1. Harvard University

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    1. Mentioned In 1050 Articles

    2. In Vivo Three-Dimensional Imaging of Neovascular Age-Related Macular Degeneration Using Optical Frequency Domain Imaging at 1050 nm

      ...ital and Harvard Medical School, Boston, Massachusetts; and the^ ^^3Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts. ^ PURPOSE. To assess the application of optical frequency domai...
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    3. Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands

      Apparatus, method, logic arrangement and storage medium are provided for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry ("LCI") signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies. The LCI broad bandwidth source can be split into N spectral bands. The N spectral bands can be individually detected and processed to provide an increase in ...
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    4. Ultrasound-enhanced optical coherence tomography: improved penetration and resolution

      Ultrasound-enhanced optical coherence tomography: improved penetration and resolution
      Chuanyong Huang, Bin Liu, Mark E. Brezinski Increasing penetration remains one of the most important issues in optical coherence tomography (OCT) research, which we achieved with a parallel ultrasound beam. In addition to qualitative improvements of tissue imaging, quantitative improvements in resolution of up to 28%±2% was noted. At ... [J. Opt. Soc. Am. A 25, 938-946 (2008)]
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    5. Monitoring mouse retinal degeneration with high-resolution spectral-domain optical coherence tomography.

      Related Articles Monitoring mouse retinal degeneration with high-resolution spectral-domain optical coherence tomography. J Vis. 2008;8(1):17.1-11 Authors: Kim KH, Puoris'haag M, Maguluri GN, Umino Y, Cusato K, Barlow RB, de Boer JF Progression of retinal degeneration in a mouse model was studied in vivo with high-resolution spectral-domain optical coherence tomography (SD-OCT). Imaging in 3D with high depth resolution ( PMID: 18318620 [PubMed - in process]
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    6. In Vivo Comparison of Optical Coherence Tomography and Angioscopy for the Evaluation of Coronary Plaque Characteristics

      Atherosclerotic yellow plaques identified by coronary angioscopy are considered as vulnerable plaques. However, characteristics of yellow plaques are not well understood. Optical coherence tomography (OCT) provides accurate tissue characterization in vivo and has the capability to measure fibrous cap thickness covering a lipid plaque. Characteristics of yellow plaques identified by angioscopy were evaluated by OCT. We examined 205 plaques of 41 coronary arteries in 26 patients. In OCT analysis, plaques ...
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    7. Spectral-domain optical coherence phase microscopy for quantitative biological studies (Thesis)

      Spectral-domain optical coherence phase microscopy for quantitative biological studies (Thesis)
      Conventional phase-contrast and differential interference contrast microscopy produce high contrast images of transparent specimens such as cells. However, they do not provide quantitative information or do not have enough sensitivity to detect nanometerlevel structural alterations. We have developed spectral-domain optical coherence phase microscopy (SD-OCPM) for highly sensitive quantitative phase imaging in 3D. This technique employs common-path spectral-domain optical coherence reflectometry to produce depth-resolved reflectance and quantitative phase images with high ...
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  2. About Harvard University

    Harvard University

    Harvard University is a private university in Cambridge, Massachusetts, U.S. Founded in 1636 by the colonial Massachusetts legislature Harvard is the oldest institution of higher learning in the United States.  Harvard Medical School  is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts.  Schepens Eye Research Institute fights blindness by developing new technologies, therapies and knowledge to retain and restore vision. Through a continuum of discovery, the Institute works toward a future in which blindness is prevented, alleviated, and, ultimately, cured.