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    1. Mentioned In 625 Articles

    2. Free-Floating Pigmented Vitreous Cyst: Optical Coherence Tomography Findings

      Free-Floating Pigmented Vitreous Cyst: Optical Coherence Tomography Findings
      A 54-year-old woman presented with a chronic floater in the right eye. Dilated fundus examination revealed a pigmented free-floating vitreous cyst (Fig 1 A , Optos, Marlborough, MA). Saccades caused quick and fluid movements of the mobile sphere. Spectral-domain optical coherence tomography (SD OCT) (Fig 1 B , Spectralis; Heidelberg, Heidelberg, Germany) demonstrated a round, hyperreflective shell with hyporeflective contents. The lesion is anterior to the upper limit of the OCT and ...
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    3. Velocity gradients in spatially resolved laser Doppler flowmetry and dynamic light scattering with confocal and coherence gating

      Velocity gradients in spatially resolved laser Doppler flowmetry and dynamic light scattering with confocal and coherence gating
      Dynamic light scattering (DLS) is widely used to characterize diffusive motion to obtain precise information on colloidal suspensions by calculating the autocorrelation function of the signal from a heterodyne optical system. DLS can also be used to determine the flow velocity field in systems that exhibit mass transport by incorporating the effects of the deterministic motion of scatterers on the autocorrelation function, a technique commonly known as laser Doppler flowmetry ...
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    4. Astigmatism corrected common path probe for optical coherence tomography

      Astigmatism corrected common path probe for optical coherence tomography
      Background and Objectives Optical coherence tomography (OCT) catheters for intraluminal imaging are subject to various artifacts due to reference-sample arm dispersion imbalances and sample arm beam astigmatism. The goal of this work was to develop a probe that minimizes such artifacts. Materials and Methods Our probe was fabricated using a single mode fiber at the tip of which a glass spacer and graded index objective lens were spliced to achieve ...
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    5. Postdoctoral Research Fellowships in In Vivo Microscopy at Wellman Center for Photomedicine, Massachusetts General Hospital

      Postdoctoral Research Fellowships in In Vivo Microscopy at Wellman Center for Photomedicine,  Massachusetts General Hospital
      ...de at the rank of postdoctoral fellow at Harvard Medical School. MGHs role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for dev...
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    6. Brigham and Women's Hospital Receives a NIH Grant for Aortic Valve Microcalicifacation

      Brigham and Women's Hospital Receives a NIH Grant for Aortic Valve Microcalicifacation
      Brigham and Women's Hospital Receives a 2016 NIH Grant for $415,740 for Aortic Valve Microcalicifacation. The principal investigator is Elena Aikawa. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. This research project will test the hypothesis that, in the diabetic milieu, S100A9 induces the calcification potential of valvular interstitial cell (VIC)-derived matrix vesicles, precursors of microcalcification, offering the ...
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    7. The new kid on the block for advanced imaging in Barrett’s esophagus: a review of volumetric laser endomicroscopy

      The new kid on the block for advanced imaging in Barrett’s esophagus: a review of volumetric laser endomicroscopy
      Advanced imaging techniques used in the management of Barretts esophagus include electronic imaging enhancement (e.g. narrow band imaging, flexible spectral imaging color enhancement, and i-Scan), chromoendoscopy, and confocal laser endomicroscopy. Electronic imaging enhancement is used frequently in daily practice, but use of the other advanced technologies is not routine. High-definition white light endoscopy and random four quadrant biopsy remain the standard of care for evaluation of Barretts esophagus; this ...
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    8. Spectral-Domain Optical Coherence Tomography, Wide-Field Photography, and Fundus Autofluorescence Correlation of Posterior Ophthalmomyiasis Interna

      Spectral-Domain Optical Coherence Tomography, Wide-Field Photography, and Fundus Autofluorescence Correlation of Posterior Ophthalmomyiasis Interna
      Posterior ophthalmomyiasis interna is a rare, potentially devastating infestation of the posterior segment by fly larvae. The authors report the first demonstration of spectral-domain optical coherence tomography (SD-OCT) (Spectralis; Heidelberg Engineering, Heidelberg, Germany), wide-field angiography (Optos, Dunfermline, Scotland) and photography, and fundus autofluorescence with temporal progression during a period of 6 months. A 12-year-old white female presented with acute, painless vision loss with hand motions visual acuity. No larva was ...
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    9. Drs. Campbell, Hariri, and Lehman Receive 2016 LUNGevity Career Development Awards

      Drs. Campbell, Hariri, and Lehman Receive 2016 LUNGevity Career Development Awards
      Lida Hariri , MD, Massachusetts General Hospital, who will use a novel high-resolution imaging technique called Optical Coherence Tomography to perform virtual optical biopsies to determine its value in complementing tissue biopsies in the determination of early-stage lung cancer
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    10. Diagnosis of Thin-Capped Fibroatheromas in Intravascular Optical Coherence Tomography Images Effects of Light Scattering

      Diagnosis of Thin-Capped Fibroatheromas in Intravascular Optical Coherence Tomography Images Effects of Light Scattering
      Background Intravascular optical coherence tomography (IVOCT) images are recorded by detecting light backscattered within coronary arteries. We hypothesize that nonthin-capped fibroatheroma (TCFA) causes may scatter light to create the false appearance of IVOCT TCFA. Methods and Results Ten human cadaver hearts were imaged with IVOCT (n=14 coronary arteries). IVOCT and histological TCFA images were coregistered and compared. Of 21 IVOCT TCFAs (fibrous cap 65 m, lipid arc 1 quadrant ...
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    11. The Pattern of Visual Fixation Eccentricity and Instability in Optic Neuropathy and Its Spatial Relationship to Retinal Ganglion Cell Layer Thickness

      The Pattern of Visual Fixation Eccentricity and Instability in Optic Neuropathy and Its Spatial Relationship to Retinal Ganglion Cell Layer Thickness
      Purpose : The purpose of this study was to assess whether clinically useful measures of fixation instability and eccentricity can be derived from retinal tracking data obtained during optical coherence tomography (OCT) in patients with optic neuropathy (ON) and to develop a method for relating fixation to the retinal ganglion cell complex (GCC) thickness. Methods : Twenty-nine patients with ON underwent macular volume OCT with 30 seconds of confocal scanning laser ophthalmoscope ...
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    12. Massachusetts General Hospital Receives a 2016 NIH Grant for Celiac Disease Diagnosis Using Tethered Capsule Endomicroscopy

      Massachusetts General Hospital Receives a 2016 NIH Grant for Celiac Disease Diagnosis Using Tethered Capsule Endomicroscopy
      Massachusetts General Hospital Receives a 2016 NIH Grant for $573,805 for Celiac Disease Diagnosis Using Tethered Capsule Endomicroscopy. The principal investigator is Guillermo Tearney. The program began in $2014 and ends in 2019. Below is a summary of the proposed work. Celiac disease (CD) is an autoimmune response to gluten proteins that affects 3M people in the US and 50M worldwide. These proteins incite an inflammatory reaction that eventually ...
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    13. In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography

      In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography
      Direct in vivo imaging of lymph flow is key to understanding lymphatic system function in normal and disease states. Optical microscopy techniques provide the resolution required for these measurements, but existing optical techniques for measuring lymph flow require complex protocols and provide limited temporal resolution. Here, we describe a Doppler optical coherence tomography platform that allows direct, label-free quantification of lymph velocity and volumetric flow rates. We overcome the challenge ...
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    14. Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter

      Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter
      We demonstrate a micromotor balloon imaging catheter for ultrahigh speed endoscopic optical coherence tomography (OCT) which provides wide area, circumferential structural and angiographic imaging of the esophagus without contrast agents. Using a 1310 nm MEMS tunable wavelength swept VCSEL light source, the system has a 1.2 MHz A-scan rate and ~8.5 m axial resolution in tissue. The micromotor balloon catheter enables circumferential imaging of the esophagus at 240 ...
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    15. Massachusetts General Hospital Receives NIH Grant for the Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives NIH Grant for the Center for Biomedical OCT Research and Translation
      Massachusetts General Hospital Receives a 2016 NIH Grant for $1,460,266 for the Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2021. Below is a summary of the propose work. Overall the Center for Biomedical OCT Research and Translation seeks to push the technological frontier of optical coherence tomography instrumentation and methods in response to challenges ...
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    16. 1-15 of 625 1 2 3 4 ... 40 41 42 »
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  2. About Harvard University

    Harvard University

    Harvard University is a private university in Cambridge, Massachusetts, U.S. Founded in 1636 by the colonial Massachusetts legislature Harvard is the oldest institution of higher learning in the United States.  Harvard Medical School  is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts.  Schepens Eye Research Institute fights blindness by developing new technologies, therapies and knowledge to retain and restore vision. Through a continuum of discovery, the Institute works toward a future in which blindness is prevented, alleviated, and, ultimately, cured.