1. Francesco Prati

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    1. Mentioned In 108 Articles

    2. OPtical Coherence Tomography Guided Coronary Stent IMplantation Compared to Angiography: A Multicenter Randomized TriaL in PCI

      Explore eurointervention.pcronline.com Cardiology
      OPtical Coherence Tomography Guided Coronary Stent IMplantation Compared to Angiography: A Multicenter Randomized TriaL in PCI
      AIMS: Randomized trials have demonstrated improvement in clinical outcomes with intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) compared with angiography-guided PCI. The ILUMIEN III trial demonstrated non-inferiority of an optical coherence tomography (OCT)- versus IVUS-guided PCI strategy in achieving similar post-PCI lumen dimensions. ILUMIEN IV is a large-scale, multicenter, randomized trial designed to demonstrate the superiority of OCT- versus angiography-guided stent implantation in patients with high-risk clinical characteristics (diabetes ...
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      Mentions: Columbia University Mount Sinai School of Medicine Cardiovascular Research Foundation

    3. Clinical outcomes of calcified nodules detected by optical coherence tomography

      Explore eurointervention.pcronline.com Cardiology
      Clinical outcomes of calcified nodules detected by optical coherence tomography
      Aims: The goal of the present post hoc analysis of the CLIMA registry was to establish the relationship between calcified nodules (CNs) with (CND) or without (CNWD) disruption of the superficial intimal fibrous layer and one-year occurrence of target lesion myocardial infarction (MI) and/or cardiac death. Methods and results: CND and CNWD were identified based on the presence or absence of superficial irregularities indicative of disruption of the intimal ...
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      Mentions: Corrado Tamburino University of Catania Fernando Alfonso

    4. Prevalence and quantitative assessment of macrophages in coronary plaques

      Explore Home - Springer Cardiology
      Prevalence and quantitative assessment of macrophages in coronary plaques
      Although optical coherence tomography (OCT) proved to be able to identify macrophage clusters, there are no available data on the possibility to obtain reproducible measurements of their circumferential extension and location. The purpose of the present post-hoc analysis of the CLIMA study was to revise the clinical and demographic variables of patients having coronary plaques with macrophages and to investigate the reproducibility of their quantitative assessment. A total of 577 ...
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      Mentions: Corrado Tamburino University of Catania University of Bologna

    5. Comparison between different approaches to evaluate fibrous cap thickness in sequential OCT studies

      Explore Edizioni Minerva Medica Cardiology
      Comparison between different approaches to evaluate fibrous cap thickness in sequential OCT studies
      BACKGROUND: In this in vivo human study we tested the reproducibility for optical coherence tomography (OCT) assessment of lumen area (LA) and plaque components measurements, such as lipid arc extension and fibrous cap thickness (FCt). METHODS: We tested the variability of LA, lipid arc and FCt assessments in two repeated OCT pullbacks from the same diseased coronary segment matched using fiduciary anatomical landmarks. In particular, for the reliability of minimal ...
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      Mentions: Francesco Prati

    6. Optical coherence tomography assessment of macrophages accumulation in non-ST-segment elevation acute coronary syndromes

      Explore LWW Online Cardiology
      Optical coherence tomography assessment of macrophages accumulation in non-ST-segment elevation acute coronary syndromes
      Aims To investigate in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) the prevalence and the features of optical coherence tomography (OCT)-detected macrophages accumulation in culprit plaques as compared with nonculprit plaques (NCP). Methods The study is a post-hoc analysis of a prospective study aimed at evaluating the relationship between aortic inflammation as assessed by 18 F-fluorodeoxyglucose-PET and features of coronary plaque vulnerability as assessed by OCT. We enrolled ...
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      Mentions: University of Bologna Francesco Prati

    7. Effects of stent postdilatation during primary PCI for STEMI: Insights from coronary physiology and optical coherence tomography

      Explore Wiley Online Library Cardiology
      Effects of stent postdilatation during primary PCI for STEMI: Insights from coronary physiology and optical coherence tomography
      Objectives This study aimed to assess the impact of stent optimization by NC‐balloon postdilatation (PD) during primary‐PCI for STEMI with the use of coronary physiology and intracoronary imaging. Methods This was a prospective observational study ( ClinicalTrials.gov :NCT02788396). Optical coherence tomography (OCT) and physiological measurements were performed immediately before and after PD with the operators blinded to all measurements. The index of microcirculatory resistance (IMR), coronary flow reserve ...
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      Mentions: Francesco Prati

    11. Role of optical coherence tomography for distal left main stem angioplasty

      Explore Wiley Online Library Cardiology
      Role of optical coherence tomography for distal left main stem angioplasty
      Objective The objective is to analyze the acute and midterm angiographic outcome of percutaneous treatment of left main coronary stem (LM‐PCI) guided by optical coherence tomography (OCT). Background LM‐PCI is a complex procedure, and several anatomical factors may impair its outcome. Intravascular imaging is emerging as a useful tool to guide the procedure. Methods We conducted a retrospective analysis of patients undergoing LM‐PCI at three European centers ...
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      Mentions: Fernando Alfonso Francesco Prati

    12. Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent

      Explore eurointervention.pcronline.com Cardiology
      Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent
      This consensus document is the second of two reports summarizing the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) on the clinical use of intracoronary imaging including intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near infrared spectroscopy (NIRS)-IVUS. Beyond guidance of stent selection and optimization of deployment, invasive imaging facilitates angiographic interpretation and may guide treatment in acute coronary syndrome. Intravascular ...
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      Mentions: Imperial College London Columbia University Cardiovascular Research Foundation

    13. Relationship between coronary plaque morphology of the left anterior descending artery and 12 months clinical outcome: the CLIMA study

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      Relationship between coronary plaque morphology of the left anterior descending artery and 12 months clinical outcome: the CLIMA study
      Aims The CLIMA study, on the relationship between c oronary p l aque morphology of the left anter i or descending artery and twelve m onths clinic a l outcome, was designed to explore the predictive value of multiple high-risk plaque features in the same coronary lesion [minimum lumen area (MLA), fibrous cap thickness (FCT), lipid arc circumferential extension, and presence of optical coherence tomography (OCT)-defined macrophages] as detected ...
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      Mentions: Massachusetts General Hospital Abbot Corrado Tamburino

    14. Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent

      Explore Journals Cardiology
      Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Intervent
      This consensus document is the second of two reports summarizing the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) on the clinical use of intracoronary imaging including intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near infrared spectroscopy (NIRS)-IVUS. Beyond guidance of stent selection and optimization of deployment, invasive imaging facilitates angiographic interpretation and may guide treatment in acute coronary syndrome. Intravascular ...
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      Mentions: Imperial College London Cardiovascular Research Foundation Gary S. Mintz

    15. Flying through the coronary easily

      Explore journals.viamedica.pl Cardiology
      Flying through the coronary easily
      Optical coherence tomography (OCT) has been waived as a breakthrough in coronary imaging. With its superb resolution in the range of 1020 m, OCT has proven to be a valuable technique in guiding coronary interventions [13]. Apart from this, among other intracoronary technical solutions, OCT certainly has the greatest potential in studying atherosclerosis in vivo, and identifying subjects with vulnerable lesions which leave patients prone to developing hard coronary events ...
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      Mentions: Francesco Prati

    16. Clinical use of intracoronary imaging. Part 1: guidance and optimization of coronary interventions. An expert consensus document of the European Association of Percutaneous Cardiovascular Interventions

      Explore Journals Cardiology
      Clinical use of intracoronary imaging. Part 1: guidance and optimization of coronary interventions. An expert consensus document of the European Association of Percutaneous Cardiovascular Interventions
      his Consensus Document is the first of two reports summarizing the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) on the clinical use of intracoronary imaging including intravascular ultrasound (IVUS) and optical coherence tomography (OCT). The first document appraises the role of intracoronary imaging to guide percutaneous coronary interventions (PCIs) in clinical practice. Current evidence regarding the impact of intracoronary imaging guidance on ...
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      Mentions: Cardiovascular Research Foundation Gary S. Mintz Carlo Di Mario
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  4. About Francesco Prati

    Francesco Prati, MD, is from the San Giovanni-Addolorata Hospital in Rome.

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  6. Quotes

    1. The technique allows high-resolution arterial-wall imaging in the range of 10-20 microns, allowing penetrance into the arterial wall and visualisation of specific components of the atherosclerotic plaques, including calcification, fibrotic tissue, necrotic lipid pools and thrombotic components.
      In In search of the thrombosis-prone vulnerable plaque