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    1. Mentioned In 456 Articles

    2. Reproducibility of Spectral-Domain Optical Coherence Tomography Retinal Thickness Measurements and Conversion to Equivalent Time-Domain Metrics in Diabetic Macular Edema

      Reproducibility of Spectral-Domain Optical Coherence Tomography Retinal Thickness Measurements and Conversion to Equivalent Time-Domain Metrics in Diabetic Macular Edema
      ...main (TD) (Stratus; Carl Zeiss Meditec) and spectral-domain (SD) (Cirrus; Carl Zeiss Meditec, and Spectralis; Heidelberg Engineering) instruments and formulate equations to convert retinal thickness measurements from SD-...
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    3. Assessment of β-zone peripapillary atrophy by optical coherence tomography and scanning laser ophthalmoscopy imaging in glaucoma patients

      Assessment of β-zone peripapillary atrophy by optical coherence tomography and scanning laser ophthalmoscopy imaging in glaucoma patients

      Purpose: To assess β-zone peripapillary atrophy (β-PPA) using spectral domain optical coherence tomography (SD-OCT), scanning laser ophthalmoscopy (SLO), and fundus autofluorescence (FAF) imaging in patients with primary open-angle glaucoma with advanced glaucomatous visual field defects. Methods: A consecutive, prospective series of 82 study eyes with primary open-angle glaucoma were included in this study. All study participants underwent a full ophthalmic examination followed by SD-OCT, wide-field SLO, and FAF imaging of the optic nerve head and the peripapillary region. Results: Eighty-four glaucomatous eyes were included in our prospective study. Correlation analyses for horizontally and vertically obtained β-PPA for all three imaging ...

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    4. Correlation of Choroidal Thickness and Volume Measurements with Axial Length and Age Using Swept Source Optical Coherence Tomography and Optical Low-Coherence Reflectometry

      Correlation of Choroidal Thickness and Volume Measurements with Axial Length and Age Using Swept Source Optical Coherence Tomography and Optical Low-Coherence Reflectometry

      Purpose . To report choroidal thickness and volume in healthy eyes using swept source optical coherence tomography (SS-OCT). Methods . A prospective observational study of 122 patients examined with swept source OCT (DRI-OCT, Topcon, Japan). In each eye, we performed 256 horizontal scans, 12 mm in length and centered on the fovea. We calculated choroidal thickness manually with a built-in caliper and automatically using DRI-OCT mapping software. Choroidal volume was also automatically calculated. We measured axial length with optical low-coherence reflectometry (Lenstar LS 900, Haag-Streit, Switzerland). Results . The choroid has focally increased thickness under the fovea. Choroid was thinnest in the outer ...

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    5. Evaluation of patients with diffuse unilateral subacute neuroretinitis by spectral domain optical coherence tomography with enhanced depth imaging

      Evaluation of patients with diffuse unilateral subacute neuroretinitis by spectral domain optical coherence tomography with enhanced depth imaging

      Background: The purpose of this study was to determine the value of spectral domain ­optical coherence tomography (SD-OCT) in assessing patients with diffuse unilateral subacute neuroretinitis (DUSN). Methods: This was an observational case series with clinical imaging correlation performed at the Retina and Vitreous Institute of Londrina and State University of Londrina, Paraná, Brazil. The series comprised ten consecutive patients with a confirmed diagnosis of DUSN, ie, seven patients with late-stage disease and three with early-stage disease, who were assessed by SD-OCT for mean macular, retinal nerve fiber layer, and choroidal thickness using enhanced depth imaging software. Results: Comparing the ...

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    6. Study of Retinal Nerve Fibre Layer Thickness in Type 2 Diabetes Mellitus by 3-Dimensional Optical Coherence Tomography from Eastern India

      Study of Retinal Nerve Fibre Layer Thickness in Type 2 Diabetes Mellitus by 3-Dimensional Optical Coherence Tomography from Eastern India

      Three dimensional optical coherence tomography (OCT) is a novel technique to diagnose retinal disorders. In diabetes, loss of retinal neurons is said to be an early event. We did a small pilot study from Eastern India to find the usefulness of OCT in detecting changes in retinal nerve fibre layer (RNFL) in diabetics. We selected adult type 2 diabetics without overt retinopathy. Patients aged more than 60 or with pre-existing problems like glaucoma or vasculitis were excluded. RNFL thickness was measured using HRA-OCT Spectralis analyser. A 12º area around optic nerve head was analysed and depth of each quadrant was ...

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    7. Spectral domain optical coherence tomography in patients after successful management of postoperative endophthalmitis following cataract surgery by pars plana vitrectomy

      Spectral domain optical coherence tomography in patients after successful management of postoperative endophthalmitis following cataract surgery by pars plana vitrectomy

      Background Acute severe postoperative endophthalmitis may lead to severe vision loss. The aim of this study was the analysis of macular microstructure imaged by spectral domain optical coherence tomography in patients after pars plana vitrectomy due to postcataract endophthalmitis. Methods A cross sectional study was carried out in 17 patients who had cataract surgery in both eyes and underwent unilateral pars plana vitrectomy due to postcataract endophthalmitis. Postoperative best corrected visual acuity was determined in both eyes. Evaluation of macular thickness, macular volume, peripapillary retinal nerve fiber layer thickness and choroidal thickness using enhanced depth imaging technique was performed by ...

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    8. A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy

      A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy

      Purpose To identify reliable criteria based on spectral-domain optical coherence tomography (SD-OCT) to monitor disease progression in geographic atrophy due to age-related macular degeneration (AMD) compared with lesion size determination based on fundus autofluorescence (FAF). Design Prospective longitudinal observational study Methods Setting :Institutional. Study population A total of 48 eyes in 24 patients with geographic atrophy. Observation Procedures Eyes with geographic atrophy were included and examined at baseline and months 3, 6, 9 and 12. At each study visit best-corrected visual acuity (BCVA), FAF and SD-OCT imaging using a Spectralis HRA + OCT System were performed. FAF images were analyzed using ...

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    9. Relationship between the Lamina Cribrosa, Outer Retina, and Choroidal Thickness as Assessed Using Spectral Domain Optical Coherence Tomography

      Relationship between the Lamina Cribrosa, Outer Retina, and Choroidal Thickness as Assessed Using Spectral Domain Optical Coherence Tomography

      Purpose To evaluate the characteristics and relationship between peripapillary choroidal thickness (pCT), lamina cribrosa thickness (LCT), and peripapillary outer retinal layer thickness (pORT) as determined using spectral domain optical coherence tomography (SD-OCT) enhanced depth imaging (EDI). Methods In total, 255 participants were included (87 healthy subjects, 87 glaucoma suspects (GS), and 81 glaucoma cases). The pORT, defined as the thickness between the posterior outer plexiform layer and the retinal pigment epithelium (RPE) interface, and the pCT, between the outer margin of the RPE and the choroidal-scleral interface, were manually measured using EDI scanning of the circumpapillary retinal nerve fiber layer ...

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    10. Evaluation of the Macular, Peripapillary Nerve Fiber Layer and Choroid Thickness Changes in Behçet’s Disease with Spectral-Domain OCT

      Evaluation of the Macular, Peripapillary Nerve Fiber Layer and Choroid Thickness Changes in Behçet’s Disease with Spectral-Domain OCT
      ...r, choroid, and peripapillary nerve fiber layer thickness analysis with Spectralis domain OCT (Spectralis OCT Heidelberg Engineering, Dossenheim, Germany). Main Outcome Measures . The differences in macular, choroid, and...
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    11. Calculating the predicted retinal thickness from spectral domain and time domain optical coherence tomography – comparison of different methods

      Calculating the predicted retinal thickness from spectral domain and time domain optical coherence tomography – comparison of different methods

      Purpose To compare the accuracy of different methods of calculating predicted central retinal thickness values in order to allow comparison between results of spectral-domain optical coherence tomography (SD-OCT) and time-domain OCT (TD-OCT) devices. Methods In a prospective cohort study, 100 consecutive healthy individuals without ocular disease underwent sequential scanning with SD-OCT (Spectralis OCT) and TD-OCT (Stratus OCT). A group of 60 eyes was used to generate the conversion equations, which were tested on the remaining 140 eyes. Four equations were used: 1. Mean difference between SD-OCT and TD-OCT; 2. Multiplying a ratio by the original retinal thickness; 3. Linear regression ...

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    12. 1-15 of 456 1 2 3 4 ... 29 30 31 »
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  2. About Heidelberg Engineering

    Heidelberg Engineering

    Heidelberg Engineering. Ophthalmology Systems. Heidelberg Engineering has paved the way for quantitative retinal imaging in glaucoma management. The Heidelberg Retina Tomograph was the first instrument of its kind available on the market for the routine glaucoma exam. It follows that Heidelberg Engineering has the longest history and the most experience and knowledge of the subject. The high quality and reproducibility of our products have been proven over time by the accuracy and consistency of glaucoma follow-up exams.
    The reason for this is that Heidelberg Engineering has ensured that there is a solid scientific base to all products.
    The company has always been involved in basic research projects, and our technical knowledge is unsurpassed. Heidelberg Engineering is an extremely innovative company. It is the integrity of research and consistency of approach that enable our products to be used with confidence in the clinical environment. Our track record of product development is exceptional! Look at the development milestones achieved during the past 10 years.

  3. Quotes about Heidelberg Engineering

    1. I am becoming a big fan of spectral-domain OCT, especially Spectralis [Heidelberg Engineering, Vista, Calif.]...To this point with time-domain OCT, I have not been convinced that you can use this technology to follow patients over time. Now, with the faster image acquisition and better axial resolution we see with SD OCT, there is better quantitative peripapillary retinal nerve fiber layer measurement for glaucoma management. The improved accuracy of the OCT segmentation allows for better long-term evaluation of patients.
      Leon W. Herndon in Delving into glaucoma