1. Fujian Normal University

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    1. Mentioned In 46 Articles

    2. Impact of coronary plaque morphology on the precision of computational fractional flow reserve derived from optical coherence tomography imaging

      Impact of coronary plaque morphology on the precision of computational fractional flow reserve derived from optical coherence tomography imaging
      Background: Computational fractional flow reserve (FFR) was recently developed to expand the use of physiology-guided percutaneous coronary intervention (PCI). Nevertheless, current methods do not account for plaque composition. It remains unknown whether the numerical precision of computational FFR is impacted by the plaque composition in the interrogated vessels. Methods: This study is an observational, retrospective, cross-sectional study. Patients who underwent both optical coherence tomography (OCT) and FFR prior to intervention ...
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    3. Hemoporfin-Mediated Photodynamic Therapy for Port-Wine Stains: Multivariate Analysis of Clinical Efficacy and Optical Coherence Tomography Appearance

      Hemoporfin-Mediated Photodynamic Therapy for Port-Wine Stains: Multivariate Analysis of Clinical Efficacy and Optical Coherence Tomography Appearance
      Background: Hemoporfin-mediated photodynamic therapy (HMME-PDT) is reported to be effective and safe for port-wine stains (PWS). However, its efficacy is influenced by several factors and there is no appropriate method to evaluate efficacy so far. Therefore, this study explored the clinical efficacy of HMME-PDT for PWS on the face and neck and the feasibility of evaluating treatment potency with optical coherence tomography (OCT). Methods: A total of 211 PWS patients ...
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    4. Depth-independent internal fingerprint based on optical coherence tomography

      Depth-independent internal fingerprint based on optical coherence tomography
      Optical coherence tomography (OCT) was used for imaging three-dimensional fingerprint to overcome the effects of different skin states and fake fingerprint. However, the OCT-based fingerprint features depend on the depth of fingertip skin which is still challenging for biometric recognition and encryption. In this work, we presented a new approach of maximum intensity projection (MIP) image of the epidermal-dermal junction (DEJ) to extract the internal fingerprint that is independent of ...
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    5. Optical coherence hyperspectral microscopy with a single supercontinuum light source

      Optical coherence hyperspectral microscopy with a single supercontinuum light source
      In the paper, we have developed an optical coherence hyperspectral microscopy with a single supercontinuum light source. The microscopy consists of optical coherence tomography (OCT) and hyperspectral imaging (HSI), which can visualize the structural and functional characteristics of biological tissues. The 500-700 nm band is selected for HSI and OCT imaging, where HSI enables imaging of oxygen saturation and hemoglobin (Hb) content, while OCT acquires structural characteristics to assess the ...
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    6. Quantitative analysis of vascular changes during photoimmunotherapy using speckle variance optical coherence tomography (SV-OCT)

      Quantitative analysis of vascular changes during photoimmunotherapy using speckle variance optical coherence tomography (SV-OCT)
      Near-infrared (NIR) photoimmunotherapy (NIR-PIT) is an emerging cancer therapy based on a monoclonal antibody and phthalocyanine dye conjugate. Direct tumor necrosis and immunogenic cell death occur during NIR irradiation. However, the alteration of tumor blood vessels and blood volume inside the blood vessels induced by the NIR-PIT process is still unknown. In our study, a speckle variance (SV) algorithm combined with optical coherence tomography (OCT) technology was applied to monitor ...
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    7. Orthogonal‐polarization‐gating optical coherence tomography for human sweat ducts in vivo

      Orthogonal‐polarization‐gating optical coherence tomography for human sweat ducts in vivo
      We propose an orthogonal‐polarization‐gating optical coherence tomography (OPGOCT) for human sweat ducts in vivo . OPG‐OCT is composed of the orthogonal linearly polarized light of a sample arm individually interfering with orthogonal linearly polarized lights of the reference arms, where OPG‐OCT induces two images, one reflecting the projection intensity and the other the horizontal linear diattenuation (HLD). The results demonstrate that OPG‐OCT projection intensity could improve ...
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    8. Toward image quality assessment in optical coherence tomography (OCT) of rat kidney

      Toward image quality assessment in optical coherence tomography (OCT) of rat kidney
      Background Optical coherence tomography (OCT) is a useful tool for the evaluation of structure and function of the kidney, but the image quality can be affected by many factors. Objective The objective of this study was to assess the image quality of different OCT systems in OCT imaging of the living kidney. Methods One swept-source OCT (SSOCT) of 1300nm, one spectral domain OCT (SDOCT) of 1300nm and another of 900nm ...
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    9. Optical coherent tomography to evaluate the degree of inflammation in a mouse model of colitis

      Optical coherent tomography to evaluate the degree of inflammation in a mouse model of colitis
      Background: There is an urgent need to develop a noninvasive imaging technique for the diagnosis of early inflammatory lesions or early and real-time microscopic assessment before selecting the most representative biopsy sites. Methods: In this study, a dextran sulfate sodium colitis model was developed, and intestinal histological damage scores measured the degree of inflammation in colitis. According to these scores, 6 parameters were designed for hematoxylin and eosin (HE) sections ...
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    10. Quantitative assessment of skin swelling using optical coherence tomography

      Quantitative assessment of skin swelling using optical coherence tomography
      Background Preclinical and clinical studies suggest that optical coherence tomography (OCT) is a useful tool to visualize inflammatory conditions. Objective The objective of this study was to evaluate the usefulness of combining OCT and various image processing techniques for quantitative assessment of histamine-induced tissue swelling. Methods Both time-domain and frequency-domain OCT were used on a mouse ear model. The ear thickness and volume before and after histamine challenge were determined ...
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    11. Depth-resolved mapping of muscular bundles in myocardium pulmonary junction using optical coherence tomography

      Depth-resolved mapping of muscular bundles in myocardium pulmonary junction using optical coherence tomography
      Atrial fibrillation (AF) is the most common cardiac arrhythmia and has high patient morbidity. One of the root causes of AF is initiating triggers from atrial myocardium extending into the pulmonary veins. Visualizing the muscular bundles of myocardial extension is essential to guide the catheter radio-frequency ablation and confirm the curative tissue necrosis thereafter. We applied optical coherence tomography (OCT) for direct visualization of cardial muscle extension in myocardium pulmonary ...
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    12. Reform and practice of optical coherence tomography (OCT) system-driven teaching for optoelectronic instrument principle and design

      Reform and practice of optical coherence tomography (OCT) system-driven teaching for optoelectronic instrument principle and design
      Optoelectronic instrument principle and design includes the optical, mechanical, electrical and count modules for one system. We change traditional mode of customary specialty course design for only taking the cell design ability into account. Optical coherence tomography (OCT) can provide high-resolution 3D imaging system and wide application for tissue in vivo. In this work, we carry out OCT system driven teaching into execution in the course design teaching, and decompose ...
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    13. Single camera spectral domain polarization-sensitive optical coherence tomography based on orthogonal channels by time divided detection

      Single camera spectral domain polarization-sensitive optical coherence tomography based on orthogonal channels by time divided detection
      We demonstrate a simple polarization-sensitive spectral-domain optical coherence tomography implement by using a single line-scan camera based on time divided detection. Two light shutters were placed on the dual assembly reference arm that provides a divided detection between the orthogonal vertical and horizontal polarized lights. The relative reflectivity and the retardance information were available by recombining the two orthogonal polarization images. This system can be employed to implement high speed ...
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    14. A Correlation Study between Two Adjacent Same-Meridian Acupoints after Laser-Needle Acupuncture with Optical Coherence Tomography and Diffuse Reflectance Spectra

      A Correlation Study between Two Adjacent Same-Meridian Acupoints after Laser-Needle Acupuncture with Optical Coherence Tomography and Diffuse Reflectance Spectra
      This study is to investigate the correlations among Sanjian (LI3), Hegu (LI4), and Yangxi (LI5) acupoints and their corresponding nonacupoints on the Yangming Large Intestine Meridian of Hand before and after laser irradiation using optical coherence tomography (OCT) and diffuse reflectance spectra. The experiment was conducted on 10 healthy people. A 658nm laser with 50mW output power was used for irradiating LI4, LI5 acupoints and their corresponding nonacupoints. As to ...
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    15. A method to improve the measurement stability of scattering coefficients in lip with optical coherence tomography

      A method to improve the measurement stability of scattering coefficients in lip with optical coherence tomography
      Optical coherence tomography (OCT) is a non-invasive imaging technique that provides real-time two- and three-dimensional images of scattering tissues with micrometer resolution. Scattering coefficient is estimated based on the slope of OCT dependent of depth. However, stability of the OCT signal slope is dependent on tissue heterogeneity. Our work is to provide a method of combining post-processing Fourier filtration with automatic identification of fitting range to reduce the effect of ...
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    16. Imaging Spinal Structures With Polarization-Sensitive Optical Coherence Tomography

      Imaging Spinal Structures With Polarization-Sensitive Optical Coherence Tomography
      Impact Statement: We investigate polarization-sensitive optical coherence tomography (PS-OCT) to obtain both intensity and polarization contrast images of in vivo and ex vivo spinal structures like subcutaneous fat, supraspinous ligament, interspinous ligament, ligamentum flavum, dura, and spinal cord in a piglet model. The PS-OCT can provide enhanced contrast characteristic structures compared to the intensity OCT; therefore it has the potential for guidance in spine interventional procedures. Abstract: We investigate polarization-sensitive ...
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  2. About Fujian Normal University

    Fujian Normal University

    Fujian Normal University is a key institution of higher learning in Fujian with a century-old history and a glorious tradition, Fujian Normal University (FNU) has been hailed as the province’s “cradle of teachers.” Tracing its origin back to Fujian Superior Normal School, founded in 1907 by the famous late-Qing scholar Chen Baochen, who once served as the teacher of China’s last emperor, FNU is Fujian’s oldest university and one of China’s most time-honored teachers’ colleges. After the founding of the People’s Republic of China, the school, which by then had been renamed Fujian Provincial Normal College, merged in 1953 with such celebrated centers of learning as Fukian Christian University and Hua Nan Women’s College to form a new and significantly expanded Fujian Normal College, which acquired its current name of Fujian Normal University in 1972