1. Frederique Vanholsbeeck

    0 Comments Leave a Comment

    1-15 of 31 1 2 »
    1. Mentioned In 31 Articles

    2. Quantum Optical Coherence Tomography using two photon joint spectrum detection (JS-Q-OCT)

      Quantum Optical Coherence Tomography using two photon joint spectrum detection (JS-Q-OCT)
      Quantum Optical Coherence Tomography (Q-OCT) is the non-classical counterpart of Optical Coherence Tomography (OCT) - a high-resolution 3D imaging technique based on white-light interferometry. Because Q-OCT uses a source of frequency-entangled photon pairs, not only is the axial resolution not affected by dispersion mismatch in the interferometer, but is also inherently improved by a factor of square root of two. Unfortunately, practical applications of QOCT are hindered by image-scrambling artefacts and ...
      Read Full Article
    3. Optical coherence tomography imaging of evoked neural activity in sciatic nerve of rat

      Optical coherence tomography imaging of evoked neural activity in sciatic nerve of rat
      Significance: Imaging neural activity in myelinated tissue using optical coherence tomography (OCT) creates exciting possibilities for functional imaging in the peripheral and central nervous systems. Aim: To investigate changes in OCT images in response to evoked neural activity in sciatic nerve of rat in vitro. Approach: M-scans were obtained on peripheral nerves of rat using a swept source polarisation sensitive OCT system, while a nerve cuff acquired electrical neural recordings ...
      Read Full Article
    4. Quantum-inspired detection for Spectral Domain Optical Coherence Tomography

      Quantum-inspired detection for Spectral Domain Optical Coherence Tomography
      The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve high-sensitivity imaging at low intensity levels, we adapt a detection scheme - which is used in quantum optics for providing information about spectral correlations of photons - into a standard spectral domain OCT system. This ...
      Read Full Article
    5. Optical coherence tomography complements confocal microscopy for investigation of multicellular tumour spheroids

      Optical coherence tomography complements confocal microscopy for investigation of multicellular tumour spheroids
      Knowledge of optical properties, such as the refractive index (RI), of biological tissues is important in optical imaging, as they influence the distribution and propagation of light in tissue. To accurately study the response of cancerous cells to drugs, optimised imaging protocols are required. This study uses a simple custom-built spectral domain optical coherence tomography (OCT) system to conduct RI measurements of multicellular spheroids, three-dimensional (3D) in-vitro culture systems, of ...
      Read Full Article
    6. Refractive index measurements of multicellular tumour spheroids using optical coherence tomography: dependence on growth phase and size

      Refractive index measurements of multicellular tumour spheroids using optical coherence tomography: dependence on growth phase and size
      Knowledge of optical properties, such as the refractive index (RI), of biological tissues is important in optical imaging, as they influence the distribution and propagation of light in tissue. To accurately study the response of cancerous cells to drugs, optimised imaging protocols are required. This study uses a simple custom-built spectral domain optical coherence tomography (OCT) system to conduct RI measurements of multicellular spheroids, three-dimensional in-vitro culture systems, of the ...
      Read Full Article
    7. Quantifying birefringence in the bovine model of early osteoarthritis using polarisation-sensitive optical coherence tomography and mechanical indentation

      Quantifying birefringence in the bovine model of early osteoarthritis using polarisation-sensitive optical coherence tomography and mechanical indentation
      Recent studies have shown potential for using polarisation sensitive optical coherence tomography (PS-OCT) to study cartilage morphology, and to be potentially used as an in vivo , non-invasive tool for detecting osteoarthritic changes. However, there has been relatively limited ability of this method to quantify the subtle changes that occur in the early stages of cartilage degeneration. An established mechanical indenting technique that has previously been used to examine the microstructural ...
      Read Full Article
    8. Extracting morphometric information from rat sciatic nerve using optical coherence tomography

      Extracting morphometric information from rat sciatic nerve using optical coherence tomography
      We apply three optical coherence tomography (OCT) image analysis techniques to extract morphometric information from OCT images obtained on peripheral nerves of rat. The accuracy of each technique is evaluated against histological measurements accurate to +/-1 m. The three OCT techniques are: 1) average depth resolved profile (ADRP); 2) autoregressive spectral estimation (AR-SE); and, 3) correlation of the derivative spectral estimation (CoD-SE). We introduce a scanning window to the ADRP ...
      Read Full Article
    9. Using polarisation-sensitive optical coherence tomography and mechanical indentation to assess cartilage degeneration in the bovine model of early osteoarthritis

      Using polarisation-sensitive optical coherence tomography and mechanical indentation to assess cartilage degeneration in the bovine model of early osteoarthritis
      Recent studies have shown potential for using polarisation sensitive optical coherence tomography (PS-OCT) to study cartilage morphology, and this presents a useful real-time non-invasive tool for detecting osteoarthritic changes. However, there has been relatively limited ability of this method to quantify the subtle changes in the early stages of joint degeneration. In this study, we investigate the ability of PS-OCT to detect microscale degenerative changes in cartilage, following compression, using ...
      Read Full Article
    10. Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data

      Dispersion mapping as a simple postprocessing step for Fourier domain Optical Coherence Tomography data
      Optical Coherence Tomography (OCT) was originally conceived as a volumetric imaging method. Quickly, OCT images went beyond structural data and started to provide functional information about an object enabling for example visualization of blood flow or tissue elasticity. Minimal or no need for system alterations make functional OCT techniques useful in performing multimodal imaging, where differently contrasted images are produced in a single examination. We propose a method that further ...
      Read Full Article
    11. Dispersion measurements in ocular media using a dual-wavelength swept source optical coherence tomography system

      Dispersion measurements in ocular media using a dual-wavelength swept source optical coherence tomography system
      Optical coherence tomography (OCT) has proved to be a powerful tool for the detection of microstructure in tissue. Label-free tissue differentiation on a micron scale is a promising and powerful technique for segmentation. This Letter describes a technique using a dual-wavelength OCT system to image the eye. We measure the walk-off between interfaces in A-scans, taken at two different wavelengths, to calculate the average group velocity dispersion parameter of each ...
      Read Full Article
    12. 4D imaging of cardiac trabeculae contracting in vitro using gated OCT

      4D imaging of cardiac trabeculae contracting in vitro using gated OCT
      Cardiac trabeculae are widely used as experimental muscle preparations for studying heart muscle. However, their geometry (diameter, length, and shape) can vary not only amongst samples, but also within a sample, leading to inaccuracies in estimating their stress production, volumetric energy output, and/or oxygen consumption. Hence, it is desirable to have a system that can accurately image each trabecula in vitro during an experiment. To this end, we constructed ...
      Read Full Article
    13. Simple and versatile long range swept source for optical coherence tomography applications

      Simple and versatile long range swept source for optical coherence tomography applications
      We present a versatile long coherence length swept-source laser design for optical coherence tomography applications. This design consists of a polygonal spinning mirror and an optical gain chip in a modified LittmanMetcalf cavity. A narrowband intra-cavity filter is implemented through multiple passes off a diffraction grating set at grazing incidence. The key advantage of this design is that it can be readily adapted to any wavelength regions for which broadband ...
      Read Full Article
    14. 1-15 of 31 1 2 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Frederique Vanholsbeeck

    Frederique Vanholsbeeck

    Frederique Vanholsbeeck is with the Department of Physics at the University of Auckland. Dr. Vanholsbeeck's principal research area is now biophotonics, i.e., using light to observe and to understand physiological processes.