1. Guy Lamouche

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    1. Mentioned In 41 Articles

    2. External amplification of OCT swept-sources for challenging applications: from 10 mW to more than 120 mW

      External amplification of OCT swept-sources for challenging applications: from 10 mW to more than 120 mW
      For bioimaging applications, commercial swept-sources currently provide enough power (tens of milliwatts) insuring good imaging condition without damaging the tissues. For industrial applications, more power is needed since the amount of light collected can be very low due to challenging measurement conditions or due to poor sample reflectivity. To address this challenge, we explore three different setups to externally amplify the output of a commercial swept-source: a booster semiconductor optical ...
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    3. Processing to determine optical parameters of atherosclerotic disease from phantom and clinical intravascular optical coherence tomography three-dimensional pullbacks

      Processing to determine optical parameters of atherosclerotic disease from phantom and clinical intravascular optical coherence tomography three-dimensional pullbacks
      Analysis of intravascular optical coherence tomography (IVOCT) data has potential for real-time in vivo plaque classification. We developed a processing pipeline on a three-dimensional local region of support for estimation of optical properties of atherosclerotic plaques from coronary artery, IVOCT pullbacks. Using realistic coronary artery disease phantoms, we determined insignificant differences in mean and standard deviation estimates between our pullback analyses and more conventional processing of stationary acquisitions with frame ...
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    4. Multilayered tissue phantoms, fabrication methods, and use

      Multilayered tissue phantoms, fabrication methods, and use
      A method for producing a multilayer tissue phantom involves successively forming at least two layers, each layer formed by depositing a viscous flowable material over a supporting element or over a previously formed layer of the phantom supported by the supporting element, selectively redistributing the material while material is solidifying to control a thickness distribution of the layer, and allowing the material to solidify sufficiently to apply a next layer ...
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    5. Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms

      Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms
      We explored the potential of intravascular optical coherence tomography (IVOCT) to assess deformation during angioplasty balloon inflation. Using a semi-compliant balloon and artery phantoms, we considered two experimental scenarios. The goal for the first scenario was to investigate if variation in the elasticity of the structure surrounding the balloon could be sensed by IVOCT monitoring. In this scenario, we used three single-layer phantoms with various mechanical properties. Image analysis was ...
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    6. Review of tissue simulating phantoms with controllable optical, mechanical and structural properties for use in optical coherence tomography

      Review of tissue simulating phantoms with controllable optical, mechanical and structural properties for use in optical coherence tomography
      We review the development of phantoms for optical coherence tomography (OCT) designed to replicate the optical, mechanical and structural properties of a range of tissues. Such phantoms are a key requirement for the continued development of OCT techniques and applications. We focus on phantoms based on silicone, fibrin and poly(vinyl alcohol) cryogels (PVA-C), as we believe these materials hold the most promise for durable and accurate replication of tissue ...
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    7. Real-time Control of Angioplasty Balloon Inflation Based on Feedback from Intravascular Optical Coherence Tomography: Experimental Validation on an Excised Heart and a Beating Heart Model

      Real-time Control of Angioplasty Balloon Inflation Based on Feedback from Intravascular Optical Coherence Tomography: Experimental Validation on an Excised Heart and a Beating Heart Model
      We report on real-time control of balloon inflation inside porcine arteries. In a first step, experiments were done in a coronary artery of an excised heart. In a second step, experiments were done in a beating heart setup providing conditions very close to in vivo conditions without the complications. A programmable syringe pump was used to inflate a compliant balloon in arteries, while intravascular optical coherence tomography (IVOCT) monitoring was ...
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    8. Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation
      ...ukasz Koltowski, MD, Takashi Kubo, MD, PhD, Teruyoshi Kume, MD, Hiroyuki Kyono, MD, Cheung Chi Simon Lam, MD, Guy Lamouche, PhD, David P. Lee, MD, Martin B. Leon, MD, Akiko Maehara, MD, Olivia Manfrini, MD, Gary S. Mintz...
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    9. OCT Phantoms Initiative: A new effort to bring standardized tools for OCT system characterization and validation to the community

      OCT Phantoms Initiative: A new effort to bring standardized tools for OCT system characterization and validation to the community
      ....gc.ca.   Anant Agrawal, US Food and Drug Administration Brendan Kennedy, University of Western Australia Guy Lamouche, National Research Council Canada Pete Tomlins, Queen Mary, University of London   If you are ...
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    10. Real-time Control of Angioplasty Balloon Inflation Based on Feedback from Intravascular Optical Coherence Tomography: Preliminary Study on an Artery Phantom

      Real-time Control of Angioplasty Balloon Inflation Based on Feedback from Intravascular Optical Coherence Tomography: Preliminary Study on an Artery Phantom
      A method is proposed to achieve computerized control of angioplasty balloon inflation, based on feedback from intravascular optical coherence tomography (IVOCT). Controlled balloon inflation could benefit clinical applications, cardiovascular research, and medical device industry. The proposed method was experimentally tested for balloon inflation within an artery phantom. During balloon inflation, luminal contour of the phantom was extracted from IVOCT images in real-time. Luminal diameter was estimated from the obtained contour ...
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    11. 1-15 of 41 1 2 3 »
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  2. About Guy Lamouche

    Guy Lamouche

    Guy Lamouche is the team leader of OCT activities at the Industrial Materials Institute (IMI), an institute of the National Research Council Canada. The team has been active in OCT since the late nineties and is working on both biomedical and industrial applications.

     

    Dr. Lamouche completed an Engineering Physics degree in 1986 and a Master of Applied Science degree on guided-wave optics in 1989,  both at Ecole Polytechnique of Montreal. Afterwards, he undertook doctoral studies at University of Toronto on photonic band structure calculation  to finally complete a Ph.D. in Physics at University of Montreal in 1996 on the theoretical study of semiconductor impurity photoionization and of optical properties of quantum structures. As an NSERC postdoctoral fellow (1996-1998), he worked at Université Paris VII, Université Joseph Fourier (Grenoble), and Ecole Polytechnique of Montreal on optical properties of molecules and on quantum structures.

     

    He joined IMI late 1998 initially working on laser-ultrasonic characterization of the microstructure of materials, being group leader of the activities in 2002. He successfully managed a large industrial project to measure the austenitic grain size in steel tubes on the production line using laser ultrasonics. He joined the OCT team in 2003. He has contributed since then to many aspects of the technology for both industrial and biomedical applications.

  3. Quotes

    1. Combining OCT with a balloon deployment system provides an improved platform for angioplasty balloon development and can also be used in the development of next-generation minimally invasive devices for percutaneous -- through the skin -- coronary interventions...It's now possible to monitor balloon inflation within an artery phantom (model) or an excised artery to assess the efficiency of innovative balloon angioplasty or stent deployment procedures.
      In Optical Imaging Technique for Angioplasty