1. Harvard University

    0 Comments Leave a Comment

    1-15 of 429 1 2 3 4 ... 27 28 29 »
    1. Mentioned In 429 Articles

    2. Vitreous Hyper-Reflective Dots in Optical Coherence Tomography and Cystoid Macular Edema after Uneventful Phacoemulsification Surgery

      Vitreous Hyper-Reflective Dots in Optical Coherence Tomography and Cystoid Macular Edema after Uneventful Phacoemulsification Surgery

      Purpose To report the observation of hyper-reflective dots in the vitreous cavity using spectral domain optical coherence tomography (SD-OCT) after uneventful phacoemulsification cataract surgery and to investigate their association with cystoid macular edema (CME). Materials and Methods Medical records of consecutive Asian patients who had no preoperative retinopathy and underwent uneventful phacoemulsification cataract surgery from March 2012 through February 2013 were reviewed. SD-OCTs were performed before, 1 week, and 1 month after surgery. The number of vitreous hyper-reflective dots (VHDs) was counted in 5 OCT images of high-definition 5-line raster scans. The development of CME was assessed using postoperative 1-month ...

      Read Full Article
    3. MGH Receives NIH Grant for Development of a Preclinical Optical Frequency Domain Angiography Instrument

      MGH Receives NIH Grant for Development of a Preclinical Optical Frequency Domain Angiography Instrument

      Massachusetts General Hospital Receives a 2014 NIH Grant for $467,429 for Development of a Preclinical Optical Frequency Domain Angiography Instrument. The principal investigator is Benjamin Vakoc. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. Tumor-induced angiogenesis plays a central role in the progression of tumors to malignancy, provides the critical transport of blood-born therapies into the tumor space, and supplies oxygen to effectuate oxygen-dependent radiological and light-based therapies. Pre-clinical research in tumor angiogenesis and tumor microvascular function has traditionally relied on histological methods, which suffer from well-known limitations, or fluorescence-based ...

      Read Full Article
    4. Postdoctoral Research Fellowships in Optical Coherence Tomography at Wellman Center for Photomedicine Massachusetts General Hospital

      Postdoctoral Research Fellowships in Optical Coherence Tomography at Wellman Center for Photomedicine Massachusetts General Hospital
      ...de at the rank of postdoctoral fellow at Harvard Medical School. MGHs role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for dev...
      Read Full Article
    5. Spatial Heterogeneity of Neoatherosclerosis, and its Relationship with Neovascularization and Adjacent Plaque Characteristics: Optical Coherence Tomography Study

      Spatial Heterogeneity of Neoatherosclerosis, and its Relationship with Neovascularization and Adjacent Plaque Characteristics: Optical Coherence Tomography Study
      ...l School, Boston, MA , * Iris McNulty, RN Affiliations + Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA , * Hang Lee, PhD Affiliations + Biostatistics, Massachusetts General Hospi...
      Read Full Article
    6. Postdoctoral Optical Engineer in Biomedical Optics at Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School

      Postdoctoral Optical Engineer  in Biomedical Optics at Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School
      ...ter for Photomedicine. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for the development of cutting edge technologies...
      Read Full Article
    7. Distinct Morphological Features of Ruptured Culprit Plaque for Acute Coronary Events Compared to those with Silent Rupture and Thin-Cap Fibroatheroma: a Combined Optical Coherence Tomography and Intravascular Ultrasound Study

      Distinct Morphological Features of Ruptured Culprit Plaque for Acute Coronary Events Compared to those with Silent Rupture and Thin-Cap Fibroatheroma: a Combined Optical Coherence Tomography and Intravascular Ultrasound Study

      Objectives To identify specific morphological characteristics of ruptured culprit plaques (RCP) responsible for acute events, and compare them with ruptured non-culprit plaques (RNCP) and non-ruptured thin-cap fibroatheroma (TCFA) in patients presenting with acute coronary syndromes (ACS). Background Non-ruptured TCFA and multiple ruptured plaques are detected in the same patients with ACS. It remains unknown whether certain morphological characteristics determine rupture of TCFA and subsequently result in ACS. Methods We analyzed 126 plaques (RCP=49, RNCP=19, TCFA=58) from 82 ACS patients using optical coherence tomography (OCT) and intravascular ultrasound (IVUS). Fibrous cap thickness was determined by OCT. Plaque burden ...

      Read Full Article
    8. Feature Of The Week 3/2/14: Erasmus MC Investigates Fusion of OCT and Coronary Angiography for Accurate Assessment of the Local Blood Flow Patterns

      Feature Of The Week 3/2/14: Erasmus MC Investigates Fusion of OCT and Coronary Angiography for Accurate Assessment of the Local Blood Flow Patterns

      Intravascular ultrasound (IVUS)-based reconstructions have been traditionally used to examine the effect of endothelial shear stress (ESS) on neointimal formation. The aim of this analysis is to compare the association between ESS and neointimal thickness (NT) in models obtained by the fusion of optical coherence tomography (OCT) and coronary angiography and in the reconstructions derived by the integration of IVUS and coronary angiography. We analyzed data from six patients implanted with an Absorb bioresorbable vascular scaffold that had biplane angiography, IVUS and OCT investigation at baseline and 6 or 12 months follow-up. The IVUS and OCT follow-up data were ...

      Read Full Article
    9. Effect of the Endothelial Shear Stress Patterns on Neointimal Proliferation Following Drug-Eluting Bioresorbable Vascular Scaffold Implantation : An Optical Coherence Tomography Study

      Effect of the Endothelial Shear Stress Patterns on Neointimal Proliferation Following Drug-Eluting Bioresorbable Vascular Scaffold Implantation : An Optical Coherence Tomography Study

      Objectives The goal of this study was to investigate the effect of endothelial shear stress (ESS) on neointimal formation following an Absorb bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, California) implantation. Background Cumulative evidence, derived from intravascular ultrasound–based studies, has demonstrated a strong association between local ESS patterns and neointimal formation in bare-metal stents, whereas in drug-eluting stents, there are contradictory data about the effect of ESS on the vessel wall healing process. The effect of ESS on neointimal development following a bioresorbable scaffold implantation remains unclear. Methods Twelve patients with an obstructive lesion in a relatively straight ...

      Read Full Article
    10. A Quantum Field Approach for Advancing Optical Coherence Tomography Part I: First Order Correlations, Single Photon Interference, And Quantum Noise

      A Quantum Field Approach for Advancing Optical Coherence Tomography Part I: First Order Correlations, Single Photon Interference, And Quantum Noise

      Optical coherence tomography has become an important imaging technology in cardiology and ophthalmology, with other applications under investigations. Major advances in optical coherence tomography (OCT) imaging are likely to occur through a quantum field approach to the technology. In this paper, which is the first part in a series on the topic, the quantum basis of OCT first order correlations is expressed in terms of full field quantization. Specifically first order correlations are treated as the linear sum of single photon interferences along indistinguishable paths. Photons and the electromagnetic (EM) field are described in terms of quantum harmonic oscillators. While ...

      Read Full Article
    11. A rapid, dispersion-based wavelength-stepped and wavelength-swept laser for optical coherence tomography

      A rapid, dispersion-based wavelength-stepped and wavelength-swept laser for optical coherence tomography

      Abstract: Optical-domain subsampling enables Fourier-domain OCT imaging at high-speeds and extended depth ranges while limiting the required acquisition bandwidth. To perform optical-domain subsampling, a wavelength-stepped rather than a wavelength-swept source is required. This preliminary study introduces a novel design for a rapid wavelength-stepped laser source that uses dispersive fibers in combination with a fast lithium-niobate modulator to achieve wavelength selection. A laser with 200 GHz wavelength-stepping and a sweep rate of 9 MHz over a 94 nm range at a center wavelength of 1550 nm is demonstrated. A reconfiguration of this source design to a continuous wavelength-swept light for conventional ...

      Read Full Article
    12. Esophageal-guided biopsy with volumetric laser endomicroscopy and laser cautery marking: a pilot clinical study

      Esophageal-guided biopsy with volumetric laser endomicroscopy and laser cautery marking: a pilot clinical study

      Background Biopsy surveillance protocols for the assessment of Barrett's esophagus can be subject to sampling errors, resulting in diagnostic uncertainty. Optical coherence tomography is a cross-sectional imaging technique that can be used to conduct volumetric laser endomicroscopy (VLE) of the entire distal esophagus. We have developed a biopsy guidance platform that places endoscopically visible marks at VLE-determined biopsy sites. Objective The objective of this study was to demonstrate in human participants the safety and feasibility of VLE-guided biopsy in vivo. Design A pilot feasibility study. Setting Massachusetts General Hospital. Patients A total of 22 participants were enrolled from January ...

      Read Full Article
    13. Fusion of optical coherence tomographic and angiographic data for more accurate evaluation of the endothelial shear stress patterns and neointimal distribution after bioresorbable scaffold implantation: comparison with intravascular ultrasound-derived rec

      Fusion of optical coherence tomographic and angiographic data for more accurate evaluation of the endothelial shear stress patterns and neointimal distribution after bioresorbable scaffold implantation: comparison with intravascular ultrasound-derived rec
      ...ravendijkwal 230, 3015 CE, Rotterdam, The Netherlands Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA Department of Cardiology, Medical School, University of Ioannina, Ioa...
      Read Full Article
    14. 1-15 of 429 1 2 3 4 ... 27 28 29 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources, Velocimetry
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Harvard University

    Harvard University

    Harvard University is a private university in Cambridge, Massachusetts, U.S. Founded in 1636 by the colonial Massachusetts legislature Harvard is the oldest institution of higher learning in the United States.  Harvard Medical School  is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts.  Schepens Eye Research Institute fights blindness by developing new technologies, therapies and knowledge to retain and restore vision. Through a continuum of discovery, the Institute works toward a future in which blindness is prevented, alleviated, and, ultimately, cured.