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    1. Mentioned In 883 Articles

    2. Effect of partial posterior vitreous detachment on spectral-domain optical coherence tomography retinal nerve fibre layer thickness measurements

      Effect of partial posterior vitreous detachment on spectral-domain optical coherence tomography retinal nerve fibre layer thickness measurements
      Background/aims To assess the effect of partial posterior vitreous detachment (pPVD) on spectral-domain optical coherence tomography (OCT) peripapillary retinal nerve fibre layer thickness (RNFL) measurements. Methods Spectral-domain OCT RNFL thickness measurements were obtained from 684 consecutive patients who were seen in the Massachusetts Eye and Ear Glaucoma Service. Of these patients, we compared RNFL thickness measurements between 101 eyes of 101 glaucoma suspects who met inclusion criteria (55 eyes ...
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    3. Artifact Rates for 2D Retinal Nerve Fiber Layer Thickness Versus 3D Retinal Nerve Fiber Layer Volume

      Artifact Rates for 2D Retinal Nerve Fiber Layer Thickness Versus 3D Retinal Nerve Fiber Layer Volume
      Purpose : To compare artifact rates in two-dimensional (2D) versus three-dimensional (3D) retinal nerve fiber layer (RNFL) scans using Spectralis optical coherence tomography (OCT) Methods : Thirteen artifact types in 2D and 3D RNFL scans were identified in 106 glaucomatous eyes and 95 normal eyes. Artifact rates were calculated per B-scan and per eye. In 3D volume scans, artifacts were counted only for the 97 B-scans used to calculate RNFL parameters for ...
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    4. Early versus delayed treatment with ticagrelor on residual thrombus after percutaneous coronary intervention in patients presenting with non-ST-elevation acute coronary syndrome: an optical coherence tomography study

      Early versus delayed treatment with ticagrelor on residual thrombus after percutaneous coronary intervention in patients presenting with non-ST-elevation acute coronary syndrome: an optical coherence tomography study
      Ticagrelor, a P2Y12 antagonist, is well known for its rapid, high-potent inhibition of platelet aggregation by pharmacokinetic studies [ 1 ]. In the PLATO study, ticagrelor, compared to clopidogrel, reduced the incidence of myocardial infarction, stroke, cardiovascular death and definite stent thrombosis, during 12-month follow-up in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) [ 2 , 3 ]. To date, the effect of early ticagrelor administration versus treatment at the time ...
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    5. Vectorial birefringence imaging by optical coherence microscopy for assessing fibrillar microstructures in the cornea and limbus

      Vectorial birefringence imaging by optical coherence microscopy for assessing fibrillar microstructures in the cornea and limbus
      The organization of fibrillar tissue on the micrometer scale carries direct implications for health and disease but remains difficult to assess in vivo . Polarization-sensitive optical coherence tomography measures birefringence, which relates to the microscopic arrangement of fibrillar tissue components. Here, we demonstrate a critical improvement in leveraging this contrast mechanism by employing the improved spatial resolution of focus-extended optical coherence microscopy (1.4 m axially in air and 1.6 ...
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    6. Resolving absolute depth in circular-ranging optical coherence tomography by using a degenerate frequency comb

      Resolving absolute depth in circular-ranging optical coherence tomography by using a degenerate frequency comb
      In Fourier-domain optical coherence tomography, an interference signal is generated that spans an RF bandwidth proportional to the product of three parameters: the imaging range, the imaging speed, and the inverse of the axial resolution. Circular-ranging optical coherence tomography (CR-OCT) architectures were introduced to ease long-range imaging by decoupling the imaging range from the signal RF bandwidth. As a consequence, present CR-OCT systems resolve the relative, but not the absolute ...
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    7. Massachusetts General Hospital Receives NIH Grant for Unique Value of Real-Time Shear Stress To Enhance Coronary Disease Management

      Massachusetts General Hospital Receives NIH Grant for Unique Value of Real-Time Shear Stress To Enhance Coronary Disease Management
      Massachusetts General Hospital Receives a 2020 NIH Grant for $771,279 for Unique Value of Real-Time Shear Stress To Enhance Coronary Disease Management. The principal investigator is Guillermo Tearney. Below is a summary of the proposed work. Management of CAD is hindered by our inability to investigate fundamental pathobiologic processes that lead to individual coronary plaque progression, destabilization, and adverse clinical events. A critical mechanism responsible for plaque behavior is ...
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    8. Massachusetts General Hospital Receives NIH Grant for A Tethered Capsule Endoscopic-Endomicroscopic (TEEM) Approach for Improving Upper GI Tract Diagnosis

      Massachusetts General Hospital Receives NIH Grant for A Tethered Capsule Endoscopic-Endomicroscopic (TEEM) Approach for Improving Upper GI Tract Diagnosis
      Massachusetts General Hospital Receives a 2020 NIH Grant for $627,739 for A Tethered Capsule Endoscopic-Endomicroscopic (TEEM) Approach for Improving Upper GI Tract Diagnosis. The principal investigator is Guillermo Tearney. Below is a summary of the proposed work. The diagnosis of most upper GI tract conditions is currently accomplished by upper endoscopy with biopsy (EGD). EGD is costly primarily because it requires conscious sedation, necessitating that procedures be conducted by ...
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    9. Beth Israel Deaconess Medical Center Receives NIH Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology

      Beth Israel Deaconess Medical Center Receives NIH Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology
      ...uctor in Medicine at Harvard Medical School, Boston, Massachusetts. He is a graduate of the MD-PhD program at Harvard Medical School and Massachusetts Institute of Technology, and has completed clinical training in medic...
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    10. Early versus delayed treatment with ticagrelor on residual thrombus after percutaneous coronary intervention in patients presenting with non-ST-elevation acute coronary syndrome an optical coherence tomography study

      Early versus delayed treatment with ticagrelor on residual thrombus after percutaneous coronary intervention in patients presenting with non-ST-elevation acute coronary syndrome an optical coherence tomography study
      Objective The level of inhibition of platelet aggregation immediately before percutaneous coronary intervention (PCI) is known to be related to early periprocedural outcomes. Ticagrelor is a reversible P2Y12 inhibitor that provides faster and more effective platelet inhibition compared to clopidogrel. This study sought to compare the antiplatelet effect on residual thrombus between early vs. delayed administration of ticagrelor following PCI in patients presenting with non-ST-elevation acute coronary syndromes (NSTE-ACS). Methods ...
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    11. Characteristics of non-culprit plaques in acute coronary syndrome patients with layered culprit plaque

      Characteristics of non-culprit plaques in acute coronary syndrome patients with layered culprit plaque
      Aims Layered plaques represent signs of previous plaque destabilization. A recent study showed that acute coronary syndrome (ACS) patients with layered culprit plaque have more vulnerability at the culprit lesion and systemic inflammation. We aimed to compare the characteristics of non-culprit plaques between patients with or without layered plaque at the culprit lesion. We also evaluated the characteristics of layered non-culprit plaques, irrespective of culprit plaque phenotype. Methods and results ...
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    12. All fiber polarization insensitive detection for spectrometer based optical coherence tomography using optical switch

      All fiber polarization insensitive detection for spectrometer based optical coherence tomography using optical switch
      Polarization dependent image artifacts are common in optical coherence tomography imaging. Polarization insensitive detection scheme for swept source based optical coherence tomography systems is well established but is yet to be demonstrated for all fiber spectrometer-based Fourier domain optical coherence tomography systems. In this work, we present an all fiber polarization insensitive detection scheme for spectrometer based optical coherence tomography systems. Images from chicken breast muscle tissue were acquired to ...
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    13. Stable multi-megahertz circular-ranging optical coherence tomography at 1.3 µm

      Stable multi-megahertz circular-ranging optical coherence tomography at 1.3 µm
      In Fourier-domain optical coherence tomography (OCT), the finite bandwidth of the acquisition electronics constrains the depth range and speed of the system. Circular-ranging (CR) OCT methods use optical-domain compression to surpass this limit. However, the CR-OCT system architectures of prior reports were limited by poor stability and were confined to the 1.55 m wavelength range. In this work, we describe a novel CR-OCT architecture that is free from these ...
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    14. Postdoctoral Research Fellowships (In Vivo Microscopy) at the Massachusetts General Hospital

      Postdoctoral Research Fellowships (In Vivo Microscopy) at the Massachusetts General Hospital
      ...de at the rank of postdoctoral fellow at Harvard Medical School. MGHs role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for dev...
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    15. Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hospital

      Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hospital
      ...ard Medical School, commensurate with the applicants experience. MGHs role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for dev...
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    16. 1-15 of 883 1 2 3 4 ... 57 58 59 »
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  2. About Harvard University

    Harvard University

    Harvard University is a private university in Cambridge, Massachusetts, U.S. Founded in 1636 by the colonial Massachusetts legislature Harvard is the oldest institution of higher learning in the United States.  Harvard Medical School  is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts.  Schepens Eye Research Institute fights blindness by developing new technologies, therapies and knowledge to retain and restore vision. Through a continuum of discovery, the Institute works toward a future in which blindness is prevented, alleviated, and, ultimately, cured.