1. Fernando Alfonso

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    1. Mentioned In 60 Articles

    2. Optical Coherence Tomography Findings in Patients With Recanalized Coronary Thrombi Treated With Bioresorbable Vascular Scaffolds

      Optical Coherence Tomography Findings in Patients With Recanalized Coronary Thrombi Treated With Bioresorbable Vascular Scaffolds
      Introduction Recanalized coronary thrombi (RCT) are rarely recognized in real-world clinical practice. Incidence and functional significance of RCT remain unclear. High-resolution imaging modalities, such as optical coherence tomography (OCT), may provide novel insight to further characterize this unique phenomenon. 1 , 2 We present a case series of RCT treated with bioresorbable vascular scaffold (BVS). Case 1 A 75-year-old man with a previous history of an inferior myocardial infarction was admitted ...
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    3. Coronary artery aneurysm formation following implantation of a bioresorbable vascular scaffold for in-stent restenosis

      Coronary artery aneurysm formation following implantation of a bioresorbable vascular scaffold for in-stent restenosis
      Coronary artery aneurysm (CAA) formation is a rare complication of coronary intervention that may develop after implantation of bare-metal or drug-eluting stents. The etiology of this entity appears to be multifactorial and its prognosis is poorly understood, but it has been associated with an increased risk of stent thrombosis. To date few cases of CAAs related to bioresorbable vascular scaffold (BVS) implantation have been reported, and the development of CAA ...
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      Mentions: Fernando Alfonso
    4. Iatrogenic Coronary Artery Dissection Induced During Invasive Absolute Coronary Blood Flow Measurement: Optical Coherence Tomography Findings

      Iatrogenic Coronary Artery Dissection Induced During Invasive Absolute Coronary Blood Flow Measurement: Optical Coherence Tomography Findings
      A 65-year-old woman with previous history of hypertension was referred to our institution due to effort angina with a positive exercise stress test. Coronary angiography showed normal coronary arteries. A vasospasm provocation test with methylergonovine was negative. With the aim of assessing the state of microvasculature, absolute coronary blood flow by thermodilution was performed as previously described.
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      Mentions: Fernando Alfonso
    5. Multifaceted Presentation of Recurrent Spontaneous Coronary Artery Dissection Angiography and Optical Coherence Tomography Findings

      Multifaceted Presentation of Recurrent Spontaneous Coronary Artery Dissection Angiography and Optical Coherence Tomography Findings
      A 58-year-old woman with a previous history of hypertension, hypercholesterolemia, and cigarette smoking presented with a nonST-segmentelevation myocardial infarction with transient (nonpersistent) anterior ST-segmentelevation suggesting ischemia on the territory of the left anterior descending coronary artery. The coronary angiogram showed no signs of atherosclerosis but depicted severely tortuous coronary arteries with a focal lumen narrowing in the mid-segment of the left anterior descending coronary artery (Figure 1A). In addition, a ...
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      Mentions: Fernando Alfonso
    6. Multifaceted Presentation of Recurrent Spontaneous Coronary Artery Dissection Angiography and Optical Coherence Tomography Findings

      Multifaceted Presentation of Recurrent Spontaneous Coronary Artery Dissection Angiography and Optical Coherence Tomography Findings
      A 58-year-old woman with a previous history of hypertension, hypercholesterolemia, and cigarette smoking presented with a nonST-segmentelevation myocardial infarction with transient (nonpersistent) anterior ST-segmentelevation suggesting ischemia on the territory of the left anterior descending coronary artery. The coronary angiogram showed no signs of atherosclerosis but depicted severely tortuous coronary arteries with a focal lumen narrowing in the mid-segment of the left anterior descending coronary artery (Figure 1A). In addition, a ...
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      Mentions: Fernando Alfonso
    7. Mother-and-child catheter-facilitated optical coherence tomography: A novel approach to improve intracoronary imaging

      Mother-and-child catheter-facilitated optical coherence tomography: A novel approach to improve intracoronary imaging
      Background: Our aim was to prospectively analyze the usefulness of mother-and-child catheter approach with the GuideLiner (GL) catheter extension system to overcome some potential limitations associated with the use of optical coherence tomography (OCT). Methods: We included consecutive patients referred to our institution for coronary angiogram in whom OCT image acquisition was obtained using GL. From February 2015 to May 2016, a total of 19 procedures (18 patients) were prospectively ...
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      Mentions: Fernando Alfonso
    8. Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a randomised controlled trial

      Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a randomised controlled trial
      Background Percutaneous coronary intervention (PCI) is most commonly guided by angiography alone. Intravascular ultrasound (IVUS) guidance has been shown to reduce major adverse cardiovascular events (MACE) after PCI, principally by resulting in a larger postprocedure lumen than with angiographic guidance. Optical coherence tomography (OCT) provides higher resolution imaging than does IVUS, although findings from some studies suggest that it might lead to smaller luminal diameters after stent implantation. We sought ...
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    9. Neoatherosclerosis causing occlusive in-stent restenosis: Impact of intracoronary imaging in the intensity of lipid-lowering therapy

      Neoatherosclerosis causing occlusive in-stent restenosis: Impact of intracoronary imaging in the intensity of lipid-lowering therapy
      The unique physical properties of optical coherence tomography (OCT) make it a useful technique in the study of restenosis mechanisms. In fact, OCT is able to differentiate between neointimal proliferation and neoatherosclerosis within the stent. We report a rare case of occlusive neoatherosclerosis presenting beyond one year after a successful drug-eluting stent implantation. The impact of OCT findings in the clinical decision making process is emphasized.
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      Mentions: Fernando Alfonso
    10. Combined optical coherence tomography morphologic and fractional flow reserve hemodynamic assessment of non- culprit lesions to better predict adverse event outcomes in diabetes mellitus patients: COMBINE (OCT–FFR) prospective study. Rationale and design

      Combined optical coherence tomography morphologic and fractional flow reserve hemodynamic assessment of non- culprit lesions to better predict adverse event outcomes in diabetes mellitus patients: COMBINE (OCT–FFR) prospective study. Rationale and design
      Background Fractional flow reserve (FFR) is a widely used tool for the identification of ischaemia-generating stenoses and to guide decisions on coronary revascularisation. However, the safety of FFR-based decisions in high-risk subsets, such as patients with Diabetes Mellitus (DM) or vulnerable stenoses presenting thin-cap fibro-atheroma (TCFA), is unknown. This study will examine the impact of optical coherence tomography (OCT) plaque morphological assessment and the identification of TCFA, in combination with ...
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      Mentions: Fernando Alfonso
    11. Dynamic single gold nanoparticle visualization by clinical intracoronary optical coherence tomography

      Dynamic single gold nanoparticle visualization by clinical intracoronary optical coherence tomography
      The potential use of Gold Nanoparticles (GNPs) as contrast agents for clinical intracoronary frequency domain Optical Coherence Tomography (OCT) is here explored. The OCT contrast enhancement caused by GNPs of different sizes and morphologies has been systematically investigated and correlated with their optical properties. Among the different GNPs commercially available with plasmon resonances close to the operating wavelength of intracoronary OCT (1.3 m), Gold Nanoshells (GNSs) have provided the ...
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      Mentions: Fernando Alfonso
    12. Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography

      Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography
      Introduction Straightening of tortuous coronaries by intracoronary guidewires may generate intimal wrinkles or coronary pleating and lead to the development of different abnormal angiographic findings widely known as pseudostenosis or accordion effect. 1 We report the unique findings disclosed by optical coherence tomography (OCT) in 3 patients developing coronary pleating. Patient 1 An 84-year-old woman with severe aortic stenosis was referred for coronary angiography before transcatheter aortic valve implantation. A ...
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      Mentions: Fernando Alfonso
    13. Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography

      Coronary Pleating Mimicking Coronary Ruptures, Dissections, and Thrombi on Optical Coherence Tomography
      Introduction Straightening of tortuous coronaries by intracoronary guidewires may generate intimal wrinkles or coronary pleating and lead to the development of different abnormal angiographic findings widely known as pseudostenosis or accordion effect. We report the unique findings disclosed by optical coherence tomography (OCT) in 3 patients developing coronary pleating. Patient 1 An 84-year-old woman with severe aortic stenosis was referred for coronary angiography before transcatheter aortic valve implantation. A severe ...
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      Mentions: Fernando Alfonso
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  2. About Fernando Alfonso

    Fernando Alfonso

    Fernando Alfonso is an Interventional Cardiologist at the Cardiovascular Institute, San Carlos University Hospital, Madrid, Spain.