1. Harvard University

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    1. Mentioned In 816 Articles

    2. Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra A-line polarization modulation

      We demonstrate a novel high-speed polarization-sensitive optical frequency domain imaging system employing high-speed polarization modulation. Rapid and continuous polarization modulation of light prior to illumination of the sample is accomplished by shifting the frequency of one polarization ... [Opt. Lett. 33, 1330-1332 (2008)]
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    3. Fiber-optic rotational device, optical system and method for imaging a sample

      A device, system and method for transmitting electro-magnetic radiation between at least two separate fibers (as well as for imaging a sample) are provided. For example, a first optical fiber and a second optical fiber may be provided, such that the first and/or second fibers is/are rotatable. At least one first optical arrangement may also be included which communicates with at least one end of the first optical ...
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    4. Association of statin therapy with reduced coronary plaque rupture: an optical coherence tomography study.

      Coronary Artery Disease. 19(4):237-242, June 2008. Chia, Stanley a; Raffel, Owen Christopher a; Takano, Masamichi c; Tearney, Guillermo J. b; Bouma, Brett E. b; Jang, Ik-Kyung a Abstract: Objective: Statin therapy induces plaque regression and may stabilize atheromatous plaques. Optical coherence tomography (OCT) is a high-resolution in-vivo imaging modality that allows characterization of atherosclerotic plaques. We aimed to demonstrate the potential utility of OCT in evaluating coronary plaque
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    5. System and method for optical coherence imaging

      A system and method for imaging of a sample, e.g., biological sample, are provided. In particular, at least one source electro-magnetic radiation forwarded to the sample and a reference may be generated. A plurality of detectors may be used, at least one of the detectors capable of detecting a signal associated with a combination of at least one first electro-magnetic radiation received from the sample and at least one ...
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    6. System and method for optical coherence imaging

      Apparatus and method are provided for transmitting at least one electro-magnetic radiation is provided. In particular, at least one optical fiber having at least one end extending along a first axis may be provided. Further, a light transmissive optical arrangement may be provided in optical cooperation with the optical fiber. The optical arrangement may have a first surface having a portion that is perpendicular to a second axis, and a ...
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    7. In Vivo Three-Dimensional Imaging of Neovascular Age-Related Macular Degeneration Using Optical Frequency Domain Imaging at 1050 nm

      ...ital and Harvard Medical School, Boston, Massachusetts; and the^ ^^3Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts. ^ PURPOSE. To assess the application of optical frequency domai...
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    8. Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands

      Apparatus, method, logic arrangement and storage medium are provided for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry ("LCI") signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies. The LCI broad bandwidth source can be split into N spectral bands. The N spectral bands can be individually detected and processed to provide an increase in ...
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    9. Ultrasound-enhanced optical coherence tomography: improved penetration and resolution

      Ultrasound-enhanced optical coherence tomography: improved penetration and resolution
      Chuanyong Huang, Bin Liu, Mark E. Brezinski Increasing penetration remains one of the most important issues in optical coherence tomography (OCT) research, which we achieved with a parallel ultrasound beam. In addition to qualitative improvements of tissue imaging, quantitative improvements in resolution of up to 28%±2% was noted. At ... [J. Opt. Soc. Am. A 25, 938-946 (2008)]
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  2. About Harvard University

    Harvard University

    Harvard University is a private university in Cambridge, Massachusetts, U.S. Founded in 1636 by the colonial Massachusetts legislature Harvard is the oldest institution of higher learning in the United States.  Harvard Medical School  is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts.  Schepens Eye Research Institute fights blindness by developing new technologies, therapies and knowledge to retain and restore vision. Through a continuum of discovery, the Institute works toward a future in which blindness is prevented, alleviated, and, ultimately, cured.