1. Harvard University

    0 Comments Leave a Comment

    1-15 of 1043 1 2 3 4 ... 68 69 70 »
    1. Mentioned In 1043 Articles

    2. Three-dimensional opto-thermo-mechanical model for predicting photo-thermal optical coherence tomography responses in multilayer geometries

      Three-dimensional opto-thermo-mechanical model for predicting photo-thermal optical coherence tomography responses in multilayer geometries
      Photothermal optical coherence tomography (PT-OCT) is a functional extension of OCT with the ability to generate qualitative maps of molecular absorptions co-registered with the micron-resolution structural tomograms of OCT. Obtaining refined insight into chemical information from PT-OCT images, however, requires solid understanding of the multifactorial physics behind generation of PT-OCT signals and their dependence on system and sample parameters. Such understanding is needed to decouple the various physical effects involved ...
      Read Full Article
    3. A novel algorithm for multiplicative speckle noise reduction in ex vivo human brain OCT images

      A novel algorithm for multiplicative speckle noise reduction in ex vivo human brain OCT images
      Optical coherence tomography (OCT) images of ex vivo human brain tissue are corrupted by multiplicative speckle noise that degrades the contrast to noise ratio (CNR) of microstructural compartments. This work proposes a novel algorithm to reduce noise corruption in OCT images that minimizes the penalized negative log likelihood of gamma distributed speckle noise. The proposed method is formulated as a majorize-minimize problem that reduces to solving an iterative regularized least ...
      Read Full Article
    4. Ultrahigh resolution spectral-domain optical coherence tomography using the 1000-1600 nm spectral band

      Ultrahigh resolution spectral-domain optical coherence tomography using the 1000-1600 nm spectral band
      Ultrahigh resolution optical coherence tomography (UHR-OCT) can image microscopic features that are not visible with the standard OCT resolution of 5-15 m. In previous studies, high-speed UHR-OCT has been accomplished within the visible (VIS) and near-infrared (NIR-I) spectral ranges, specifically within 550-950 nm. Here, we present a spectral domain UHR-OCT system operating in a short-wavelength infrared (SWIR) range from 1000 to 1600 nm using a supercontinuum light source and an ...
      Read Full Article
    5. Juxtapapillary Choroidal Neovascular Membrane as a Complication of Optic Disc Drusen: Multimodal Imaging With Swept Source-Optical Coherence Tomography and Optical Coherence Tomography Angiography

      Juxtapapillary Choroidal Neovascular Membrane as a Complication of Optic Disc Drusen: Multimodal Imaging With Swept Source-Optical Coherence Tomography and Optical Coherence Tomography Angiography
      A 55-year-old Caucasian man presented to the neuro-ophthalmology department for follow-up evaluation due to long-standing bilateral optic nerve head drusen (ONHD). On examination, the BCVA was 20/20-2 in both eyes. Dilated fundus examination revealed extensive ONHD in both eyes, retinal hemorrhages, exudates inferonasal to the macula, and macular edema inferotemporal to the disc margin. Automated visual field testing revealed generalized depression in both eyes. Late phase leakage was observed ...
      Read Full Article
    6. Optical coherence tomography in coronary atherosclerosis assessment and intervention

      Optical coherence tomography in coronary atherosclerosis assessment and intervention
      Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in ...
      Read Full Article
    7. Postdoctoral Research Fellowships (OCT Image Processing and Machine Learning) at Massachusetts General Hospital

      Postdoctoral Research Fellowships (OCT Image Processing and Machine Learning)  at Massachusetts General Hospital
      ...de at the rank of postdoctoral fellow at Harvard Medical School. MGHs role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for dev...
      Read Full Article
    8. Extended depth of focus by self-imaging wavefront division with the mirror tunnel

      Extended depth of focus by self-imaging wavefront division with the mirror tunnel
      The mirror tunnel is a component used to extend the depth of focus for compact imaging probes used in endoscopic optical coherence tomography (OCT). A fast and accurate method for mirror tunnel probe simulation, characterization, and optimization is needed, with the aim of reconciling wave- and ray-optics simulation methods and providing a thorough description of the physical operating principle of the mirror tunnel. BeamLab software, employing the beam propagation method ...
      Read Full Article
    9. Apparatus, device and method for capsule microscopy

      Apparatus, device and method for capsule microscopy
      An exemplary apparatus for obtaining data for at least one portion within at least one luminal or hollow sample can be provided. For example, the apparatus can include a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the portion(s). The apparatus can also include a wavelength dispersive second arrangement, which can be configured to disperse the electromagnetic radiation(s). A housing can be ...
      Read Full Article
    10. RF properties of circular-ranging OCT signals

      RF properties of circular-ranging OCT signals
      Circular-ranging optical coherence tomography (CROCT) systems that use a timestepped frequency comb source generate interference fringe signals that are more complex than those of a conventional sweptsource OCT system. Here, we define a common terminology for describing these signals, and we develop a mathematical framework that relates the radio-frequency (RF) properties of these fringe signals to the parameters of the frequency comb source. With this framework, we highlight non-intuitive mechanisms ...
      Read Full Article
    11. Raman microspectroscopy/micro-optical coherence tomography approach for chairside diagnosis of periodontal diseases - A pilot study

      Raman microspectroscopy/micro-optical coherence tomography approach for chairside diagnosis of periodontal diseases - A pilot study
      Background: Our objective was to develop and test a combined Raman microspectroscopy (RMS) and micro-optical coherence tomography (OCT) approach for chairside quantification of gingival collagen, DNA, epithelium and connective tissue. We hypothesized that a high-resolution RMS/OCT can characterize healthy and inflamed periodontal tissues for diagnosis and disease activity monitoring. Methods: A prototype instrument was developed, tested ex-vivo on gingival specimens and optimized for in-vivo intraoral use. The primary outcome ...
      Read Full Article
    12. Relationship between axial resolution and signal-to-noise ratio in optical coherence tomography

      Relationship between axial resolution and signal-to-noise ratio in optical coherence tomography
      In optical coherence tomography (OCT), axial resolution and signal-to-noise ratio (SNR) are typically viewed as uncoupled parameters. We show that this is true only for mirror-like surfaces and that in diffuse scattering samples such as biological tissues there is an inherent coupling between axial resolution and measurement SNR. We explain the origin of this coupling and demonstrate that it can be used to achieve increased imaging penetration depth at the ...
      Read Full Article
    13. 1-15 of 1043 1 2 3 4 ... 68 69 70 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Harvard University

    Harvard University

    Harvard University is a private university in Cambridge, Massachusetts, U.S. Founded in 1636 by the colonial Massachusetts legislature Harvard is the oldest institution of higher learning in the United States.  Harvard Medical School  is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts.  Schepens Eye Research Institute fights blindness by developing new technologies, therapies and knowledge to retain and restore vision. Through a continuum of discovery, the Institute works toward a future in which blindness is prevented, alleviated, and, ultimately, cured.