1. Hannover Medical School

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    1. Mentioned In 17 Articles

    2. Intraoperative optical coherence tomography and ab interno trabecular meshwork surgery with the Trabectome

      Intraoperative optical coherence tomography and ab interno trabecular meshwork surgery with the Trabectome
      Importance: This study is the first description of the use of the intraoperative optical coherence tomography (iOCT) for trabecular meshwork surgery with the Trabectome in a regular clinical setting. Background: The aim of this study is to evaluate intraoperatively the immediate success of ab interno trabeculotomy with the Trabectome defined as a removal of the trabecular meshwork. Design: This is a retrospective clinical study performed in the University Eye Hospital ...
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    3. Adaptive optics assisted and optical coherence tomography guided fs-laser system for ophthalmic surgery in the posterior eye

      Adaptive optics assisted and optical coherence tomography guided fs-laser system for ophthalmic surgery in the posterior eye
      While fs-lasers are clinically established for surgery in the anterior eye, their use in the posterior eye is impeded by aberrations and focus position errors. We implemented a laboratory system to investigate whether fs-laser surgery in the posterior eye is made more feasible by aberration correction and tomographic image guidance. Aberration correction is obtained by adaptive optics (AO) and the image guidance is accomplished by optical coherence tomography (OCT). System ...
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    4. Longitudinal time‑domain optic coherence study of retinal nerve fiber layer in IFNβ‑treated and untreated multiple sclerosis patients

      Longitudinal time‑domain optic coherence study of retinal nerve fiber layer in IFNβ‑treated and untreated multiple sclerosis patients
      Quantification of the retinal nerve fiber layer (RNFL) by optical coherence tomography (OCT) has been proposed to provide an indirect measure for retinal axonal loss. The aim of the present study was to determine whether interferon beta (IFN) treatment impedes retinal axonal loss in multiple sclerosis (MS) patients. A total of 48 patients with MS (24 IFN‑1b‑treated and 24 untreated subjects) and 12 healthy controls were enrolled in ...
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    5. The short-term effects of aflibercept on the size of choroidal neovascularization lesion in treatment-resistant neovascular age-related macular degeneration as determined by spectral-domain optical coherence tomography

      The short-term effects of aflibercept on the size of choroidal neovascularization lesion in treatment-resistant neovascular age-related macular degeneration as determined by spectral-domain optical coherence tomography
      Background and Objectives To evaluate the changes in the size of choroidal neovascularization (CNV) lesion using spectral domain-optical coherence tomography (SD-OCT) in patients with treatment-resistant neovascular age-related macular degeneration (AMD) who were switched from ranibizumab to aflibercept. Materials and Methods In this prospective case-series, 33 eyes of 30 patients with treatment-resistant neovascular AMD were included. Treatment-resistant neovascular AMD was defined as choriodal neovascularization secondary to AMD determined by subretinal fluid ...
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    6. Effect of saline inhalation on vocal fold epithelial morphology evaluated by optical coherence tomography

      Effect of saline inhalation on vocal fold epithelial morphology evaluated by optical coherence tomography
      Objectives/Hypothesis Examination of tissue structures by optical coherence tomography (OCT) has been shown to be useful on mucous membranes of the vocal folds, but so far its application to the human larynx has been limited because it is technically cumbersome and usually needs to be performed with sedation. Here a newly developed, noninvasive combined laryngoscopy and OCT procedure is described and its suitability for ambulatory OCT studies evaluated. Because ...
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    7. One step geometrical calibration method for optical coherence tomography

      One step geometrical calibration method for optical coherence tomography
      We present a novel one-step calibration methodology for geometrical distortion correction for optical coherence tomography (OCT). A calibration standard especially designed for OCT is introduced, which consists of an array of inverse pyramidal structures. The use of multiple landmarks situated on four different height levels on the pyramids allow performing a 3D geometrical calibration. The calibration procedure itself is based on a parametric model of the OCT beam propagation. It ...
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    8. Automated working distance adjustment enables optical coherence tomography of the human larynx in awake patients

      Automated working distance adjustment enables optical coherence tomography of the human larynx in awake patients
      Optical coherence tomography (OCT) provides structural information of laryngeal tissue which is comparable to histopathological analysis of biopsies taken under general anesthesia. In awake patients, movements impede clinically useful OCT acquisition. Therefore, an automatic compensation of movements was implemented into a swept source OCT-laryngoscope. Video and OCT beam path were combined in one tube of 10-mm diameter. Segmented OCT images served as distance sensor and a feedback control adjusted the ...
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    9. Assessment of β-zone peripapillary atrophy by optical coherence tomography and scanning laser ophthalmoscopy imaging in glaucoma patients

      Assessment of β-zone peripapillary atrophy by optical coherence tomography and scanning laser ophthalmoscopy imaging in glaucoma patients
      ...pik,2 Michael Ulbig,2 Christoph Hirneiss,2 Aljoscha S Neubauer,2 Marcus Kernt2 1Department of Ophthalmology, Hannover Medical School, Hannover, Germany; 2Department of Ophthalmology, Ludwig-Maximilians-University, Munic...
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    10. A one step vs. a multi step geometric calibration of an optical coherence tomography

      A one step vs. a multi step geometric calibration of an optical coherence tomography
      This contribution compares two approaches for the geometric calibration of an optical coherence tomography (OCT) which forms part of a medical navigation system. For this purpose, a one step and a multi step calibration is performed with a self-produced 3D reference structure and a high-accurate 6 degrees of freedom (DoF) parallel robot, respectively. These 3D landmark-based geometric calibrations are based on the identification of a parameterized grey-box OCT model. We ...
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    11. Compensating Motion Artifacts of 3D in vivo SD-OCT Scans

      Compensating Motion Artifacts of 3D in vivo SD-OCT Scans
      We propose a probabilistic approach for compensating motion artifacts in 3D in vivo SD-OCT (spectral-domain optical coherence tomography) tomographs. Subject movement causing axial image shifting is a major problem for in vivo imaging. Our technique is applied to analyze the tissue at percutaneous implants recorded with SD-OCT in 3D. The key challenge is to distinguish between motion and the natural 3D spatial structure of the scanned subject. To achieve this ...
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    12. Feature Of The Week 12/4/11: Researchers in Hannover Germany Utilize OCT to Measure Skin Swelling Along Percutaneous Implants

      Feature Of The Week 12/4/11: Researchers in Hannover Germany Utilize OCT to Measure Skin Swelling Along Percutaneous Implants
      ...5540S (2010) Researchers from the Leibniz University of Hannover (LUH), Laser Zentrum Hannover (LZH), and the Hannover Medical School (MHH) used OCT to measure skin swelling along percutaneous implants. An undistortion t...
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    13. Integration of an Optical Coherence Tomography (OCT) System into an Examination Incubator to facilitate in vivo Imaging of Cardiovascular Development in higher vertebrate Embryos under stable physiological Conditions

      Integration of an Optical Coherence Tomography (OCT) System into an Examination Incubator to facilitate in vivo Imaging of Cardiovascular Development in higher vertebrate Embryos under stable physiological Conditions
      ...ion ^, ^E-mail The Corresponding Author ^a Department of Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany ^b DTU Fotonik, Department of Photonic...
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    14. Field programmable gate-array-based real-time optical Doppler tomography system for in vivo imaging of cardiac dynamics in the chick embryo

      ... Lund Institute of Technology, Department of Physics, P.O. Box 118, SE-221 00 Lund, Sweden Talât Mesud Yelbuz Hannover Medical School, Department of Pediatric Cardiology and Intensive Care Medicine, Carl Neuberg Strasse ...
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  2. About Hannover Medical School

    Hannover Medical School

    Hannover Medical School, founded in 1965, is one of the world's leading university medical centres. Our research and patient care set national and international standards. We are also part of an excellent regional medical network.  Our outstanding success in interdisciplinary collaboration both within the MHH and with extramural scientific institutions is reflected in the fact that the MHH is the German medical university with the greatest volume of grant funding.