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    1. Mentioned In 91 Articles

    2. Wide-Field Swept-Source Optical Coherence Tomography Angiography Analysis of the Periarterial Capillary-Free Zone in Branch Retinal Vein Occlusion

      Wide-Field Swept-Source Optical Coherence Tomography Angiography Analysis of the Periarterial Capillary-Free Zone in Branch Retinal Vein Occlusion
      Purpose : To investigate the characteristics of the retinal periarterial capillary-free zone (paCFZ) with wide-field swept-source optical coherence tomography angiography (SS-OCTA) in eyes with branch retinal vein occlusion (BRVO). Methods : Seventy treatment-nave eyes with BRVO and 35 healthy eyes were included. The paCFZ areas, artery calibers, and areas of the major arteries in the unaffected quadrants of BRVO eyes were measured in 12 12-mm SS-OCTA images and compared with those of ...
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      Mentions: Fudan University
    3. Decreased Retinal Vascular Density in Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI): An Optical Coherence Tomography Angiography (OCTA) Study

      Decreased Retinal Vascular Density in Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI): An Optical Coherence Tomography Angiography (OCTA) Study
      Background: To explore the retinal vascular density changes in Alzheimer's disease (AD) and mild cognitive impairment (MCI) patients using optical coherence tomography angiography (OCTA). Methods: We recruit 62 AD patients, 47 MCI patients, and 49 cognitively healthy controls (HC) in this study. All participants in the study received a comprehensive ophthalmological and neurological evaluation, including global cognitive screening, as well as the Mini-Mental State Examination (MMSE), and completed the ...
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    4. Retinal and Choroidal Thickness in relation to C-Reactive Protein on Swept-Source Optical Coherence Tomography

      Retinal and Choroidal Thickness in relation to C-Reactive Protein on Swept-Source Optical Coherence Tomography
      Purpose . To evaluate the relationships between C-reactive protein (CRP) and retinal and choroidal thickness by swept-source optical coherence tomography (SS-OCT). Methods . The participants included in the prospective cross-sectional study underwent a comprehensive ophthalmic examination. Based on the CRP values, the subjects were divided into the CRP (+) group (mg/L) and the CRP () group (mg/L). The retinal and choroidal thickness was compared between the two groups. Results . This study enrolled ...
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      Mentions: Fudan University
    5. Feasibility of microscope-integrated swept-source optical coherence tomography in canaloplasty

      Feasibility of microscope-integrated swept-source optical coherence tomography in canaloplasty
      Background: Several researchers have used commercial microscope-integrated optical coherence tomography (OCT) systems in glaucoma surgery, including ab interno trabeculectomy and canaloplasty. However, the 840 nm wavelength light source of the OCT systems is not ideal for imaging the anterior chamber angle structures because of its limited penetration. We evaluated the potential value of a microscope-integrated swept-source OCT system with a 1,310 nm center-wavelength light in canaloplasty for glaucoma. Methods ...
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    6. Optical coherence tomography for the early detection of colorectal dysplasia and cancer: validation in a murine model

      Optical coherence tomography for the early detection of colorectal dysplasia and cancer: validation in a murine model
      Background: There is an urgent need to develop a non-invasive imaging technique for detecting colorectal dysplasia and cancer. Technology for early and real-time microscopic assessments to select the most representative biopsy sites would also be of clinical value. In this study, we explored the sensitivity of optical coherence tomography (OCT) in detecting local lesions to demonstrate its potential for the early detection of colorectal dysplasia and cancer. Methods: An azoxymethane ...
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      Mentions: Fudan University
    7. A Novel Approach to Quantitative Evaluation of Outer Retinal Lesions Via a New Parameter “Integral” in Spectral Domain Optical Coherence Tomography

      A Novel Approach to Quantitative Evaluation of Outer Retinal Lesions Via a New Parameter “Integral” in Spectral Domain Optical Coherence Tomography
      Purpose : The purpose of this study was to design a new parameter integral to quantitatively evaluate the spatial cumulative reflectivity of the outer retinal layers in optical coherence tomography (OCT), and to investigate its role in the detection of outer retinal diseases. Methods : This was a cross-sectional study. Fovea-centered line OCT scans were performed on 60 eyes of 60 healthy volunteers and 44 eyes of 44 patients diagnosed with outer ...
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      Mentions: Fudan University
    8. Alterations in the Retinal Vascular Network and Structure in MOG Antibody-Associated Disease: An Optical Coherence Tomography Angiography Study

      Alterations in the Retinal Vascular Network and Structure in MOG Antibody-Associated Disease: An Optical Coherence Tomography Angiography Study
      Background: To determine retinal vessel density in patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). Methods: Twenty-five patients with MOGAD and 20 healthy participants were enrolled. Patients with MOGAD were divided into myelin oligodendrocyte glycoprotein antibody (MOG-Ab)-positive eyes with a history of optic neuritis (ON; MOG-Ab-ON+ group) or without a history of ON (MOG-Ab-ON- group). Visual function, retinal vessel densities, and thickness were measured. Results: The retinal nerve fiber ...
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      Mentions: Fudan University
    9. Positive-Aware Lesion Detection Network with Cross-scale Feature Pyramid for OCT Images

      Positive-Aware Lesion Detection Network with Cross-scale Feature Pyramid for OCT Images
      Optical coherence tomography (OCT) is an important imaging technique in ophthalmology, and accurate detection of retinal lesions plays an important role in computer-aided diagnosis. However, the particularities of retinal lesions, such as their complex appearance and large variation of scale, limit the successful application of conventional deep learning-based object detection networks for OCT lesion detection. In this study, we propose a positive-aware lesion detection network with cross-scale feature pyramid for ...
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      Mentions: Fudan University
    10. Comparison of the Meibomian Gland Openings by Optical Coherence Tomography in Obstructive Meibomian Gland Dysfunction and Normal Patients

      Comparison of the Meibomian Gland Openings by Optical Coherence Tomography in Obstructive Meibomian Gland Dysfunction and Normal Patients
      Purpose: The aim of this study was to use swept-source anterior segment optical coherence tomography (OCT) to explore imaging the meibomian gland openings and to identify their in vivo characteristics in patients with obstructive meibomian gland dysfunction (MGD) and healthy participants. Methods: We enrolled 49 patients with MGD and 54 health controls in this case-control study. Each participant underwent slit-lamp examination, meibography, and OCT scanning. Sixteen patients with MGD underwent ...
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      Mentions: Fudan University
    11. Imaging depth extension of optical coherence tomography in rabbit eyes using optical clearing agents

      Imaging depth extension of optical coherence tomography in rabbit eyes using optical clearing agents
      Optical coherence tomography has become an indispensable diagnostic tool in ophthalmology for imaging the retina and the anterior segment of the eye. However, the imaging depth of optical coherence tomography is limited by light attenuation in tissues due to optical scattering and absorption. In this study of rabbit eye both ex vivo and in vivo , optical coherence tomography imaging depth of the anterior and posterior segments of the eye was ...
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    12. Microscope-integrated Intraoperative Optical Coherence Tomography for Anterior Segment Surgical Maneuvers

      Microscope-integrated Intraoperative Optical Coherence Tomography for Anterior Segment Surgical Maneuvers
      Purpose : To evaluate the potential value of microscope-integrated optical coherence tomography (MI-OCT) in anterior segment surgical maneuvers. Methods : Twenty-four ophthalmology residents, who were randomly and evenly divided into two groups, performed four anterior segment surgical maneuvers (corneal tunnel, scleral tunnel, simple corneal suture, and corneal laceration repair) on porcine eyes with (group B) or without (group A) real-time MI-OCT feedback. All residents performed the maneuvers again without MI-OCT. Results : Compared ...
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    13. Diagnostic Performance of Confocal Laser Endomicroscopy for the Detection of Bladder Cancer: Systematic Review and Meta-Analysis

      Diagnostic Performance of Confocal Laser Endomicroscopy for the Detection of Bladder Cancer: Systematic Review and Meta-Analysis
      Objective: To systematically evaluate the diagnostic efficacy of confocal laser endomicroscopy (CLE) in detection of bladder cancer. Methods: A systematic literature search on CLE in diagnosing bladder cancer in PubMed, Embase, and the Cochrane Library databases was performed. A bivariate meta-regression model was used for meta-analysis to evaluate the pooled diagnostic value of CLE. Results: A total of 5 eligible studies involving 302 lesions were available for this meta-analysis. In ...
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      Mentions: Fudan University
    14. Relationship between photoreceptor layer changes before half-dose photodynamic therapy and functional and anatomic outcomes in central serous chorioretinopathy

      Relationship between photoreceptor layer changes before half-dose photodynamic therapy and functional and anatomic outcomes in central serous chorioretinopathy
      Objectives To investigate the relationship between photoreceptor layer (PRL) changes before half-dose photodynamic therapy (PDT) and functional and anatomic outcomes in central serous chorioretinopathy (CSC). Methods Baseline PRL changes were classified based on optical coherence tomography: (1) smooth PRL outer border without a foveal PRL defect; (2) smooth PRL outer border with a foveal PRL defect; (3) granulated PRL outer border and (4) scattered dots of PRL. The best-corrected visual ...
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  2. About Fudan University

    Fudan University

    Fudan University is located in Shanghai and is one of the oldest and most selective universities in China, and is a member of the C9 League. Its institutional predecessor was founded in 1905, shortly before the end of China's imperial Qing dynasty. Fudan University is composed of four campuses, including Handan, Fenglin, Zhangjiang, and Jiangwan.