1. Harbin Medical University

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    1. Mentioned In 141 Articles

    2. Automatic assessment of calcified plaque and nodule by optical coherence tomography adopting deep learning model

      Automatic assessment of calcified plaque and nodule by optical coherence tomography adopting deep learning model
      Optical coherence tomography (OCT) has become the best imaging tool to assess calcified plaque and nodule. However, every OCT pullback has numerous images, and artificial analysis requires too much time and energy. Thus, it is unsuitable for clinical application. This study aimed to develop and validate an automatic assessment of calcified plaque and nodule by OCT using deep-learning model. The OCT images of calcified plaque and nodule were labeled by ...
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    3. Risk Stratification in Acute Coronary Syndrome by Comprehensive Morphofunctional Assessment With Optical Coherence Tomography

      Risk Stratification in Acute Coronary Syndrome by Comprehensive Morphofunctional Assessment With Optical Coherence Tomography
      Background: Artificial intelligence enables simultaneous evaluation of plaque morphology and computational physiology from optical coherence tomography (OCT). Objectives: This study sought to appraise the predictive value of major adverse cardiovascular events (MACE) by combined plaque morphology and computational physiology. Methods: A total of 604 patients with acute coronary syndrome who underwent OCT imaging in 1 nonculprit vessel during index coronary angiography were retrospectively enrolled. A novel morphologic index, named the ...
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    4. Feasibility and Safety of Hybrid IVUS-OCT System

      Feasibility and Safety of Hybrid IVUS-OCT System
      Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) were all recommended for percutaneous coronary intervention (PCI) optimization in the latest guidelines, however, which imaging modality was more suitable as either a diagnostic or guidance tool was still unknown. Recently, a novel, well-designed hybrid imaging system was approved for clinical use, allowing the accurate co-registration of two imaging modalities and immediate, simultaneous image review. For testing each modality in the hybrid ...
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    5. Effects of intermittent cold-exposure on culprit plaque morphology in ST-segment elevation myocardial infarction patients: a retrospective study based on optical coherence tomography

      Effects of intermittent cold-exposure on culprit plaque morphology in ST-segment elevation myocardial infarction patients: a retrospective study based on optical coherence tomography
      Objective: Present study aimed to explore the effects of intermittent cold-exposure (ICE) on culprit plaque morphology in patients with ST- segment elevation myocardial infarction (STEMI) in frigid zone. Methods: Totally 848 STEMI patients with plaque rupture ( N = 637) or plaque erosion ( N = 211) were enrolled consecutively according to optical coherence tomography imaging. Data on the changes of outdoor air temperature corresponding to 24 solar terms were collected. Patients were divided ...
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    6. Image enhancement of wide-field retinal optical coherence tomography angiography by super-resolution angiogram reconstruction generative adversarial network

      Image enhancement of wide-field retinal optical coherence tomography angiography by super-resolution angiogram reconstruction generative adversarial network
      Wide-field retinal optical coherence tomography angiography (OCTA) usually suffers from low image resolution in clinical practice because of insufficient lateral sampling. In this study, we develop a deep-learning-based method named super-resolution angiogram reconstruction generative adversarial network (SAR-GAN) to enhance the en face OCTA image quality. A sophisticated home-made spectral-domain OCTA system is employed to capture the data of retinal angiograms with different scanning protocols. High-resolution 3 3 mm 2 OCTA ...
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    7. Clinical Outcomes of Different Calcified Culprit Plaques in Patients with Acute Coronary Syndrome

      Clinical Outcomes of Different Calcified Culprit Plaques in Patients with Acute Coronary Syndrome
      Background: Previous studies have found that coronary artery calcification is closely associated with the occurrence of major adverse cardiac events (MACE). This study aimed to investigate the characteristics and clinical outcomes of different calcified plaques in patients with acute coronary syndrome (ACS) by using optical coherence tomography (OCT). Methods: 258 ACS patients with calcified culprit plaques who underwent OCT-guided stent implantation were enrolled. They were divided into three subtypes based ...
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    8. Association Between Dietary Intakes and Plaque Vulnerability Measured by Optical Coherence Tomography in Patients With Coronary Heart Disease: A Mediation Analysis of Inflammatory Factors

      Association Between Dietary Intakes and Plaque Vulnerability Measured by Optical Coherence Tomography in Patients With Coronary Heart Disease: A Mediation Analysis of Inflammatory Factors
      Although studies have proven that diet has a critical role in preventing or delaying atherosclerosis and is far simpler to adjust and adhere to than other risk factors, the underlying mechanisms behind this effect remain not well comprehended. The purpose of this investigation was to determine the impact of inflammatory factors on the connection between dietary ingestion and coronary plaque fragility as measured via optical coherence tomography (OCT) in patients ...
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    9. Cholesterol crystals in non-culprit plaques of STEMI patients: A 3-vessel OCT study

      Cholesterol crystals in non-culprit plaques of STEMI patients: A 3-vessel OCT study
      Background: Cholesterol crystals (CCs) are regular microstructures found within the necrotic core of atherosclerotic plaques and have been hypothesized to be related to plaque destabilization. We attempted to investigate the potential association between CCs and non-culprit plaque vulnerability in patients with ST-segment elevated myocardial infarction (STEMI) and study morphological features of CCs in ruptured non-culprit plaques. Methods: A total of 261 patients with ST-segment elevation myocardial infarction who underwent 3-vessel ...
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    10. In vivo detection of plaque erosion by intravascular optical coherence tomography using artificial intelligence

      In vivo detection of plaque erosion by intravascular optical coherence tomography using artificial intelligence
      Plaque erosion is one of the most common underlying mechanisms for acute coronary syndrome (ACS). Optical coherence tomography (OCT) allows in vivo diagnosis of plaque erosion. However, challenge remains due to high inter- and intra-observer variability. We developed an artificial intelligence method based on deep learning for fully automated detection of plaque erosion in vivo , which achieved a recall of 0.8000.175, a precision of 0.7340.254, and ...
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    11. Optical coherence tomography in coronary atherosclerosis assessment and intervention

      Optical coherence tomography in coronary atherosclerosis assessment and intervention
      Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in ...
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    12. Feasibility and Safety of Very-Low Contrast Combined Ringer's Solution in Optical Coherence Tomography Imaging

      Feasibility and Safety of Very-Low Contrast Combined Ringer's Solution in Optical Coherence Tomography Imaging
      Background: Optical coherence tomography (OCT) is an important modality used in coronary intervention. However, OCT requires a high amount of contrast media, limiting its extensive application in clinical practice. This study compared OCT images of coronary lesions obtained using contrast media and very-low contrast combined Ringer's solution (VLCCR) in patients with acute coronary syndrome (ACS). Methods: Thirty ACS patients with a total of 36 native lesions and stenoses from ...
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    13. A Multicenter RCT of OCT-Guided Reperfusion in STEMI With Early Infarct Artery Patency

      A Multicenter RCT of OCT-Guided Reperfusion in STEMI With Early Infarct Artery Patency
      Objectives The aim of this study was to test whether optical coherence tomographic (OCT) guidance would provide additional useful information beyond that obtained by angiography and lead to a shift in reperfusion strategy and improved clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) with early infarct artery patency. Background Angiography is limited in assessing the underlying pathophysiological mechanisms of the culprit lesion. Methods EROSION III (Optical Coherence TomographyGuided ...
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    14. The potential mediating effects of inflammation on the association between Type D personality and coronary plaque vulnerability in patients with coronary artery disease: An optical coherence tomography study

      The potential mediating effects of inflammation on the association between Type D personality and coronary plaque vulnerability in patients with coronary artery disease: An optical coherence tomography study
      Objective: Type D personality involves the interaction between negative affectivity with social inhibition and has been associated with an increased risk of coronary artery disease (CAD) progression and coronary plaque vulnerability. However, the underlying mechanisms in the relationship between Type D personality and coronary plaque vulnerability remain indeterminate. The present study examined the potential mediating effects of inflammation biomarkers on the association between Type D personality and coronary plaque vulnerability ...
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    15. Artificial Intelligence—A Good Assistant to Multi-Modality Imaging in Managing Acute Coronary Syndrome

      Artificial Intelligence—A Good Assistant to Multi-Modality Imaging in Managing Acute Coronary Syndrome
      Acute coronary syndrome is the leading cause of cardiac death and has a significant impact on patient prognosis. Early identification and proper management are key to ensuring better outcomes and have improved significantly with the development of various cardiovascular imaging modalities. Recently, the use of artificial intelligence as a method of enhancing the capability of cardiovascular imaging has grown. AI can inform the decision-making process, as it enables existing modalities ...
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  2. About Harbin Medical University

    Harbin Medical University

    Harbin Medical University is a public university located in Harbin, Heilongjiang , China . It was established in 1926 as Harbin Medical College. It was renamed to University in 1958.  Harbin, a beautiful city well-known for its ice and snow  and reputed as “Eastern Paris”. HMU has a  scenic view on the campus dotted with ancient-style buildings, with a total  area of 2.36 million square meters.