1. Harbin Medical University

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    1. Mentioned In 110 Articles

    2. Cascade Faster R-CNN Detection for Vulnerable Plaques in OCT Images

      Cascade Faster R-CNN Detection for Vulnerable Plaques in OCT Images
      Through the application of optical coherence tomography (OCT), computerized medical image analysis can provide intelligent, auxiliary diagnosis for patients with atherosclerosis. In order to provide higher-resolution imaging for medical interventions, a novel deformable cascade faster region-based convolutional neural networks (Faster R-CNN) is proposed to realize vascular plaque recognition in OCT images. The cascade convolutional network is designed for lumen feature detection, and the deformable convolution and region of interest pooling ...
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    3. Automatic Characterisation of Human Atherosclerotic Plaque Composition from Intravascular Optical Coherence Tomography Using Artificial Intelligence

      Automatic Characterisation of Human Atherosclerotic Plaque Composition from Intravascular Optical Coherence Tomography Using Artificial Intelligence
      Background Intravascular optical coherence tomography (IVOCT) enables detailed plaque characterisation in-vivo, but visual assessment is time-consuming and subjective. Aims This study aims to develop and validate an automatic framework for IVOCT plaque characterisation using artificial intelligence (AI). Methods IVOCT pullbacks from 5 international centres were analysed in a corelab, annotating basic plaque components, inflammatory markers and other structures. A deep convolutional network with encoding-decoding architecture and pseudo-3D input was developed ...
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    4. Predictors of Coronary Plaque Erosion in Current and Non-Current Smokers With ST-Segment Elevation Myocardial Infarction ― An Optical Coherence Tomography Study ―

      Predictors of Coronary Plaque Erosion in Current and Non-Current Smokers With ST-Segment Elevation Myocardial Infarction ― An Optical Coherence Tomography Study ―
      Background: Smoking is an important risk factor of plaque erosion. This study aimed to investigate the predictors of plaque erosion in current and non-current smokers presenting with ST-segment elevation myocardial infarction (STEMI). Methods and Results: A total of 1,320 STEMI patients with culprit plaque rupture or plaque erosion detected by pre-intervention optical coherence tomography were divided into a current smoking group (n=715) and non-current smoking group (n=605 ...
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    5. Morphological Characteristics of Eroded Plaques with Noncritical Coronary Stenosis: An Optical Coherence Tomography Study

      Morphological Characteristics of Eroded Plaques with Noncritical Coronary Stenosis: An Optical Coherence Tomography Study
      Aims: Recent studies suggested plaque erosion with noncritical stenosis could be treated distinctly from that with critical stenosis, but their morphological features remained largely unknown. The present study aimed to investigate morphological features of eroded plaques with different lumen stenosis using optical coherence tomography (OCT). Methods: A total of 348 ST-segment elevated myocardial infarction patients with culprit OCT-defined plaque erosion (OCT-erosion) were analyzed. Based on the severity of lumen area ...
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    6. Association between food and nutrients intakes and coronary plaque vulnerability in patients with coronary heart disease: An optical coherence tomography study

      Association between food and nutrients intakes and coronary plaque vulnerability in patients with coronary heart disease: An optical coherence tomography study
      Background and aims: Dietary intakes play important roles in the prevention and treatment of coronary heart disease (CHD). Coronary plaque vulnerability is the key mechanism leading to CHD progression. We aimed to explore the association between dietary intakes and plaque vulnerability via optical coherence tomography (OCT). Methods and results: A total of 314 CHD patients were included in this study. Dietary intake status was assessed by semi-quantitative food frequency questionnaire ...
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    7. Identifying Diabetic Macular Edema and Other Retinal Diseases by Optical Coherence Tomography Image and Multiscale Deep Learning

      Identifying Diabetic Macular Edema and Other Retinal Diseases by Optical Coherence Tomography Image and Multiscale Deep Learning
      ...er Science, Nankai University, Tianjin 300350, People’s Republic of China; 4The Second Affiliated Hospital of Harbin Medical University, Department of Plastic and Cosmetic Surgery, Harbin, Heilongjiang, 150081, People’s ...
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    8. Systemic and local factors associated with reduced thrombolysis in myocardial infarction flow in ST-segment elevation myocardial infarction patients with plaque erosion detected by intravascular optical coherence tomography

      Systemic and local factors associated with reduced thrombolysis in myocardial infarction flow in ST-segment elevation myocardial infarction patients with plaque erosion detected by intravascular optical coherence tomography
      Local factors of plaque rupture (e.g. lipid burden) are related to preprocedural thrombolysis in myocardial infarction (TIMI) flow grade during primary percutaneous coronary intervention (PCI). However, the pathological mechanism differs between plaque erosion and rupture. We aimed to identify the factors associated with reduced TIMI flow in plaque erosion. A total of 329 ST-segment elevation myocardial infarction (STEMI) patients with optical coherence tomography (OCT) identified plaque erosion were divided ...
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    9. Association of ABO blood groups and non-culprit plaque characteristics in acute coronary syndrome: an optical coherence tomography study

      Association of ABO blood groups and non-culprit plaque characteristics in acute coronary syndrome: an optical coherence tomography study
      Background: Cardiovascular disease (CVD) poses a serious threat to human health. Research shows that ABO blood groups, especially non-O blood types, are closely related to the incidence of cardiovascular diseases (CVDs). This study aimed to determine the associations of blood types with non-culprit coronary plaque characteristics using optical coherence tomography (OCT). Methods: A total of 257 acute coronary syndrome (ACS) patients (average age, 59.3910.08 years, 80% male) who ...
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    10. Incidence and Predictors of Neoatherosclerosis in Patients with Early In-Stent Restenosis Determined Using Optical Coherence Tomography

      Incidence and Predictors of Neoatherosclerosis in Patients with Early In-Stent Restenosis Determined Using Optical Coherence Tomography
      Summary In-stent restenosis (ISR) still exists after drug-eluting stent (DES) implantation, even up to one year. The incidence and risk factors for neoatherosclerosis in patients with early ISR have not yet been elucidated. Here, we used optical coherence tomography (OCT) to evaluate the incidence and predictors of neoatherosclerosis in patients with early ISRs. OCT was performed on ISR lesions in 185 patients in order to detect neoatherosclerosis. The median follow-up ...
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    11. Full-Range Line-Field Optical Coherence Tomography for High-Accuracy Measurements of Optical Lens

      Full-Range Line-Field Optical Coherence Tomography for High-Accuracy Measurements of Optical Lens
      A full-range line-field Fourier-domain optical coherence tomography (LF-FDOCT) system with an accuracy at nanoscale was proposed for high-accuracy measurements of optical lens surface profile. The LF surface curve information of optical lens could be obtained in one measurement which does not need point-by-point scanning used in the traditional 1-D FDOCT system. The measurement accuracy of surface profile curve could be improved from micrometer scale to nanoscale by applying spectral center ...
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    12. Unexpected Findings and Tailored Treatments of In-Stent Restenosis: Novel Insights from Optical Coherence Tomography

      Unexpected Findings and Tailored Treatments of In-Stent Restenosis: Novel Insights from Optical Coherence Tomography
      A 68-year-old man was admitted to our hospital with unstable angina. His medical history was remarkable for an acute myocardial infarction one year ago, treated with a zotarolimus-eluting stent (3.530 mm) in the mid right coronary artery. Coronary angiography showed a diffused in-stent restenosis (ISR) with haziness and filling defects (Figure 1A, Video 1). In order to identify the underlying mechanisms of ISR, optical coherence tomography (OCT) was performed ...
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    13. The association between glucose-related variables and plaque morphology in patients with ST-segment elevated myocardial infarction

      The association between glucose-related variables and plaque morphology in patients with ST-segment elevated myocardial infarction
      Plaque rupture (PR) and plaque erosion (PE) are main causes of acute myocardial infarction with different demographic and histology characteristics and need different treatment strategy. PR and PE can be identified with optical coherence tomography (OCT) accurately, but convenient and effective noninvasive markers for them are rarely found. History of diabetes mellitus (DM) was reported to be a potential predictor of PR in ST-segment elevated myocardial infarction (STEMI) patients, but ...
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    14. Optical Coherence Tomography Angiography Evaluation of Ocular Changes in Patients With Carotid Artery Stenosis

      Optical Coherence Tomography Angiography Evaluation of Ocular Changes in Patients With Carotid Artery Stenosis
      A growing body of research indicates that abnormal ocular microvascular features may serve as a novel biomarker reflecting the severity of underlying cardiovascular, neurodegenerative, and microvascular disease. Since blood flow to the retina is predominantly supplied by the internal carotid artery (ICA), we hypothesized that ocular microvasculature and structure changes may reflect the disease status or therapeutic effects in patients with carotid artery stenosis. Optical coherence tomography angiography (OCTA) is ...
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    15. Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography

      Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography
      Plasma ceramides (Cer), a subset of bioactive lipids, have mechanistic links to development of atherosclerosis and are related to major adverse cardiovascular events (MACEs). Previous researches have demonstrated vulnerable plaques contribute to acute cardiovascular events and poor prognosis. This study aimed to explore the associations between Cer and culprit plaque characterizations evaluated by optical coherence tomography (OCT). It was found that plasma Cer are associated with culprit plaque vulnerability evaluated ...
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    16. Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent

      Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent
      This consensus document is the second of two reports summarizing the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) on the clinical use of intracoronary imaging including intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near infrared spectroscopy (NIRS)-IVUS. Beyond guidance of stent selection and optimization of deployment, invasive imaging facilitates angiographic interpretation and may guide treatment in acute coronary syndrome. Intravascular ...
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  2. About Harbin Medical University

    Harbin Medical University

    Harbin Medical University is a public university located in Harbin, Heilongjiang , China . It was established in 1926 as Harbin Medical College. It was renamed to University in 1958.  Harbin, a beautiful city well-known for its ice and snow  and reputed as “Eastern Paris”. HMU has a  scenic view on the campus dotted with ancient-style buildings, with a total  area of 2.36 million square meters.