1. Giulio Guagliumi

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    1. Mentioned In 64 Articles

    2. Impact of different stent alloys on human vascular response to everolimus-eluting stent. An optical coherence tomography study. The OCTEVEREST

      Impact of different stent alloys on human vascular response to everolimus-eluting stent. An optical coherence tomography study. The OCTEVEREST
      Background: New generation drug-eluting stents (DES) incorporate thinner struts and novel alloys to improve clinical performance. Nevertheless, the impact of novel stent materials and designs on human vascular response to DES remains elusive. We sought to evaluate the in-vivo coronary artery response to platinum-chromium (PtCr) versus cobalt-chromium (CoCr) stents featuring the same durable polymer and antiproliferative drug by optical coherence tomography (OCT). Methods and Results: A total of 42 patients ...
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    3. Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation
      ..., PhD, Marc D. Feldman, MD, Peter Fitzgerald, MD, Hector Garcia, MD, Nieves Gonzalo, MD, Juan F. Granada, MD, Giulio Guagliumi, MD, Niels R. Holm, MD, Yasuhiro Honda, MD, Fumiaki Ikeno, MD, Masanori Kawasaki, MD, Janusz ...
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    4. Serial Assessment of Coronary Artery Response to Paclitaxel-Eluting Stents Using Optical Coherence Tomography

      Serial Assessment of Coronary Artery Response to Paclitaxel-Eluting Stents Using Optical Coherence Tomography
      Background—The paucity of longitudinal, serial high-resolution imaging studies has limited our understanding of in vivo arterial response to drug-eluting stents. We sought to investigate the human coronary response to paclitaxel-eluting stent implantation, using serial optical coherence tomography assessments. Methods and Results—Thirty patients with at least 2 significant coronary lesions in different vessels were treated with a paclitaxel-eluting stent. The most severe stenosis (lesion A) was treated at the ...
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    5. Examination of the In Vivo Mechanisms of Late Drug-Eluting Stent Thrombosis: Findings From Optical Coherence Tomography and Intravascular Ultrasound Imaging

      Examination of the In Vivo Mechanisms of Late Drug-Eluting Stent Thrombosis: Findings From Optical Coherence Tomography and Intravascular Ultrasound Imaging
      ...ter and the Cardiovascular Research Foundation, New York, New York * Reprint requests and correspondence: Dr. Giulio Guagliumi, Cardiovascular Department, Ospedali Riuniti di Bergamo, Largo Barozzi 1, Ingresso 14, 24121 ...
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    6. Impact of Drug Release Kinetics on Vascular Response to Different Zotarolimus-Eluting Stents Implanted in Patients With Long Coronary Stenoses: The LongOCT Study (Optical Coherence Tomography in Long Lesions)

      Impact of Drug Release Kinetics on Vascular Response to Different Zotarolimus-Eluting Stents Implanted in Patients With Long Coronary Stenoses: The LongOCT Study (Optical Coherence Tomography in Long Lesions)
      ...e Medical Center, Case Western Reserve University, Cleveland, Ohio * Reprint requests and correspondence: Dr. Giulio Guagliumi, Cardiovascular Department, Ospedali Riuniti di Bergamo, Largo Barozzi 1, 24128 Bergamo, Ital...
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    7. The impact of an eccentric intravascular ImageWire during coronary optical coherence tomography imaging

      The impact of an eccentric intravascular ImageWire during coronary optical coherence tomography imaging
      Optical Coherence Tomography (OCT) provides high-resolution imaging which enables characterisation of atherosclerosis and vascular response to injury, but to ensure optimal analysis, one must realise potential sources of image distortion. We designed a series of analysesl, using coronary stents as a model, to investigate the influence of wire position on OCT-derived vascular images.
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    8. Strut Coverage and Late Malapposition With Paclitaxel-Eluting Stents Compared With Bare Metal Stents in Acute Myocardial Infarction: OCT Substudy of the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI)

      Strut Coverage and Late Malapposition With Paclitaxel-Eluting Stents Compared With Bare Metal Stents in Acute Myocardial Infarction: OCT Substudy of the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI)
      ...r Research Foundation, New York, NY (G.S.M., O.D., H.P., A.M., E.C., A.J.L., R.M., G.W.S.). Correspondence to Giulio Guagliumi, MD, FESC, Division of Cardiology, Cardiovascular Department, Ospedali Riuniti di Bergamo, La...
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    9. Optical coherence tomography in ST-elevation myocardial infarction treated with novel drug-eluting stent: preprocedural, post implant and 2-month follow-up findings

      Optical coherence tomography in ST-elevation myocardial infarction treated with novel drug-eluting stent: preprocedural, post implant and 2-month follow-up findings
      The use of drug-eluting stents (DES) allowed the reduction in the need for repeat revascularization. At the culprit site in acute myocardial infarction patients treated with first-generation DES, the interaction between the eluted drug and the underlying necrotic core may generate different patterns of pathologic vessel response and delayed healing. A new generation DES intrepide elutes trapidil. Its modes of action are neither cytotoxic nor cytostatic, and may promote normal ...
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    10. Angiographic, IVUS and OCT evaluation of the long-term impact of coronary disease severity at the site of overlapping drug-eluting and bare metal stents: a substudy of the ODESSA trial

      Angiographic, IVUS and OCT evaluation of the long-term impact of coronary disease severity at the site of overlapping drug-eluting and bare metal stents: a substudy of the ODESSA trial
      Background A potentially adverse vascular response to overlapping drug eluting stents (DES) has been suggested in current research. Objective To evaluate the impact of baseline disease severity at the site of stent overlap. Methods and results This is a substudy of ODESSA, a prospective, randomised controlled trial designed to evaluate healing of overlapping stents. 71/77 patients with a total of 86 overlapping stents were studied: 25 sirolimus, 24 paclitaxel ...
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    11. Strut Coverage and Vessel Wall Response to a New-Generation Paclitaxel-Eluting Stent With an Ultrathin Biodegradable Abluminal Polymer: Optical Coherence Tomography Drug-Eluting Stent Investigation (OCTDESI)

      Strut Coverage and Vessel Wall Response to a New-Generation Paclitaxel-Eluting Stent With an Ultrathin Biodegradable Abluminal Polymer: Optical Coherence Tomography Drug-Eluting Stent Investigation (OCTDESI)
      ...r (J.J.P.), Boston, Mass; and Boston Scientific Corporation (D.J.A., K.D.D.), Natick, Mass. Correspondence to Giulio Guagliumi, MD, Interventional Cardiology, Ospedali Riuniti di Bergamo, Largo Barozzi n. 1 - Ingresso 14...
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    12. Strut Coverage and Vessel Wall Response to Zotarolimus-Eluting and Bare-Metal Stents Implanted in Patients With ST-Segment Elevation Myocardial Infarction: The Octami (Optical Coherence Tomography in Acute Myocardial Infarction) Study

      Strut Coverage and Vessel Wall Response to Zotarolimus-Eluting and Bare-Metal Stents Implanted in Patients With ST-Segment Elevation Myocardial Infarction: The Octami (Optical Coherence Tomography in Acute Myocardial Infarction) Study
      ...e Medical Center, Case Western Reserve University, Cleveland, Ohio * Reprint requests and correspondence: Dr. Giulio Guagliumi, Cardiovascular Department, Ospedali Riuniti di Bergamo, Largo Barozzi 1, 24128 Bergamo, Ital...
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    13. Optical Coherence Tomography for EVERolimus Eluting STent

      Optical Coherence Tomography for EVERolimus Eluting STent
      Compared with bare metal stents (BMS), both paclitaxel-eluting stents (PES) and sirolimus-eluting stents (SES) significantly reduce angiographic restenosis and the need for repeat revascularization in coronary arteries across a broad range of patient and lesion types. However the increased risk of very late stent thrombosis represents a major concern for patients treated with both PES and SES. Optical coherence tomography (OCT), a new imaging technique based on the back reflection ...
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    14. 31-45 of 64 « 1 2 3 4 5 »
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  2. About Giulio Guagliumi

    Giulio Guagliumi

    Giulio Guagliumi, MD, is with the Cardiovascular Department, Division of Cardiology, Ospedali Riuniti di Bergamo, Italy.

  3. Quotes

    1. Imaging is more accurate, helps guide decisions and facilitates tailored therapy, especially in younger heart attack patients who more frequently have plaque erosion or non-atherosclerotic coronary artery disease.
      In Expert consensus published on use of imaging to guide heart attack treatment
    2. OCT technology has become increasingly important to help diagnose and treat patients with coronary artery disease. The ILUMIEN OPTIS system is a significant advancement in intravascular imaging technology allowing physicians to comprehensively assess more vessel in less time and more easily plan their PCI procedure. The three-dimensional format of the ILUMIEN OPTIS system provides a more true-to-life perspective of the arteries, which allows for individual decision making and precise guidance of stent placement to optimize coronary interventions.
      In St. Jude Medical Announces European Approval of 3-D Vessel Reconstruction Technology to Aid Physicians in Stent Placement
    3. We are doing a high number of off-label-indication cases, patients and lesions are becoming more and more complex, with more calcification and much less guarantee that in 20 seconds with one balloon, you can have good apposition of the stent and a good job done. And in this case, we need to increase the level of accuracy at the time of implanting and at follow-up: OCT is a new possibility to obtain the best placement. This could be very important in the future.
      In OCT imaging suggests low rates of uncovered/malapposed struts following DES for AMI