1. Habib Samady

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    1. Mentioned In 14 Articles

    2. Establishment of an Automated Algorithm Utilizing Optical Coherence Tomography and Micro-Computed Tomography Imaging to Reconstruct the 3-D Deformed Stent Geometry

      Establishment of an Automated Algorithm Utilizing Optical Coherence Tomography and Micro-Computed Tomography Imaging to Reconstruct the 3-D Deformed Stent Geometry
      Percutaneous coronary intervention (PCI) is the prevalent treatment for coronary artery disease, with hundreds of thousands of stents implanted annually. Computational studies have demonstrated the role of biomechanics in the failure of vascular stents, but clinical studies is this area are limited by a lack of understanding of the deployed stent geometry, which is required to accurately model and predict the stent-induced in vivo biomechanical environment. Herein, we present an ...
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    3. Automatic Segmentation Methods Based on Machine Learning for Intracoronary Optical Coherence Tomography Image

      Automatic Segmentation Methods Based on Machine Learning for Intracoronary Optical Coherence Tomography Image
      Cardiovascular diseases are closely associated with sudden rupture of atherosclerotic plaques. Previous image modalities such as magnetic resonance imaging (MRI) and intravascular ultrasound (IVUS) were unable to identify vulnerable plaques due to their limited resolution. Optical coherence tomography (OCT) is an advanced intravascular imaging technique developed in recent years which has high resolution approximately 10 microns and could provide more accurate morphology of coronary plaque. In particular, it is now ...
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    4. Establishment of an Automated Algorithm Utilizing Optical Coherence Tomography and Micro-Computed Tomography Imaging to Reconstruct the 3D Deformed Stent Geometry

      Establishment of an Automated Algorithm Utilizing Optical Coherence Tomography and Micro-Computed Tomography Imaging to Reconstruct the 3D Deformed Stent Geometry
      Percutaneous coronary intervention (PCI) is the prevalent treatment for coronary artery disease, with hundreds of thousands of stents implanted annually. Computational studies have demonstrated the role of biomechanics in the failure of vascular stents, but clinical studies is this area are limited by a lack of understanding of the deployed stent geometry, which is required to accurately model and predict the stent induced in vivo biomechanical environment. Herein, we present ...
      Read Full Article
    5. Establishment of an Automated Algorithm Utilizing Optical Coherence Tomography and Micro-Computed Tomography Imaging to Reconstruct the 3D Deformed Stent Geometry

      Establishment of an Automated Algorithm Utilizing Optical Coherence Tomography and Micro-Computed Tomography Imaging to Reconstruct the 3D Deformed Stent Geometry
      Percutaneous coronary intervention (PCI) is the prevalent treatment for coronary artery disease, with hundreds of thousands of stents implanted annually. Computational studies have demonstrated the role of biomechanics in the failure of vascular stents, but clinical studies is this area are limited by a lack of understanding of the deployed stent geometry, which is required to accurately model and predict the stent induced in vivo biomechanical environment. Herein, we present ...
      Read Full Article
    6. Combining IVUS and Optical Coherence Tomography for More Accurate Coronary Cap Thickness Quantification and Stress/Strain Calculations: A Patient-Specific Three-Dimensional Fluid-Structure Interaction Modeling Approach

      Combining IVUS and Optical Coherence Tomography for More Accurate Coronary Cap Thickness Quantification and Stress/Strain Calculations: A Patient-Specific Three-Dimensional Fluid-Structure Interaction Modeling Approach
      Accurate cap thickness and stress/strain quantifications are of fundamental importance for vulnerable plaque research. Virtual histology intravascular ultrasound (VH-IVUS) sets cap thickness to zero when cap is under resolution limit and IVUS does not see it. An innovative modeling approach combining IVUS and optical coherence tomography (OCT) is introduced for cap thickness quantification and more accurate cap stress/strain calculations. In vivo IVUS and OCT coronary plaque data were ...
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    7. Temporal Trends in Strut-Level Optical Coherence Tomography Evaluation of Coronary Stent Coverage

      Temporal Trends in Strut-Level Optical Coherence Tomography Evaluation of Coronary Stent Coverage
      Objectives We sought to pool data from all studies with reported strut-level data in human subjects evaluated by optical coherence tomography (OCT) surveillance and to compare the aggregate data of stent strut coverage on a longitudinal temporal timeline from initial implantation for different coronary stent subtypes. Background Delayed strut coverage following drug-eluting stent (DES) implantation is an important contributor to late stent thrombosis (LST). OCT can detect stent strut coverage ...
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    8. Intravascular ultrasound and optical coherence tomography imaging of coronary atherosclerosis

      Intravascular ultrasound and optical coherence tomography imaging of coronary atherosclerosis
      Invasive imaging modalities, in particular intravascular ultrasound (IVUS) and optical coherence tomography (OCT), have become established tools for the in vivo study of coronary atherosclerosis. Their use in clinical studies has confirmed histopathological observations that certain important plaque features, such as thin fibrous caps and large lipid cores, are associated with plaque rupture, the precipitating event for the majority of myocardial infarctions. Serial imaging studies have also successfully been used ...
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    9. Prevalence and Characteristics of TCFA and Degree of Coronary Artery Stenosis An OCT, IVUS, and Angiographic Study

      Prevalence and Characteristics of TCFA and Degree of Coronary Artery Stenosis An OCT, IVUS, and Angiographic Study
      Background The relationship between features of vulnerable plaque and angiographic coronary stenosis is unknown. Objectives The purpose of this study was to systematically investigate the absolute number, relative prevalence, and characteristics of thin-cap fibroatheroma (TCFA) at different degrees of stenosis using optical coherence tomography (OCT), intravascular ultrasound, and coronary angiography. Methods We identified 643 plaques from 255 subjects who underwent OCT imaging in all 3 coronary arteries. They were divided ...
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    10. Computational Fluid Dynamics Simulations of Hemodynamics in Plaque Erosion

      Computational Fluid Dynamics Simulations of Hemodynamics in Plaque Erosion
      We investigated whether local hemodynamics were associated with sites of plaque erosion and hypothesized that patients with plaque erosion have locally elevated WSS magnitude in regions where erosion has occurred. We generated 3D, patient-specific models of coronary arteries from biplane angiographic images in 3 human patients with plaque erosion diagnosed by optical coherence tomography. Using computational fluid dynamics, we simulated pulsatile blood flow and calculated both wall shear stress (WSS ...
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    11. 3D Optical Coherence Tomography (OCT)–An Investigation of Intimal-Medial Thickness (IMT) and Wall Shear Stress (WSS) in a Patient's Coronary Artery

      3D Optical Coherence Tomography (OCT)–An Investigation of Intimal-Medial Thickness (IMT) and Wall Shear Stress (WSS) in a Patient's Coronary Artery
      ... for Assessment of Coronary Arteries and Atherosclerosis. European Heart Journal, 2010 Feb 31(4): 401-415 [3] Habib Samady, Parham Eshtehardi, Michael C McDaniel, Jin Suo, Saurabh S Dhawan, Charles Maynard, Lucas H Timmi...
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    12. Feature Of The Week 7/10/11: Intravascular Imaging Tools in the Cardiac Catheterization Laboratory: Comprehensive Assessment of Anatomy and Physiology

      Feature Of The Week 7/10/11: Intravascular Imaging Tools in the Cardiac Catheterization Laboratory: Comprehensive Assessment of Anatomy and Physiology
      Researchers from Emory University School of Medicine recently published a review article on Intravascular Imaging Tools in the Cardiac Catheterization Laboratory including Coronary Flow Reserve, Fractional Flow Reserve, Intravascular Ultrasound, Angioscopy, Wall Shear Stress Profiling, and Optical Coherence Tomography. Below is a summary of that article.Intravascular imaging modalities have an imperative role in contemporary cardiovascular research. Currently, there are several invasive imaging modalities available in the cardiac catheterization laboratory ...
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  2. About Habib Samady

    Habib Samady

    Habib Samady, MD, FACC, FSCAI is a Professor of Medicine and Director of Interventional Cardiology at the Andreas Gruentzig Cardiovascular Center and Emory Clinical Cardiovascular Research Institute of the Emory University School of Medicine.