1. Giovanni J. Ughi

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    1. Mentioned In 44 Articles

    3. MICRO-IMAGING CATHETERS FOR HIGH-RESOLUTION, IMAGE-GUIDED, ENDOVASCULAR REPAIR OF BRAIN ANEURYSMS

      Explore Query Form Cardiology , Neurology , Funding
      MICRO-IMAGING CATHETERS FOR HIGH-RESOLUTION, IMAGE-GUIDED, ENDOVASCULAR REPAIR OF BRAIN ANEURYSMS
      This program will commercialize a high-speed, high-resolution, neuroendovascular imaging platform that allows neurointerventionalists to directly visualize intravascular devices and their interaction with vessels during treatment of brain aneurysms. The miniaturization of the design features of neurovascular stents and flow-diverters has enabled an explosion of technologies available for endovascular treatment of stroke. However, imaging technology has not kept pace with device technology to enable endovascular surgeons sufficient resolution to adequately visualize ...
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      Mentions: FDA Giovanni J. Ughi Gentuity

    4. In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study

      Explore Home - Springer Cardiology
      In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study
      We sought to assess in-stent variations in fractional flow reserve (FFR) in patients with previous percutaneous coronary intervention (PCI) and to associate any drop in FFR with findings by optical coherence tomography (OCT) imaging. Suboptimal post-PCI FFR values were previously associated with poor outcomes. It is not known to which extent in-stent pressure loss contributes to reduced FFR. In this single-arm observational study, 26 patients who previously underwent PCI with ...
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      Mentions: Leiden University K. U. Leuven Shanghai Jiao Tong University

    5. EuOptical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chro

      Explore eurointervention.org Cardiology
      EuOptical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chro
      Aims: The PRISON IV trial investigated the next-generation sirolimus-eluting stent (SES) with ultra-thin struts and biodegradable polymer against the second-generation everolimus-eluting stent (EES) with thin struts and durable polymer in patients with successfully recanalised chronic total occlusions (CTO). In this study, we examined the secondary optical coherence tomography endpoints. Methods and results: The main PRISON IV trial randomised 330 patients to either SES or EES. At nine months, 281 (85 ...
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      Mentions: Academic Medical Center at the University of Amsterdam Walter Desmet K. U. Leuven

    6. Recent Advances in the Field of Optical Coherence Tomography

      Explore Home - Springer Cardiology
      Recent Advances in the Field of Optical Coherence Tomography
      Purpose of Review The scope of this text is to critically review the most important recent advances in the field of optical coherence tomography, both from a clinical, scientific, and technical point of view. Recent Findings In recent years, important steps forward have been put in the field of optimization of PCI (with a focus on optimal sizing of stents and optimization of stent expansion after implantation) and the differentiation ...
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      Mentions: Giovanni J. Ughi Tom Adriaenssens

    7. Optical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chroni

      Explore eurointervention.org Cardiology
      Optical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chroni
      Aims: The PRISON IV trial investigated the next-generation sirolimus-eluting stent (SES) with ultra-thin struts and biodegradable polymer against the second-generation everolimus-eluting stent (EES) with thin struts and durable polymer in patients with successfully recanalised chronic total occlusions (CTO). In this study, we examined the secondary optical coherence tomography endpoints. Methods and results: The main PRISON IV trial randomised 330 patients to either SES or EES. At nine months, 281 (85 ...
      Read Full Article
      Mentions: Arnaud Dubois Academic Medical Center at the University of Amsterdam Walter Desmet

    8. Optical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chroni

      Explore eurointervention.org Cardiology
      Optical coherence tomography findings: insights from the “randomised multicentre trial investigating angiographic outcomes of hybrid sirolimus-eluting stents with biodegradable polymer compared with everolimus-eluting stents with durable polymer in chroni
      Aims: The PRISON IV trial investigated the next-generation sirolimus-eluting stent (SES) with ultra-thin struts and biodegradable polymer against the second-generation everolimus-eluting stent (EES) with thin struts and durable polymer in patients with successfully recanalised chronic total occlusions (CTO). In this study, we examined the secondary optical coherence tomography endpoints. Methods and results: The main PRISON IV trial randomised 330 patients to either SES or EES. At nine months, 281 (85 ...
      Read Full Article
      Mentions: Academic Medical Center at the University of Amsterdam Walter Desmet K. U. Leuven

    9. IMAGE-GUIDED ENDOVASCULAR NEUROSURGERY: HIGH-RESOLUTION CEREBROVASCULAR IMAGING

      Explore Query Form Cardiology , Neurology , Funding
      IMAGE-GUIDED ENDOVASCULAR NEUROSURGERY: HIGH-RESOLUTION CEREBROVASCULAR IMAGING
      The goal of this program is the development of a high-resolution, neuroendovascular imaging platform that provides detailed information on intravascular devices used to treat brain aneurysms. Miniaturization of the design features of neurovascular stents and flow-diverters (FD) with braided wires of 20 m and laser cut features of 10 m, has enabled an explosion of technology available for endovascular treatment of stroke. Despite these advances, however, several questions remain unanswered ...
      Read Full Article
      Mentions: FDA Giovanni J. Ughi Gentuity

    10. EuroIntervention Automated characterisation of lipid core plaques in vivo by quantitative optical coherence tomography tissue type imaging

      Explore eurointervention.org Cardiology
      EuroIntervention Automated characterisation of lipid core plaques in vivo by quantitative optical coherence tomography tissue type imaging
      Aims: Qualitative criteria for plaque tissue characterisation by OCT are well established, but quantitative methods lack systematic validation in vivo . High optical attenuation coefficient t has been associated with unstable plaque features, such as lipid core. The purpose of this study was to validate optical coherence tomography (OCT) attenuation imaging for tissue characterisation in vivo , specifically to detect lipid core in coronary atherosclerotic plaques, and to evaluate quantitatively the ability ...
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      Mentions: Massachusetts General Hospital Harvard University Evelyn Regar

    11. Targeted Near-Infrared Fluorescence Imaging of Atherosclerosis

      Explore ScienceDirect Cardiology
      Targeted Near-Infrared Fluorescence Imaging of Atherosclerosis
      Objectives This study sought to determine whether indocyanine green (ICG)enhanced near-infrared fluorescence (NIRF) imaging can illuminate high-risk histologic plaque features of human carotid atherosclerosis, and in coronary atheroma of living swine, using intravascular NIRF-optical coherence tomography (OCT) imaging. Background New translatable imaging approaches are needed to identify high-risk biological signatures of atheroma. ICG is a U.S. Food and Drug Administrationapproved NIRF imaging agent that experimentally targets plaque macrophages ...
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      Mentions: Guillermo J. Tearney Beth Israel Deaconess Medical Center Brigham and Women’s Hospital

    12. Anatomical and functional assessment of Tryton bifurcation stent before and after final kissing balloon dilatation: Evaluations by three-dimensional coronary angiography, optical coherence tomography imaging and fractional flow reserve

      Explore Wiley Online Library Cardiology
      Anatomical and functional assessment of Tryton bifurcation stent before and after final kissing balloon dilatation: Evaluations by three-dimensional coronary angiography, optical coherence tomography imaging and fractional flow reserve
      Objectives To assess the anatomical and functional impact of final kissing balloon inflation (FKBI) after implantation of a dedicated bifurcation stent system. Background Current evidence suggests clinical benefit of FKBI in patients undergoing bifurcation dilatation using the Tryton side branch stent (Tryton-SBS). We hypothesized that FKBI improves anatomical reconstruction and functional results of bifurcation treated by Tryton-SBS. Methods An unselected group of patients with complex bifurcation coronary lesions undergoing percutaneous ...
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      Mentions: Martin B. Leon K. U. Leuven Giovanni J. Ughi

    13. Clinical Characterization of Coronary Atherosclerosis With Dual-Modality OCT and Near-Infrared Autofluorescence Imaging

      Explore ScienceDirect Cardiology
      Clinical Characterization of Coronary Atherosclerosis With Dual-Modality OCT and Near-Infrared Autofluorescence Imaging
      ...o that obtained by structural imaging alone. JACC: Cardiovascular Imaging, Volume null, Issue null, Page null Giovanni J. Ughi, Hao Wang, Edouard Gerbaud, Joseph A. Gardecki, Ali M. Fard, Ehsan Hamidi, Paulino Vacas-Jacq...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    14. Optical coherence tomography-based assessment of bifurcation stenting using the Axxess™ Biolimus A9™-eluting stent system

      Explore eurointervention.org Cardiology
      Optical coherence tomography-based assessment of bifurcation stenting using the Axxess™ Biolimus A9™-eluting stent system
      Bifurcation lesions are associated with increased procedural complications and worse long-term outcome. Multiple techniques are available, including the dedicated drug-eluting Axxess stent system (Biosensors International Ltd., Singapore, Singapore), providing complete bifurcation support without covering the carina. Low rates of restenosis in both main vessel (MV) and side branch (SB) have been demonstrated. High-resolution imaging techniques such as intravascular optical coherence tomography (IV-OCT) may help the positioning and implantation of the ...
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      Mentions: Biosensors International K. U. Leuven Giovanni J. Ughi

    15. Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy
      Optical coherence tomography (OCT) is an optical diagnostic modality that can acquire cross-sectional images of the microscopic structure of the esophagus, including Barretts esophagus (BE) and associated dysplasia. We developed a swallowable tethered capsule OCT endomicroscopy (TCE) device that acquires high-resolution images of entire gastrointestinal (GI) tract luminal organs. This device has a potential to become a screening method that identifies patients with an abnormal esophagus that should be further ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    16. Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo

      Explore Oxford Journals Cardiology
      Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo
      Aims Fibrin deposition and absent endothelium characterize unhealed stents that are at heightened risk of stent thrombosis. Optical coherence tomography (OCT) is increasingly used for assessing stent tissue coverage as a measure of healed stents, but cannot precisely identify whether overlying tissue represents physiological neointima. Here we assessed and compared fibrin deposition and persistence on bare metal stent (BMS) and drug-eluting stent (DES) using near-infrared fluorescence (NIRF) molecular imaging in ...
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      Mentions: Guillermo J. Tearney Massachusetts Institute of Technology Massachusetts General Hospital
    17. 1-15 of 44 1 2 3 »
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  4. About Giovanni J. Ughi

    Giovanni J. Ughi

    Giovanni J. Ughi is a researcher at the Medical Imaging Research Center at the University Hospital Gasthuisberg.  Dr. Ughi is pursing his PhD from the Catholic University of Leuven in Belgium.

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