for Retinal Nerve Fiber Layer Measurements

      Agreement of Two Different Spectral Domain  Optical Coherence Tomography Instruments for  Retinal Nerve Fiber Layer Measurements
      ...ots demonstrated that Spectralis thickness values were systematically larger than that of Cirrus. Conclusion: Spectralis OCT generates higher peripapillary RNFL thickness readings as compared to Cirrus OCT; this should b...
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    6. A Simplified Method to Measure Choroidal Thickness Using Adaptive Compensation in Enhanced Depth Imaging Optical Coherence Tomography

      A Simplified Method to Measure Choroidal Thickness Using Adaptive Compensation in Enhanced Depth Imaging Optical Coherence Tomography
      ...in optical coherence tomography (SD-OCT). Methods We measured CT in 31 subjects without ocular diseases using Spectralis EDI SD-OCT. The choroid-scleral interface of the acquired images was first enhanced using a post-pr...
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    7. Comparison of autofluorescence and optical coherence tomography findings in acute and chronic central serous chorioretinopathy

      Comparison of autofluorescence and optical coherence tomography findings in acute and chronic central serous chorioretinopathy

      AIM: To discuss and compare the fundus autofluorescence (FAF) and optical coherence tomography (OCT) in acute or chronic central serous chorioretinopathy (CSCR). METHODS: Medical records of 100 cases of CSCR were reviewed. Acute and chronic cases were evaluated according to the duration of decreased visual acuity, serous retinal detachment (RD) and focal leakage on fluorescein angiography (FA). Chi-square test was used for statistical analysis. RESULTS: Forty cases had acute and 60 cases had chronic CSCR. FAF showed focal hypo-autofluorescence in 34 (85%) and iso-autofluorescence in 6 (15%) of acute cases and hypo-autofluorescence in 51 (85%), hyper-autofluorescence in 6 (10%) and ...

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    8. Morphological changes in spectral domain optical coherence tomography guided bevacizumab injections in wet age-related macular degeneration, 12-months results

      Morphological changes in spectral domain optical coherence tomography guided bevacizumab injections in wet age-related macular degeneration, 12-months results
      ... and if a feature was present in 19/19 scans it was = 100% [Figure 3]. We employed the commercially available Spectralis software to measure automatically central retinal thickness. The boundaries of the measurements wer...
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    9. Intra-operative OCT devices for ophthalmic use: an overview

      Intra-operative OCT devices for ophthalmic use: an overview

      It is feasible to bring the currently most used examination method in ophthalmology, optical coherence tomography (OCT), into ophthalmic surgery to enhance information and control for the surgeon and increase outcome for the patient. In this overview, the currently commercially available OCT devices intending intra-operative OCT imaging are described. Further experience with these systems might not only aid in solving current problems but also open our minds to detect processes so far unknown and help answer questions so far unaddressed.

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    10. Potential new diagnostic tool for Alzheimer's disease using a linear discriminant function for Fourier domain optical coherence tomography

      Potential new diagnostic tool for Alzheimer's disease using a linear discriminant function for Fourier domain optical coherence tomography
      ...the LDF yielded the highest sensitivity values. Conclusions: Measurements of RNFL thickness obtained with the Spectralis OCT device differentiated between healthy and AD individuals. Based on the area under the ROC curve...
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    11. Structure-Function Correlations in Glaucoma Using Matrix and Standard Automated Perimetry Versus Time Domain and Spectral Domain OCT devices

      Structure-Function Correlations in Glaucoma Using Matrix and Standard Automated Perimetry Versus Time Domain and Spectral Domain OCT devices
      ...5. Regarding FDT Matrix, the correlation ranged from 0.40 to 0.79 with Stratus OCT and from 0.39 to 0.79 with Spectralis OCT. Stronger correlations were found in the overall measurements and the arcuate sectors for both ...
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  2. About Heidelberg Spectralis

    Heidelberg Spectralis

    Spectralis is a combination spectral Domain OCT and Angiography ophthalmic product made by Heidelberg Engineering.