1. Harvard University

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    1. Mentioned In 491 Articles

    2. Postdoctoral Research Fellowships (Optical Coherence Tomography) Wellman Center for Photomedicine Massachusetts General Hospital

      Postdoctoral Research Fellowships (Optical Coherence Tomography) Wellman Center for Photomedicine Massachusetts General Hospital
      ...de at the rank of postdoctoral fellow at Harvard Medical School. MGHs role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for dev...
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    3. Infraredx Announces Research Collaboration with Massachusetts General Hospital to Explore New Generation of Cardiovascular Imaging Devices

      Infraredx Announces Research Collaboration with Massachusetts General Hospital to Explore New Generation of Cardiovascular Imaging Devices
      ... Hospital (MGH) and leading coronary imaging researcher, Gary Tearney, M.D., Ph.D., professor of pathology at Harvard Medical School, Mike and Sue Hazard Family MGH Research Scholar, and founder of the Tearney Lab at the...
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    4. Patient Characteristics Associated with Artifacts in Spectralis Optical Coherence Tomography Imaging of the Retinal Nerve Fiber Layer in Glaucoma

      Patient Characteristics Associated with Artifacts in Spectralis Optical Coherence Tomography Imaging of the Retinal Nerve Fiber Layer in Glaucoma
      ...School, Boston, MA , BA , Huseyin Simavli x Huseyin Simavli Search for articles by this author Affiliations * Harvard Medical School, Boston, MA * Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston,...
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    5. Hand scanning optical coherence tomography imaging using encoder feedback

      Hand scanning optical coherence tomography imaging using encoder feedback

      We present a new method for generating micron-scale OCT images of interstitial tissue with a hand scanning probe and a linear optical encoder that senses probe movement relative to a fixed reference point, i.e., tissue surface. Based on this approach, we demonstrate high resolution optical imaging of biological tissues through a very long biopsy needle. Minor artifacts caused by tissue noncompliance are corrected using a software algorithm which detects the simple repetition of the adjacent A-scans. This hand-scanning OCT imaging approach offers the physician the freedom to access imaging sites of interest repeatedly.

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    6. Ultrahigh speed endoscopic optical coherence tomography for gastroenterology

      Ultrahigh speed endoscopic optical coherence tomography for gastroenterology

      We describe an ultrahigh speed endoscopic swept source optical coherence tomography (OCT) system for clinical gastroenterology using a vertical-cavity surface-emitting laser (VCSEL) and micromotor imaging catheter. The system had a 600 kHz axial scan rate and 8 µm axial resolution in tissue. Imaging was performed with a 3.2 mm diameter imaging catheter at 400 frames per second with a 12 µm spot size. Three-dimensional OCT (3D-OCT) imaging was performed in patients with a cross section of pathologies undergoing upper and lower endoscopy. The use of distally actuated imaging catheters enabled OCT imaging with more flexibility, such as volumetric imaging ...

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    7. Low coherence interferometry approach for aiding fine needle aspiration biopsie

      Low coherence interferometry approach for aiding fine needle aspiration biopsie

      We present portable preclinical low-coherence interference (LCI) instrumentation for aiding fine needle aspiration biopsies featuring the second-generation LCI-based biopsy probe and an improved scoring algorithm for tissue differentiation. Our instrument and algorithm were tested on 38 mice with cultured tumor mass and we show the specificity, sensitivity, and positive predictive value of tumor detection of over 0.89, 0.88, and 0.96, respectively.

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    8. Are the findings of optical coherence tomography sufficient for the evaluation of the safety and efficacy of the next generation of drug eluting stents

      Are the findings of optical coherence tomography sufficient for the evaluation of the safety and efficacy of the next generation of drug eluting stents

      The cr8 stent is a next generation drug eluting stent (DES) with a polymer free abluminal reservoir drug release system. It uses an organic fatty acid permeation enhancer and a carbon surface to increase biocompatibility. The fatty acid enhancer may have beneficial effect in improving drug delivery in diabetic patient where neointimal hyperplasia is particularly problematic[1]. These types of design features are exciting new developments and may provide novel strategies for improving the safety and efficacy of the next generation of coronary stents.

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    9. Insights into the spatial distribution of lipid-rich plaques in relation to coronary artery bifurcations: an in-vivo optical coherence tomography study

      Insights into the spatial distribution of lipid-rich plaques in relation to coronary artery bifurcations: an in-vivo optical coherence tomography study

      Objectives: The aim of this study was to investigate the spatial location of vulnerable plaques at coronary artery bifurcations using frequency domain-optical coherence tomography. Background: In-vivo data on geometric location of vulnerable plaques in relation to coronary bifurcation are limited. Materials and methods: A total of 40 patients with left anterior descending artery bifurcation were studied. Plaque characteristics in five regions in relation to a side branch were compared: opposite flow divider (OFD); bifurcation site (BF); main branch side proximal (MBP); side branch side proximal (SBP); and flow divider (FD). Frequency domain-optical coherence tomography was used for plaque characterization. Results ...

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    10. Dual modality intravascular optical coherence tomography (OCT) and near-infrared fluorescence (NIRF) imaging: a fully automated algorithm for the distance-calibration of NIRF signal intensity for quantitative molecular imaging

      Dual modality intravascular optical coherence tomography (OCT) and near-infrared fluorescence (NIRF) imaging: a fully automated algorithm for the distance-calibration of NIRF signal intensity for quantitative molecular imaging
      ..., MA, USA Department of Pathology, Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA Harvard-Massachusetts Institute of Technology Health Sciences and Technology, Cambridge, MA, USA ...
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    11. All-fiber wavelength swept ring laser based on Fabry-Perot filter for optical frequency domain imaging

      All-fiber wavelength swept ring laser based on  Fabry-Perot filter for optical frequency domain  imaging
      ...g-Yuhl Oh,^2 and Brett E. Bouma^1,^3 ^1Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA ^2Department of Mechanical Engineering, KAIST, 291 ...
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    12. Longitudinal necrotic shafts near TCFAs—A potential novel mechanism for plaque rupture to trigger ACS?

      Longitudinal necrotic shafts near TCFAs—A potential novel mechanism for plaque rupture to trigger ACS?
      ...ter for Optics and Modern Physics, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA * Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA * Department of Electrical Engineering, ...
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    13. 1-15 of 491 1 2 3 4 ... 31 32 33 »
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  2. About Harvard University

    Harvard University

    Harvard University is a private university in Cambridge, Massachusetts, U.S. Founded in 1636 by the colonial Massachusetts legislature Harvard is the oldest institution of higher learning in the United States.  Harvard Medical School  is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts.  Schepens Eye Research Institute fights blindness by developing new technologies, therapies and knowledge to retain and restore vision. Through a continuum of discovery, the Institute works toward a future in which blindness is prevented, alleviated, and, ultimately, cured.