1. Heidelberg Engineering

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    1. Mentioned In 499 Articles

    2. Automated detection of Schlemm's canal in spectral-domain optical coherence tomography

      Automated detection of Schlemm's canal in spectral-domain optical coherence tomography

      Recent advances in optical coherence tomography (OCT) technology allow in vivo imaging of the complex network of intra-scleral aqueous veins in the anterior segment of the eye. Pathological changes in this network, draining the aqueous humor from the eye, are considered to play a role in intraocular pressure elevation, which can lead to glaucoma, one of the major causes of blindness in the world. Through acquisition of OCT volume scans of the anterior eye segment, we aim at reconstructing the three dimensional network of aqueous veins in healthy and glaucomatous subjects. A novel algorithm for segmentation of the three-dimensional (3D ...

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    3. COLOCALIZATION ERROR BETWEEN THE SCANNING LASER OPHTHALMOSCOPE INFRARED REFLECTANCE AND OPTICAL COHERENCE TOMOGRAPHY IMAGES OF THE HEIDELBERG SPECTRALIS

      COLOCALIZATION ERROR BETWEEN THE SCANNING LASER OPHTHALMOSCOPE INFRARED REFLECTANCE AND OPTICAL COHERENCE TOMOGRAPHY IMAGES OF THE HEIDELBERG SPECTRALIS

      Purpose: To examine the colocalization error between the infrared reflectance (IR) scanning laser ophthalmoscope (SLO) and spectral domain optical coherence tomography (SD-OCT) images of the Heidelberg Spectralis. Methods: The IR and corresponding horizontal raster SD-OCT images were compared in 10 healthy volunteers examined with 3 Heidelberg Spectralis + OCT instruments. The center points of retinal vessels selected by random uniform sampling in scanning laser ophthalmoscope-IR images were compared with colocalizing points in corresponding SD-OCT images by two masked readers. The error of colocalization was measured in the SD-OCT image. The point positions were recorded using Cartesian coordinates measured in microns. The ...

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    4. Binarization of enhanced depth imaging optical coherence tomographic images of an eye with Wyburn-Mason syndrome: a case report

      Binarization of enhanced depth imaging optical coherence tomographic images of an eye with Wyburn-Mason syndrome: a case report

      Background To report a thicker choroid and larger choroidal luminal area in an eye with Wyburn-Mason syndrome. To the best of our knowledge, this is the first report demonstrating an increase in the choroidal thickness and the luminal area in a case of Wyburn-Mason syndrome. In addition, we report the changing appearance of retinal arteriovenous malformations over a 16-year period. Case presentation A 27-year-old woman, who was diagnosed with Wyburn-Mason syndrome at age 11 years, visited our clinic. Her best-corrected visual acuity was 20/12.5 in the right eye and light perception in the left eye. Severely dilated, tortuous ...

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    5. Assessment of lower tear meniscus measurements obtained with Keratograph and agreement with Fourier-domain optical-coherence tomography

      Assessment of lower tear meniscus measurements obtained with Keratograph and agreement with Fourier-domain optical-coherence tomography

      Aims To compare intraobserver repeatability and interobserver and intersession reproducibility of lower tear meniscus height measurements (LTMH) obtained with the new Keratograph 5M and a Fourier-domain optical-coherence tomography (OCT; Spectralis OCT) and to assess the agreement between the two devices. Methods This is a observational cross-sectional study. Thirty eyes of 30 normal subjects were randomly imaged twice with both devices in our setting. Two examiners randomly made LTMH measurements using the devices. To assess intraobserver repeatability and interobserver and intersession reproducibility within-subject SD (S w ), test–retest repeatability, coefficient of variation (CoV) and intraclass correlation coefficients (ICCs) were calculated. Agreement ...

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    6. Relationship of inferior oblique overaction to macular and subfoveal choroidal thickness

      Relationship of inferior oblique overaction to macular and subfoveal choroidal thickness

      Purpose To evaluate the macular and subfoveal choroidal thickness of eyes with inferior oblique muscle overaction (IOOA) using enhanced depth imaging spectral domain optical coherence tomography (EDI SD-OCT). Methods The measurements of macular and subfoveal choroidal thickness obtained by EDI SD-OCT of patients with IOOA (24 patients) were compared with those of age- and sex-matched controls (25 subjects). Results There were no morphological abnormalities of the macula in patients with IOOA or in control subjects. There were no statistically significant differences in macular and subfoveal choroidal thickness between the eyes with IOOA and the eyes of the control subjects ( P ...

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    7. Macular optical coherence tomography in patients with unilateral optic nerve hypoplasia

      Macular optical coherence tomography in patients with unilateral optic nerve hypoplasia

      Purpose To characterize the extent and location of macular thinning in patients with unilateral optic nerve hypoplasia (ONH) as compared to the contralateral normal eye. Methods The medical records of patients with unilateral ONH who underwent spectral domain optical coherence tomography (SD-OCT) of the macula were retrospectively reviewed. SD-OCT scans were manually segmented by 3 observers in 3 macular regions (superior, central, inferior). Boundaries identified included the inner limiting membrane, the junction between the inner nuclear layer and outer plexiform layer, and the neural retina–retinal pigment epithelium interface. Using custom MATLAB software, inner and outer retinal thickness profiles were ...

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    8. Fundus autofluorescence and optical coherence tomography findings in glutathione synthetase deficiency

      Fundus autofluorescence and optical coherence tomography findings in glutathione synthetase deficiency

      We report the autofluorescence pattern and optical coherence tomography (OCT) characteristics in a 6-year-old boy with glutathione synthetase deficiency. The patient underwent complete ophthalmological examination, including full-field electroretinography, visual evoked potentials, fundus autofluorescence, and OCT imaging. Electrophysiological studies showed time-delay and subnormal responses. Fundus autofluorescence imaging revealed increased parafoveal autofluorescence compared to normal, and OCT showed alteration of photoreceptor and retinal pigment epithelium layers in the parafoveal region.

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    9. Comparison between the measurements of different parameters obtained from optic nerve head analysis by using Heidelberg retinal tomography (HRT3) and Optical coherence tomography (Stratus OCT)

      Comparison between the measurements of different parameters obtained from optic nerve head analysis by using Heidelberg retinal tomography (HRT3) and Optical coherence tomography (Stratus OCT)

      Purpose: A cross-sectional prospective nonrandomized study was undertaken to find out whether Heidelberg retinal tomography (HRT3) and Optical coherence tomography (Stratus OCT) could be used interchangeably for the measurement of different parameters of optic nerve head in clinical practice. Materials and Methods: Measurements of disc area, cup area, rim area and cup-disc area ratio were obtained with the HRT3 and Stratus OCT printouts in 18 patients aged 20 to 70 years. True agreements between methods in measuring disc area, cup area, rim area and cup-disc area ratio were assessed using Bland-Altman statistical analysis. Eighteen patients with a mean age of ...

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    10. New neuroretinal rim analysis with spectral domain optical coherence tomography, Spectralis (Heidelberg Engineering, Germany). Preliminary study

      New neuroretinal rim analysis with spectral domain optical coherence tomography, Spectralis (Heidelberg Engineering, Germany). Preliminary study
      ... After a precise localization of the OD center, 24 radial scans of the ONH are taken with the Spectralis OCT (Heidelberg Engineering, Germany). From the 48 measurements of BMO-MRW, the mean thickness as well as that in e...
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    11. Comparison of penetration depth in choroidal imaging using swept source vs spectral domain optical coherence tomography

      Comparison of penetration depth in choroidal imaging using swept source vs spectral domain optical coherence tomography

      Purpose To compare signal penetration depth and deep structure-visualization of swept source (SS) and spectral domain (SD)-optical coherence tomography (OCT) with and without enhanced depth imaging (EDI) and B-scan averaging modes. Methods Volume scans were obtained from 20 eyes of healthy volunteers by DRI OCT-1, Spectralis using EDI and B-scan averaging, and Cirrus HD-OCT. The signal penetration depth was measured as the distance between the retinal pigment epithelium and the deepest visible anatomical structure at the foveal center. Visibility and contrast of the choroidoscleral junction and of vascular details within the choroid were assessed across the entire volume using ...

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    12. 1-15 of 499 1 2 3 4 ... 32 33 34 »
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  2. About Heidelberg Engineering

    Heidelberg Engineering

    Heidelberg Engineering. Ophthalmology Systems. Heidelberg Engineering has paved the way for quantitative retinal imaging in glaucoma management. The Heidelberg Retina Tomograph was the first instrument of its kind available on the market for the routine glaucoma exam. It follows that Heidelberg Engineering has the longest history and the most experience and knowledge of the subject. The high quality and reproducibility of our products have been proven over time by the accuracy and consistency of glaucoma follow-up exams.
    The reason for this is that Heidelberg Engineering has ensured that there is a solid scientific base to all products.
    The company has always been involved in basic research projects, and our technical knowledge is unsurpassed. Heidelberg Engineering is an extremely innovative company. It is the integrity of research and consistency of approach that enable our products to be used with confidence in the clinical environment. Our track record of product development is exceptional! Look at the development milestones achieved during the past 10 years.

  3. Quotes about Heidelberg Engineering

    1. I am becoming a big fan of spectral-domain OCT, especially Spectralis [Heidelberg Engineering, Vista, Calif.]...To this point with time-domain OCT, I have not been convinced that you can use this technology to follow patients over time. Now, with the faster image acquisition and better axial resolution we see with SD OCT, there is better quantitative peripapillary retinal nerve fiber layer measurement for glaucoma management. The improved accuracy of the OCT segmentation allows for better long-term evaluation of patients.
      Leon W. Herndon in Delving into glaucoma
    2. The concept of Heidelberg Engineering has always been to offer system platforms that customers can expand and upgrade with modules as needed, that are flexible and able grow with the organization...Our strategy to offer sustainable solutions has proven to be highly relevant to customers and it makes sense to follow this pathway with HEYEX PACS. Whether you want to integrate into major IT-infrastructures, interface with Electronic Health Record (EHR) systems, review imaging data from mobile devices or centralize all data; the possibilities will be virtually unlimited. Our goal is to enhance the performance and workflow efficiency of eye care professionals. I am confident that this will translate into better patient care and practice growth.
      Kester Nahen in HEYEX PACS™: The Next Generation Image Management and Device Integration Platform