1. Haoyu Chen

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    1. Mentioned In 24 Articles

    2. Effect Of Optic Disk—Fovea Distance On Measurements Of Individual Macular Intraretinal Layers In Normal Subjects

      Effect Of Optic Disk—Fovea Distance On Measurements Of Individual Macular Intraretinal Layers In Normal Subjects
      Purpose: To investigate the effect of optic diskfovea distance (DFD) on measurements of macular intraretinal layers using spectral domain optical coherence tomography in normal subjects. Methods: One hundred and eighty-two eyes from 182 normal subjects were imaged using spectral domain optical coherence tomography. The average thicknesses of eight macular intraretinal layers were measured using an automatic segmentation algorithm. Partial correlation test and multiple regression analysis were used to determine the ...
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    3. Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects

      Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects
      Purpose To determine the influence of the optic discfovea distance (DFD) on the normative classifications based on thickness measurements of macular inner retinal layers with spectral-domain optical coherence tomography (OCT) in healthy subjects. Methods A total of 182 eyes from 182 healthy subjects were included (mean (SD) spherical equivalent 0.8 (1.9) dioptres). We performed macula and optic disc imaging with the Topcon 3D OCT 2000. The thickness of ...
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    4. Relationship between Optical Intensity on Optical Coherence Tomography and Retinal Ischemia in Branch Retinal Vein Occlusion

      Relationship between Optical Intensity on Optical Coherence Tomography and Retinal Ischemia in Branch Retinal Vein Occlusion
      Branch retinal vein occlusion (BRVO) may be complicated with retinal ischemia in some cases. The purpose of the current study is to investigate the relationship between optical intensity on optical coherence tomography (OCT) and retinal ischemia in BRVO. Twenty-seven eyes diagnosed with BRVO without macular edema were classified into two groups based on the presence or absence of retinal ischemia. The optical intensity of inner retinal layers and photoreceptor inner ...
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    5. Repeatability, interocular correlation and agreement of quantitative swept-source optical coherence tomography angiography macular metrics in healthy subjects

      Repeatability, interocular correlation and agreement of quantitative swept-source optical coherence tomography angiography macular metrics in healthy subjects
      Purpose To investigate the repeatability, interocular correlation and agreement of quantitative swept-source optical coherence tomography angiography (SS-OCTA) metrics in healthy subjects. Methods Thirty-three healthy normal subjects were enrolled. The macula was scanned four times by an SS-OCTA system using the 3mm3mm mode. The superficial capillary map images were analysed using a MATLAB program. A series of parameters were measured: foveal avascular zone (FAZ) area, FAZ perimeter, FAZ circularity, parafoveal vessel ...
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    6. Shared-hole graph search with adaptive constraints for 3D optic nerve head optical coherence tomography image segmentation

      Shared-hole graph search with adaptive constraints for 3D optic nerve head optical coherence tomography image segmentation
      Optic nerve head (ONH) is a crucial region for glaucoma detection and tracking based on spectral domain optical coherence tomography (SD-OCT) images. In this region, the existence of a hole structure makes retinal layer segmentation and analysis very challenging. To improve retinal layer segmentation, we propose a 3D method for ONH centered SD-OCT image segmentation, which is based on a modified graph search algorithm with a shared-hole and locally adaptive ...
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    7. Automated segmentation of choroidal neovascularization in optical coherence tomography images using multi-scale convolutional neural networks with structure prior

      Automated segmentation of choroidal neovascularization in optical coherence tomography images using multi-scale convolutional neural networks with structure prior
      Automated segmentation of choroidal neovascularization (CNV) in optical coherence tomography (OCT) images plays an important role for the treatment of CNV disease. This paper proposes multi-scale convolutional neural networks with structure prior to segment CNV from OCT data. The proposed framework consists of two stages. In the first stage, the structure prior learning method based on sparse representation-based classification and the local potential function is developed to capture the global ...
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    8. Automated framework for intraretinal cystoid macular edema segmentation in three-dimensional optical coherence tomography images with macular hole

      Automated framework for intraretinal cystoid macular edema segmentation in three-dimensional optical coherence tomography images with macular hole
      Cystoid macular edema (CME) and macular hole (MH) are the leading causes for visual loss in retinal diseases. The volume of the CMEs can be an accurate predictor for visual prognosis. This paper presents an automatic method to segment the CMEs from the abnormal retina with coexistence of MH in three-dimensional-optical coherence tomography images. The proposed framework consists of preprocessing and CMEs segmentation. The preprocessing part includes denoising, intraretinal layers ...
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    9. Nonrigid registration of 3D longitudinal optical coherence tomography volumes with choroidal neovascularization

      Nonrigid registration of 3D longitudinal optical coherence tomography volumes with choroidal neovascularization
      In this paper, we propose a 3D registration method for retinal optical coherence tomography (OCT) volumes. The proposed method consists of five main steps: First, a projection image of the 3D OCT scan is created. Second, the vessel enhancement filter is applied on the projection image to detect vessel shadow. Third, landmark points are extracted based on both vessel positions and layer information. Fourth, the coherent point drift method is ...
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    10. Graph search: active appearance model based automated segmentation of retinal layers for optic nerve head centered OCT images

      Graph search: active appearance model based automated segmentation of retinal layers for optic nerve head centered OCT images
      In this paper, a novel approach combining the active appearance model (AAM) and graph search is proposed to segment retinal layers for optic nerve head(ONH) centered optical coherence tomography(OCT) images. The method includes two parts: preprocessing and layer segmentation. During the preprocessing phase, images is first filtered for denoising, then the B-scans are flattened. During layer segmentation, the AAM is first used to obtain the coarse segmentation results ...
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    11. Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography

      Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography
      Early detection of neoplastic changes remains a critical challenge in clinical cancer diagnosis and treatment. Many cancers arise from epithelial layers such as those of the gastrointestinal (GI) tract. Current standard endoscopic technology is difficult to detect the subsurface lesions. In this research, we investigated the feasibility of a novel multi-modal optical imaging approach including high-resolution optical coherence tomography (OCT) and high-sensitivity fluorescence laminar optical tomography (FLOT) for structural and ...
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    12. Change of Optical Intensity during Healing Process of Corneal Wound on Anterior Segment Optical Coherence Tomography

      Change of Optical Intensity during Healing Process of Corneal Wound on Anterior Segment Optical Coherence Tomography
      The purpose of this study is to investigate the process of corneal wound healing after penetrating injury with the change in optical intensity on anterior segment optical coherence tomography (AS-OCT) and to investigate factors associated with severity of corneal scar. Forty-seven eyes from 47 patients with repaired corneal laceration were included. AS-OCT was performed on 1day, 1week, 1, 3 and 6 months after primary repair. Internal aberrations of wound edges ...
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      Mentions: Haoyu Chen
    13. A framework for classification and segmentation of branch retinal artery occlusion in SD-OCT

      A framework for classification and segmentation of branch retinal artery occlusion in SD-OCT
      Branch retinal artery occlusion (BRAO) is an ocular emergency which could lead to blindness. Quantitative analysis of BRAO region in the retina is very needed to assessment of the severity of retinal ischemia. In this paper, a fully automatic framework was proposed to classify and segment BRAO based on 3D spectral-domain optical coherence tomography (SD-OCT) images. To the best of our knowledge, this is the first automatic 3D BRAO segmentation ...
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      Mentions: Haoyu Chen
    14. CORRELATION OF OPTICAL INTENSITY ON OPTICAL COHERENCE TOMOGRAPHY AND VISUAL OUTCOME IN CENTRAL RETINAL ARTERY OCCLUSION

      CORRELATION OF OPTICAL INTENSITY ON OPTICAL COHERENCE TOMOGRAPHY AND VISUAL OUTCOME IN CENTRAL RETINAL ARTERY OCCLUSION
      Purpose: To investigate the relationship between optical coherence tomography (OCT) characteristics at baseline and visual outcome in central retinal artery occlusion (CRAO). Methods: The medical charts and OCT images of patients with central retinal artery occlusion with follow-up for more than 90 days were reviewed. Optical intensities of inner retinal layers, outer nuclear layers, and photoreceptor/retinal pigment epithelium were measured using Image J software. Optical intensity ratio was calculated ...
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      Mentions: Haoyu Chen
    15. Profile and Determinants of Retinal Optical Intensity in Normal Eyes with Spectral Domain Optical ...

      Profile and Determinants of Retinal Optical Intensity in Normal Eyes with Spectral Domain Optical ...
      Purpose To investigate the profile and determinants of retinal optical intensity in normal subjects using 3D spectral domain optical coherence tomography (SD OCT). Methods A total of 231 eyes from 231 healthy subjects ranging in age from 18 to 80 years were included and underwent a 3D OCT scan. Forty-four eyes were randomly chosen to be scanned by two operators for reproducibility analysis. Distribution of optical intensity of each layer ...
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    16. Prediction of spontaneous closure of traumatic macular hole with spectral domain optical coherence tomography

      Prediction of spontaneous closure of traumatic macular hole with spectral domain optical coherence tomography
      It has been known that some traumatic macular holes can close spontaneously. However, knowledge about the types of macular hole that can close spontaneously is limited. In this retrospective study, we investigated patients with traumatic macular hole who were followed-up for at least 6 months without any surgical intervention. Clinical data and spectral domain optical coherence tomography (SD-OCT) images were compared between groups with and without macular hole closure. Overall ...
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    17. 1-15 of 24 1 2 »
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  2. About Haoyu Chen

    Haoyu Chen is at the Joint Shantou International Eye Center of Shantou University in China.